20 completed, 13 unknown, 5 recruiting, 3 active not recruiting. 6 Not applicable, 3 Phase 2, 2 Phase 3, 1 Early Phase 1, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 5, Not yet recruiting 1 |
| Phase 2 | 3 | Unknown 2, Recruiting 1 |
| Phase 3 | 2 | Completed 1, Recruiting 1 |
| Early Phase 1 | 1 | Withdrawn 1 |
| Phase 1 | 1 | Terminated 1 |
Follow High-Throughput Nucleotide Sequencing: new trials by email Literature Review of High-Throughput Nucleotide Sequencing trials Research Report on High-Throughput Nucleotide Sequencing
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Exploring the Impact of Genetic Variations on The Clinical Efficacy of Nalbuphine in Postoperative Pain Management Nalbuphine Injection, Next Generation Sequencing, whole exome sequencing - Cholecystectomy, Hernia, Abdominal | Phase 2 / Phase 3 | Recruiting | Dr. Asma Abdus Salam | 263 | 2025-09-01 | 2026-04-15 |
| Baker Gordon Syndrome Natural History Study Brain Magnetic Resonance Imaging (MRI), Whole Genome Sequencing, Induced Pluripotential Stem Cells - Rare Diseases, Autism or Autistic Traits | Recruiting | University of Missouri-Columbia | 50 | 2024-04-30 | 2026-06-03 | |
| Metagenomic Analysis of the Oral Microbiome in Patients With Oral Lichen Planus: A Pilot Study in the Turkish Population cytobrush, next-generation sequencing - Oral Lichen Planus | Completed | Kahramanmaras Sutcu Imam University | 13 | 2023-12-15 | 2025-08-22 | |
| Initiative for Clinical Long-read Sequencing Next-Generation Sequencing (NGS) - Genetic Predisposition | Not applicable | Not yet recruiting | University Hospital Tuebingen | 500 | 2023-12-01 | 2023-09-29 |
| Melphalan on Disease Burden Measured by Next Generation Sequencing Before AHCT (Autologous Hematopoietic Cell Transplant) for Multiple Myeloma Evomela, Next Generation Sequencing, Prochlorperazine - Multiple Myeloma | Early Phase 1 | Withdrawn | Koen van Besien | 2023-09-01 | 2024-04-02 | |
| CML Pediatric ITK Response According to Molecular Identification at Diagnosis Next Generation Sequencing (DNA and RNA) - Chronic Myeloid Leukemia | Unknown | University Hospital, Bordeaux | 88 | 2023-02-27 | 2024-08-14 | |
| Quest for Tumour Evolution of Non-small Cell Lung Cancer Next generation sequencing - Non-small Cell Lung Cancer | Active not recruiting | The University of Hong Kong | 60 | 2023-02-15 | 2023-04-13 | |
| Precision Medicine for Every Child With Cancer Whole Genome Sequencing, RNA seq, DNA Methylation - Childhood Cancer, Childhood Solid Tumor | Recruiting | Australian & New Zealand Children's Haematology/Oncology Group | 3500 | 2022-12-16 | 2024-07-17 | |
| Breast Cancer After Ovarian Cancer During and/or After Therapy: Genomic Evaluation Next-generation sequencing (NGS) assay TruSight Oncology 500 (TSO 500). - BRCA-Associated Breast Carcinoma | Unknown | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 10 | 2022-03-01 | 2023-03-10 | |
| Breast Cancer, Omics, and Precision Medicine Next Generation Sequencing and Network Analysis - Breast Cancer | Phase 2 | Unknown | University of Campania Luigi Vanvitelli | 200 | 2022-01-01 | 2021-08-13 |
| A Screening Study Targeting Tumor-specific Antigens blood collection for research (next generation sequencing [NGS]), blood collection for research (HLA typing), blood collection for research (circulating tumor DNA [ctDNA]) - Metastatic Colorectal Cancer, Stage II/III Colon Cancer | Completed | Gritstone bio, Inc. | 22 | 2021-12-14 | 2022-10-18 | |
| The Registry of Genetic Alterations of Taiwan Biliary Tract Cancer next-generation sequencing - Biliary Tract Cancer (BTC) | Active not recruiting | National Health Research Institutes, Taiwan | 480 | 2021-10-25 | 2026-07-02 | |
| Spanish Study for Molecular Characterization of Thyroid Carcinoma Immunohistochemistry (IHC), Fluorescence In-Situ Hybridization (FISH), Oncomine Focus Assay Platform with 52 genes - Differentiated Thyroid Carcinoma, Medullary Thyroid Carcinoma | Unknown | Grupo Español de Tratamiento de Tumores de Cabeza y Cuello | 150 | 2021-06-14 | 2024-09-19 | |
| Correlative Study on Cancer Patients and Healthcare Professionals Exposed to Infection by Severe Acute Respiratory Syndrome-Corona Virus-2 (SARS-Cov-2), COVID-19 Causative Agent. serological test, Rapid molecular test, Next generation Sequencing (NGS) analysis - COVID-19, SARS-CoV-2 | Unknown | Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS | 500 | 2020-03-27 | 2020-04-15 | |
| Molecular Profiling of Advanced Soft-tissue Sarcomas Nilotinib, Ceritinib, Capmatinib - Soft Tissue Sarcoma | Phase 3 | Completed | Institut National de la Santé Et de la Recherche Médicale, France | 603 | 2019-10-19 | 2026-04-29 |
| Impact of Concomitant Genetic Alterations in EGFR Mutated Adenocarcinoma by NGS Analysis: A Multicenter Study Next generation sequencing - Adenocarcinoma of Lung, EGFR Activating Mutation | Unknown | Konkuk University Medical Center | 80 | 2019-09-30 | 2022-08-18 | |
| Mitochondrial Diseases - Long-read Genome and Transcriptome Sequencing in Cases Unresolved After Short-read Genomics Next Generation Sequencing (NGS) - Rare Diseases, Genetic Predisposition | Not applicable | Completed | University Hospital Tuebingen | 20 | 2019-03-01 | 2025-03-30 |
| Cohort Research on Wilson's Disease Next generation sequencing, Imaging and fluid biomarkers - Wilson's Disease | Unknown | University College, London | 500 | 2018-12-06 | 2019-12-26 | |
| A Study of Personalized Neoantigen Cancer Vaccines Blood collection for research (next-generation sequencing [NGS]), Blood collection for research (HLA typing) - Non Small Cell Lung Cancer, Colorectal Cancer | Completed | Gritstone bio, Inc. | 93 | 2018-07-25 | 2020-09-11 | |
| Cell-free DNA in Hereditary And High-Risk Malignancies 1 Next generation sequencing (NGS) - Hereditary Cancer Syndrome | Active not recruiting | University Health Network, Toronto | 1416 | 2018-07-01 | 2026-01-14 |
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Neoplasms (5) · Colorectal Neoplasms (3) · Colorectal Neoplasms, Hereditary Nonpolyposis (3) · Rare Diseases (3) · Breast Neoplasms (2) · Carcinoma, Non-Small-Cell Lung (2) · Diabetes Mellitus, Type 2 (2) · Genetic Predisposition to Disease (2) · Mason-Type Diabetes (2) · Recurrence (2) · Sarcoma (2) · Adenocarcinoma of Lung (1) · Autistic Disorder (1) · Autoimmune Diseases (1) · Biliary Tract Neoplasms (1)
Imperial College London Diabetes Centre (3) · Centre Hospitalier Universitaire Dijon (2) · Gritstone bio, Inc. (2) · Hellenic Cooperative Oncology Group (2) · Institut National de la Santé Et de la Recherche Médicale, France (2) · Second Affiliated Hospital, Zhejiang University, School of Medicine (2) · University Hospital Tuebingen (2) · Australian & New Zealand Children's Haematology/Oncology Group (1) · BAIYONG SHEN (1) · Banaras Hindu University (1) · Brigham and Women's Hospital (1) · CHU de Reims (1) · Centre Henri Becquerel (1) · Dr. Asma Abdus Salam (1) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1)
France (9) · United States (6) · China (5) · United Arab Emirates (3) · Germany (2) · Italy (2) · South Korea (2) · United Kingdom (2) · Australia (1) · Canada (1) · Greece (1) · Hong Kong (1) · India (1) · New Zealand (1) · Pakistan (1)
Maha Barakat, PhD FRCP (2) · Antoine Italiano (1) · David Ziegler (1) · Fabrice Jardin, Professor (1) · Giovanni Martinelli, Prof. (1) · Haitao Wang (1) · In Ae Kim, MD. Ph.D (1) · Jean Mosser, PUPH (1) · Jiayuan Sun, MD,PhD (1) · Jochen D Muehlschlegel, MD MMSc, MBA (1) · John M Maris, MD (1) · Koen van Besien, MD, PhD (1) · Li-Tzong Chen, MD (1) · Manoj Pandey, MS, PhD (1) · Ming-Huang Chen, MD, PhD (1)
PMID 32713836, PMID 26883583, PMID 28139240, PMID 28409480, PMID 28842786, PMID 31775759, PMID 33539543, PMID 34740331, PMID 36291375, PMID 37026827
2017 (1)