12 completed, 5 recruiting, 4 not yet recruiting, 2 terminated. 26 Phase 1, 6 Phase 2.
Follow Ankylosis: new trials by email Literature Review of Ankylosis trials Research Report on Ankylosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase Ia Study of MST-931 in Healthy Adult Subjects MST-931, MST-931 Placebo - Ankylosing Spondylitis (AS) | Phase 1 | Recruiting | Mabsoft Therapeutics (Shanghai) Co., Ltd. | 32 | 2026-11-30 | 2026-11-03 |
| A Study of GKL-006Allo Injection in Patients With Ankylosing Spondylitis GKL-006Allo - Ankylosing Spondylitis | Phase 1 | Not yet recruiting | Beijing Gene Key Life Technology Co., Ltd | 12 | 2026-11-01 | 2026-11-04 |
| Safety and Efficacy of Allogeneic Bone Marrow MSCs in Ankylosing Spondylitis IV administration of CG-BM1, Placebo, CG-BM1 - Ankylosing Spondylitis | Phase 1 | Not yet recruiting | Eighth Affiliated Hospital, Sun Yat-sen University | 40 | 2026-07-01 | 2026-06-08 |
| A Phase I/Ⅱ Clinical Trial for Umbilical Cord Mesenchymal Stem Cells (UC-MSC) in the Treatment of Ankylosing Spondylitis HS_SW01 cells injection - Ankylosing Spondylitis | Phase 1 / Phase 2 | Not yet recruiting | Shenzhen Huishan Biotechnology Co., Ltd. | 18 | 2026-04-10 | 2026-04-20 |
| A Study of HB0017 Injection in Healthy Volunteers to Evaluate Safety and Tolerability of a Single Subcutaneous Injection in Low-Body-Weight Subjects; and Pharmacokinetics at Different Subcutaneous Injection Sites at the Same Dose HB0017 Injection, HB0017 Placebo - Psoriasis, Ankylosing Spondylitis | Phase 1 | Recruiting | Huabo Biopharm Co., Ltd. | 90 | 2026-01-19 | 2026-11-06 |
| A Study to Learn if Bimekizumab Given in Different Ways is Safe and Moves Similarly Throughout the Body Over Time in Adults Bimekizumab regimen 1 iv, Bimekizumab regimen 2 iv, Bimekizumab regimen 3 sc - Psoriatic Arthritis, Axial Spondyloarthritis | Phase 1 | Recruiting | UCB Biopharma SRL | 392 | 2025-12-10 | 2026-11-06 |
| A Study to Assess the Concentration of Bimekizumab in Mature Breast Milk From Mothers Receiving Treatment With Bimzelx® (Bimekizumab) Bimekizumab - Moderate to Severe Plaque Psoriasis, Psoriatic Arthritis | Phase 1 | Recruiting | UCB Biopharma SRL | 20 | 2025-11-05 | 2026-09-18 |
| EAST-1 (ERAP-inhibition in Axial Spondyloarthritis Trial - 1) Part A - Single Ascending Dose (SAD) in Healthy Human Volunteers, Part B - Multiple Ascending Dose (MAD) in participants with axSpA, Part C - Safety expansion cohort in participants with axSpA - Axial Spondyloarthritis (AxSpA) | Phase 1 / Phase 2 | Recruiting | Grey Wolf Therapeutics | 140 | 2025-07-28 | 2026-11-12 |
| Mesenchymal Stem Cells Infusion in Patients With Autoimmune Diseases Mesenchymal Stem Cells, Placebo - Rheumatoid Arthritis, Systemic Lupus Erythematosus (SLE) | Phase 1 / Phase 2 | Enrolling by invitation | National Institute of Blood and Marrow Transplant (NIBMT), Pakistan | 200 | 2025-02-01 | 2025-03-21 |
| Safety and Tolerance of Umbilical Cord Mesenchymal Stem Cells (UC-MSC) in Patients With Ankylosing Spondylitis Human Umbilical Cord Mesenchymal Stem Cells - Ankylosing Spondylitis | Phase 1 | Not yet recruiting | Asia Cell Therapeutics (Shanghai) Co., Ltd. | 9 | 2023-08-30 | 2023-08-15 |
| A Clinical Study With Adalimumab Biosimilar Humira® (adalimumab) AC Pen [Reference Product], Adalimumab Richmond [Test Product] - Pharmacokinetics, Safety Issues | Phase 1 | Completed | Laboratorios Richmond S.A.C.I.F. | 150 | 2022-08-01 | 2024-03-04 |
| A Study in Pregnant Women With Chronic Inflammatory Diseases Treated With Cimzia (Certolizumab Pegol) Pharmacokinetics of certolizumab pegol - Rheumatoid Arthritis, Psoriatic Arthritis | Phase 1 | Completed | UCB Biopharma SRL | 22 | 2020-06-19 | 2024-09-19 |
| Ketorolac vs Oxycodone for Great Toe Arthrodesis Oxycodone, Ketorolac - Arthrodesis | Phase 1 | Unknown | Medstar Health Research Institute | 40 | 2020-04-14 | 2023-07-12 |
| Phase 1 Study With KIN-1901 in Healthy Subjects and Subjects With Ankylosing Spondylitis KIN-1901, Placebo - Inflammation, Rheumatic Diseases | Phase 1 | Completed | Kinevant Sciences GmbH | 36 | 2019-11-12 | 2020-04-13 |
| Comparison of PK and Tolerability of MSB11022 Administered by AI or PFS 40 mg MSB11022 - Rheumatoid Arthritis, Polyarticular Juvenile Idiopathic Arthritis | Phase 1 | Completed | Fresenius Kabi SwissBioSim GmbH | 216 | 2019-07-15 | 2020-03-25 |
| Safety, Tolerability and PK of SHR1314 in axSpA SHR-1314 - Axial Spondyloarthritis | Phase 1 | Completed | Jiangsu HengRui Medicine Co., Ltd. | 45 | 2018-04-19 | 2021-01-13 |
| A Study of Experimental Medication BMS-986251, Taken by Mouth, in Healthy Participants and Patients With Average to Very Serious Psoriasis BMS-986251, Placebo - Rheumatoid Arthritis, Psoriasis | Phase 1 / Phase 2 | Terminated | Bristol-Myers Squibb | 38 | 2017-11-02 | 2019-10-21 |
| Comparative Evaluation of Pharmacokinetics and Safety of BCD-055 and Remicade in Patients With Ankylosing Spondylitis Infliximab (BCD-055), Infliximab (Remicade) - Ankylosing Spondylitis | Phase 1 | Completed | Biocad | 90 | 2015-02-01 | 2016-06-08 |
| 99mTc-rhAnnexin V-128 a Phase I/IIa Study in Patients With Rheumatoid Arthritis (RA) or Ankylosing Spondylitis (AS) 99mTc-rhAnnexin V-128 - Rheumatoid Arthritis, Ankylosing Spondylitis | Phase 1 / Phase 2 | Terminated | Advanced Accelerator Applications | 16 | 2014-12-11 | 2020-10-08 |
| A Multicenter, Postmarketing Study Evaluating the Concentration of Cimzia® in Mature Breast Milk of Lactating Mothers Breast milk sampling, Certolizumab Pegol - Axial Spondyloarthritis (AxSpA), Non-radiographic Evidence-AxSpA | Phase 1 | Completed | UCB BIOSCIENCES, Inc. | 17 | 2014-09-01 | 2018-04-03 |
Showing 20 of 26. Sign in to see all of them.
Spondylitis, Ankylosing (20) · Arthritis, Rheumatoid (9) · Arthritis, Psoriatic (8) · Axial Spondyloarthritis (7) · Crohn Disease (5) · Arthritis, Juvenile (3) · Autoimmune Diseases (3) · Hidradenitis Suppurativa (3) · Colitis, Ulcerative (2) · Psoriasis (2) · Arthritis (1) · Breast Feeding (1) · Dermatomyositis (1) · Inflammation (1)
Joint Diseases (26) · Musculoskeletal Diseases (26) · Bone Diseases (25) · Spinal Diseases (25) · Spondylarthritis (25) · Spondylarthropathies (25) · Spondylitis (25) · Arthritis (24) · Axial Spondyloarthritis (18) · Skin and Connective Tissue Diseases (13) · Skin Diseases (11) · Connective Tissue Diseases (10) · Skin Diseases, Papulosquamous (10) · Immune System Diseases (9)
Infliximab (3) · Certolizumab Pegol (2) · Adalimumab (1) · BCD-055 (1) · Ketorolac (1) · Oxycodone (1) · Sagittal Abdominal Diameter (1) · bimekizumab (1) · gimsilumab (1) · mycophenolic adenine dinucleotide (1)
UCB Biopharma SRL (3) · Celltrion (2) · UCB BIOSCIENCES, Inc. (2) · Advanced Accelerator Applications (1) · Asia Cell Therapeutics (Shanghai) Co., Ltd. (1) · Beijing Gene Key Life Technology Co., Ltd (1) · Biocad (1) · Bristol-Myers Squibb (1) · Eighth Affiliated Hospital, Sun Yat-sen University (1) · Fresenius Kabi SwissBioSim GmbH (1) · Grey Wolf Therapeutics (1) · Huabo Biopharm Co., Ltd. (1) · Jiangsu HengRui Medicine Co., Ltd. (1) · Kinevant Sciences GmbH (1) · Laboratorios Richmond S.A.C.I.F. (1)
United States (8) · China (5) · Netherlands (5) · Switzerland (5) · Germany (4) · Spain (3) · Australia (2) · Canada (2) · France (2) · Poland (2) · South Korea (2) · Argentina (1) · Belarus (1) · Belgium (1) · Bulgaria (1)
Won Park, M.D., Ph.D. (2) · Alison Heald, MD (1) · Chunde Bao (1) · Ethel C. Feleder, MD (1) · Fei Sun, MD (1) · Ivanov Roman, PhD (1) · John Prior, MD, PhD (1) · Memoona Haider, MBBS, FCPS (1) · Radmila Kanceva, MD, PhD (1) · Xin Chang, MD (1) · Ying Wang, PhD (1)
PMID 19587341, PMID 20231202, PMID 26795209, PMID 27117698, PMID 28814432, PMID 29030361, PMID 32905628, PMID 35262901, PMID 42012633
2017 (1), 2025 (1)