11 completed, 6 terminated, 3 active not recruiting, 1 unknown. 22 Phase 2, 6 Phase 1, 3 Phase 3.
Follow Advanced Cancers: new trials by email Literature Review of Advanced Cancers trials Research Report on Advanced Cancers
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Psilocybin in Cancer Pain Study Psilocybin - Opioid-Related Disorders, Pain Management | Phase 2 | Active not recruiting | Yvan Beaussant, MD, MSci | 15 | 2024-09-23 | 2026-10-27 |
| Plasmodium Immunotherapy for Advanced Cancers Blood-stage infection of P.vivax - Advanced Cancers | Phase 1 / Phase 2 | Unknown | CAS Lamvac Biotech Co., Ltd. | 20 | 2017-11-23 | 2024-02-20 |
| A Study of LY2606368 (Prexasertib) in Patients With Solid Tumors With Replicative Stress or Homologous Repair Deficiency LY2606368 - Advanced Cancers | Phase 2 | Completed | Dana-Farber Cancer Institute | 27 | 2016-10-12 | 2022-10-21 |
| Phase II Study of Ilorasertib (ABT348) in Patients With CDKN2A Deficient Solid Tumors Ilorasertib - Advanced Cancers | Phase 2 | Terminated | M.D. Anderson Cancer Center | 12 | 2016-08-05 | 2023-07-17 |
| Sublingual Fentanyl for the Management of Breakthrough Pain Fentanyl Sublingual Spray (FSS), Questionnaires, Mental Ability Tests - Advanced Cancers | Phase 2 | Terminated | M.D. Anderson Cancer Center | 6 | 2016-02-02 | 2021-05-18 |
| Fentanyl Sublingual Spray for Exercise-Induced Breakthrough Dyspnea Fentanyl Sublingual Spray, Shuttle Walk Test, Questionnaires - Advanced Cancers | Phase 2 / Phase 3 | Completed | M.D. Anderson Cancer Center | 50 | 2016-01-04 | 2021-02-09 |
| Fentanyl Buccal Tablets for Exercise Induced Breakthrough Dyspnea Fentanyl Buccal Tablet, Placebo Buccal Tablet, Questionnaires - Advanced Cancers | Phase 2 | Completed | M.D. Anderson Cancer Center | 36 | 2014-05-27 | 2020-09-16 |
| Haloperidol and Lorazepam for Delirium in Patients With Advanced Cancer Lorazepam, Placebo, Haloperidol decanoate - Advanced Cancers | Phase 2 | Active not recruiting | M.D. Anderson Cancer Center | 93 | 2014-01-01 | 2026-07-17 |
| BiPAP-Vapotherm RCT Oxygen Delivery Devices, Questionnaires - Advanced Cancers | Phase 2 | Withdrawn | M.D. Anderson Cancer Center | 2013-12-01 | 2013-08-13 | |
| Aza-SAHA-GBM With AutoSCT for Refractory Lymphoma Azacitidine, Vorinostat, Gemcitabine - Advanced Cancers, Lymphoma | Phase 1 / Phase 2 | Completed | M.D. Anderson Cancer Center | 61 | 2013-11-07 | 2020-01-27 |
| Fentanyl Pectin Nasal Spray (FNPS) for Exercise-Induced Breakthrough Dyspnea Fentanyl Pectin Nasal Spray, Placebo Nasal Spray, Walk Test - Advanced Cancers | Phase 2 | Completed | M.D. Anderson Cancer Center | 35 | 2013-06-11 | 2023-06-08 |
| Dexamethasone Dyspnea Study Dexamethasone, Placebo, Questionnaires - Advanced Cancers, Hematologic Disorder | Phase 2 | Completed | M.D. Anderson Cancer Center | 52 | 2013-01-01 | 2021-02-17 |
| Breakthrough Dyspnea Fentanyl Study in Cancer Patients Fentanyl, Placebo, Walking Tests - Advanced Cancers, Dyspnea | Phase 1 / Phase 2 | Completed | M.D. Anderson Cancer Center | 26 | 2012-04-01 | 2014-08-22 |
| Phase 1/2, Open-label, Dose-escalation Study of IONIS-STAT3Rx, Administered to Patients With Advanced Cancers IONIS-STAT3Rx - Advanced Cancers, DLBCL | Phase 1 / Phase 2 | Completed | Ionis Pharmaceuticals, Inc. | 64 | 2012-02-27 | 2018-06-25 |
| The Effects of Ginseng on Cancer-Related Fatigue Panax Ginseng, Placebo, Questionnaires - Advanced Cancers, Solid Tumors | Phase 1 / Phase 2 | Active not recruiting | M.D. Anderson Cancer Center | 165 | 2011-10-14 | 2026-10-08 |
| The Use of Light Therapy for Managing Sleep Disturbances in Patients With Advanced Cancer Bright Light Therapy, Dim Red Light Therapy, Questionnaires - Advanced Cancers | Phase 2 / Phase 3 | Terminated | M.D. Anderson Cancer Center | 12 | 2011-06-01 | 2019-03-26 |
| Pilot Study of Hyperthermic Peritoneal Perfusion (HIPEC) for Adolescent and Young Adults With Desmoplastic Small Round Cell Tumor Hyperthermic Peritoneal Perfusion (HIPEC), Cisplatin - Advanced Cancers, Sarcoma | Phase 2 | Completed | M.D. Anderson Cancer Center | 22 | 2011-05-09 | 2020-01-13 |
| Fish Oil Versus Statins Versus Placebos in Reducing Atrial Fibrillation in Patients Undergoing Thoracic Surgery for Lung Cancer Atorvastatin, Fish Oil Supplement, Placebo - Advanced Cancers | Phase 2 / Phase 3 | Terminated | M.D. Anderson Cancer Center | 2 | 2011-01-01 | 2012-08-07 |
| High Flow Oxygen and Bilevel Airway Pressure for Persistent Dyspnea in Patients With Advanced Cancer Vapotherm, BIPAP - Advanced Cancers | Phase 2 | Completed | M.D. Anderson Cancer Center | 30 | 2009-08-01 | 2016-03-02 |
| Phosphatidylinositol 3 Kinase and Mammalian Target of Rapamycin (PI3K-mTOR) in Advanced Cancer Patients Temsirolimus - Advanced Cancers | Phase 1 / Phase 2 | Terminated | M.D. Anderson Cancer Center | 44 | 2009-04-01 | 2016-08-25 |
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Dyspnea (6) · Neoplasm Metastasis (3) · Agnosia (2) · Fatigue (2) · Lymphoma (2) · Recurrence (2) · Sarcoma (2) · Anorexia (1) · Anxiety Disorders (1) · Breast Neoplasms (1) · Colorectal Neoplasms (1) · Delirium (1) · Depression (1) · Desmoplastic Small Round Cell Tumor (1) · Fanconi Anemia (1)
Pathological Conditions, Signs and Symptoms (12) · Signs and Symptoms (11) · Neoplasms (8) · Respiratory Tract Diseases (7) · Respiration Disorders (6) · Signs and Symptoms, Respiratory (6) · Hemic and Lymphatic Diseases (5) · Neoplasms by Histologic Type (4) · Nervous System Diseases (4) · Mental Disorders (3) · Neoplasms by Site (3) · Neoplastic Processes (3) · Neurobehavioral Manifestations (3) · Neurologic Manifestations (3) · Pathologic Processes (3)
Surveys and Questionnaires (10) · Calcium Dobesilate (2) · Dexamethasone (2) · Sugars (2) · Asian ginseng (1) · Atorvastatin (1) · Azacitidine (1) · Busulfan (1) · Cisplatin (1) · Fatty Acids, Omega-3 (1) · Fentanyl (1) · Gemcitabine (1) · Glutamine (1) · Health Resources (1) · Hyperthermic Intraperitoneal Chemotherapy (1)
M.D. Anderson Cancer Center (17) · CAS Lamvac Biotech Co., Ltd. (1) · Dana-Farber Cancer Institute (1) · Ionis Pharmaceuticals, Inc. (1) · Merck Sharp & Dohme LLC (1) · Yvan Beaussant, MD, MSci (1)
United States (19) · China (1)
David Hui, MD (8) · Andrea Hayes-Jordan, MD (1) · Ara Vaporciyan, MD, BS (1) · Daniel Karp, MD (1) · David S. Hong, MD (1) · Eduardo Bruera, MD (1) · Geoffrey Shapiro, MD, PhD (1) · Rony Dev, DO (1) · Sriram Yennurajalingam, MD (1) · Steve Hughes, MD (1) · Suresh Reddy, MD (1) · Yago Nieto, MD, PHD (1) · Yvan Beaussant, MD (1)
PMID 21931708, PMID 23739633, PMID 23830530, PMID 27330023, PMID 27401508, PMID 28228842, PMID 28445973, PMID 28650446, PMID 28874596, PMID 28975307, PMID 30446007
R21CA186000 (1)