21 completed. 21 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 21 | Completed 21 |
Follow Adrenocortical Hyperfunction: new trials by email Literature Review of Adrenocortical Hyperfunction trials Research Report on Adrenocortical Hyperfunction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| 68Ga-Pentixafor PET/CT Versus Adrenal Vein Sampling in Primary Aldosteronism: The GAPA Randomized Clinical Trial 68Ga-Pentixafor PET/CT - Primary Aldosteronism | Not applicable | Completed | Chongqing Medical University | 320 | 2024-01-09 | 2026-09-25 |
| Effect of a Proposed Cav1.3 Inhibitor in Primary Aldosteronism Cinnarizine, NIFEdipine ER - Primary Aldosteronism, Endocrine Hypertension | Not applicable | Completed | Queen Mary University of London | 15 | 2023-04-24 | 2024-07-08 |
| [18F]AlF-NOTA-pentixather PET/CT in Patients With Suspected Primary Hyperaldosteronism [18F]AlF-NOTA-pentixather PET/CT - Primary Hyperaldosteronism, Aldosterone-Producing Adenoma | Not applicable | Completed | Sichuan Provincial People's Hospital | 20 | 2023-01-07 | 2026-08-18 |
| AVS After 1mg DST to Determine Subtype in PA Dexamethasone 1 MG Oral Tablet, Placebo - Primary Aldosteronism | Not applicable | Completed | Shanghai Zhongshan Hospital | 110 | 2021-01-08 | 2023-06-01 |
| Corticotropin Stimulation in Adrenal Venous Sampling for Patients With Primary Aldosteronism(ADOPA) Adrenocorticotropic hormone - Primary Aldosteronism | Not applicable | Completed | Chongqing Medical University | 228 | 2020-07-08 | 2023-12-29 |
| Prevalence of Primary Aldosteronism Among Hypertensive Patients With Atrial Arythmia Primary Hyperaldosteronism diagnostic - Primary Aldosteronism, Atrial Fibrillation | Not applicable | Completed | Centre Hospitalier de PAU | 300 | 2020-04-16 | 2023-08-22 |
| Radiofrequency Endoscopic Ablation With Ultrasound Guidance: a Non-surgical Treatment for Aldosterone-producing Adenomas Endoscopic ultrasound guided radiofrequency ablation, ultrasound - Primary Hyperaldosteronism, Primary Hyperaldosteronism Due to Adrenal Adenoma | Not applicable | Completed | University College, London | 28 | 2018-02-21 | 2023-05-12 |
| Determination of Threshold Values of Aldosterone in HPLC-MS/MS, of Renin and of the Aldosterone / Renin Ratio for the Diagnosis of Primary Hyperaldosteronism Aldosterone in HPLC-MS/MS - Hyperaldosteronism; Primary | Not applicable | Completed | University Hospital, Caen | 105 | 2018-01-02 | 2026-06-26 |
| Adrenal Artery Ablation for Primary Aldosteronism With Resistant Hypertension Adrenal Artery Ablation - Resistant Hypertension | Not applicable | Completed | Third Military Medical University | 36 | 2017-10-01 | 2020-04-14 |
| Radiofrequency Ablation for Aldosterone-producting Adenoma in Patients With Primary Aldosteronism Radiofrequency ablation - Primary Aldosteronism, Adrenal Adenoma | Not applicable | Completed | University Hospital, Toulouse | 31 | 2016-11-07 | 2026-05-04 |
| Study of CS-3150 in Patients With Primary Aldosteronism CS-3150 - Primary Aldosteronism | Not applicable | Completed | Daiichi Sankyo Co., Ltd. | 44 | 2016-09-01 | 2018-12-21 |
| Sleep Apnea Diagnosis Using a Novel Pacemaker Algorithm and Link With Aldosterone Plasma Level in Patients Presenting With Diastolic Dysfunction pacemaker diagnostic algorithm, Attended cardiorespiratory sleep study - Sleep Apnea, Arrhythmias, Cardiac | Not applicable | Completed | University Hospital, Caen | 66 | 2016-06-22 | 2026-04-02 |
| Efficacy and Safety of Posterior Retroperitoneoscopic Adrenalectomy: A Comparative Study Posterior retroperitoneoscopic adrenalectomy, Transperitoneal laparoscopic adrenalectomy - Adrenal Mass, Adrenal Disease | Not applicable | Completed | Suez Canal University | 13 | 2015-04-01 | 2017-03-03 |
| Hypercortisolism and Epicardial Adipose Tissue Blood samples for measuring adiponectin, leptin and omentin plasma, MRI at 3 Tesla - Hypercortisolism | Not applicable | Completed | Assistance Publique Hopitaux De Marseille | 43 | 2014-12-08 | 2023-05-26 |
| Primary Hyperaldosteronism and Ischemia-reperfusion Injury forearm ischemia and reperfusion - Primary Hyperaldosteronism | Not applicable | Completed | Radboud University Medical Center | 40 | 2013-11-01 | 2017-10-12 |
| Intraoperative Analysis of Cortisol During Adrenal Vein Sampling Intraoperative cortisol measurement. - Primary Hyperaldosteronism | Not applicable | Completed | Haukeland University Hospital | 21 | 2013-01-01 | 2013-08-29 |
| Comparison Between Posterior Retroperitoneoscopic Adrenalectomy and Laparoscopic Adrenalectomy PRA, LA - Adrenal Disease | Not applicable | Completed | Seoul National University Hospital | 83 | 2012-09-01 | 2017-10-06 |
| In Vivo Study of Interactions Between the Endocannabinoid System and the Corticotropic Axis in Man Obese, Hypercortisolism, Hydrocortisone - Cushing's Syndrome | Not applicable | Completed | University Hospital, Bordeaux | 40 | 2012-02-01 | 2026-05-22 |
| 11C-Metomidate PET Versus Adrenal Vein Sampling in Primary Aldosteronism 11C-Metomidate Positron Emission Tomography - Primary Hyperaldosteronism | Not applicable | Completed | Helsinki University Central Hospital | 40 | 2012-02-01 | 2019-03-11 |
| Etiology of Sleep Apnea-related Hyperaldosteronism - BP Treatment Spironolactone, BP medication uptitration - Obstructive Sleep Apnea, Resistant Hypertension | Not applicable | Completed | University of Alabama at Birmingham | 41 | 2009-01-01 | 2014-01-15 |
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Hyperaldosteronism (17) · Cushing Syndrome (4) · Adrenal Gland Diseases (2) · Adrenocortical Adenoma (2) · Hypertension (2) · Pheochromocytoma (2) · Sleep Apnea Syndromes (2) · ACTH Syndrome, Ectopic (1) · Adrenal incidentaloma (1) · Arrhythmias, Cardiac (1) · Atrial Fibrillation (1) · Bartter Syndrome (1) · Essential Hypertension (1) · Gitelman Syndrome (1) · Hypokalemia (1)
Endocrine System Diseases (21) · Adrenal Gland Diseases (19) · Cardiovascular Diseases (5) · Neoplasms (5) · Pathological Conditions, Signs and Symptoms (3) · Vascular Diseases (3) · Adrenal Cortex Diseases (2) · Adrenal Cortex Neoplasms (2) · Adrenal Gland Neoplasms (2) · Apnea (2) · Dyssomnias (2) · Endocrine Gland Neoplasms (2) · Heart Diseases (2) · Neoplasms by Histologic Type (2)
Adiposity (1) · Adrenocorticotropic Hormone (1) · Aldosterone (1) · Blood Specimen Collection (1) · Cinnarizine (1) · Dexamethasone (1) · Hydrochlorothiazide (1) · Hydrocortisone (1) · Leptin (1) · Liquid Chromatography-Mass Spectrometry (1) · Nifedipine (1) · Radiofrequency Ablation (1) · Reperfusion (1) · Spironolactone (1) · Tablets (1)
Chongqing Medical University (2) · University Hospital, Caen (2) · Assistance Publique Hopitaux De Marseille (1) · Centre Hospitalier de PAU (1) · Daiichi Sankyo Co., Ltd. (1) · Haukeland University Hospital (1) · Helsinki University Central Hospital (1) · Oregon Health and Science University (1) · Queen Mary University of London (1) · Radboud University Medical Center (1) · Seoul National University Hospital (1) · Shanghai Zhongshan Hospital (1) · Sichuan Provincial People's Hospital (1) · Suez Canal University (1) · Third Military Medical University (1)
France (6) · China (5) · United Kingdom (2) · United States (2) · Egypt (1) · Finland (1) · Japan (1) · Netherlands (1) · Norway (1) · South Korea (1)
David H Ellison, MD (1) · Gunnar Mellgren, MD.PhD (1) · Haitham M Badawy, PhD (1) · Kyueun Lee, Ph.D (1) · Morris Brown, MD FRCP (1) · Niina Matikainen, M.D., Ph.D. (1) · Qifu Li, MD, PhD (1) · Qifu Li, PhD (1) · Sami M Shaaban, Professor (1) · Shumin Yang, MD, PhD (1) · Stephen Pereira (1)
PMID 21828936, PMID 26934393, PMID 29279316, PMID 32206838, PMID 15657580, PMID 17161262, PMID 26199389, PMID 27315757, PMID 27325147, PMID 28420172, PMID 28576687, PMID 29129575, PMID 29189215, PMID 29987110, PMID 30042959, PMID 31176302, PMID 32327102, PMID 32890265, PMID 33196558, PMID 36380152, PMID 36795418, PMID 37870836, PMID 39626105, PMID 40052842
R01HL075614 (1)