15 completed, 4 unknown, 1 not yet recruiting, 1 recruiting. 11 Not applicable, 6 Phase 4, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 11 | Completed 7, Unknown 2, Not yet recruiting 1, Terminated 1 |
| Phase 4 | 6 | Completed 5, Recruiting 1 |
| Phase 2 | 1 | Completed 1 |
Follow Acute Diarrhea: new trials by email Literature Review of Acute Diarrhea trials Research Report on Acute Diarrhea
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Saccharomyces Boulardii in Treatment of Acute Diarrhea in Children Aged 6 Months to 5 Years Old Saccharomyces Boulardii Probiotic Supplement, The child will be treated with standard method - Acute Diarrhea | Not applicable | Not yet recruiting | Can Tho University of Medicine and Pharmacy | 206 | 2026-08-31 | 2026-09-10 |
| Rifaximin 200 mg Plus Oral Rehydration vs Oral Rehydration Alone in Children With Acute Diarrhea Rifaximin 200 mg Tablet, Oral Rehydration Therapy (ORT) - Diarrhea, Gastroenteritis | Phase 4 | Recruiting | Bausch Health Americas, Inc. | 54 | 2026-02-11 | 2026-08-13 |
| IL6&8 in Malnourished Children With Acute Diarrhea Evaluation of serum levels of IL-6 and IL-8 - Acute Diarrhea, Severe Acute Malnutrition | Unknown | Sohag University | 60 | 2022-01-01 | 2022-09-21 | |
| Evaluation of Serum Interleukin 6 and 8 in Children With Acute Gastroenteritis Evaluation of serum levels of IL-6 and IL-8 - Acute Gastroenteritis, Acute Diarrhea | Unknown | Sohag University | 60 | 2021-12-15 | 2022-01-28 | |
| Boswellia Serrata Extract in Acute Diarrhea lecithin-based delivery form of Boswellia serrata, Placebo - Acute Diarrhea, Boswellia Serrata | Not applicable | Completed | Azienda di Servizi alla Persona di Pavia | 49 | 2021-03-03 | 2022-04-25 |
| Results of FilmArray® Gastro-intestinal Panel and Serum Procalcitonin in Acute Colitis and Infectious Diarrhea in the ER Filmarray PCR multiplex-PCT assay - Acute Diarrhea, Acute Colitis of Presumed Infectious Origin | Not applicable | Completed | Assistance Publique - Hôpitaux de Paris | 128 | 2020-03-09 | 2022-01-25 |
| Safety, Tolerability and Preliminary Efficacy of Lenodiar Pediatric in Diarrhea Actitan-F (7dd), Actitan-F (28dd) - Diarrhea, Chronic Diarrhea | Not applicable | Unknown | Aboca Spa Societa' Agricola | 240 | 2019-10-01 | 2019-06-04 |
| Zinc Sulfate Acceptability Zinc Sulfate Dispersible Tablet 20 mg (Elemental Zinc 20 mg as Zinc Sulfate Monohydrate / Tablet) - Acute Diarrhea | Not applicable | Completed | International Centre for Diarrhoeal Disease Research, Bangladesh | 325 | 2019-09-09 | 2021-02-05 |
| Improving Nighttime Access to Care and Treatment (Part 2) MotoMeds Healthline- illness assessment and treatment recommendation for non-emergent cases by telephone - Acute Diarrhea, Acute Respiratory Infection | Completed | University of Florida | 391 | 2019-09-09 | 2022-07-20 | |
| Efficacy Of Probiotics vs. Zinc vs. Probiotics-Zinc Combination On Acute Diarrhea In Children Probiotics, Zinc, Probiotics & Zinc - Acute Diarrhea | Not applicable | Completed | Makassed General Hospital | 240 | 2018-10-01 | 2022-08-30 |
| Comparison Of Outcome Of Lactose Free Formula Milk With Yogurt In Children With Acute Diarrhea YOGURT, LACTOSE FREE FORMULA MILK - Acute Diarrhea | Not applicable | Completed | Services Hospital, Lahore | 60 | 2018-06-10 | 2021-03-16 |
| Oral Administration of Tannins and Flavonoids in Children With Acute Diarrhea Actitan F, Standard Oral Rehydration - Acute Diarrhea | Phase 4 | Completed | Federico II University | 60 | 2017-04-01 | 2017-11-29 |
| Probiotics for the Prevention of Antibiotic-Associated Diarrhea Probiotic (BioK+), Placebo - Acute Diarrhea | Not applicable | Terminated | The Hospital for Sick Children | 16 | 2016-11-01 | 2018-04-18 |
| Human Milk Oligosaccharides and Childhood Diarrhoea Oral rehydration solution, Zinc, Human milk oligosaccharides - Acute Diarrhea | Not applicable | Completed | Société des Produits Nestlé (SPN) | 435 | 2016-06-01 | 2019-07-23 |
| Study With Medical Nutrition Product PTM202 in Pediatric Diarrhea PTM202, Placebo - Acute Diarrhea | Not applicable | Completed | PanTheryx, Inc. | 68 | 2013-03-01 | 2013-10-07 |
| Effects of Probiotics and/or Prebiotics on the Duration of Diarrhea and Hospitalization in Children Probiotic, ORS - Acute Diarrhea | Phase 4 | Completed | Eskisehir Osmangazi University | 1280 | 2012-06-01 | 2018-02-05 |
| Efficacy of Racecadotril in Acute Watery Diarrhea in Children Racecadotril, Placebo - Acute Diarrhea, Acute Gastroenteritis | Phase 4 | Completed | Centro Pediatrico Albina de Patino | 52 | 2011-09-01 | 2012-04-13 |
| Efficacy of Use of Zinc in the Treatment of Acute Diarrhea in Infants Zinc Sulfate, placebo - Acute Diarrhea, Acute Gastroenteritis | Phase 4 | Completed | Centro Pediatrico Albina de Patino | 52 | 2011-07-01 | 2013-05-07 |
| Use of Probiotic Yogurt in the Treatment of Acute Diarrhea in Children Probiotic yogurt, Placebo probiotic - Acute Diarrhea, Acute Gastroenteritis | Phase 4 | Completed | Centro Pediatrico Albina de Patino | 54 | 2011-02-01 | 2012-03-27 |
| Cost-effectiveness of Infloran (TM) in Treating Acute Childhood Diarrhea in Phramongkutklao Hospital Probiotic - Infloran - Acute Diarrhea | Not applicable | Unknown | Phramongkutklao College of Medicine and Hospital | 128 | 2010-04-01 | 2011-08-01 |
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Diarrhea (9) · Bacterial Infections (1) · Body Weight (1) · Colitis (1) · Diarrhea, Infantile (1) · Dysentery (1) · Gastroenteritis (1) · Severe Acute Malnutrition (1)
Pathological Conditions, Signs and Symptoms (9) · Signs and Symptoms (9) · Signs and Symptoms, Digestive (9) · Digestive System Diseases (2) · Gastrointestinal Diseases (2) · Bacterial Infections and Mycoses (1) · Colonic Diseases (1) · Gastroenteritis (1) · Infections (1) · Intestinal Diseases (1) · Malnutrition (1) · Nutrition Disorders (1) · Nutritional and Metabolic Diseases (1)
Probiotics (3) · Zinc (3) · ORALIT (2) · Tablets (2) · Zinc Sulfate (2) · Fluid Therapy (1) · Health Maintenance Organizations (1) · Lactation (1) · Rifaximin (1) · Standard of Care (1) · World Health Organization oral rehydration solution (1) · Yogurt (1) · acidocin D20079, Lactobacillus acidophilus (1) · racecadotril (1)
Centro Pediatrico Albina de Patino (3) · Sohag University (2) · Aboca Spa Societa' Agricola (1) · Assistance Publique - Hôpitaux de Paris (1) · Azienda di Servizi alla Persona di Pavia (1) · Bausch Health Americas, Inc. (1) · Can Tho University of Medicine and Pharmacy (1) · Eskisehir Osmangazi University (1) · Federico II University (1) · International Centre for Diarrhoeal Disease Research, Bangladesh (1) · Isfahan University of Medical Sciences (1) · Johann Wolfgang Goethe University Hospital (1) · Makassed General Hospital (1) · PanTheryx, Inc. (1) · Phramongkutklao College of Medicine and Hospital (1)
Bangladesh (3) · Bolivia (3) · Egypt (2) · Italy (2) · Canada (1) · France (1) · Germany (1) · Haiti (1) · Iran (1) · Lebanon (1) · Pakistan (1) · Thailand (1) · Turkey (Türkiye) (1) · United States (1) · Vietnam (1)
Giuseppe Grandy, MD MSc (2) · Abdelrahim A Sadek, MD, PhD (1) · Ali Gholamrezaei, MD (1) · Azharul Islam Khan, PhD, MBBS (1) · Ener C Dinleyici, MD (1) · Eric Nelson, MD PHD (1) · Giuseppe E Grandy, MD MSc (1) · Gordon Guyatt, MD (1) · Jackeline Torrez, MD (1) · Mariam AlAbdullah A Rajab (1) · Nopaorn Phavichitr, MD (1) · Patricia Parkin, MD (1) · Richard M Soria, MD (1) · Richard Soria, MD (1)
PMID 29866147, PMID 33295643, PMID 36528053, PMID 36848897, PMID 38191203
DP5OD019893 (1)