VA Office of Research and Development: Clinical Trials

203 trials sponsored by VA Office of Research and Development, newest first

ClinicalTrials Daily  ·  Areas  ·  Conditions  ·  Drugs  ·  Sponsors  ·  

118 completed, 34 recruiting, 19 terminated, 18 not yet recruiting. 203 Phase 2, 41 Phase 1, 29 Phase 3.

By phase and status

PhaseTrialsStatus
Phase 2203Completed 118, Recruiting 34, Terminated 19, Not yet recruiting 18, Withdrawn 10, Active not recruiting 2, Enrolling by invitation 1, Unknown 1
Phase 141Completed 21, Recruiting 7, Withdrawn 7, Not yet recruiting 4, Terminated 2
Phase 329Completed 23, Recruiting 2, Terminated 2, Active not recruiting 1, Not yet recruiting 1

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Trials (filtered) newest first · largest first

All 203 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Device for Bladder Control for Men With SCI
Noninvasive electrical stimulation device to improve bladder control - Neurogenic Bladder
Phase 1 / Phase 2Not yet recruitingVA Office of Research and Development122028-06-012026-06-25
Testosterone Therapy With or Without Finasteride After Spinal Cord Injury: TRT-SCI Trial
testosterone cypionate, finasteride, placebo injection - Spinal Cord Injury, Spinal Cord Injuries
Phase 2 / Phase 3Not yet recruitingVA Office of Research and Development3002027-10-012026-08-04
Health Coaching and Veteran Reintegration
Health Coaching, Enhanced treatment as usual - Reintegration Into Civilian Life
Phase 2Not yet recruitingVA Office of Research and Development3982027-07-012026-07-24
Written Exposure Therapy Plus Adjunctive Methylphenidate Treatment for Veterans With PTSD
Written Exposure Therapy (WET), methylphenidate (MPH), placebo (PBO) - PTSD - Post Traumatic Stress Disorder
Phase 2Not yet recruitingVA Office of Research and Development1382027-07-012026-10-29
Remotely Administered tDCS to Improve Cognitive Function in Veterans With mTBI and PTSD Principal Investigator
Transcranial direct current stimulation (tDCS), Cognitive training - Cognition, Brain Injuries
Phase 2Not yet recruitingVA Office of Research and Development462027-05-242026-02-17
Duloxetine and aeRobic Exercise to Improve Function in VEterans With Knee Osteoarthritis (DRIVE)
Exercise, Duloxetine, Placebo - Knee Osteoarthritis, Pain
Phase 2Not yet recruitingVA Office of Research and Development1022027-03-012026-06-16
Reducing Firearm Suicide Among Veterans: Evaluating the Effectiveness of Peer-Delivered Lethal Means Counseling
Peer Engagement and Exploration of Responsibility and Safety, Active Control - Suicide, Secure Firearm Storage
Phase 1 / Phase 2Not yet recruitingVA Office of Research and Development1002027-02-012026-10-26
Psilocybin for Depression in Veterans
Psilocybin, modafinil, zolpidem - Major Depression
Phase 2Not yet recruitingVA Office of Research and Development1502027-01-012026-10-26
Immunotherapy Plus Capivasertib for Metastatic Bladder Cancer
capivasertib - Advanced Urothelial Carcinoma
Phase 1 / Phase 2Not yet recruitingVA Office of Research and Development322027-01-012026-10-05
A Clinical Trial of Resistant Potato Starch for Gut MDRO Decolonization
Resistant Potato Starch, Maltodextrin - Clostridium Infections, Methicillin-resistant Staphylococcus Aureus (MRSA)
Phase 2Not yet recruitingVA Office of Research and Development1202027-01-012026-08-28
Allopregnanolone in Chronic Complex Traumatic Brain Injury
Placebo, Allopregnanolone - Traumatic Brain Injury (TBI)
Phase 2Not yet recruitingVA Office of Research and Development1322026-12-012026-10-19
Investigating Novel Interventions for Low Back Pain in US Military Veterans: A Randomized Controlled Adaptive Phase II Trial
Pregnenolone, DHEA, Placebo - Chronic Low Back Pain
Phase 2Not yet recruitingVA Office of Research and Development1082026-12-012026-09-08
Labyrinthin Vaccination in Veterans With Lung Adenocarcinoma
LabVax 3(22)-23 and GM-CSF (adjuvant) in combination with pembrolizumab - Type and Grade of Toxicities, Demographic and Background Characteristics, Advanced, Metastatic, Recurrent Adenocarcinoma and Malignant Solid Neoplasm
Phase 2Not yet recruitingVA Office of Research and Development302026-12-012026-10-06
Retreat-Based Program for Violence-Exposed Women Veterans
GRIT, GRI - Suicide Prevention
Phase 2Not yet recruitingVA Office of Research and Development482026-12-012026-07-31
Tocilizumab Combined With First-Line Chemo-Immunotherapy in Metastatic Non-Small Cell Lung Cancer
Tocilizumab, Pembrolizumab, Platinum-Doublet Chemotherapy - Metastatic Non-Small Cell Lung Cancer, Cancer-Associated Weight Loss
Phase 1 / Phase 2Not yet recruitingVA Office of Research and Development432026-11-012026-10-30
Microbiota trAnSplant ThERaPy In hEpatiC Encephalopathy (MASTERPIECE)
Microbiota transplant therapy (MTT) capsules, Placebo capsule - Hepatic Encephalopathy, Cirrhosis
Phase 2Not yet recruitingVA Office of Research and Development1622026-10-302026-04-14
Vascular Effects of SGLT2i in Non-diabetic CKD
Empagliflozin, Placebo - Non-diabetic Chronic Kidney Disease
Phase 2Not yet recruitingVA Office of Research and Development522026-10-012026-08-20
LOw DosE Spironolactone, chlorThAlidone oR Combination in CKD Trial
phase 2A Chlorthalidone, phase 2A Spironolactone, phase 2A Chlorthalidone + Spironolactone - Hypertension Treated With Antihypertensive Drugs, Chronic Kidney Disease, 3B and 4
Phase 2Not yet recruitingVA Office of Research and Development1602026-10-012026-06-12
Focused Ultrasound for PTSD in Veterans
Brainsonix Ultrasound Device - Posttraumatic Stress Disorder
Phase 2RecruitingVA Office of Research and Development602026-09-092026-09-15
MDMA-Assisted Therapy for Veterans With PTSD and Alcohol Use Disorder
Full Dose MDMA, MDMA-Assisted psychotherapy, Active Placebo Dose MDMA - Post Traumatic Stress Disorder, Alcohol Use Disorder
Phase 2 / Phase 3RecruitingVA Office of Research and Development802026-05-182026-06-02

Showing 20 of 203. Sign in to see all of them.

Conditions studied

Stress Disorders, Post-Traumatic (30)  ·  Spinal Cord Injuries (13)  ·  Motor Activity (10)  ·  Alcoholism (9)  ·  Depression (9)  ·  Prostatic Neoplasms (8)  ·  Sleep Apnea Syndromes (8)  ·  Stroke (8)  ·  Multiple Sclerosis (7)  ·  Schizophrenia (7)  ·  Renal Insufficiency, Chronic (6)  ·  Tobacco Use Disorder (6)  ·  Carcinoma, Non-Small-Cell Lung (5)  ·  Cardiovascular Diseases (5)  ·  Diabetes Mellitus (5)

Interventions

Ketamine (6)  ·  Pregnenolone (5)  ·  Oxytocin (4)  ·  Sodium Chloride (4)  ·  Sugars (4)  ·  Testosterone (4)  ·  pembrolizumab (4)  ·  Cholecalciferol (3)  ·  Cognitive Behavioral Therapy (3)  ·  Finasteride (3)  ·  Midazolam (3)  ·  Naltrexone (3)  ·  3-(2,4-dimethoxybenzylidene)anabaseine (2)  ·  Abiraterone Acetate (2)  ·  Acetylcysteine (2)

Countries

United States (203)  ·  Canada (1)

Top investigators

Christine E. Marx, MD MA (4)  ·  Ashraf Gorgey, PhD PT (3)  ·  Carl J Stepnowsky, PhD (3)  ·  Jennifer C Naylor, PhD (3)  ·  Nasia Safdar, MD PhD (3)  ·  Adriana M Hung, MD MPH (2)  ·  Amy A Herrold, PhD BA (2)  ·  Chong-Xian Pan, MD PhD (2)  ·  Christine Marx, MD MA (2)  ·  Gihyun Yoon, MD (2)  ·  Jasmohan S. Bajaj, MD MS (2)  ·  Joshua F Yarrow, PhD MS BS (2)  ·  Matthew B. Rettig, MD (2)  ·  Nicholas George Nickols, MD PhD (2)  ·  Nithya Ramnath, MD (2)

Results publications

PMID 11483142, PMID 12823166, PMID 15126771, PMID 15870612, PMID 16095473, PMID 16131943, PMID 16571581, PMID 16680620, PMID 16737798, PMID 17441783, PMID 17513285, PMID 17690799, PMID 18295436, PMID 18381905, PMID 18461049, PMID 19122865, PMID 20012639, PMID 20012982, PMID 20598832, PMID 20619405, PMID 20728875, PMID 20739168, PMID 20853931, PMID 21252493, PMID 21517712, PMID 21679267, PMID 21717386, PMID 21791356, PMID 21815915, PMID 21840138, PMID 21846661, PMID 21885958, PMID 22300564, PMID 22334806, PMID 22406052, PMID 22578037, PMID 22763197, PMID 22836351, PMID 22968110, PMID 23327503, PMID 23333585, PMID 23343764, PMID 23370525, PMID 23696427, PMID 23804455, PMID 24012740, PMID 24090622, PMID 24223036, PMID 24326421, PMID 24458967

NIH funding

R21AT004490 (2), 1IK2CX000547 (1), 1IK2CX000946-01 (1), 1IK2CX001397-01A2 (1), 1IK2CX001495-01 (1), 1IK2CX002225-01A1 (1), 1IK2CX002877-01A1 (1), 1IK2RD000464-01A2 (1), 1IK2RX001136-01A2 (1), 1IK2RX001180-01A2 (1), I01CX000264 (1), I01CX000569 (1), I01CX000982 (1), I01CX001414 (1), I01CX001761 (1)