15 completed, 4 terminated, 3 recruiting, 3 unknown. 30 Phase 2, 5 Phase 1, 3 Phase 3.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Magnesium Supplementation in Advanced Non-small Cell Lung Cancer (NSCLC) Magnesiocard, Magnesium Diasporal, Microcrystalline cellulose - Metastatic NSCLC - Non-Small Cell Lung Cancer | Phase 2 / Phase 3 | Recruiting | Swiss Cancer Institute | 230 | 2026-09-29 | 2026-10-28 |
| Glucose Tolerance Study TRPTI 150mg, TRPTI 300mg, Placebo - Healthy Volunteers, Glucose Tolerance | Phase 2 | Completed | RDC Clinical Pty Ltd | 19 | 2026-03-11 | 2026-04-28 |
| A Randomized Neuroimaging Trial of Psilocybin in Depression Psilocybin, Microcrystalline cellulose, Supportive psychotherapy - Depressive Disorder, Major Depressive Disorder | Phase 2 | Recruiting | Sunnybrook Health Sciences Centre | 50 | 2025-05-28 | 2026-03-30 |
| Nicotinic Acid for the Treatment of Alzheimer's Disease Placebo Comparator, Extended Release Niacin - Alzheimer Disease | Phase 1 / Phase 2 | Recruiting | Indiana University | 30 | 2024-12-19 | 2026-03-05 |
| Reducing Frailty for Older Cancer Survivors Using Supplements II Epigallocatechin-3-Gallate (EGCG), Microcrystalline cellulose (MCC), Ascorbic Acid (Vitamin C) - Frailty, Inflammation | Phase 2 | Suspended | University of Rochester | 118 | 2024-10-25 | 2026-06-26 |
| Exploring Treatments for Children's Abdominal Pain: Comparing Trimebutine and Probiotics Trimebutine, Lactobacillus rhamnosus, Placebo - Functional Abdominal Pain Syndrome, Functional Gastrointestinal Disorders | Phase 1 / Phase 2 | Unknown | Universidad de Colima | 82 | 2024-09-01 | 2024-08-16 |
| Clavulanic Acid for the Treatment of Cocaine Use Disorder Clavulanic Acid Only Product, Placebo - Cocaine Dependence | Phase 2 | Active not recruiting | Temple University | 65 | 2023-05-03 | 2024-05-02 |
| Noise-Induced Hearing Loss-Acute Exposure Treatment (UA) Zonisamide 100Mg Cap, Placebo - Hearing Loss, Noise-Induced | Phase 2 | Terminated | Washington University School of Medicine | 3 | 2021-11-10 | 2026-02-13 |
| The Utility of Camostat Mesylate in Patients With COVID-19 Associated Coagulopathy (CAC) and Cardiovascular Complications Camostat Mesylate, Microcrystalline Cellulose, NF - Coagulopathy, Cardiovascular Complication | Phase 1 / Phase 2 | Withdrawn | Yale University | 2021-11-01 | 2022-05-18 | |
| Noise-Induced Hearing Loss-Acute Exposure Treatment Zonisamide 100Mg Cap, Placebo - Hearing Loss, Noise-Induced | Phase 2 | Terminated | Washington University School of Medicine | 24 | 2021-10-04 | 2025-01-15 |
| Nicotinamide Riboside in SARS-CoV-2 (COVID-19) Patients for Renal Protection Placebo, Nicotinamide riboside - SARS-CoV-2 Infection, Acute Kidney Injury | Phase 2 | Completed | The University of Texas Health Science Center at San Antonio | 28 | 2021-06-11 | 2023-12-26 |
| Dose-Ranging Study to Assess the Safety and Efficacy of Melatonin in Outpatients Infected With COVID-19 Melatonin, Placebo - COVID-19 | Phase 2 | Withdrawn | State University of New York at Buffalo | 2021-04-01 | 2022-07-22 | |
| A Study of Oral Ibogaine in Opioid Withdrawal DMX-1002, Placebo - Opiate Withdrawal Syndrome | Phase 1 / Phase 2 | Completed | atai Therapeutics, Inc. | 116 | 2021-04-01 | 2024-08-06 |
| Lamotrigine and Bupropion for Meniere's Disease Lamotrigine and Bupropion, Placebo - Meniere Disease, Ménière's Vertigo | Phase 2 | Unknown | Dent Neuroscience Research Center | 34 | 2020-12-16 | 2022-06-21 |
| KAND567 Versus Placebo in Subjects Hospitalized With COVID-19 KAND567, Microcrystalline cellulose - Covid19 | Phase 2 | Terminated | Novakand Pharma AB | 35 | 2020-10-11 | 2023-08-25 |
| The Exercise Response to Pharmacologic Cholinergic Stimulation in Myalgic Encephalomyelitis / Chronic Fatigue Syndrome Pyridostigmine Bromide, Placebo - Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, Chronic Fatigue Syndrome | Phase 2 | Completed | Brigham and Women's Hospital | 45 | 2020-01-14 | 2022-11-08 |
| Curcumin and Function in Older Adults Curcumin, microcrystalline cellulose - Older Adults, Physical Function | Phase 2 / Phase 3 | Completed | University of Florida | 17 | 2017-08-11 | 2022-07-26 |
| Ramelteon in the Prevention of Post-operative Delirium Ramelteon, Microcrystalline Cellulose, Riboflavin 100 mg - Delirium, Delirium, Dementia, Amnestic, Cognitive Disorders | Phase 2 | Completed | Johns Hopkins University | 80 | 2017-03-24 | 2020-06-30 |
| Efficacy and Safety of 4-aminopyridine on Cognitive Performance and Motor Function of Patients With Multiple Sclerosis 4-aminopyridine, Placebo - Multiple Sclerosis | Phase 2 | Completed | Coordinación de Investigación en Salud, Mexico | 24 | 2014-10-01 | 2019-09-12 |
| Study of Lamotrigine to Treat Ménière's Disease Lamotrigine, Placebo - Meniere's Disease, Ménière's Vertigo | Phase 2 | Completed | Dent Neuroscience Research Center | 15 | 2014-06-01 | 2022-06-22 |
Showing 20 of 30. Sign in to see all of them.
COVID-19 (4) · Dizziness (2) · Hearing Loss, Noise-Induced (2) · Inflammation (2) · Insulin Resistance (2) · Meniere Disease (2) · Opioid-Related Disorders (2) · Vertigo (2) · Vestibular Diseases (2) · Acute Kidney Injury (1) · Alzheimer Disease (1) · Autonomic Nervous System Diseases (1) · Bronchitis (1) · Carcinoma, Non-Small-Cell Lung (1) · Cocaine-Related Disorders (1)
Danisco (3) · Dent Neuroscience Research Center (2) · University of Florida (2) · Washington University School of Medicine (2) · Brigham and Women's Hospital (1) · Columbia University (1) · Coordinación de Investigación en Salud, Mexico (1) · Dong-A Pharmaceutical Co., Ltd. (1) · Hanlim Pharm. Co., Ltd. (1) · Hospital de Egas Moniz (1) · Indiana University (1) · Johns Hopkins University (1) · Novakand Pharma AB (1) · RDC Clinical Pty Ltd (1) · State University of New York at Buffalo (1)
United States (15) · Finland (3) · Mexico (2) · South Korea (2) · Australia (1) · Canada (1) · Denmark (1) · Portugal (1) · Sweden (1) · Switzerland (1) · United Kingdom (1)
Craig A Buchman, MD, FACS (2) · Lixin Zhang, MD, PhD (2) · Aila Rissanen, MD (1) · Alison Oliveto, PhD (1) · Anne Lithonius (1) · Anneli Tarpila, PhD (1) · Arya Mani, MD (1) · Bradley J MacIntosh, PhD (1) · Christoph Hess, Prof MD, PhD (1) · Claudia Arreola Mora, MS (1) · Claudia Carvalho, PhD (1) · David Systrom, MD (1) · Israel Grijalva, PhD (1)
PMID 26543027, PMID 27810310, PMID 29078780, PMID 30525950, PMID 30593980, PMID 32283645, PMID 32532654, PMID 33281447, PMID 35526605, PMID 38956594
P30AG028740 (2), 3UH3DK114920-04S2 (1), P50NS049060 (1), R21AG050850 (1), R21DA035325 (1), UL1TR001412 (1)