23 completed, 7 unknown, 4 recruiting, 3 not yet recruiting. 15 Not applicable, 12 Phase 2, 6 Phase 1, 1 Early Phase 1, 1 Phase 3.
Follow Hearing Loss, Noise-Induced: new trials by email Literature Review of Hearing Loss, Noise-Induced trials Research Report on Hearing Loss, Noise-Induced
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intervention for Hearing Health Among Native Americans Talking Circle, Diabetes prevention program & delayed TC - Noise-Induced Hearing Loss | Not applicable | Not yet recruiting | University of California, San Francisco | 400 | 2027-04-01 | 2026-08-21 |
| A Multilevel Intervention to Prevent Noise Exposure in Farmworkers Multilevel Hearing Protection Training - Noise Exposure, Hearing Loss, Noise-Induced | Not applicable | Not yet recruiting | San Diego State University | 200 | 2026-10-01 | 2026-04-28 |
| OCCUPATIONAL NOISE AND CHEMICAL EXPOSURE EFFECTS ON AUDITORY AND VESTIBULAR FUNCTION Occupational Noise Exposure | Not yet recruiting | Ondokuz Mayıs University | 50 | 2026-09-03 | 2026-09-08 | |
| Comparative Efficacy of Earplug Usage Instruction Video-Based Earplug Instruction, Paper-Based Earplug Instruction - Noise-Induced Hearing Loss, Hearing Protection Device Use | Not applicable | Enrolling by invitation | Sirinthorn Chanaveroj | 64 | 2026-06-08 | 2026-07-28 |
| A Phase 2b Study of SPI-1005 to Prevent Acute Noise Induced Hearing Loss SPI-1005 200mg, SPI-1005 400mg, Placebo - Noise Induced Hearing Loss | Phase 2 | Withdrawn | Sound Pharmaceuticals, Incorporated | 2026-06-01 | 2026-06-03 | |
| Prevention of Noise-Induced Hearing Loss in Primary Education HoorToren educational package - Effectiveness of Application Education Intervention, Noise Induced Hearing Loss | Not applicable | Recruiting | Erasmus Medical Center | 600 | 2026-03-30 | 2026-04-06 |
| Regenerative Medicine and Stem Cell-Based Interventions for Inner Ear Trauma, Tinnitus, and Sensorineural Hearing Loss Audiologic Monitoring, Investigational Regenerative Pharmacologic Therapy, Stem Cell Regenerative Therapy - Sensorineural Hearing Loss, Tinnitus | Early Phase 1 | Enrolling by invitation | Truway Health, Inc. | 120 | 2026-03-08 | 2026-03-16 |
| Hearing/ET/Vestibular in Balloon Pilots Non-invasive audiologic and vestibular assessments - Hearing Loss, Noise-Induced, Eustachian Tube Dysfunction | Completed | Gaziosmanpasa Research and Education Hospital | 105 | 2025-09-04 | 2026-01-21 | |
| A Treatment for a Form of Age-Related Central Auditory Processing Disorder Consisting of Clemastine Fumarate Plus Engineered Sound Clemastine Fumarate Combined With Engineered Sound, Clemastine Fumarate Combined With Pink Noise, Placebo Drug With Engineered Sound - Central Auditory Processing Disorder, Hearing Impaired (Partially) | Phase 1 / Phase 2 | Recruiting | University of Colorado, Denver | 344 | 2025-03-31 | 2026-04-30 |
| Non-Invasive System to Deliver Therapeutic Hypothermia for Protection Against Noise-Induced Hearing Loss Cold pack-delivered mild therapeutic hypothermia - Noise Exposure, Noise-induced Hearing Loss | Not applicable | Recruiting | Restorear Devices LLC | 116 | 2024-12-19 | 2026-07-23 |
| Preschool Hearing Screening Otoacoustic Emissions Testing, Pure Tone Audiometry - Hearing Loss, Hearing Disorders in Children | Not applicable | Recruiting | University of California, San Francisco | 13764 | 2023-10-01 | 2026-02-02 |
| Three-dimensional Perception of Sounds in Military with Acoustic Trauma SPHERE protocol : Spatial hearing performances test, French Matrix Test : audiology test of speech in noise perception, SSQ15 questionnaire of life : (The Speech, Spatial and Other Qualities of Hearing Scale) - Hearing Loss | Unknown | Hospices Civils de Lyon | 46 | 2023-03-31 | 2024-09-25 | |
| Determination of the Effects of Noise Level in the Operating Room No intervention - Noise; Adverse Effect, Noise Induced Hearing Loss | Unknown | Baskent University | 500 | 2022-12-01 | 2022-12-05 | |
| The Effect of Acupuncture on Patients With Noise-induced Hearing Loss electroacupuncture - Electroacupuncture, Noise Induced Hearing Loss | Not applicable | Unknown | China Medical University Hospital | 80 | 2022-09-01 | 2022-08-23 |
| Understanding the Consequences of Recreational Noise Exposure Hearing Loss, Hearing Loss, Noise-Induced | Completed | University of Nottingham | 200 | 2022-05-19 | 2025-07-09 | |
| Noise-Induced Hearing Loss-Acute Exposure Treatment (UA) Zonisamide 100Mg Cap, Placebo - Hearing Loss, Noise-Induced | Phase 2 | Terminated | Washington University School of Medicine | 3 | 2021-11-10 | 2026-02-13 |
| FX-322 in Adults With Acquired Sensorineural Hearing Loss FX-322, Placebo - Hearing Loss, Sensorineural, Noise Induced Hearing Loss | Phase 2 | Completed | Frequency Therapeutics | 142 | 2021-10-12 | 2023-04-21 |
| Noise-Induced Hearing Loss-Acute Exposure Treatment Zonisamide 100Mg Cap, Placebo - Hearing Loss, Noise-Induced | Phase 2 | Terminated | Washington University School of Medicine | 24 | 2021-10-04 | 2025-01-15 |
| Verification of the Efficacy/safety of the Intratympanic Drug Delivery for Hearing Loss Dexamethasone, Hyaluronic acid - Hearing Loss, Sudden, Hearing Loss, Ototoxic | Phase 1 / Phase 2 | Completed | Seoul National University Hospital | 15 | 2021-07-22 | 2024-10-24 |
| Study of Diagnostic Biomarkers of Acute Acoustic Trauma Hearing test, Questionnaire about previous noise exposure, Otoacoustic emission measurement - Acoustic Trauma | Unknown | Direction Centrale du Service de Santé des Armées | 500 | 2021-04-15 | 2022-11-17 |
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Hearing Loss (15) · Hearing Loss, Sensorineural (9) · Tinnitus (9) · Hearing Loss, Sudden (7) · Hearing Loss, Hidden (2) · Presbycusis (2) · Attention Deficit Disorder with Hyperactivity (1) · Auditory Diseases, Central (1) · Bronchiolitis Obliterans Syndrome (1) · Hearing Disorders (1) · Hearing Loss, Bilateral (1) · Hearing Loss, Conductive (1) · Hearing Loss, Mixed Conductive-Sensorineural (1) · Hearing Loss, Unilateral (1)
Ear Diseases (45) · Nervous System Diseases (45) · Neurologic Manifestations (45) · Otorhinolaryngologic Diseases (45) · Pathological Conditions, Signs and Symptoms (45) · Sensation Disorders (45) · Signs and Symptoms (45) · Hearing Disorders (44) · Hearing Loss, Sensorineural (36) · Hearing Loss (30) · Retrocochlear Diseases (2) · Attention Deficit and Disruptive Behavior Disorders (1) · Brain Diseases (1) · Bronchial Diseases (1) · Bronchiolitis (1)
Zonisamide (3) · Capsules (2) · Hearing (2) · microcrystalline cellulose (2) · Acetylcysteine (1) · Clemastine (1) · Contraceptives, Oral (1) · D-JNKI-1 (1) · Dexamethasone (1) · Electroacupuncture (1) · Gabapentin (1) · Hyaluronic Acid (1) · Magnesium (1) · Methylprednisolone (1) · Methylprednisolone Acetate (1)
Frequency Therapeutics (4) · Washington University School of Medicine (3) · Direction Centrale du Service de Santé des Armées (2) · University of California, San Francisco (2) · University of Michigan (2) · Apple Inc. (1) · Assuta Medical Center (1) · Auris Medical AG (1) · Baskent University (1) · Chang Gung Memorial Hospital (1) · China Medical University Hospital (1) · Edison Pharmaceuticals Inc (1) · Erasmus Medical Center (1) · Faculdade de Medicina de Valenca (1) · Gaziosmanpasa Research and Education Hospital (1)
United States (24) · France (3) · United Kingdom (3) · Israel (2) · Turkey (Türkiye) (2) · Belgium (1) · Brazil (1) · Croatia (1) · Germany (1) · Netherlands (1) · South Korea (1) · Thailand (1)
Carl LeBel, PhD (4) · Craig A Buchman, MD, FACS (2) · Achim Klug, PhD (1) · Andrew Smith, MB ChB (1) · Carol Bauer, MD (1) · Colleen G Le Prell, PhD (1) · Colleen Le Prell, Ph.D (1) · Dylan K Chan, MD, PhD (1) · Emily Frost (1) · Gabrielle H Saunders (1) · Gavin C Solomon, CEO (1)
PMID 21974483, PMID 22122960, PMID 22773265, PMID 24467444, PMID 24708640, PMID 24975234, PMID 25927191, PMID 26475373, PMID 26766172, PMID 34840034, PMID 35364926, PMID 37992408
K23DC022303 (1), R01DC013885 (1), R01NR021182 (1), R44DC018760 (1), U01DC008423 (1)