5 completed. 5 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 5 | Completed 5 |
Follow Yaws: new trials by email Literature Review of Yaws trials Research Report on Yaws
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Repurposing Clinically Approved Drugs for Yaws With an Insight Into the Cutaneous Ulcer Disease Syndrome (Trep-AByaws) Linezolid Oral Tablet, Azithromycin Oral Tablet - Yaws, Cutaneous Ulcer | Phase 3 | Completed | Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia | 383 | 2023-03-14 | 2026-10-22 |
| Safety of Co-administration of IDA and Azithromycin for NTDs ( ComboNTDs ) Albendazole on Day 1, Ivermectin on Day 1, Diethylcarbamazine on day 1 - Trachoma, Yaws | Phase 3 | Completed | Lihir Medical Centre | 20000 | 2018-10-01 | 2019-02-28 |
| Comparison of Two Different Doses of Azithromycin for Treatment of Yaws Azithromycin - Yaws | Phase 3 | Completed | London School of Hygiene and Tropical Medicine | 583 | 2015-06-01 | 2018-10-31 |
| Effect of WHO-yaws Elimination Strategy in Lihir Island, Papua New Guinea Azithromycin - Yaws | Phase 3 | Completed | Lihir Medical Centre | 16000 | 2013-03-01 | 2017-08-28 |
| Single-dose Azithromycin for the Treatment of Yaws Penicillin-G-benzathine, Azithromycin - Yaws, Treponema Infection | Phase 3 | Completed | Lihir Medical Centre | 255 | 2010-09-01 | 2012-04-13 |
Neglected Diseases (2) · Elephantiasis, Filarial (1) · Scabies (1) · Skin Ulcer (1) · Strongyloidiasis (1) · Trachoma (1) · Treponemal Infections (1)
Bacterial Infections (5) · Bacterial Infections and Mycoses (5) · Gram-Negative Bacterial Infections (5) · Infections (5) · Skin Diseases (5) · Skin Diseases, Bacterial (5) · Skin Diseases, Infectious (5) · Skin and Connective Tissue Diseases (5) · Spirochaetales Infections (5) · Treponemal Infections (4) · Disease Attributes (2) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Chlamydia Infections (1) · Chlamydiaceae Infections (1)
Azithromycin (5) · Albendazole (1) · Diethylcarbamazine (1) · Ivermectin (1) · Linezolid (1) · Penicillin G (1) · Penicillin G Benzathine (1)
Lihir Medical Centre (3) · Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia (1) · London School of Hygiene and Tropical Medicine (1)
Papua New Guinea (5) · Ghana (1) · United Kingdom (1)
Camila Beiras (1) · David Mabey (1) · Lucy John, MD (1) · Oriol Mitja, MD, PhD (1) · Quique Bassat, MD, PhD (1)
PMID 22240407, PMID 25693010, PMID 29107621, PMID 29428183, PMID 29456191