6 completed. 6 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 6 | Completed 6 |
Follow Vaso-Occlusive Crises: new trials by email Literature Review of Vaso-Occlusive Crises trials Research Report on Vaso-Occlusive Crises
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| An Indian Multi-centric Phase IV Study to Assess the Safety of Crizanlizumab in Sickle Cell Disease Patients crizanlizumab - Sickle Cell Disease (SCD) | Phase 4 | Completed | Novartis Pharmaceuticals | 140 | 2021-07-14 | 2025-09-26 |
| Low Dose Ketamine and Acute Pain Crisis Ketamine, Normal Saline - Sickle Cell Crisis | Phase 4 | Completed | Rhode Island Hospital | 20 | 2020-07-01 | 2021-12-23 |
| Does IV Acetaminophen Reduce Opioid Requirement in Pediatric Patients With Acute Sickle Cell Crises? Acetaminophen, Normal saline - Sickle Cell Anemia Crisis | Phase 4 | Completed | Newark Beth Israel Medical Center | 71 | 2018-02-20 | 2021-04-02 |
| Low-dose Ketamine vs Morphine for Vaso-occlusive Crisis in Sicklers Low dose ketamine, Morphine - Sickle Cell Crisis, Acute Pain | Phase 4 | Completed | Makerere University | 240 | 2015-06-01 | 2016-08-03 |
| Comparing Acute Pain Management Protocols for Patients With Sickle Cell Disease Hydromorphone (Standardized, weight-based dosing), Morphine Sulfate (Standardized, weight-based dosing), Hydromorphone (Patient Specific dosing) - Sickle Cell Disease | Phase 4 | Completed | Duke University | 106 | 2015-03-15 | 2017-08-04 |
| Intranasal Fentanyl for Initial Treatment of a Vaso-occlusive Crisis Fentanyl Citrate, Normal Saline - Anemia, Sickle Cell, Pain | Phase 4 | Completed | Montefiore Medical Center | 124 | 2011-12-01 | 2016-08-19 |
Anemia, Sickle Cell (3) · Emergencies (2) · Acute Pain (1) · Agnosia (1) · Hemoglobin SC Disease (1) · Pain (1)
Anemia (6) · Anemia, Hemolytic (6) · Anemia, Hemolytic, Congenital (6) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (6) · Genetic Diseases, Inborn (6) · Hematologic Diseases (6) · Hemic and Lymphatic Diseases (6) · Hemoglobinopathies (6) · Pathological Conditions, Signs and Symptoms (4) · Anemia, Sickle Cell (3) · Neurologic Manifestations (3) · Signs and Symptoms (3) · Disease Attributes (2) · Pathologic Processes (2) · Nervous System Diseases (1)
Saline Solution (3) · Ketamine (2) · Morphine (2) · Acetaminophen (1) · Fentanyl (1) · Hydromorphone (1) · Sodium Chloride (1) · crizanlizumab (1)
Duke University (1) · Makerere University (1) · Montefiore Medical Center (1) · Newark Beth Israel Medical Center (1) · Novartis Pharmaceuticals (1) · Rhode Island Hospital (1)
United States (4) · India (1) · Uganda (1)
Cena Tejani, MD (1) · Daniel M Fein, MD (1) · Deogratias Munube, MMed (1) · Felix A. Lubega, MBChB (1) · Fred Bulamba, MBChB (1) · Mithrika S De Silva, MD (1) · Taneisha Wison, MD, ScM (1) · Tonny S. Luggya, MMed (1)