60 completed, 16 unknown, 4 terminated, 3 recruiting. 87 Phase 3, 15 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 87 | Completed 60, Unknown 16, Terminated 4, Recruiting 3, Not yet recruiting 2, Withdrawn 2 |
| Phase 2 | 15 | Completed 7, Unknown 6, Not yet recruiting 1, Recruiting 1 |
Follow Vaginitis: new trials by email Literature Review of Vaginitis trials Research Report on Vaginitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| AUTOP 2: Screen-and-treat Strategy for Vaginal Flora Abnormalities by Molecular Biology in Pregnant Women at High Risk of Preterm Birth Vaginal flora abnormalities screening and quantification using molecular biology technique, Azithromycin, Ceftriaxone - Bacterial Vaginosis, Vaginal Dysbiosis | Phase 3 | Not yet recruiting | Assistance Publique Hopitaux De Marseille | 1794 | 2026-10-01 | 2026-08-27 |
| Study to Evaluate Efficacy and Safety of Gyntima® Balance in Preventing Recurrences of Bacterial Vaginosis Lactobacillus gasseri KABP®064 10e9 CFU/capsule, Placebo (maltodextrin) - Vaginosis, Bacterial, Bacterial Vaginosis | Phase 2 / Phase 3 | Not yet recruiting | Kaneka Americas Holding Inc. | 160 | 2026-04-01 | 2026-04-14 |
| Safety and Efficacy of Boric Acid Inserts for Treatment of Vulvovaginal Candidiasis Boric acid, Placebo - Vulvovaginal Candidiases, Vulvovaginal Candidiasis, Genital | Phase 3 | Completed | pH-D Feminine Health LLC | 333 | 2025-08-08 | 2026-10-23 |
| Efficacy and Safety of Vaginal Lactobacillus Dual Probiotic Capsules in Bacterial Vaginosis Vaginal Lactobacillus Dual Probiotic Capsules, Placebo - Bacterial Vaginosis (BV) | Phase 3 | Completed | Guangdong Longchuangji Pharmaceutical Co., Ltd. | 402 | 2024-06-12 | 2026-02-18 |
| Postbiotic as Adjunct Treatment for Vaginal Candidiasis Postbiotic, Placebo - Vaginal Candidiasis | Phase 2 / Phase 3 | Completed | Min-Tze LIONG | 99 | 2024-06-02 | 2026-07-07 |
| Effect of PreforPro® on Urinary and Vaginal Health Preforpro, Placebo - Bacterial Vaginosis, Bacterial Infections | Phase 3 | Unknown | Jeremy Burton | 50 | 2024-05-01 | 2024-01-09 |
| Efficacy and Safety of Clotrimazole+Lactulose Vaginal Suppositories Vs. Clotrimazole Monotherapy in Adult Women with Candidal Vaginitis/Vulvovaginitis Clotrimazole+Lactulose., Canesten (Clotrimazole), Lactulose - Candidal Vulvovaginitis (ICD-10 Code: B37.3), Vulvovaginal Candidiasis (VVC) | Phase 2 / Phase 3 | Recruiting | AVVA Pharmaceuticals Ltd. | 264 | 2024-02-29 | 2025-02-19 |
| Vaginal Hyaluronic Acid, Arginine and Liposome Gel Versus Vaginal Lubricant in Postmenopausal Women With Genitourinary Syndrome of Menopause Vaginal Gel, Vaginal lubricant - Menopause Related Conditions, Atrophic Vaginitis | Phase 2 / Phase 3 | Unknown | Sarawak General Hospital | 52 | 2024-01-01 | 2023-12-28 |
| Efficacy and Safety of Natamycin and Lactulose Vaginal Suppositories in Treatment of Vulvovaginal Candidiasis Natamycin + Lactulose 100 mg + 300 mg vaginal suppositories, Lactulose 300 mg vaginal suppositories, Pimafucin® (natamycin) 100 mg vaginal suppositories - Vulvovaginal Candidiasis, Genital | Phase 3 | Completed | Avva Rus, JSC | 218 | 2022-12-29 | 2024-05-13 |
| The Effect of Medical Grade Honey Formulation (L-Mesitran) Administration on Recurrent Vulvovaginal Candidiasis Symptoms Fluconazole, L-Mesitran - Candidiasis, Vulvovaginal, Recurrent Candidiasis of Vagina | Phase 3 | Recruiting | Maastricht University Medical Center | 252 | 2022-08-22 | 2023-05-17 |
| Role of Oral Lactoferrin in Prevention of Recurnt Bacterial Vaginosis in Pregnancy lactoferrin - Bacterial Vaginosis | Vaginal | Microbiology | Phase 2 / Phase 3 | Unknown | Zagazig University | 66 | 2022-07-01 | 2023-01-03 |
| Ibrexafungerp for the Treatment of Complicated Vulvovaginal Candidiasis Ibrexafungerp - Vulvovaginal Candidiasis | Phase 3 | Completed | Scynexis, Inc. | 150 | 2022-05-01 | 2024-07-10 |
| Vaginal Cleaning Using Povidone Iodine Before CS to Reduce Postoperative Wound Infection 10% povidone iodine - Cesarean Section Complications, Vaginal Infection | Phase 3 | Unknown | Cairo University | 800 | 2021-09-15 | 2022-07-18 |
| A Study to Evaluate the Efficacy and Safety of SHR8008 vs. Fluconazole in Subjects With Recurrent Vulvovaginal Candidiasis SHR8008, Fluconazole - Recurrent Vulvovaginal Candidiasis | Phase 3 | Unknown | Jiangsu HengRui Medicine Co., Ltd. | 196 | 2021-09-14 | 2021-10-12 |
| Suppressive Antibacterial Therapy With Once-Weekly Secnidazole Granules to Prevent Recurrent Bacterial Vaginosis; A Pilot Study Secnidazole 2 GM Oral Granules - Recurrent Bacterial Vaginosis | Phase 2 / Phase 3 | Completed | Indiana University | 24 | 2021-07-09 | 2024-02-05 |
| Evaluation of Efficacy and Safety of Two New Formulations Compared to Gynomax® XL Ovule EVEGYN A, EVEGYN B, Gynomax® XL Vaginal Ovule - Trichomonal Vaginitis, Bacterial Vaginosis | Phase 3 | Completed | Ege University | 577 | 2020-07-20 | 2023-09-28 |
| DARE-BV1 in the Treatment of Bacterial Vaginosis (DARE-BVFREE) DARE-BV1clindamycin phosphate vaginal gel, 2% - Bacterial Vaginosis | Phase 3 | Completed | Daré Bioscience, Inc. | 307 | 2020-06-16 | 2022-12-08 |
| Treatment for Aerobic Vaginitis by Using Bofukang Vaginal Suppository Experimental: Baofukang Suppository 7 days, Experimental: Baofukang Suppository 14 days - Vaginitis | Phase 3 | Recruiting | Peking University Shenzhen Hospital | 50 | 2020-05-01 | 2025-06-12 |
| The ASPIRE Trial - Aiming for Safe Pregnancies by Reducing Malaria and Infections of the Reproductive Tract IPTp-sulphadoxine-pyrimethamine plus metronidazole, IPTp-dihydroartemisinin-piperaquine plus metronidazole, IPTp-sulphadoxine-pyrimethamine - Pregnancy Malaria, Bacterial Vaginoses | Phase 3 | Completed | London School of Hygiene and Tropical Medicine | 5436 | 2019-12-15 | 2023-05-22 |
| Phase 3 Study of Oral Ibrexafungerp (SCY-078) Vs. Placebo in Subjects With Recurrent Vulvovaginal Candidiasis (VVC) Fluconazole Tablet, IBREXAFUNGERP, Placebo oral tablet - Recurrent Vulvovaginal Candidiasis | Phase 3 | Completed | Scynexis, Inc. | 440 | 2019-10-21 | 2023-06-18 |
Showing 20 of 87. Sign in to see all of them.
Vaginosis, Bacterial (40) · Candidiasis, Vulvovaginal (25) · Atrophic Vaginitis (13) · Premature Birth (4) · Trichomonas Vaginitis (4) · Chlamydia Infections (3) · Gonorrhea (3) · Candidiasis (2) · HIV Infections (2) · Pruritus (2) · Recurrence (2) · Vulvovaginitis (2) · Abortion, Spontaneous (1) · Acquired Immunodeficiency Syndrome (1)
Female Urogenital Diseases (87) · Female Urogenital Diseases and Pregnancy Complications (87) · Genital Diseases (87) · Genital Diseases, Female (87) · Urogenital Diseases (86) · Vaginal Diseases (86) · Infections (63) · Bacterial Infections and Mycoses (62) · Bacterial Infections (39) · Vulvar Diseases (26) · Vulvitis (26) · Mycoses (25) · Candidiasis (24) · Vulvovaginitis (24)
Metronidazole (12) · Fluconazole (7) · Dehydroepiandrosterone (6) · ibrexafungerp (5) · Clotrimazole (4) · astodrimer (4) · Clindamycin (3) · Estradiol (3) · VT-1161 (3) · Vaginal Creams, Foams, and Jellies (3) · boric acid (3) · terconazole (3) · Azithromycin (2) · Ketoconazole (2) · Lactulose (2)
EndoCeutics Inc. (6) · Scynexis, Inc. (5) · Starpharma Pty Ltd (4) · Curatek Pharmaceuticals, LLC (3) · Mycovia Pharmaceuticals Inc. (3) · Actavis Inc. (2) · Assiut University (2) · Avva Rus, JSC (2) · Lumara Health, Inc. (2) · Medinova AG (2) · National Institute of Allergy and Infectious Diseases (NIAID) (2) · ProFem GmbH (2) · Symbiomix Therapeutics (2) · AVVA Pharmaceuticals Ltd. (1) · Alvogen Pine Brook LLC (1)
United States (39) · Canada (8) · Russia (6) · India (4) · Austria (3) · Brazil (3) · China (3) · Czechia (3) · France (3) · Germany (3) · Puerto Rico (3) · Slovakia (3) · Bulgaria (2) · Egypt (2) · Hungary (2)
David F Archer, MD (3) · Robert J Borgman, Ph.D. (3) · David F Archer, M.D. (2) · Jeremy Paull, PhD (2) · Jeremy Paull, PhD. (2) · Jim Joffrion (2) · Alfred Moffett, M.D. (1) · Amal Mohamed Alanwar, MD (1) · Arthur Waldbaum, M.D. (1) · Chemen Neal, MD (1) · Christine M Vaccaro, DO (1) · Claude Labrie, M.D., Ph.D. (1)
PMID 26972555, PMID 25968836, PMID 36396498, PMID 25734980, PMID 26291918, PMID 26517756, PMID 26597311, PMID 26634942, PMID 26731686, PMID 36255448, PMID 38319878, PMID 17128343, PMID 17666604, PMID 18532873, PMID 19220138, PMID 19321868, PMID 19389002, PMID 19424093, PMID 19436225, PMID 19436226, PMID 19616720, PMID 19936044, PMID 20370481, PMID 20459349, PMID 20591191, PMID 20801446, PMID 21216000, PMID 21244215, PMID 21489882, PMID 22059409, PMID 22205034, PMID 24774442, PMID 25511551, PMID 25771041, PMID 25887336, PMID 25935783, PMID 25961226, PMID 26210791, PMID 26509785, PMID 26611782, PMID 26725467, PMID 28640161, PMID 29474292, PMID 30002871, PMID 30807423, PMID 33207004, PMID 33383580, PMID 35675606, PMID 37098453, PMID 37431855
2008 (1), 2014 (1), 2017 (1), 2023 (1), UL1TR000135 (1)