414 completed, 101 unknown, 63 recruiting, 31 terminated. 224 Not applicable, 117 Phase 3, 112 Phase 2, 84 Phase 1, 56 Phase 4.
Follow Vaginal Diseases: new trials by email Literature Review of Vaginal Diseases trials Research Report on Vaginal Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Test New Investigational Drugs (LCFA-01and LC103) for Bacterial Vaginosis (BV) Treatment metronidazole (MTZ)+ LCFA-01 placebo + LC103 placebo, metronidazole (MTZ)+ LCFA-01 + LC103 placebo, metronidazole (MTZ)+ LC103 + LCFA-01 placebo - Bacterial Vaginosis | Phase 1 | Not yet recruiting | Massachusetts General Hospital | 280 | 2027-02-03 | 2026-10-15 |
| Prevention of Vaginal Cuff Infection After Hysterectomy by Addition of Vaginal Clindamycin Clindamycin Vaginal Gel - Surgical Site Infection, Vaginal Cuff Cellulitis | Enrolling by invitation | Baylor Research Institute | 900 | 2026-12-01 | 2026-10-22 | |
| Emerging Indications for Hyperbaric Oxygen Treatment Hyperbaric oxygen treatment (HBOT), 100% Oxygen - Post-COVID-19 Condition, Ulcerative Colitis | Phase 4 | Not yet recruiting | Jay C. Buckey Jr. | 100 | 2026-11-01 | 2026-09-09 |
| Effect of Multimodal Physical Therapy on Vaginismus Secondary to Chronic Constipation Conventional physiotherapy, Multimodal physical therapy program - Vaginismus, Chronic Constipation | Not applicable | Not yet recruiting | Cairo University | 40 | 2026-11-01 | 2026-11-09 |
| WST03 Capsule Combined With Metronidazole for Bacterial Vaginosis High-dose WST03 Vaginal Capsule Metronidazole, Low-dose WST03 Vaginal Capsule Metronidazole, Placebo Vaginal Capsule Metronidazole - Bacterial Vaginosis (BV) | Phase 2 | Not yet recruiting | SPH Sine Pharmaceutical Laboratories Co., Ltd. | 150 | 2026-10-20 | 2026-10-22 |
| Radiotherapy for Gynecologic Cancer With Up to 10 Active Metastatic Lesions Routine-care metastasis-directed radiotherapy - Cervical Cancer, Gynecologic Cancer | Recruiting | Affidea Nu-med Center of Oncological DIagnostics and Therapy | 500 | 2026-10-06 | 2026-10-23 | |
| AUTOP 2: Screen-and-treat Strategy for Vaginal Flora Abnormalities by Molecular Biology in Pregnant Women at High Risk of Preterm Birth Vaginal flora abnormalities screening and quantification using molecular biology technique, Azithromycin, Ceftriaxone - Bacterial Vaginosis, Vaginal Dysbiosis | Phase 3 | Not yet recruiting | Assistance Publique Hopitaux De Marseille | 1794 | 2026-10-01 | 2026-08-27 |
| Photobiomodulation With Blue LED in Recurrent Bacterial Vaginosis Metronidazole, Blue Light-Emitting Diode (LED) - Bacterial Vaginosis | Not applicable | Not yet recruiting | Patricia Lordelo | 40 | 2026-09-30 | 2026-09-23 |
| Vagina-View Safety and Imaging Feasibility Vagina-View (VV) device - Vaginal Cancer | Not applicable | Recruiting | University Health Network, Toronto | 10 | 2026-09-15 | 2026-09-17 |
| A Blended e-Health Intervention to Improve Fear of Progression in Women With Gynecologic or Breast Cancer Best Practice, Interview, Supportive Care - Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | Not applicable | Recruiting | City of Hope Medical Center | 126 | 2026-09-09 | 2026-10-16 |
| Implementing Virtual Reality Exposure Therapy for Vaginismus: From Efficacy to Clinical Integration (VIVID 3) Implementation of Virtual Reality Exposure - Vaginismus, Difficulties With Vaginal Penetration | Not applicable | Not yet recruiting | University of British Columbia | 167 | 2026-09-01 | 2026-08-05 |
| Vaginal Estradiol vs Moisturizer to Improve Postmenopausal Vaginal Aging Symptoms and the Microbiome in Women Living With HIV Vaginal estradiol tablets, Vaginal moisturizer - Menopausal Complaints, Vaginal Atrophy | Phase 4 | Not yet recruiting | Albert Einstein College of Medicine | 62 | 2026-09-01 | 2026-07-28 |
| MOTIF@FRESH: Modifying Organisms Transvaginally in Females @ FRESH Vaginal Microbiome Transplantation (VMT), oral metronidazole, Sterile saline solution - Recurrent Bacterial Vaginosis (BV) | Phase 2 | Not yet recruiting | Douglas Kwon | 75 | 2026-09-01 | 2026-05-18 |
| Measuring Pelvic Floor Muscle Fitness Before and After Treatment Near Infrared Imaging - Myofacial Pain, Pelvic Pain | Not applicable | Not yet recruiting | University of California, Los Angeles | 120 | 2026-09-01 | 2026-05-26 |
| A Randomized, Multicenter, Open-label, Active-controlled Phase Ib Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of Multiple Intravaginal Doses of GenSci142 in Patients With Bacterial Vaginosis (BV) GenSci142 capsule, clindamycin phosphate vaginal cream - Randomized, Open-label | Phase 1 | Recruiting | Changchun GeneScience Pharmaceutical Co., Ltd. | 42 | 2026-08-15 | 2026-10-15 |
| Improving Maternal and Child Health Through Point-of-care STI Testing Point-of-care STI tests, Standard of care STI testing - Treponema Pallidum Infection, Chlamydia Trachomatis Infection | Not applicable | Recruiting | Emory University | 756 | 2026-08-11 | 2026-08-19 |
| Photobiomodulation for Vaginal Dysfunctions: Home-Based vs Outpatient Treatment Blue LED Photobiomodulation - Genitourinary Syndrome of Menopause (GSM), Bacterial Vaginosis | Not applicable | Not yet recruiting | Patricia Lordelo | 150 | 2026-07-30 | 2026-07-13 |
| F-GYN for Vaginal Dryness and Vulvovaginal Atrophy F-GYN Non-Crosslinked Hyaluronic Acid Injectable Gel, Standard Non-Hormonal Symptomatic Care - Atrophic Vaginitis, Atrophic Vulvovaginitis | Not applicable | Recruiting | Biovico Sp. z o.o. | 130 | 2026-07-24 | 2026-10-01 |
| Immersive Visual Modulation and Ambient Music Therapy During Transvaginal Ultrasonography in Women With Vaginismus Standard Care, Immersive Visual Modulation (IVM), Ambient Music Therapy (AMT) - Vaginismus | Not applicable | Enrolling by invitation | Demet Mutlu | 90 | 2026-07-16 | 2026-09-23 |
| Virtual Mental Health Intervention to Address Fear of Progression for Women With High Risk or Stage III-IV Gynecologic or Breast Cancer Behavioral Intervention, Educational Intervention, Internet-Based Intervention - Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8 | Not applicable | Withdrawn | City of Hope Medical Center | 2026-07-16 | 2026-02-04 |
Showing 20 of 682. Sign in to see all of them.
Vaginosis, Bacterial (235) · Vaginal Neoplasms (158) · Uterine Cervical Neoplasms (141) · Vulvar Neoplasms (115) · Candidiasis, Vulvovaginal (107) · Vaginitis (98) · Endometrial Neoplasms (73) · Ovarian Neoplasms (58) · Atrophic Vaginitis (44) · Fallopian Tube Neoplasms (37) · Anus Neoplasms (33) · Uterine Neoplasms (29) · Vaginismus (29) · Carcinoma, Ovarian Epithelial (28)
Female Urogenital Diseases and Pregnancy Complications (682) · Genital Diseases (682) · Female Urogenital Diseases (679) · Urogenital Diseases (678) · Genital Diseases, Female (677) · Infections (381) · Vaginitis (337) · Bacterial Infections and Mycoses (329) · Bacterial Infections (237) · Vulvar Diseases (231) · Neoplasms by Site (163) · Urogenital Neoplasms (159) · Uterine Diseases (158) · Genital Neoplasms, Female (152)
Metronidazole (53) · Fluconazole (23) · Clotrimazole (12) · Clindamycin (11) · Radiotherapy (11) · Probiotics (10) · Brachytherapy (8) · Dehydroepiandrosterone (8) · Estradiol (8) · ibrexafungerp (8) · Surveys and Questionnaires (7) · Magnetic Resonance Spectroscopy (6) · Ospemifene (6) · VT-1161 (6) · secnidazole (6)
M.D. Anderson Cancer Center (11) · Merck Sharp & Dohme LLC (11) · National Cancer Institute (NCI) (10) · National Institute of Allergy and Infectious Diseases (NIAID) (9) · Gedea Biotech AB (8) · Scynexis, Inc. (8) · University of Pittsburgh (8) · Assiut University (7) · Peking University Shenzhen Hospital (7) · Shanghai Bovax Biotechnology Co., Ltd. (7) · EndoCeutics Inc. (6) · Memorial Sloan Kettering Cancer Center (6) · Ohio State University Comprehensive Cancer Center (6) · Shionogi (6) · Starpharma Pty Ltd (6)
United States (258) · China (46) · Canada (30) · France (25) · United Kingdom (24) · Italy (21) · Israel (17) · Spain (17) · Brazil (15) · Egypt (15) · Sweden (14) · Germany (13) · Belgium (11) · India (11) · Turkey (Türkiye) (11)
Shangrong Fan, M.D. (5) · Anne Reb (3) · Clare Shaw, Phd (3) · David Angulo, MD (3) · David F Archer, MD (3) · Jeremy Paull, PhD (3) · Robert J Borgman, Ph.D. (3) · Sharon L Hillier, PhD (3) · Alena Jandourek, MD (2) · Allison M Quick, MD (2) · Andrea R Thurman, MD (2)
PMID 26972555, PMID 36396498, PMID 25968836, PMID 27422279, PMID 40709601, PMID 19949018, PMID 21854593, PMID 22002018, PMID 23985562, PMID 25734980, PMID 26291918, PMID 26517756, PMID 26597311, PMID 26634942, PMID 26731686, PMID 29211620, PMID 29269325, PMID 29767739, PMID 33207004, PMID 33326342, PMID 36255448, PMID 37431855, PMID 37619252, PMID 38319878, PMID 40970688, PMID 10028110, PMID 10371477, PMID 11166145, PMID 11230468, PMID 11425832, PMID 11463927, PMID 11576584, PMID 12015520, PMID 12048413, PMID 12625969, PMID 12762087, PMID 12861145, PMID 12954522, PMID 14672465, PMID 15008773, PMID 15028938, PMID 1504154, PMID 15089868, PMID 15118630, PMID 15291998, PMID 1535108, PMID 15458898, PMID 15902186, PMID 16145097, PMID 16303068
2023 (3), P30CA033572 (3), P30CA043703 (3), 2009 (2), 2014 (2), 2017 (2), R21CA293326 (2), U01CA062502 (2), U10CA180868 (2), 2008 (1), 2019 (1), 2025 (1), K23AG062400 (1), KL2RR025754 (1), P30AI027757 (1)