261 completed, 79 recruiting, 57 unknown, 34 terminated. 178 Not applicable, 107 Phase 2, 63 Phase 3, 52 Phase 1, 13 Phase 4.
Follow Vulvar Diseases: new trials by email Literature Review of Vulvar Diseases trials Research Report on Vulvar Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Pilot Study on the Efficacy of Oral Low Dose Naltrexone for Vulvodynia Low Dose Naltrexone - Vulvodynia | Phase 2 | Not yet recruiting | University of Florida | 20 | 2027-01-01 | 2026-10-09 |
| Transcutaneous Genital Nerves Stimulation for the Treatment of Refractory Chronic Pelvic and Genital Pain in Women. Transcutaneous Genital Nerves Stimulation - Refractory Visceral Pelvic Pain, Refractory Genital Pain | Not applicable | Not yet recruiting | Prof. Dr. med. Marc Possover | 50 | 2026-12-01 | 2026-10-20 |
| Tisotumab Vedotin in Squamous Cell Carcinoma of the Vulva Tisotumab Vedotin - Vulvar Carcinoma, Recurrent or Metastatic Vulvar Cancer | Phase 2 | Not yet recruiting | GOG Foundation | 28 | 2026-11-01 | 2026-06-29 |
| Needlefree Lidocaine Application for Vulvar Biopsies J-Tip, Lidocaine HCl 1% - Vulvar Cancers, Vulva Neoplasm | Not applicable | Not yet recruiting | Tufts Medical Center | 106 | 2026-11-01 | 2026-08-28 |
| Radiotherapy for Gynecologic Cancer With Up to 10 Active Metastatic Lesions Routine-care metastasis-directed radiotherapy - Cervical Cancer, Gynecologic Cancer | Recruiting | Affidea Nu-med Center of Oncological DIagnostics and Therapy | 500 | 2026-10-06 | 2026-10-20 | |
| Comparative Trial Between Open and Single-port Robotic-assisted Groin Lymphadenectomy in Vulvar Cancer Inguinofemoral lymphadenectomy - Vulvar Cancers | Not applicable | Not yet recruiting | Karolinska Institutet | 64 | 2026-10-01 | 2026-10-01 |
| A Blended e-Health Intervention to Improve Fear of Progression in Women With Gynecologic or Breast Cancer Best Practice, Interview, Supportive Care - Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | Not applicable | Recruiting | City of Hope Medical Center | 126 | 2026-09-09 | 2026-10-16 |
| CPP Among Somali Women in Norway: SCED Multimodal physiotherapy - Chronic Pelvic Pain | Not applicable | Not yet recruiting | Kristiania University College | 30 | 2026-09-01 | 2026-09-15 |
| Nemolizumab for LS Nemolizumab 30 mg - Lichen Sclerosus of Vulva | Phase 2 | Not yet recruiting | University of Texas Southwestern Medical Center | 25 | 2026-09-01 | 2026-07-15 |
| Intraoperative Microscopic Assessment of Lymph Node Status in Gynecological Malignancies Gynecologic Cancer, Cervical Cancer | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 160 | 2026-08-01 | 2026-07-14 | |
| Photobiomodulation for Vaginal Dysfunctions: Home-Based vs Outpatient Treatment Blue LED Photobiomodulation - Genitourinary Syndrome of Menopause (GSM), Bacterial Vaginosis | Not applicable | Not yet recruiting | Patricia Lordelo | 150 | 2026-07-30 | 2026-07-13 |
| Virtual Mental Health Intervention to Address Fear of Progression for Women With High Risk or Stage III-IV Gynecologic or Breast Cancer Behavioral Intervention, Educational Intervention, Internet-Based Intervention - Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8 | Not applicable | Withdrawn | City of Hope Medical Center | 2026-07-16 | 2026-02-04 | |
| A Single-arm, Multicenter Clinical Study of Becotatug Vedotin Combined With Zimberelimab in the Treatment of Recurrent and Metastatic Cervical Cancer, Vulvar Cancer and Vaginal Cancer Becotatug Vedotin in combination with Zimberelimab - Uterine Cervical Neoplasms, Recurrent; Uterine Cervical Neoplasms, Metastatic; Vulvar Neoplasms; Vaginal Neoplasms | Phase 2 | Recruiting | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 30 | 2026-06-11 | 2026-06-16 |
| Reirradiation and Total Ablative Strategies for Recurrent Gynecologic Cancer Reirradiation, Total Ablative Strategy - Recurrent Gynecologic Cancer, Recurrent Uterine Cancer | Recruiting | Affidea Nu-med Center of Oncological DIagnostics and Therapy | 500 | 2026-06-11 | 2026-10-16 | |
| Biweekly Long-term Occidiofungin Study for Suppression of Mycotic Recurrence OCF001 Intravaginal Gel, Placebo Gel - Candidiasis, Vulvovaginal | Phase 2 | Recruiting | Sano Chemicals Inc | 36 | 2026-06-04 | 2026-06-15 |
| Large Algorithm Setting and Validation Study Nanopath Vaginitis Assay, BD Max™ Vaginal Panel, Cepheid Xpert® Xpress MVP - Bacterial Infections, Bacterial Infections and Mycoses | Recruiting | Nanopath, Inc | 1000 | 2026-06-03 | 2026-07-20 | |
| A Phase III Randomised Clinical Trial of Ultrasound Groin Monitoring Versus Groin Lymph Node Dissection to De-Escalate the Extent of Surgery in Vulvar Cancer High-resolution bilateral groin ultrasound monitoring - Vulvar Cancer Stage I, Vulvar Cancer Stage II | Phase 3 | Not yet recruiting | Queensland Centre for Gynaecological Cancer | 640 | 2026-06-01 | 2026-03-24 |
| Evaluation of the Efficacy of a Probiotic Product as an Adjuvant Treatment for Vulvovaginal Candidiasis Bioithas WOMAN® - Vulvovaginal Candidiasis (VVC) | Not applicable | Recruiting | Bioithas SL | 60 | 2026-05-25 | 2026-05-22 |
| Efficacy of Dry Needling in Reducing Pain During Sexual Intercourse Real dry needling, Sham dry needling - Provoked Vestibulodynia | Not applicable | Recruiting | Université de Sherbrooke | 170 | 2026-05-11 | 2026-05-12 |
| Quality of Life and Sexuality After Pelvic Exenteration for Gynecologic Cancer Cervical Cancers, Vaginal Cancers | Enrolling by invitation | Tampere University Hospital | 21 | 2026-05-01 | 2026-05-22 |
Showing 20 of 501. Sign in to see all of them.
Vulvar Neoplasms (236) · Uterine Cervical Neoplasms (156) · Vaginal Neoplasms (114) · Candidiasis, Vulvovaginal (107) · Vulvodynia (107) · Endometrial Neoplasms (74) · Ovarian Neoplasms (72) · Anus Neoplasms (46) · Fallopian Tube Neoplasms (39) · Vulvar Lichen Sclerosus (33) · Breast Neoplasms (32) · Penile Neoplasms (31) · Uterine Neoplasms (31) · Neoplasms (28) · Vaginosis, Bacterial (27)
Female Urogenital Diseases and Pregnancy Complications (501) · Genital Diseases (501) · Female Urogenital Diseases (499) · Urogenital Diseases (499) · Genital Diseases, Female (496) · Neoplasms by Site (236) · Urogenital Neoplasms (234) · Vaginal Diseases (227) · Genital Neoplasms, Female (226) · Neoplasms (212) · Uterine Diseases (164) · Uterine Cervical Diseases (159) · Infections (146) · Vulvitis (132)
Fluconazole (21) · Radiotherapy (10) · Cisplatin (9) · Surveys and Questionnaires (9) · Clobetasol (8) · Clotrimazole (8) · ibrexafungerp (8) · Lidocaine (6) · Methods (6) · VT-1161 (6) · pembrolizumab (6) · Acupuncture Therapy (5) · Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18 (5) · Botulinum Toxins, Type A (4) · Brachytherapy (4)
Merck Sharp & Dohme LLC (12) · Gynecologic Oncology Group (11) · M.D. Anderson Cancer Center (8) · National Cancer Institute (NCI) (8) · Scynexis, Inc. (8) · Université de Sherbrooke (8) · Western Galilee Hospital-Nahariya (7) · Ohio State University Comprehensive Cancer Center (6) · Corewell Health East (5) · Dana-Farber Cancer Institute (5) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (5) · Gedea Biotech AB (5) · Karolinska Institutet (5) · Northwestern University (5) · Shanghai Bovax Biotechnology Co., Ltd. (5)
United States (207) · Canada (34) · China (31) · United Kingdom (21) · Italy (20) · Sweden (20) · France (19) · Brazil (12) · Turkey (Türkiye) (11) · Germany (10) · Spain (10) · Israel (9) · Switzerland (9) · Austria (7) · Poland (7)
Lori A Brotto, PhD (4) · Anne Reb (3) · Catherine Leclair, MD (3) · Clare Shaw, Phd (3) · David Angulo, MD (3) · Fabien Pelletier, MD (3) · Jacob Bornstein, MD (3) · Shangrong Fan, M.D. (3) · Yongjiang Liu, Bachelor (3) · Alena Jandourek, MD (2) · Allison M Quick, MD (2) · Andrew T Goldstein, MD (2)
PMID 36396498, PMID 27422279, PMID 19949018, PMID 20686386, PMID 22002018, PMID 23290987, PMID 29211620, PMID 29269325, PMID 29767739, PMID 32734597, PMID 33326342, PMID 33957642, PMID 36255448, PMID 38319878, PMID 40970688, PMID 10319301, PMID 15162347, PMID 16648432, PMID 17012991, PMID 17034521, PMID 17128343, PMID 18482765, PMID 18768432, PMID 18981976, PMID 19305326, PMID 19487487, PMID 19701032, PMID 20059663, PMID 20068553, PMID 20733439, PMID 22480131, PMID 22675922, PMID 22753905, PMID 22914465, PMID 23107862, PMID 23335087, PMID 23384847, PMID 23526734, PMID 23535473, PMID 23849695, PMID 24067488, PMID 24080300, PMID 24201015, PMID 24696010, PMID 24807329, PMID 25278227, PMID 25540035, PMID 25603224, PMID 25618900, PMID 25693011
2023 (6), P30CA033572 (3), U10CA027469 (3), U10CA101165 (3), U10CA180868 (3), 2009 (2), 2016 (2), 2017 (2), 2019 (2), P30CA012197 (2), R21CA293326 (2), UG1CA189867 (2), 2008 (1), 2014 (1), 2015 (1)