25 completed, 17 unknown, 8 recruiting, 6 active not recruiting. 35 Not applicable, 8 Phase 2, 8 Phase 3, 5 Phase 4, 3 Phase 1.
Follow Urethral Stricture: new trials by email Literature Review of Urethral Stricture trials Research Report on Urethral Stricture
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Feasibility Study of Autologous Engineered Urethral Constructs for the Treatment of Strictures Autologous Engineered Urethral Construct - Urologic Diseases, Male Urogenital Diseases | Phase 1 | Recruiting | Wake Forest University Health Sciences | 10 | 2027-01-01 | 2026-07-28 |
| REDUCER Trial (TXA in Urethroplasty) Tranexamic Acid, Urethroplasty - Urethral Stricture, Urethral Diseases | Phase 4 | Not yet recruiting | Amjad Alwaal, MD, MSc, FRCSC, FACS | 40 | 2026-09-01 | 2026-08-13 |
| Comparison Between Excision And Primary Anastomosis Urethroplasty And Tunica Vaginalis Graft Urethroplasty. Excision and Primary Anastomosis Urethroplasty, Tunica Vaginalis Graft Urethroplasty - Urethral Stricture, Erectile Dysfunction | Not applicable | Not yet recruiting | Sahiwal medical college sahiwal | 94 | 2026-08-01 | 2026-08-05 |
| Intraoperative Lidocaine or Dexmedetomidine for Postoperative Pain Modulation After Urethral Reconstruction. Perioperative lidocaine infusion, Perioperative dexmedetomidine infusion, Perioperative placebo infusion - Urethral Stricture | Not applicable | Recruiting | Centre of Postgraduate Medical Education | 80 | 2026-07-07 | 2026-10-09 |
| A Comparative Study of the Antibacterial Effects of Two Preoperative Hair Removal Methods in Male Patients With Urethral Stricture Wiping with wet wipes containing 2% chlorhexidine gluconate (CHG). - Urethral Stricture | Not applicable | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 40 | 2026-04-01 | 2026-04-02 |
| Urethral Resistive Index (URI): A New Parameter for Diagnosing Urethral Obstruction Uroflowmetry with URI Calculation - Urethral Stricture | Recruiting | Ankara City Hospital Bilkent | 60 | 2026-02-10 | 2026-04-06 | |
| The Impact of Age and Sex on Anticipated and Experienced Pain in First-Time Outpatient Flexible Cystoscopy Urethral Stricture, Bladder (Urothelial, Transitional Cell) Cancer | Not yet recruiting | Kayseri Education and Research Hospital | 150 | 2026-02-01 | 2026-01-29 | |
| The Effects of Holmium Laser Enucleation and Thulium Laser Enucleation on Continence, Urethral Stricture, and Sexual Function in Benign Prostatic Hyperplasia Benign Prostate Obstruction (BPO) | Not yet recruiting | TC Erciyes University | 200 | 2026-02-01 | 2026-01-12 | |
| Risk of Recurrent Urethral Stricture After Treatment With Paclitaxel-Coated Dilatation Balloon (Optilume) Compared With Non-coated Dilatation Balloon Optilume, UroMax Ultra - Urethral Stricture | Phase 4 | Recruiting | Vastra Gotaland Region | 230 | 2026-01-16 | 2026-01-16 |
| Holmium Laser Versus Cold Knife Treatment in Urethral Strictures holmium laser, cold knife - Stricture Urethra, Holmium Laser | Not applicable | Completed | Shahida Islam Medical Complex | 60 | 2026-01-15 | 2026-04-21 |
| LishitonglinUS-01 Trial Lishitonglin Formula granules, Oral placebo medication formulated as granules - Urethra Stricture | Phase 2 | Active not recruiting | Peking University First Hospital | 120 | 2026-01-09 | 2026-08-17 |
| Platelet Rich Plasma Versus Mitomycin C Injection Following Visual Internal Urethrotomy in Urethral Stricture Visual internal urethrotomy followed by submucosal intralesional mitomycin C injection, Visual internal urethrotomy followed by submucosal Platlet Rich Plasma injection - Urethral Stricture | Phase 3 | Completed | Ain Shams University | 50 | 2025-08-01 | 2026-10-20 |
| Treatment of Bulbar Urethral Strictures With Optilume Drug-Coated Balloons in an Untreated Population Optilume DCB, Standard Direct Visual Internal Urethrotomy (DVIU) - Urethral Stricture, Urethral Stricture, Anterior | Not applicable | Not yet recruiting | Aalborg University Hospital | 140 | 2025-02-07 | 2025-02-14 |
| Outcomes of Double-face Augmentation Urethroplasty Double-face augmentation urethroplasty - Urethral Stricture, Anterior, Urethral Stricture Disease | Not applicable | Active not recruiting | Menoufia University | 30 | 2025-02-01 | 2026-10-07 |
| Penile Skin Versus Buccal Mucosal Graft in Augmentation Urethroplasty for Long Anterior Urethral Stricture Buccal Mucosal Graft (BMG) Urethroplasty, Penile Skin Graft (PSG) Urethroplasty - Penile Skin, Buccal Mucosal Graft | Not applicable | Recruiting | Tanta University | 80 | 2025-01-01 | 2025-07-20 |
| Optimal Duration of Foley Catheter After Bulbar Urethroplasty Early catheter removal, Later catheter removal - Urethral Stricture, Bulbar | Not applicable | Enrolling by invitation | Jane Kurtzman | 320 | 2024-08-28 | 2026-02-27 |
| Effectiveness of Intermittent Bladder Catheterization (IBC) in Reducing Recurrence of Urethral Stricture Intermittent bladder catheterization - Urethral Stricture | Not applicable | Completed | University of Health Sciences Lahore | 54 | 2024-06-20 | 2024-12-11 |
| Safety and Potential Effect of Innovative Treatment by Adjuvant Injection of Stromal Vascular Fraction From Autologous Adipose Tissue of URethral Stenosis With Endoscopic Urethrotomy lipoaspiration, urethrotomy, autologous ADSVF administration - Urethral Stenosis | Phase 2 | Recruiting | Assistance Publique Hopitaux De Marseille | 20 | 2024-03-13 | 2026-02-04 |
| The Effect of Platelet Rich Plasma Injection on Post Internal Urethrotomy Stricture Recurrence PRP injection, VIU - Stricture Urethra | Phase 3 | Completed | Benha University | 156 | 2024-02-19 | 2026-09-23 |
| Urethral Stricture Database Questionnaires and data collection - Urethral Stricture | Recruiting | Medical University of Graz | 500 | 2024-01-15 | 2024-04-12 |
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Lower Urinary Tract Symptoms (3) · Constriction, Pathologic (2) · Hypospadias (2) · Pain, Postoperative (2) · Urinary Tract Infections (2) · Urologic Diseases (2) · Agnosia (1) · Bites and Stings (1) · Erectile Dysfunction (1) · Fibrosis (1) · Hemorrhage (1) · Male Urogenital Diseases (1) · Neoplasms (1) · Neuralgia (1)
Female Urogenital Diseases (67) · Female Urogenital Diseases and Pregnancy Complications (67) · Urethral Obstruction (67) · Urogenital Diseases (67) · Male Urogenital Diseases (66) · Urethral Diseases (66) · Urologic Diseases (65) · Pathological Conditions, Signs and Symptoms (13) · Pathologic Processes (6) · Signs and Symptoms (6) · Genital Diseases (4) · Genital Diseases, Male (4) · Urological Manifestations (4) · Infections (3) · Pathological Conditions, Anatomical (3)
Lasers, Solid-State (2) · Acetaminophen (1) · Bupivacaine (1) · Calcium Dobesilate (1) · Celecoxib (1) · Chromogranins (1) · Conization (1) · Data Collection (1) · Dexamethasone (1) · Epinephrine (1) · Gabapentin (1) · Ibuprofen (1) · Microbial Collagenase (1) · Mitomycin (1) · Oxycodone (1)
University Hospital, Ghent (6) · Ain Shams University (5) · Urotronic Inc. (5) · Al-Azhar University (3) · University of California, San Francisco (2) · University of Roma La Sapienza (2) · Aalborg University Hospital (1) · Amjad Alwaal, MD, MSc, FRCSC, FACS (1) · Ankara City Hospital Bilkent (1) · Assistance Publique Hopitaux De Marseille (1) · Baylor College of Medicine (1) · Benha University (1) · Centre of Postgraduate Medical Education (1) · European Association of Urology Research Foundation (1) · Hannes Kortekangas (1)
United States (18) · Egypt (12) · Belgium (8) · China (4) · Italy (3) · Spain (3) · Turkey (Türkiye) (3) · Canada (2) · Finland (2) · Israel (2) · Norway (2) · Pakistan (2) · Poland (2) · Sweden (2) · United Kingdom (2)
Nicolaas Lumen (3) · Wesley Verla (3) · Sean Elliott, MD (2) · Ahmed Fahim, professor (1) · Ahmed M Reyad, MD (1) · Alexander Schultz, MD (1) · Amjad Alwaal, MD, MSc, FACS (1) · Andrey Vinarov, Dr., Prof. (1) · Antonio Luigi Pastore, Prof (1) · Brasil S Neto, Phd MD (1) · Charlotte H Graugaard-Jensen, MD, PHD (1) · Denis Butnaru, Dr. (1) · Deyi Luo (1) · Dmitriy Nikolavsky, MD (1) · Dr.sabhee UbaidUllah (1)
PMID 34854748, PMID 15541123, PMID 17437780, PMID 17617144, PMID 20554319, PMID 21315996, PMID 22611164, PMID 23376148, PMID 24745607, PMID 26126692, PMID 26491251, PMID 26494995, PMID 26609447, PMID 27207599, PMID 28479479, PMID 30409684, PMID 30622707, PMID 32692990, PMID 32917251, PMID 35249203, PMID 35572815, PMID 39213367, PMID 41506760, PMID 42305123, PMID 9679876
K12DK083021 (1)