117 completed, 33 unknown, 22 active not recruiting, 18 recruiting. 74 Phase 2, 63 Not applicable, 32 Phase 1, 20 Phase 3, 11 Phase 4.
Follow Urethral Diseases: new trials by email Literature Review of Urethral Diseases trials Research Report on Urethral Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Feasibility Study of Autologous Engineered Urethral Constructs for the Treatment of Strictures Autologous Engineered Urethral Construct - Urologic Diseases, Male Urogenital Diseases | Phase 1 | Recruiting | Wake Forest University Health Sciences | 10 | 2027-01-01 | 2026-07-28 |
| High Intensity Focused Ultrasound (HIFU) Ablation for Treatment of Prostate Tissue in Bladder Outlet Obstruction High Intensity Focused Ultrasound - Bladder Outlet Obstruction, BPH | Not applicable | Not yet recruiting | Icahn School of Medicine at Mount Sinai | 17 | 2026-11-01 | 2026-10-09 |
| Omadacycline for Treatment Refractory Mycoplasma Genitalium Urethritis Omadacycline Oral Tablet - Mycoplasma Genitalium Infection, Urethritis | Phase 2 | Not yet recruiting | Montefiore Medical Center | 10 | 2026-10-01 | 2026-10-02 |
| REDUCER Trial (TXA in Urethroplasty) Tranexamic Acid, Urethroplasty - Urethral Stricture, Urethral Diseases | Phase 4 | Not yet recruiting | Amjad Alwaal, MD, MSc, FRCSC, FACS | 40 | 2026-09-01 | 2026-08-13 |
| Comparison Between Excision And Primary Anastomosis Urethroplasty And Tunica Vaginalis Graft Urethroplasty. Excision and Primary Anastomosis Urethroplasty, Tunica Vaginalis Graft Urethroplasty - Urethral Stricture, Erectile Dysfunction | Not applicable | Not yet recruiting | Sahiwal medical college sahiwal | 94 | 2026-08-01 | 2026-08-05 |
| Intraoperative Lidocaine or Dexmedetomidine for Postoperative Pain Modulation After Urethral Reconstruction. Perioperative lidocaine infusion, Perioperative dexmedetomidine infusion, Perioperative placebo infusion - Urethral Stricture | Not applicable | Recruiting | Centre of Postgraduate Medical Education | 80 | 2026-07-07 | 2026-10-09 |
| Thulium Laser Enucleation With Bladder Neck Incision for Small-Volume Benign Prostatic Hyperplasia Thulium Laser Enucleation of the Prostate Combined With Bladder Neck Incision, Thulium Laser Enucleation of the Prostate, Transurethral Resection of the Prostate - Benign Prostatic Hyperplasia, Bladder Outlet Obstruction | Not applicable | Not yet recruiting | Chinese PLA General Hospital | 932 | 2026-07-01 | 2026-07-21 |
| Comparison of Concurrent Endoscopic Prostate Surgery With Botox-A Injection and Postoperative Medical Therapy in BPH Patients With Overactive Bladder Symptoms Urinary Bladder, Overactive, Prostatic Hyperplasia, Benign | Active not recruiting | Taksim Egitim ve Arastirma Hastanesi | 70 | 2026-04-01 | 2026-04-28 | |
| A Comparative Study of the Antibacterial Effects of Two Preoperative Hair Removal Methods in Male Patients With Urethral Stricture Wiping with wet wipes containing 2% chlorhexidine gluconate (CHG). - Urethral Stricture | Not applicable | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 40 | 2026-04-01 | 2026-04-02 |
| Urinary CTGF in Benign Prostatic Obstruction None-placebo - Benign Prostatic Hyperplasia, Bladder Outlet Obstruction | Not yet recruiting | Tarik Emre Sener | 50 | 2026-04-01 | 2026-02-18 | |
| Urethral Resistive Index (URI): A New Parameter for Diagnosing Urethral Obstruction Uroflowmetry with URI Calculation - Urethral Stricture | Recruiting | Ankara City Hospital Bilkent | 60 | 2026-02-10 | 2026-04-06 | |
| Effect of Catheter Duration on Prostate Laser Enucleation Surgery Outcomes in Patients With Urinary Retention Laser Enucleation of the Prostate (HoLEP, ThuLEP, ThuFLEP) - Urinary Retention, Benign Prostate Obstruction (BPO) | Recruiting | Eskişehir Osmangazi University Medicine Faculty Hospital | 54 | 2026-02-04 | 2026-09-11 | |
| The Impact of Age and Sex on Anticipated and Experienced Pain in First-Time Outpatient Flexible Cystoscopy Urethral Stricture, Bladder (Urothelial, Transitional Cell) Cancer | Not yet recruiting | Kayseri Education and Research Hospital | 150 | 2026-02-01 | 2026-01-29 | |
| The Effects of Holmium Laser Enucleation and Thulium Laser Enucleation on Continence, Urethral Stricture, and Sexual Function in Benign Prostatic Hyperplasia Benign Prostate Obstruction (BPO) | Not yet recruiting | TC Erciyes University | 200 | 2026-02-01 | 2026-01-12 | |
| Predictors of Trifecta Achievement After HoLEP Transurethral Holmium Laser Enuclation of the Prostate - HoLEP, Trifecta Achievement | Not applicable | Not yet recruiting | Ondokuz Mayıs University | 604 | 2026-01-30 | 2026-02-24 |
| Risk of Recurrent Urethral Stricture After Treatment With Paclitaxel-Coated Dilatation Balloon (Optilume) Compared With Non-coated Dilatation Balloon Optilume, UroMax Ultra - Urethral Stricture | Phase 4 | Recruiting | Vastra Gotaland Region | 230 | 2026-01-16 | 2026-01-16 |
| Holmium Laser Versus Cold Knife Treatment in Urethral Strictures holmium laser, cold knife - Stricture Urethra, Holmium Laser | Not applicable | Completed | Shahida Islam Medical Complex | 60 | 2026-01-15 | 2026-04-21 |
| LishitonglinUS-01 Trial Lishitonglin Formula granules, Oral placebo medication formulated as granules - Urethra Stricture | Phase 2 | Active not recruiting | Peking University First Hospital | 120 | 2026-01-09 | 2026-08-17 |
| Ultrasound IPP to Predict Response to Medical Therapy in LUTS/BPH Transabdominal ultrasound measurement of intravesical prostatic protrusion, Alpha-adrenergic blocker, 5-alpha reductase inhibitor - Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms | Completed | Ain Shams University | 130 | 2025-12-30 | 2026-09-30 | |
| A Prospective Comparative Study Evaluating the Safety and Efficacy of Transurethral Thulium Fiber Laser, Holmium Laser and Bipolar Enucleation of Large Sized Prostate Thulium Fiber Laser Enucleation of the Prostate (ThuFLEP), Holmium Laser Enucleation of the Prostate (HoLEP), Bipolar Transurethral Enucleation of the Prostate (B-TUEP) - Benign Prostatic Hyperplasia (BPH), Lower Urinary Tract Symptom | Not applicable | Recruiting | Tanta University | 90 | 2025-10-21 | 2026-06-05 |
Showing 20 of 227. Sign in to see all of them.
Urethral Neoplasms (95) · Urinary Bladder Neoplasms (89) · Urethral Stricture (67) · Urinary Bladder Neck Obstruction (46) · Ureteral Neoplasms (41) · Carcinoma, Transitional Cell (24) · Prostatic Hyperplasia (22) · Lower Urinary Tract Symptoms (18) · Prostatic Neoplasms (18) · Carcinoma, Renal Cell (13) · Neoplasms (12) · Penile Neoplasms (12) · Anus Neoplasms (11) · Testicular Neoplasms (11) · Vaginal Neoplasms (11)
Female Urogenital Diseases (227) · Female Urogenital Diseases and Pregnancy Complications (227) · Urogenital Diseases (227) · Male Urogenital Diseases (225) · Urologic Diseases (225) · Urinary Bladder Diseases (132) · Urethral Obstruction (112) · Neoplasms by Site (99) · Urogenital Neoplasms (97) · Urologic Neoplasms (94) · Neoplasms (90) · Genital Diseases (56) · Pathological Conditions, Signs and Symptoms (54) · Genital Diseases, Male (48)
Gemcitabine (25) · Cisplatin (18) · Carboplatin (10) · Paclitaxel (10) · Docetaxel (6) · Doxorubicin (6) · Nivolumab (6) · Specimen Handling (6) · Magnetic Resonance Spectroscopy (5) · pembrolizumab (5) · Fluorouracil (4) · Methotrexate (4) · Radiotherapy (4) · Transurethral Resection of Prostate (4) · Vinblastine (4)
National Cancer Institute (NCI) (19) · M.D. Anderson Cancer Center (9) · Ain Shams University (6) · Eastern Cooperative Oncology Group (6) · SWOG Cancer Research Network (6) · University Hospital, Ghent (6) · National Taiwan University Hospital (5) · Urotronic Inc. (5) · European Organisation for Research and Treatment of Cancer - EORTC (4) · Al-Azhar University (3) · Astellas Pharma Inc (3) · Baylor College of Medicine (3) · Cardiff University (3) · Eli Lilly and Company (3) · Wake Forest University Health Sciences (3)
United States (119) · Egypt (16) · United Kingdom (16) · Belgium (13) · Canada (13) · Spain (13) · France (11) · Italy (11) · Israel (10) · Germany (9) · Netherlands (9) · Poland (8) · South Korea (7) · Turkey (Türkiye) (7) · China (6)
Bruce J. Roth, MD (3) · Ho-Hsiung Lin, PhD (3) · Nicolaas Lumen (3) · Wesley Verla (3) · Andrea B Apolo (2) · Andrea B Apolo, M.D. (2) · Arlene Siefker-Radtke, MD (2) · Daniel P. Petrylak, MD (2) · Dean F. Bajorin, MD (2) · Joaquim Bellmunt, MD, PhD (2) · Robert Dreicer (2) · Robert Dreicer, MD, FACP (2) · Sean Elliott, MD (2)
PMID 28754926, PMID 15540753, PMID 16804634, PMID 19937315, PMID 19949018, PMID 22002018, PMID 22415792, PMID 23722818, PMID 34854748, PMID 35031545, PMID 11001674, PMID 12448661, PMID 12767086, PMID 15073851, PMID 15541123, PMID 15911238, PMID 15989095, PMID 1607913, PMID 16080084, PMID 16330205, PMID 17437780, PMID 17617144, PMID 18024869, PMID 18459175, PMID 18470481, PMID 18501081, PMID 18685414, PMID 18758208, PMID 19173237, PMID 19269798, PMID 19371909, PMID 19786668, PMID 19941278, PMID 19967749, PMID 20068553, PMID 20554319, PMID 21288838, PMID 21315996, PMID 21337440, PMID 21374748, PMID 21413041, PMID 22162575, PMID 22370319, PMID 22480131, PMID 22611164, PMID 22819172, PMID 22831853, PMID 23223595, PMID 23329066, PMID 23376148
U10CA032102 (6), U10CA031946 (4), P30CA016672 (3), U10CA180821 (3), P50CA091846 (2), U10CA021115 (2), UM1CA186717 (2), 2014 (1), 2015 (1), 2017 (1), K12DK083021 (1), N01CM00038 (1), N01CM62201 (1), N01CM62205 (1), N01CM62209 (1)