47 completed, 28 unknown, 13 recruiting, 10 not yet recruiting. 54 Not applicable, 11 Phase 2, 10 Phase 3, 10 Phase 4, 7 Phase 1.
Follow Urethral Obstruction: new trials by email Literature Review of Urethral Obstruction trials Research Report on Urethral Obstruction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Feasibility Study of Autologous Engineered Urethral Constructs for the Treatment of Strictures Autologous Engineered Urethral Construct - Urologic Diseases, Male Urogenital Diseases | Phase 1 | Recruiting | Wake Forest University Health Sciences | 10 | 2027-01-01 | 2026-07-28 |
| High Intensity Focused Ultrasound (HIFU) Ablation for Treatment of Prostate Tissue in Bladder Outlet Obstruction High Intensity Focused Ultrasound - Bladder Outlet Obstruction, BPH | Not applicable | Not yet recruiting | Icahn School of Medicine at Mount Sinai | 17 | 2026-11-01 | 2026-10-09 |
| REDUCER Trial (TXA in Urethroplasty) Tranexamic Acid, Urethroplasty - Urethral Stricture, Urethral Diseases | Phase 4 | Not yet recruiting | Amjad Alwaal, MD, MSc, FRCSC, FACS | 40 | 2026-09-01 | 2026-08-13 |
| Comparison Between Excision And Primary Anastomosis Urethroplasty And Tunica Vaginalis Graft Urethroplasty. Excision and Primary Anastomosis Urethroplasty, Tunica Vaginalis Graft Urethroplasty - Urethral Stricture, Erectile Dysfunction | Not applicable | Not yet recruiting | Sahiwal medical college sahiwal | 94 | 2026-08-01 | 2026-08-05 |
| Intraoperative Lidocaine or Dexmedetomidine for Postoperative Pain Modulation After Urethral Reconstruction. Perioperative lidocaine infusion, Perioperative dexmedetomidine infusion, Perioperative placebo infusion - Urethral Stricture | Not applicable | Recruiting | Centre of Postgraduate Medical Education | 80 | 2026-07-07 | 2026-10-09 |
| Thulium Laser Enucleation With Bladder Neck Incision for Small-Volume Benign Prostatic Hyperplasia Thulium Laser Enucleation of the Prostate Combined With Bladder Neck Incision, Thulium Laser Enucleation of the Prostate, Transurethral Resection of the Prostate - Benign Prostatic Hyperplasia, Bladder Outlet Obstruction | Not applicable | Not yet recruiting | Chinese PLA General Hospital | 932 | 2026-07-01 | 2026-07-21 |
| Comparison of Concurrent Endoscopic Prostate Surgery With Botox-A Injection and Postoperative Medical Therapy in BPH Patients With Overactive Bladder Symptoms Urinary Bladder, Overactive, Prostatic Hyperplasia, Benign | Active not recruiting | Taksim Egitim ve Arastirma Hastanesi | 70 | 2026-04-01 | 2026-04-28 | |
| A Comparative Study of the Antibacterial Effects of Two Preoperative Hair Removal Methods in Male Patients With Urethral Stricture Wiping with wet wipes containing 2% chlorhexidine gluconate (CHG). - Urethral Stricture | Not applicable | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 40 | 2026-04-01 | 2026-04-02 |
| Urinary CTGF in Benign Prostatic Obstruction None-placebo - Benign Prostatic Hyperplasia, Bladder Outlet Obstruction | Not yet recruiting | Tarik Emre Sener | 50 | 2026-04-01 | 2026-02-18 | |
| Urethral Resistive Index (URI): A New Parameter for Diagnosing Urethral Obstruction Uroflowmetry with URI Calculation - Urethral Stricture | Recruiting | Ankara City Hospital Bilkent | 60 | 2026-02-10 | 2026-04-06 | |
| Effect of Catheter Duration on Prostate Laser Enucleation Surgery Outcomes in Patients With Urinary Retention Laser Enucleation of the Prostate (HoLEP, ThuLEP, ThuFLEP) - Urinary Retention, Benign Prostate Obstruction (BPO) | Recruiting | Eskişehir Osmangazi University Medicine Faculty Hospital | 54 | 2026-02-04 | 2026-09-11 | |
| The Impact of Age and Sex on Anticipated and Experienced Pain in First-Time Outpatient Flexible Cystoscopy Urethral Stricture, Bladder (Urothelial, Transitional Cell) Cancer | Not yet recruiting | Kayseri Education and Research Hospital | 150 | 2026-02-01 | 2026-01-29 | |
| The Effects of Holmium Laser Enucleation and Thulium Laser Enucleation on Continence, Urethral Stricture, and Sexual Function in Benign Prostatic Hyperplasia Benign Prostate Obstruction (BPO) | Not yet recruiting | TC Erciyes University | 200 | 2026-02-01 | 2026-01-12 | |
| Predictors of Trifecta Achievement After HoLEP Transurethral Holmium Laser Enuclation of the Prostate - HoLEP, Trifecta Achievement | Not applicable | Not yet recruiting | Ondokuz Mayıs University | 604 | 2026-01-30 | 2026-02-24 |
| Risk of Recurrent Urethral Stricture After Treatment With Paclitaxel-Coated Dilatation Balloon (Optilume) Compared With Non-coated Dilatation Balloon Optilume, UroMax Ultra - Urethral Stricture | Phase 4 | Recruiting | Vastra Gotaland Region | 230 | 2026-01-16 | 2026-01-16 |
| Holmium Laser Versus Cold Knife Treatment in Urethral Strictures holmium laser, cold knife - Stricture Urethra, Holmium Laser | Not applicable | Completed | Shahida Islam Medical Complex | 60 | 2026-01-15 | 2026-04-21 |
| LishitonglinUS-01 Trial Lishitonglin Formula granules, Oral placebo medication formulated as granules - Urethra Stricture | Phase 2 | Active not recruiting | Peking University First Hospital | 120 | 2026-01-09 | 2026-08-17 |
| Ultrasound IPP to Predict Response to Medical Therapy in LUTS/BPH Transabdominal ultrasound measurement of intravesical prostatic protrusion, Alpha-adrenergic blocker, 5-alpha reductase inhibitor - Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms | Completed | Ain Shams University | 130 | 2025-12-30 | 2026-09-30 | |
| A Prospective Comparative Study Evaluating the Safety and Efficacy of Transurethral Thulium Fiber Laser, Holmium Laser and Bipolar Enucleation of Large Sized Prostate Thulium Fiber Laser Enucleation of the Prostate (ThuFLEP), Holmium Laser Enucleation of the Prostate (HoLEP), Bipolar Transurethral Enucleation of the Prostate (B-TUEP) - Benign Prostatic Hyperplasia (BPH), Lower Urinary Tract Symptom | Not applicable | Recruiting | Tanta University | 90 | 2025-10-21 | 2026-06-05 |
| Platelet Rich Plasma Versus Mitomycin C Injection Following Visual Internal Urethrotomy in Urethral Stricture Visual internal urethrotomy followed by submucosal intralesional mitomycin C injection, Visual internal urethrotomy followed by submucosal Platlet Rich Plasma injection - Urethral Stricture | Phase 3 | Completed | Ain Shams University | 50 | 2025-08-01 | 2026-10-20 |
Showing 20 of 116. Sign in to see all of them.
Urethral Stricture (67) · Urinary Bladder Neck Obstruction (46) · Prostatic Hyperplasia (22) · Lower Urinary Tract Symptoms (18) · Urinary Bladder, Underactive (5) · Urinary Bladder, Overactive (4) · Urinary Incontinence (4) · Hypospadias (3) · Constriction, Pathologic (2) · Cystocele (2) · Male Urogenital Diseases (2) · Pain, Postoperative (2) · Prostatic Neoplasms (2) · Spinal Cord Injuries (2)
Female Urogenital Diseases (116) · Female Urogenital Diseases and Pregnancy Complications (116) · Urogenital Diseases (116) · Urethral Diseases (115) · Male Urogenital Diseases (114) · Urologic Diseases (114) · Urinary Bladder Diseases (45) · Pathological Conditions, Signs and Symptoms (40) · Signs and Symptoms (32) · Urological Manifestations (29) · Genital Diseases (28) · Genital Diseases, Male (27) · Prostatic Diseases (23) · Lower Urinary Tract Symptoms (11)
Transurethral Resection of Prostate (4) · Lasers, Solid-State (3) · Gabapentin (2) · Solifenacin Succinate (2) · Tamsulosin (2) · fexapotide (2) · 5-alpha Reductase Inhibitors (1) · Acetaminophen (1) · Adrenergic alpha-Antagonists (1) · Bupivacaine (1) · Calcium Dobesilate (1) · Celecoxib (1) · Chromogranins (1) · Conization (1) · Cystoscopy (1)
Ain Shams University (6) · University Hospital, Ghent (6) · National Taiwan University Hospital (5) · Urotronic Inc. (5) · Al-Azhar University (3) · Baylor College of Medicine (3) · Astellas Pharma Inc (2) · Mansoura University (2) · Menoufia University (2) · Northwestern University (2) · Nymox Corporation (2) · Samsung Medical Center (2) · Tanta University (2) · University of California, San Francisco (2) · University of Roma La Sapienza (2)
United States (34) · Egypt (16) · Belgium (9) · Israel (6) · Turkey (Türkiye) (6) · China (5) · Taiwan (5) · United Kingdom (5) · Poland (4) · Canada (3) · Italy (3) · Russia (3) · South Korea (3) · Spain (3) · Switzerland (3)
Ho-Hsiung Lin, PhD (3) · Nicolaas Lumen (3) · Wesley Verla (3) · Sean Elliott, MD (2) · Ahmed El-Assmy (1) · Ahmed Elshal, MD (1) · Ahmed Fahim, professor (1) · Ahmed M Reyad, MD (1) · Alexander Schultz, MD (1) · Alexis Te, MD (1) · Amjad Alwaal, MD, MSc, FACS (1) · Andrey A Pulin, MD, PhD (1) · Andrey Vinarov, Dr., Prof. (1) · Andrey Z Vinarov, MD, PhD, Prof (1)
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K12DK083021 (1)