104 completed, 67 recruiting, 48 not yet recruiting, 30 active not recruiting. 125 Not applicable, 39 Phase 1, 28 Phase 2, 18 Phase 3, 17 Phase 4.
Follow Type 2 Diabetes Mellitus (T2DM): new trials by email Literature Review of Type 2 Diabetes Mellitus (T2DM) trials Research Report on Type 2 Diabetes Mellitus (T2DM)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Simplified Total-body Resistance Exercise for Muscular Hypertrophy for Diabetic Population (D-STORM) D-STORM Resistance Training Programme, usual care - Type 2 Diabetes Mellitus (T2DM), Sarcopenia | Not applicable | Not yet recruiting | Universiti Teknologi Mara | 56 | 2027-01-01 | 2026-06-25 |
| Endoscopic Band Ligation for Type 2 Diabetes Mellitus (ENDOBAND-DM) Endoscopic Band Ligation (ENDOBAND-DM) - Type 2 Diabetes Mellitus (T2DM) | Not applicable | Not yet recruiting | El Katib Hospital | 10 | 2027-01-01 | 2026-09-10 |
| Digital Self-Management Education and Support for Young Adults With Type 2 Diabetes (DSMESYAT2DM) Digital Nurse-Led DSMES Program, Usual Care Plus Standard Digital Education - Type 2 Diabetes Mellitus (T2DM), Diabetes-related Distress | Not applicable | Not yet recruiting | Recep Turan | 72 | 2026-12-16 | 2026-09-03 |
| Study on Improving Blood Glucose Homeostasis With Dorzagliatin Tablets in the Treatment of Type 2 Diabetes Mellitus Patients With Moderate to Severe Chronic Renal Insufficiency Dorzagliatin, Linagliptin - Type 2 Diabetes Mellitus (T2DM), Chronic Renal Insufficiency | Not applicable | Withdrawn | Sun Yat-sen University | 2026-12-01 | 2026-10-16 | |
| HMB Plus Vitamin D to Preserve Muscle in Older Adults Starting Semaglutide Calcium-HMB Plus Vitamin D3, Matching placebo - Type 2 Diabetes Mellitus (T2DM), Sarcopenia | Phase 2 | Not yet recruiting | Vanderbilt University Medical Center | 90 | 2026-12-01 | 2026-08-28 |
| Experience With the Use of Continuous Glucose Monitoring (CGM) Devices in People With Type 2 Diabetes Mellitus Patient Satisfaction, Continuous Glucose Monitoring | Not yet recruiting | Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina | 5 | 2026-10-01 | 2026-08-25 | |
| A Study to Evaluate the Efficacy and Safety of AD-233A, AD-233B, AD-233C and/or AD-233D Combination Therapy AD-233A, AD-233B, AD-233C - Type 2 Diabetes Mellitus (T2DM) | Phase 3 | Not yet recruiting | Addpharma Inc. | 354 | 2026-09-30 | 2026-09-16 |
| Effect of Digital-Supported Foot Care Education in Individuals With Type 2 Diabetes Digital-Supported Foot Care Education - Type 2 Diabetes Mellitus (T2DM) | Not applicable | Not yet recruiting | Siirt University | 90 | 2026-09-20 | 2026-09-10 |
| Efficacy and Safety of Mazdutide in Patients With Type 2 Diabetes Mellitus and Moderate to Severe Nonalcoholic Fatty Liver Disease Previously Treated With Semaglutide Mazdutide(Dual GLP-1R/GCGR Agonist), Semaglutide (1 Mg Dose) - Type 2 Diabetes Mellitus (T2DM), Nonalcoholic Fatty Liver Disease (NAFLD) With History of Diabetes Melitus | Not applicable | Not yet recruiting | Tianjin Medical University | 72 | 2026-09-15 | 2026-07-20 |
| Investigating Vascular Properties of HEMI and SPG Signals in Individuals With or at Risk for Chronic Kidney Disease HEMI device, SPG-NINOX device - Chronic Kidney Disease, Hypertension (HTN) | Not applicable | Not yet recruiting | Institut National de la Santé Et de la Recherche Médicale, France | 165 | 2026-09-15 | 2026-07-31 |
| THE EFFECT OF BITTER ORANGE (CITRUS AURANTIUM) OIL AROMATHERAPY ON SLEEP QUALITY AND FATIGUE LEVELS bitter orange oil group - Type 2 Diabetes Mellitus (T2DM) | Not applicable | Not yet recruiting | Uludag University | 100 | 2026-09-15 | 2026-08-10 |
| Multilingual Voice Calls to Adjust Long-Acting Insulin for Adults With Type 2 Diabetes and Low Health Literacy in Pakistan Multilingual IVR-Supported Basal Insulin Titration, Standard Clinic-Based Basal Insulin Titration - Type 2 Diabetes Mellitus (T2DM), Hyperglycemia Due to Type 2 Diabetes Mellitus | Not applicable | Active not recruiting | Shifa International Hospital | 220 | 2026-09-10 | 2026-09-15 |
| Exocrine-Endocrine Pancreatic Crosstalk: Precision Pathways to Reframe Diabetes Pathophysiology Type 2 Diabetes Mellitus (T2DM), Chronic Pancreatitis | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 440 | 2026-09-01 | 2026-06-26 | |
| Effects of a Researcher-Designed Diabetes Self-Management App on Self-Management Obstacles, Self-Efficacy, and Physiological Indicators in Type 2 Diabetes Researcher-Designed Diabetes Self-Management Application - Type 2 Diabetes Mellitus (T2DM), Self-management | Not applicable | Not yet recruiting | Fu Jen Catholic University Hospital | 80 | 2026-09-01 | 2026-08-31 |
| Cardioprotective Effects of SGLT2 Inhibitors and GLP-1 Receptor Agonists in Korean Patients With Type 2 Diabetes Type 2 Diabetes Mellitus (T2DM), Cardiovascular Diseases | Not yet recruiting | Dongtan Sacred Heart Hospital | 100 | 2026-09-01 | 2026-08-18 | |
| Phase III Trial of SGLT2 Inhibitor and Thiazolidinedione Fixed-Dose Combination vs. Monotherapy in Type 2 Diabetes Patients on Metformin Fixed-dose combination of SGLT2 inhibitor and thiazolidinedione, Control Group 1 Intervention - SGLT2 inhibitor monotherapy, Control Group 2 Intervention - Thiazolidinedione monotherapy - Type 2 Diabetes Mellitus (T2DM) | Phase 3 | Withdrawn | Eurofarma Laboratorios S.A. | 2026-09-01 | 2025-12-18 | |
| BALANCE-DM2 Study of Bofanglutide in Adults With Type 2 Diabetes Bofanglutide, Semaglutide - Type 2 Diabetes Mellitus (T2DM) | Phase 3 | Not yet recruiting | Carnot Laboratories | 374 | 2026-09-01 | 2026-06-05 |
| Using Continuous Glucose Monitoring to Quantify the Effects of NOURISH's Culturally Modified Meals on Asian Americans With Type 2 Diabetes NOURISH Diet, Self-Selected Diet (Control) - Type 2 Diabetes Mellitus (T2DM), Type 2 Diabetes | Not applicable | Recruiting | Stanford University | 30 | 2026-08-31 | 2026-09-28 |
| CEEEC-II: A 12-Week Physical and Cognitive Enrichment Extension Study in Older Stroke Survivors With Multimorbidity Physical Enrichment, Cognitive Enrichment - Stroke, Hypertension | Not applicable | Not yet recruiting | Duke Kunshan University | 365 | 2026-08-31 | 2026-08-21 |
| Goal-Directed Therapy to Reduce Kidney and Cardiovascular Risk in Diabetic Kidney Disease (GOLD-STANDARD) Early goal-directed Cardio-Kidney-Metabolic (CKM) care, Standard care (Comparison arm) - Diabetic Kidney Disease (DKD), Type 2 Diabetes Mellitus (T2DM) | Not applicable | Recruiting | Sunnybrook Health Sciences Centre | 100 | 2026-08-26 | 2026-09-04 |
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Diabetes Mellitus, Type 2 (269) · Obesity (38) · Diabetes Mellitus (25) · Overweight (19) · Hypertension (16) · Renal Insufficiency, Chronic (14) · Insulin Resistance (13) · Cardiovascular Diseases (9) · Metabolic Syndrome (9) · Hyperglycemia (8) · Diabetes Mellitus, Type 1 (7) · Prediabetic State (7) · Non-alcoholic Fatty Liver Disease (6) · Atherosclerosis (5) · Coronary Artery Disease (5)
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