4 recruiting. 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Recruiting 4 |
Follow Tuberculosis, Central Nervous System: new trials by email Literature Review of Tuberculosis, Central Nervous System trials Research Report on Tuberculosis, Central Nervous System
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| BPaLMZ for TB Meningitis BPaLMZ Regimen - Tuberculous Meningitis, HIV | Phase 2 | Recruiting | David Boulware | 312 | 2026-07-28 | 2026-10-16 |
| Adjunctive Doxycycline for Central Nervous System Tuberculosis Doxycycline, Placebo, Anti Tuberculosis Drug - Tuberculosis, Meningeal, Tuberculosis; Meningitis (Etiology) | Phase 2 | Recruiting | National University Hospital, Singapore | 200 | 2025-08-21 | 2026-06-01 |
| Trial of a Six-Month Regimen of High-Dose Rifampicin, High-Dose Isoniazid, Linezolid, and Pyrazinamide Versus a Standard Nine-Month Regimen for the Treatment of Adults and Adolescents With Tuberculous Meningitis Rifampicin (RIF), Isoniazid (INH), Linezolid (LZD) - Tuberculous Meningitis | Phase 2 | Recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 330 | 2023-12-07 | 2026-06-02 |
| Tnf Inhibitors to Reduce Mortality in HIV-1 Infected PAtients With Tuberculosis meNIngitis Adalimumab Injection - Tuberculous Meningitis, HIV I Infection | Phase 2 | Recruiting | ANRS, Emerging Infectious Diseases | 130 | 2023-04-11 | 2025-12-15 |
Tuberculosis, Meningeal (4) · Meningitis (2) · Tuberculosis (2) · Central Nervous System Diseases (1) · Latent Tuberculosis (1) · Meningoencephalitis (1)
Actinomycetales Infections (4) · Bacterial Infections (4) · Bacterial Infections and Mycoses (4) · Central Nervous System Bacterial Infections (4) · Central Nervous System Infections (4) · Gram-Positive Bacterial Infections (4) · Infections (4) · Meningitis, Bacterial (4) · Mycobacterium Infections (4) · Nervous System Diseases (4) · Neuroinflammatory Diseases (4) · Tuberculosis, Extrapulmonary (4) · Central Nervous System Diseases (3) · Meningitis (2)
Adalimumab (1) · Antitubercular Agents (1) · Doxycycline (1) · Ethambutol (1) · Isoniazid (1) · Linezolid (1) · Pyrazinamide (1) · Rifampin (1)
ANRS, Emerging Infectious Diseases (1) · David Boulware (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · National University Hospital, Singapore (1)
Brazil (2) · India (1) · Indonesia (1) · Kenya (1) · Malawi (1) · Malaysia (1) · Mexico (1) · Mozambique (1) · Peru (1) · Philippines (1) · Singapore (1) · South Africa (1) · Tanzania (1) · Thailand (1) · Uganda (1)