5 completed, 3 recruiting, 2 unknown, 1 not yet recruiting. 3 Not applicable, 3 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Completed 1, Unknown 1, Withdrawn 1 |
| Phase 2 | 3 | Completed 2, Recruiting 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
Follow Meningoencephalitis: new trials by email Literature Review of Meningoencephalitis trials Research Report on Meningoencephalitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pain Phenotyping of Rheumatic Diseases - An Observational Study Bedside quantitative sensory testing - Rheumatic Diseases, Lupus Erythematosus, Systemic | Not yet recruiting | National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | 225 | 2026-11-02 | 2026-10-28 | |
| Adjunctive Doxycycline for Central Nervous System Tuberculosis Doxycycline, Placebo, Anti Tuberculosis Drug - Tuberculosis, Meningeal, Tuberculosis; Meningitis (Etiology) | Phase 2 | Recruiting | National University Hospital, Singapore | 200 | 2025-08-21 | 2026-06-01 |
| Lupus Landmark Study: A Prospective Registry and Biorepository Systemic Lupus Erythematosus (SLE), Lupus Nephritis | Recruiting | Lupus Research Alliance | 3500 | 2023-06-28 | 2026-04-15 | |
| Optimal Encephalitis/Meningitis Roadmap Via Precise Diagnosis and Treatment Types of etiological diagnostic methods - Encephalitis, Meningitis | Not applicable | Unknown | Wen-hong Zhang | 484 | 2021-04-14 | 2021-07-01 |
| Swiss Pediatric Inflammatory Brain Disease Registry (Swiss-Ped-IBrainD) Optic Neuritis, Transverse Myelitis | Recruiting | University of Bern | 500 | 2020-04-14 | 2024-12-16 | |
| EG-501 for Cognitive Impairment in Neuropsychiatric SLE (NPSLE): Efficacy and Safety Study Placebo, EG-501 - Neuropsychiatric Systemic Lupus Erythematosus, Systemic Lupus Erythematosus (SLE) | Phase 2 | Completed | Evergreen Therapeutics, Inc. | 131 | 2018-08-23 | 2025-12-15 |
| Research for Angiostrongylus Cantonensis and Costaricensis in French West Indies and French Guiana Parasitic serologies, Biopsy - Angiostrongylosis, Hypereosinophilia | Unknown | University Hospital Center of Martinique | 20 | 2018-04-03 | 2020-12-11 | |
| Treatment With Tamoxifen in Cryptococcal Meningitis Tamoxifen, Amphotericin B, Fluconazole - Meningitis Streptococcal, Hiv | Phase 2 | Completed | Oxford University Clinical Research Unit, Vietnam | 50 | 2017-10-10 | 2019-12-02 |
| Investigating the Role of Early Intravenous Immunoglobulin Treatment for Children With Encephalitis Immunoglobulins, Intravenous (Privigen), Placebo - Encephalitis | Phase 3 | Completed | University of Oxford | 18 | 2016-01-01 | 2024-03-04 |
| Prevalence of Pathogens in Cerebrospinal Fluid Obtained From Emergency Department Patients no intervention - Meningoencephalitis, Other Syndromes Requiring Lumbar Puncture in Emergency Department | Terminated | Olive View-UCLA Education & Research Institute | 1000 | 2014-04-01 | 2022-04-20 | |
| Magnetic Resonance Spectroscopy, Perfusion, and Diffusion Tensor Imaging in Neuropsychiatric Lupus Magnetic Resonance Angiography (MRA), Magnetic resonance imaging, MRA - Neuropsychiatric Systemic Lupus Erythematosus | Not applicable | Completed | University of Michigan | 66 | 2008-03-01 | 2015-12-14 |
| Phase Ib Study of SC Milatuzumab in SLE milatuzumab, Placebo - Lupus Erythematosus, Cutaneous, Lupus Erythematosus, Discoid | Phase 1 | Completed | Gilead Sciences | 22 | 2007-01-01 | 2021-08-19 |
| Libman-Sacks Endocarditis as a Cause of Neuropsychiatric Systemic Lupus Erythematosus Clinical and laboratory evaluations, transesophageal echocardiography, carotid duplex, transcranial duplex, and magnetic resonance of the brain - Systemic Lupus Erythematosus | Not applicable | Withdrawn | University of New Mexico | 2006-08-01 | 2024-01-10 |
Lupus Vasculitis, Central Nervous System (7) · Lupus Erythematosus, Systemic (5) · Encephalitis (3) · Meningitis (3) · Lupus Nephritis (2) · Acquired Immunodeficiency Syndrome (1) · Angiostrongyliasis (1) · Anti-N-Methyl-D-Aspartate Receptor Encephalitis (1) · Arthritis (1) · Arthritis, Rheumatoid (1) · Autoimmune Diseases of the Nervous System (1) · Central Nervous System Diseases (1) · Central Nervous System Infections (1) · Cognitive Dysfunction (1)
Brain Diseases (13) · Central Nervous System Viral Diseases (13) · Infections (13) · Nervous System Diseases (13) · Neuroinflammatory Diseases (13) · Central Nervous System Diseases (12) · Central Nervous System Infections (12) · Encephalitis (10) · Meningitis (10) · Immune System Diseases (8) · Autoimmune Diseases (7) · Cardiovascular Diseases (7) · Cerebrovascular Disorders (7) · Connective Tissue Diseases (7)
Amphotericin B (1) · Antitubercular Agents (1) · Biopsy (1) · Diffusion Tensor Imaging (1) · Doxycycline (1) · Fluconazole (1) · Immunoglobulins (1) · Immunoglobulins, Intravenous (1) · Laboratories (1) · Magnetic Resonance Spectroscopy (1) · Tamoxifen (1) · milatuzumab (1)
Evergreen Therapeutics, Inc. (1) · Gilead Sciences (1) · Lupus Research Alliance (1) · National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) (1) · National University Hospital, Singapore (1) · Olive View-UCLA Education & Research Institute (1) · Oxford University Clinical Research Unit, Vietnam (1) · University Hospital Center of Martinique (1) · University of Bern (1) · University of Michigan (1) · University of New Mexico (1) · University of Oxford (1) · Wen-hong Zhang (1)
United States (7) · Canada (1) · China (1) · France (1) · Indonesia (1) · Malaysia (1) · Singapore (1) · Switzerland (1) · United Kingdom (1) · Vietnam (1)
Alfred Kim, MD, PhD (1) · Andrew J Pollard, FRCPCH, PhD (1) · Arezou Khosroshahi, MD (1) · Carlos A Roldan, M.D. (1) · Jeremy Day, MD (1) · Leslie J. Crofford, M.D. (1) · Pia Maly Sundgren, MD, PHD (1) · Pia Maly Sundgren, MD-PHD (1) · Sam Lim, MD, MPH (1) · Sandra Bigi, PD MD (1) · Sarfaraz A Hasni, M.D. (1) · William Wegener, PhD, MD (1)
PMID 20813797, PMID 30801037, PMID 34581270, PMID 34998377, PMID 37945292, PMID 42521601
2019 (1), U01CK000176 (1)