3 completed, 1 not yet recruiting, 1 terminated, 1 unknown. 6 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 6 | Completed 3, Not yet recruiting 1, Terminated 1, Unknown 1 |
Follow Trauma Injury: new trials by email Literature Review of Trauma Injury trials Research Report on Trauma Injury
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Multicenter Study to Evaluate the Safety and Efficacy of SYMVESS™ in a Real World Setting in Patients With Extremity Arterial Injury Requiring Urgent Repair Acellular Tissue Engineered Vessel - Vascular Injury, Arterial Injury | Phase 4 | Not yet recruiting | Humacyte, Inc. | 125 | 2026-09-01 | 2026-08-13 |
| Dronabinol On the Pain Experience Standard of Care (acetaminophen +naproxen +gabapentin + as needed oxycodone or Tramadol), Dronabinol - Trauma Injury | Phase 4 | Terminated | The University of Texas Health Science Center, Houston | 484 | 2023-07-27 | 2025-06-11 |
| Patient-Titrated Automated Intermittent Boluses of Local Anesthetic vs. a Continuous Infusion Via a Perineural Catheter for Postoperative Analgesia Continuous Infusion of ropivacaine 0.2%, Titratable Automated Intermittent Boluses of ropivacaine 0.2% - Pain, Acute Postoperative, Trauma Injury | Phase 4 | Completed | University of California, San Diego | 60 | 2022-03-22 | 2026-08-24 |
| Ketamine for Acute Pain Management After Trauma Ketamine plus usual care, Usual Care - Trauma Injury, Pain | Phase 4 | Completed | The University of Texas Health Science Center, Houston | 305 | 2020-07-01 | 2023-04-21 |
| Liposomal Bupivacaine Intercostal Nerve Block vs Thoracic Epidural for Regional Analgesia in Multiple Rib Fractures Bupivacaine Liposome Injection, Bupivacaine - Trauma, Trauma Injury | Phase 4 | Unknown | Chadrick Evans | 258 | 2018-08-29 | 2020-03-09 |
| Effect of Toradol on Post-operative Foot and Ankle Healing Ketorolac, No ketorolac - Ankle Fractures, Trauma Injury | Phase 4 | Completed | Rothman Institute Orthopaedics | 128 | 2016-08-01 | 2018-11-01 |
Accidental Injuries (6) · Wounds and Injuries (3) · Acute Pain (1) · Ankle Fractures (1) · Pain (1) · Pain, Postoperative (1) · Vascular System Injuries (1)
Neurologic Manifestations (3) · Pathological Conditions, Signs and Symptoms (3) · Signs and Symptoms (3) · Wounds and Injuries (3) · Pain (2) · Ankle Injuries (1) · Cardiovascular Diseases (1) · Fractures, Bone (1) · Leg Injuries (1) · Pathologic Processes (1) · Postoperative Complications (1) · Vascular Diseases (1)
Bupivacaine (1) · Dronabinol (1) · Ketamine (1) · Ketorolac (1) · Ketorolac Tromethamine (1) · Standard of Care (1) · Tramadol (1)
The University of Texas Health Science Center, Houston (2) · Chadrick Evans (1) · Humacyte, Inc. (1) · Rothman Institute Orthopaedics (1) · University of California, San Diego (1)
United States (4)
Brian M Ilfeld, MD, MS (1) · Chadrick R Evans, MD (1) · John Harvin, MD, FACS (1) · John P Harvin, MD (1) · Steven Raikin, MD (1)
PMID 12576361, PMID 16625122, PMID 19247744, PMID 19359920, PMID 20048659, PMID 21256488, PMID 21716105, PMID 22695321, PMID 23403516, PMID 23614099, PMID 24108252, PMID 24458051, PMID 25210700, PMID 25527168, PMID 25683770, PMID 25912739, PMID 26204387, PMID 26507422, PMID 26604819, PMID 27533913, PMID 35897081, PMID 38689402