43 completed, 27 unknown, 12 recruiting, 5 not yet recruiting. 46 Not applicable, 12 Phase 2, 9 Phase 1, 2 Phase 4, 1 Early Phase 1.
Follow Tracheal Diseases: new trials by email Literature Review of Tracheal Diseases trials Research Report on Tracheal Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Voice Quality Analysis of Patients With Laryngotracheal Stenosis Voice Biomarker Screening Too - Idiopathic Subglottic Tracheal Stenosis | Not yet recruiting | Johns Hopkins University | 100 | 2027-01-01 | 2026-07-13 | |
| Feasibility of Tracheobronchial Reconstruction Using Allogenic Aortic Patch in Children Cryopreserved aorta - Trachea Diseases, Tracheal Stenosis | Not applicable | Enrolling by invitation | National Taiwan University Hospital | 5 | 2026-12-01 | 2026-08-17 |
| Laryngotracheal Lesions in Adults With Long-Term Tracheostomy Standardized Three-Station Bronchoscopy - Laryngotracheal Lesions, Tracheostomy Complications | Not yet recruiting | Hongying Jiang, MD | 220 | 2026-12-01 | 2026-10-28 | |
| The Role of Ultrasonographic Tracheal Measurements in Predicting Hypoxemia During Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration TRACHEAL DIAMETER MEASUREMENT, Hypoxemia - ENDOBRONCHIAL ULTRASOUND - TRANSBRONCHIAL NEEDLE ASPIRATION, Hypoxemia | Not yet recruiting | Ankara Ataturk Sanatorium Training and Research Hospital | 300 | 2026-11-20 | 2026-11-04 | |
| Combination Bevacizumab and PRGN-2012 in Adults With Recurrent Respiratory Papillomatosis (RRP) PRGN-2012, Bevacizumab - Respiratory Recurrent Papillomatosis (RRP), Human Papillomavirus (HPV) | Phase 2 | Not yet recruiting | National Cancer Institute (NCI) | 50 | 2026-11-11 | 2026-11-06 |
| Transcriptomic Profile Changes in Benign Tracheal Stenosis: Wedge Resection vs. Radial Incision Bronchoscopy, carbon dioxide (CO2) laser wedge resection, Radial incision with dilation - Tracheal Stenosis | Not applicable | Recruiting | University of Maryland, Baltimore | 40 | 2026-05-01 | 2026-08-20 |
| Paclitaxel-Coated Pulmonary Balloon for the Treatment of Benign Central Airway Stenosis The Airiver Pulmonary drug-coated balloon (DCB) dilation, Commercial airway balloon dilation - Adult Subjects With Symptomatic Benign Airway Obstruction, Adult Benign Central Airway Stenosis | Not applicable | Recruiting | Airiver Medical, Inc. | 200 | 2026-02-24 | 2026-06-18 |
| Feasibility of Tracheobronchial Defect Reconstruction Using Allogenic Aortic Patch Cryopreserved aortic patch - Trachea Diseases, Airway Remodeling | Not applicable | Recruiting | National Taiwan University Hospital | 10 | 2025-09-15 | 2026-06-12 |
| RNA Sequencing of Discarded Tracheal Stenosis Tissue to Characterize Cellular and Molecular Pathogenesis Biopsy or surgery - Tracheal Stenosis, Subglottic Stenosis | Recruiting | University of Maryland, Baltimore | 10 | 2025-09-11 | 2025-12-02 | |
| CT-Based Scoring System to Predict Surgical Need in Tracheal Stenosis (TSMAS Study) CT-Based Morphologic and Attenuation Scoring - Tracheal Stenosis | Completed | Ondokuz Mayıs University | 69 | 2025-09-01 | 2026-10-20 | |
| Spray Cryotherapy for the Management of Benign Central Airway Stenosis (Cryo-BAS) Spray cryo therapy, Standard of Care (SOC) - Stenosis of Trachea | Phase 2 | Recruiting | Beth Israel Deaconess Medical Center | 50 | 2025-06-02 | 2025-07-28 |
| Slide Tracheoplasty Versus Tracheal Resection Anastomosis in Acquired Tracheal Stenosis Slide tracheoplasty, Tracheal resection anastomosis - Tracheal Stenosis, Subglottic Stenosis | Not applicable | Recruiting | Mansoura University Hospital | 30 | 2025-05-01 | 2025-09-25 |
| Tubeless Tracheal and Carinal Reconstruction non-intubated tracheal and carinal reconstruction, intubated tracheal and carinal reconstruction - Tracheal Disease, Airway Disease | Not applicable | Recruiting | Shuben Li | 176 | 2025-03-26 | 2025-07-15 |
| Bioresorbable Airway Splint Pivotal Clinical Trial Bioresorbable Tracheobronchial Splint - Tracheobronchomalacia | Not applicable | Recruiting | University of Michigan | 35 | 2025-01-07 | 2026-01-21 |
| Camera-based Endoscopy Allows Spontaneous Breathing Diagnostic Management in Neonates With Tracheoesophageal Fistula tracheoscopy performed with rigid optical tracheoscopy, flexible video endoscopy of trachea - Tracheoesophageal Fistula, Esophageal Atresia With Tracheo-esophageal Fistula | Recruiting | Papa Giovanni XXIII Hospital | 60 | 2024-10-01 | 2026-07-07 | |
| Primary Posterior Tracheopexy Prevents Tracheal Collapse Randomisation between the PPT- and no-PPT-group, Primary Posterior Tracheopexy, Preoperative tracheobronchoscopy - Oesophageal Atresia With Tracheo-Oesophageal Fistula, Tracheomalacia | Not applicable | Enrolling by invitation | UMC Utrecht | 78 | 2024-09-01 | 2025-03-30 |
| Enhancing Lung Health in Kids With Structural Lung Damage and Malformations: Azithromycin (AZI) for Airway Infection Prevention Azithromycin 40 MG/ML, Placebo - Tracheomalacia, Bronchopulmonary Dysplasia (BPD) | Phase 3 | Not yet recruiting | Copenhagen University Hospital, Rigshospitalet | 150 | 2024-09-01 | 2024-05-14 |
| The Novel Special Light for Endotracheal/Bronchial Lesions. Tracheal Disease, Bronchial Disease | Enrolling by invitation | Shanghai Chest Hospital | 400 | 2024-01-31 | 2025-06-25 | |
| Airway Microbiome Changes After Artificial Airway Exchange in Critically-ill Pediatric Patients. Suctioning of artificial airway - Tracheostomy, Endotracheal Tube | Unknown | Northwell Health | 50 | 2023-12-20 | 2024-01-17 | |
| Long-term Outcomes of Post-intubation Tracheal Stenosis; 7-year Follow-up Interventional Bronchoscopy - Tracheal Stenosis, Intensive Care Unit | Completed | Ankara Ataturk Sanatorium Training and Research Hospital | 76 | 2023-10-12 | 2023-12-01 |
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Tracheal Stenosis (41) · Tracheobronchomalacia (14) · Tracheoesophageal Fistula (12) · Tracheomalacia (9) · Esophageal Atresia (5) · Neoplasms (5) · Tracheitis (5) · COVID-19 (4) · Laryngeal Diseases (4) · Laryngostenosis (4) · Lung Neoplasms (4) · Pulmonary Disease, Chronic Obstructive (4) · Esophageal Neoplasms (3) · Esophageal atresia with or without tracheoesophageal fistula (3)
Respiratory Tract Diseases (102) · Pathological Conditions, Signs and Symptoms (36) · Congenital Abnormalities (32) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (32) · Musculoskeletal Abnormalities (22) · Musculoskeletal Diseases (22) · Skin and Connective Tissue Diseases (22) · Bronchial Diseases (21) · Cartilage Diseases (21) · Connective Tissue Diseases (21) · Lung Diseases (18) · Digestive System Diseases (16) · Gastrointestinal Diseases (16) · Pathologic Processes (16)
Dilatation (3) · Azithromycin (1) · Bethanechol (1) · Bevacizumab (1) · Biopsy (1) · Bronchoscopy (1) · Carbon Dioxide (1) · Carboplatin (1) · Combined Modality Therapy (1) · Continuous Positive Airway Pressure (1) · Cryotherapy (1) · Dexamethasone (1) · Everolimus (1) · Fluorouracil (1) · Hemodynamics (1)
Beth Israel Deaconess Medical Center (6) · National Taiwan University Hospital (4) · Johns Hopkins University (3) · Abbott (2) · Ankara Ataturk Sanatorium Training and Research Hospital (2) · Assistance Publique - Hôpitaux de Paris (2) · Assiut University (2) · Hamad Medical Corporation (2) · University College, London (2) · University of Cape Town (2) · University of Maryland, Baltimore (2) · Yonsei University (2) · Ain Shams University (1) · Airiver Medical, Inc. (1) · Alexandria University (1)
United States (27) · United Kingdom (9) · China (8) · Taiwan (6) · South Korea (5) · Turkey (Türkiye) (5) · Egypt (4) · Italy (4) · Canada (3) · Czechia (3) · France (3) · Belarus (2) · Brazil (2) · Germany (2) · Qatar (2)
Alexander Hillel, MD (3) · Adam Hloska, M.D. (2) · Jin-Shing Chen, MD, PhD (2) · Nabil Shallik, M.D. (2) · Adnan Majid, MD (1) · Ahmed Elshamy, MD (1) · Akram Amer, MD (1) · Ali I Musani, MD, FCCP (1) · Amarilio V Macedo, Postdoc (1) · Amel H Abo Elela, Prof (1) · Andrei Hancharou, Dr (1) · Andrei Y Hancharou, Dr (1) · Armin Ernst, M.D. FCCP (1) · Aviril Sepulveda (1) · Aynalem Bk Woldemichael, MSC (1)
PMID 10195521, PMID 10211806, PMID 11015501, PMID 11037646, PMID 11210089, PMID 11465176, PMID 11891439, PMID 12041622, PMID 12365653, PMID 12755310, PMID 13326155, PMID 14521526, PMID 15236902, PMID 15450579, PMID 1545649, PMID 1653092, PMID 16903645, PMID 16949978, PMID 17389159, PMID 17426218, PMID 17475599, PMID 17695689, PMID 17699133, PMID 17883582, PMID 17908656, PMID 18364264, PMID 1848465, PMID 18842912, PMID 19084420, PMID 20199237, PMID 20689914, PMID 20934755, PMID 21493699, PMID 21513991, PMID 21626712, PMID 21640393, PMID 21868463, PMID 22050948, PMID 22196471, PMID 22315326, PMID 22351854, PMID 22553182, PMID 22844863, PMID 22986713, PMID 23574475, PMID 2395535, PMID 23993823, PMID 24192289, PMID 24295657, PMID 24616304
P01HD093363 (1), R01NR017433 (1)