3 completed, 3 recruiting, 3 unknown, 1 not yet recruiting. 12 Phase 2, 5 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 12 | Completed 3, Recruiting 3, Unknown 3, Not yet recruiting 1, Terminated 1, Withdrawn 1 |
| Phase 1 | 5 | Completed 2, Recruiting 1, Unknown 1, Withdrawn 1 |
Follow Tracheal Diseases: new trials by email Literature Review of Tracheal Diseases trials Research Report on Tracheal Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Combination Bevacizumab and PRGN-2012 in Adults With Recurrent Respiratory Papillomatosis (RRP) PRGN-2012, Bevacizumab - Respiratory Recurrent Papillomatosis (RRP), Human Papillomavirus (HPV) | Phase 2 | Not yet recruiting | National Cancer Institute (NCI) | 50 | 2026-11-15 | 2026-11-10 |
| Spray Cryotherapy for the Management of Benign Central Airway Stenosis (Cryo-BAS) Spray cryo therapy, Standard of Care (SOC) - Stenosis of Trachea | Phase 2 | Recruiting | Beth Israel Deaconess Medical Center | 50 | 2025-06-02 | 2026-11-10 |
| Nivolumab Combined With Chemotherapy in the Treatment of Primary Tracheal Squamous Cell Carcinoma Nivolumab Injection [Opdivo] - Neoplasms, Carcinoma, Squamous | Phase 2 | Recruiting | The First Affiliated Hospital of Guangzhou Medical University | 25 | 2023-08-15 | 2026-11-09 |
| Patient-Customized Bioprinting Technology for Practical Regeneration of the Respiratory Tract (Trachea) Three-dimensional patient-specific bioprinting trachea implantation - Thyroid Cancer | Phase 1 / Phase 2 | Unknown | Ja Seong Bae, MD, phD | 1 | 2023-07-17 | 2023-09-25 |
| Treatment of Laryngotracheal Stenosis Using Mesenchymal Stem Cells Olfactory mucosa-derived mesenchymal stem cells, Patients treated according to current clinical protocols - Tracheal Stenosis, Laryngeal Stenosis | Phase 2 | Unknown | Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus | 20 | 2021-06-01 | 2022-09-10 |
| VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma VMD-928 100 mg Tablet, VMD-928 Tablet and Pembrolizumab (200 mg) - Head and Neck Carcinoma, Adenoid Cystic Carcinoma | Phase 1 / Phase 2 | Recruiting | VM Oncology, LLC | 242 | 2018-06-08 | 2026-11-04 |
| Clinical Trial of Stem Cell Based Tissue Engineered Laryngeal Implants Stem cell based tissue engineered partial laryngeal implants - Disorder of Upper Respiratory System, Laryngostenosis | Phase 1 / Phase 2 | Withdrawn | University College, London | 2018-04-01 | 2018-06-06 | |
| Treatment of Laryngotracheal Stenosis Using Mesenchymal Stem Cells Olfactory mucosa-derived mesenchymal stem cells - Tracheal Stenosis, Laryngeal Stenosis | Phase 1 / Phase 2 | Completed | The Republican Research and Practical Center for Epidemiology and Microbiology | 12 | 2017-01-03 | 2019-06-07 |
| A Trail of a Novel Tracheal Radioactive Stent for the Malignant Airway Obstruction Traditional airway stent, Iodine-125 seeds - Malignant Airway Obstruction | Phase 2 | Unknown | Zhongda Hospital | 60 | 2015-05-01 | 2015-10-01 |
| Airway and/or Pulmonary Vessels Transplantation Airway and/or pulmonary Vessels Transplantation - Lung Cancer, Tracheal Neoplasm | Phase 1 / Phase 2 | Completed | Assistance Publique - Hôpitaux de Paris | 16 | 2011-05-31 | 2020-09-09 |
| Fetal Tracheal Balloon Study in Diaphragmatic Hernia Fetal tracheal obstruction with detachable balloon (device) - Diaphragmatic Hernia, Lung Disease | Phase 2 | Terminated | Rhode Island Hospital | 3 | 2008-09-01 | 2017-05-30 |
| Coated Endotracheal Tube and Mucus Shaver to Prevent Hospital-Acquired Infections Prolonged Mechanical Ventilation - Infection | Phase 2 | Completed | National Heart, Lung, and Blood Institute (NHLBI) | 24 | 2006-01-27 | 2017-07-02 |
Tracheal Stenosis (5) · Laryngostenosis (3) · Laryngeal Diseases (2) · Lung Neoplasms (2) · Tracheal Neoplasms (2) · Bacterial Infections (1) · Bronchial Diseases (1) · Carcinoma, Adenoid Cystic (1) · Carcinoma, Non-Small-Cell Lung (1) · Carcinoma, Squamous Cell (1) · Cross Infection (1) · Esophageal Neoplasms (1) · Head and Neck Neoplasms (1) · Hernia, Diaphragmatic (1)
Respiratory Tract Diseases (12) · Neoplasms by Site (5) · Otorhinolaryngologic Diseases (5) · Neoplasms (4) · Pathologic Processes (4) · Pathological Conditions, Signs and Symptoms (4) · Thoracic Neoplasms (4) · Congenital Abnormalities (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Head and Neck Neoplasms (3) · Laryngeal Diseases (3) · Lung Diseases (3) · Respiratory System Abnormalities (3) · Respiratory Tract Neoplasms (3)
Bevacizumab (1) · Carboplatin (1) · Combined Modality Therapy (1) · Nivolumab (1) · Paclitaxel (1) · Standard of Care (1) · Tablets (1) · pembrolizumab (1)
Assistance Publique - Hôpitaux de Paris (1) · Beth Israel Deaconess Medical Center (1) · Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus (1) · Ja Seong Bae, MD, phD (1) · National Cancer Institute (NCI) (1) · National Heart, Lung, and Blood Institute (NHLBI) (1) · Rhode Island Hospital (1) · The First Affiliated Hospital of Guangzhou Medical University (1) · The Republican Research and Practical Center for Epidemiology and Microbiology (1) · University College, London (1) · VM Oncology, LLC (1) · Zhongda Hospital (1)
United States (4) · Belarus (2) · China (2) · France (1) · Italy (1) · Puerto Rico (1) · South Korea (1) · United Kingdom (1)
Andrei Hancharou, Dr (1) · Andrei Y Hancharou, Dr (1) · Elvira Strinkevich, Dr (1) · Francois I Luks, MD, PhD (1) · Gao-jun Teng, Ph.D,MD (1) · Martin Birchall, Prof (1) · Scott M Norberg, D.O. (1) · Shuben Li, PhD (1) · Sung Won Kim, MD, PhD (1) · Valery Chekan, Dr (1) · Valery L Chekan, Dr (1)
PMID 26041482, PMID 26163763, PMID 26559535, PMID 29800033, PMID 30261427