4 completed, 2 enrolling by invitation, 1 not yet recruiting, 1 suspended. 4 Not applicable, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Completed 2, Enrolling by invitation 2 |
| Phase 1 | 1 | Suspended 1 |
| Phase 3 | 1 | Not yet recruiting 1 |
Follow Tracheomalacia: new trials by email Literature Review of Tracheomalacia trials Research Report on Tracheomalacia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Feasibility of Tracheobronchial Reconstruction Using Allogenic Aortic Patch in Children Cryopreserved aorta - Trachea Diseases, Tracheal Stenosis | Not applicable | Enrolling by invitation | National Taiwan University Hospital | 5 | 2026-12-01 | 2026-08-17 |
| Primary Posterior Tracheopexy Prevents Tracheal Collapse Randomisation between the PPT- and no-PPT-group, Primary Posterior Tracheopexy, Preoperative tracheobronchoscopy - Oesophageal Atresia With Tracheo-Oesophageal Fistula, Tracheomalacia | Not applicable | Enrolling by invitation | UMC Utrecht | 78 | 2024-09-01 | 2025-03-30 |
| Enhancing Lung Health in Kids With Structural Lung Damage and Malformations: Azithromycin (AZI) for Airway Infection Prevention Azithromycin 40 MG/ML, Placebo - Tracheomalacia, Bronchopulmonary Dysplasia (BPD) | Phase 3 | Not yet recruiting | Copenhagen University Hospital, Rigshospitalet | 150 | 2024-09-01 | 2024-05-14 |
| Dynamic Airway CT is Diagnostic for Tracheomalacia in Children Dynamic Airway CT scan (DA-CT) - Tracheomalacia | Not applicable | Completed | NYU Langone Health | 14 | 2023-08-10 | 2026-10-20 |
| Airway Pressure and Lumen Changes During NIV With Flexible Bronchoscopy NIV rate: 0/min, NIV rate: 10-20/min, NIV rate: 5-10/min - Airway Disease | Not applicable | Completed | Taipei Veterans General Hospital, Taiwan | 30 | 2018-01-01 | 2018-09-11 |
| A Study to Assess the Safety, Tolerability and Potential Efficacy of a Tracheal Replacement Consisting of a Tissue-engineered Tracheal Scaffold With Seeded Mesenchymal Cells Cadaveric decellularised tracheal scaffold seeded with autologous mesenchymal cells - Tracheomalacia, Tracheal Stenosis | Phase 1 | Suspended | Cell Therapy Catapult | 4 | 2016-09-01 | 2018-03-29 |
| Tracheobronchomalacia: Treatment Outcomes Tracheomalacia, Tracheobronchomalacia | Completed | Beth Israel Deaconess Medical Center | 150 | 2002-01-01 | 2017-02-03 | |
| Tracheal Mechanics During Bronchoscopy Tracheomalacia, Tracheobronchomalacia | Completed | Beth Israel Deaconess Medical Center | 145 | 1999-03-01 | 2017-03-10 |
Pulmonary Disease, Chronic Obstructive (2) · Tracheal Diseases (2) · Tracheal Stenosis (2) · Tracheobronchomalacia (2) · Bronchiectasis (1) · Bronchomalacia (1) · Bronchopulmonary Dysplasia (1) · Constriction, Pathologic (1) · Cystic Disease Of Lung (1) · Esophageal Atresia (1) · Esophageal atresia with or without tracheoesophageal fistula (1) · Tracheitis (1) · Tuberculosis (1) · Vascular Ring (1)
Cartilage Diseases (8) · Congenital Abnormalities (8) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (8) · Connective Tissue Diseases (8) · Musculoskeletal Abnormalities (8) · Musculoskeletal Diseases (8) · Respiratory Tract Diseases (8) · Skin and Connective Tissue Diseases (8) · Tracheal Diseases (6) · Tracheobronchomalacia (6) · Bronchial Diseases (4) · Lung Diseases (3) · Pathological Conditions, Signs and Symptoms (3) · Chronic Disease (2) · Disease Attributes (2)
Azithromycin (1)
Beth Israel Deaconess Medical Center (2) · Cell Therapy Catapult (1) · Copenhagen University Hospital, Rigshospitalet (1) · NYU Langone Health (1) · National Taiwan University Hospital (1) · Taipei Veterans General Hospital, Taiwan (1) · UMC Utrecht (1)
United States (3) · Taiwan (2) · United Kingdom (2) · Netherlands (1)
Armin Ernst, M.D. FCCP (1) · Colin Butler, MD, PhD (1) · Eleanor Muise, MD (1) · Jan F Svensson, MD, PhD (1) · John Vlot, MD, PhD (1) · Martin Birchall, MD, PhD (1) · Stephen H Loring, M.D. (1) · Wen-Jue Soong (1)
PMID 11037646, PMID 11210089, PMID 12041622, PMID 12365653, PMID 14521526, PMID 15236902, PMID 1653092, PMID 16903645, PMID 17389159, PMID 17426218, PMID 17475599, PMID 17699133, PMID 17908656, PMID 18364264, PMID 1848465, PMID 18842912, PMID 20934755, PMID 21493699, PMID 21513991, PMID 21626712, PMID 21640393, PMID 21868463, PMID 22196471, PMID 22553182, PMID 24616304, PMID 25316892, PMID 26188901, PMID 28576517, PMID 28817604, PMID 29420596, PMID 29861210, PMID 39672574, PMID 8309740, PMID 8605649, PMID 8854348