10 completed, 4 recruiting, 3 unknown, 2 terminated. 19 Phase 2, 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 19 | Completed 10, Recruiting 4, Unknown 3, Terminated 2 |
| Phase 1 | 3 | Completed 2, Unknown 1 |
Follow Torticollis: new trials by email Literature Review of Torticollis trials Research Report on Torticollis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Zinc as an Adjunctive Therapy for Cervical Dystonia Zinc citrate, Placebo - Cervical Dystonia | Phase 2 | Recruiting | University of Florida | 25 | 2026-06-01 | 2026-05-15 |
| A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia VIM0423, VIM0423 Placebo - Dystonia | Phase 2 | Recruiting | Vima Therapeutics | 100 | 2026-02-05 | 2026-10-26 |
| A Study of IPN10200 for the Treatment of Cervical Dystonia in Adults Corabotase, Placebo - Cervical Dystonia | Phase 2 | Recruiting | Ipsen | 132 | 2025-06-30 | 2026-09-08 |
| Study of the Oral Treatment MTR-601 in Cervical Dystonia MTR-601, Placebo - Cervical Dystonia | Phase 2 | Terminated | Motric Bio | 38 | 2025-02-28 | 2026-09-17 |
| Safety and Effectiveness of Valbenazine as Adjunct Therapy to Botulinum Toxin Injections in Cervical Dystonia Valbenazine, Placebo - Cervical Dystonia | Phase 2 | Recruiting | Virginia Commonwealth University | 20 | 2024-12-17 | 2026-06-04 |
| Extension Study of ABP-19000 to Evaluate Safety and Efficacy of Repeat Treatments of ABP-450 in Cervical Dystonia ABP-450 - Cervical Dystonia | Phase 2 | Completed | AEON Biopharma, Inc. | 51 | 2021-07-27 | 2024-08-22 |
| A Phase 2 Study to Evaluate the Safety and Efficacy of ABP-450 in the Treatment of Cervical Dystonia ABP-450, Placebo - Cervical Dystonia | Phase 2 | Completed | AEON Biopharma, Inc. | 61 | 2021-03-29 | 2024-02-14 |
| Safety and Tolerability of Perampanel in Cervical Dystonia Perampanel - Cervical Dystonia | Phase 1 / Phase 2 | Completed | University Health Network, Toronto | 25 | 2017-09-01 | 2020-04-07 |
| ASIS for Botox in Cervical Dystonia Gadolinium, Efficacy of Botox intramuscularly at Week 6, Efficacy of Botox intramuscularly at Week 12 - Cervical Dystonia Adults ,, Abnormal Head Position and Neck Pain for These 7 Muscle Groups: Splenius,Scalene,Sterno-cleido-mastoid,Levator Scapulae,Semispinalis,Trapezius,and Longissimus. | Phase 1 / Phase 2 | Unknown | li nguyen | 60 | 2016-01-01 | 2015-06-24 |
| Dose-escalating Safety and Preliminary Efficacy of DaxibotulinumtoxinA for Injection in Cervical Dystonia DaxibotulinumtoxinA - Torticollis (Spasmodic) | Phase 2 | Completed | Revance Therapeutics, Inc. | 37 | 2015-09-01 | 2019-11-06 |
| Study for Determine the Safety and Efficacy of Clostridium Botulinum Toxin Type A in Subjects With Cervical Dystonia MT10109, BOTOX(Registered trade mark) - Cervical Dystonia | Phase 2 | Completed | Medy-Tox | 60 | 2012-08-01 | 2014-09-08 |
| Clinical and Kinematic Assessment for Determination of Botox® Injection Parameters in Cervical Dystonia Botulinum Toxin Type A - Cervical Dystonia | Phase 2 | Unknown | Western University, Canada | 39 | 2012-01-01 | 2020-06-22 |
| Study to Evaluate Safety, Efficacy of Botulinum Toxin Type A in Patients With Cervical Dystonia botulinum toxin type A, botulinum toxin type A Formulation 2, Normal Saline - Cervical Dystonia | Phase 2 | Completed | Allergan | 242 | 2007-12-01 | 2016-01-05 |
| Efficacy of Dronabinol for the Treatment of Cervical Dystonia Dronabinol - Cervical Dystonia | Phase 2 | Unknown | University Health Network, Toronto | 38 | 2006-09-01 | 2008-09-09 |
| An Electrophysiological Study Of E2014 In Healthy Adult Male Japanese And Caucasian Subjects E2014 (Botulinum toxin type B), E2014 (Botulinum toxin type B) Placebo - Spasmodic Torticollis | Phase 2 | Completed | Eisai Limited | 48 | 2006-01-01 | 2013-04-25 |
| Keppra for Cervical Dystonia Keppra - Cervical Dystonia | Phase 2 | Terminated | University of South Florida | 17 | 2005-11-01 | 2018-11-23 |
| Randomized, Double-Blind, Placebo-Controlled, Parallel, Group Dose-Response, Study of E2014 in Patients WIth Spasmodic Torticollis BOTULINUM TOXIN TYPE B - Cervical Dystonia, Spasmodic Torticollis | Phase 2 | Completed | Eisai Co., Ltd. | 133 | 2004-06-01 | 2014-03-10 |
| Botulinum Toxin Type A (Botox) for the Treatment of Cervical Dystonia and Upper Thoracic Muscular Pain Botulinum Toxin Type A - Refractory Cervicothoracic Myofascial Pain Syndrome (CMPS), Cervical Dystonia | Phase 1 / Phase 2 | Completed | Vanderbilt University | 20 | 2004-03-01 | 2016-06-01 |
| Amlodipine Plus Botulinum Toxin for Focal Dystonia Amlodipine plus Botulinum toxin - Focal Dystonia | Phase 2 | Completed | National Institute of Neurological Disorders and Stroke (NINDS) | 16 | 2001-04-01 | 2013-04-01 |
Dystonia (2) · Dystonic Disorders (2)
Dyskinesias (19) · Neurologic Manifestations (19) · Pathological Conditions, Signs and Symptoms (19) · Signs and Symptoms (19) · Dystonia (17) · Nervous System Diseases (3) · Central Nervous System Diseases (2) · Movement Disorders (2)
Botulinum Toxins, Type A (5) · prabotulinumtoxin A (2) · rimabotulinumtoxinB (2) · Amlodipine (1) · Botulinum Toxins (1) · Dronabinol (1) · Gadolinium (1) · Gadolinium DTPA (1) · Levetiracetam (1) · Saline Solution (1) · Sodium Chloride (1) · perampanel (1) · valbenazine (1)
AEON Biopharma, Inc. (2) · University Health Network, Toronto (2) · Allergan (1) · Eisai Co., Ltd. (1) · Eisai Limited (1) · Ipsen (1) · Medy-Tox (1) · Motric Bio (1) · National Institute of Neurological Disorders and Stroke (NINDS) (1) · Revance Therapeutics, Inc. (1) · University of Florida (1) · University of South Florida (1) · Vanderbilt University (1) · Vima Therapeutics (1) · Virginia Commonwealth University (1)
United States (13) · Canada (5) · Czechia (2) · Germany (2) · Japan (2) · Poland (2) · United Kingdom (2) · Australia (1) · France (1) · Hungary (1) · India (1) · Italy (1) · Philippines (1) · Russia (1) · Serbia (1)
Joseph Jankovic (2) · Brian Berman (1) · Cynthia Comella (1) · Cynthia Comella, MD (1) · Hiroki Shimizu (1) · Lauren Fanty, MD (1) · Mandar Jog, MD (1) · Nubia Kaba (1) · Susan H Fox, MD PhD (1) · Susan H Fox, MRCP(UK), PhD (1) · Thomas L Davis, MD (1)