11 completed, 2 terminated, 1 recruiting, 1 unknown. 6 Phase 2, 3 Early Phase 1, 2 Not applicable, 2 Phase 4, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 4, Terminated 2 |
| Early Phase 1 | 3 | Completed 2, Unknown 1 |
| Not applicable | 2 | Completed 2 |
| Phase 4 | 2 | Completed 1, Recruiting 1 |
| Phase 1 | 1 | Completed 1 |
Follow prabotulinumtoxin A: new trials by email Literature Review of prabotulinumtoxin A trials Research Report on prabotulinumtoxin A
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparison of Dry Needling and Two Botulinum Toxins for Bruxism Dry Needling (DN), PrabotulinumtoxinA, Abobotulinumtoxina - Bruxism, Sleep Bruxism, Adult | Not applicable | Completed | Recep Tayyip Erdogan University | 72 | 2026-01-09 | 2026-05-20 |
| BoTox Into the Sternocleidomastoid Muscles (SCM) prabotulinumtoxinA-xvfs - Neck Muscle Issue | Phase 4 | Recruiting | Boston Medical Center | 30 | 2025-05-14 | 2026-08-31 |
| Effects of Microtox on Facial Skin Quality, Fine Wrinkles, and Texture PrabotulinumtoxinA-Xvfs, IncobotulinumtoxinA, saline solution (placebo) - Skin Aging, Skin Wrinkling | Phase 1 | Completed | Kalpna Kay Durairaj, MD, FACS | 20 | 2024-09-03 | 2025-10-21 |
| Spread of PrabotulinumtoxinA-xvfs Versus OnabotulinumtoxinA in the Treatment of Forehead Rhytides PrabotulinumtoxinA-Xvfs, OnabotulinumtoxinA - Rhytides | Early Phase 1 | Completed | Lupo Center for Aesthetic and General Dermatology | 10 | 2023-05-01 | 2024-03-13 |
| Non Interventional Safety Study of NUCEIVA for the Treatment of Moderate-to-Severe Glabellar Lines prabotulinumtoxinA - Glabellar Frown Lines | Completed | Evolus, Inc. | 756 | 2023-03-15 | 2026-06-30 | |
| Endoscopic Botulinum Toxin Injection in the Prevention of Postoperative Pancreatic Fistula Following Distal Pancreatectomy Botulinum Toxin Type A - Pancreatic Carcinoma | Phase 2 | Terminated | OHSU Knight Cancer Institute | 4 | 2023-03-01 | 2025-05-13 |
| Study to Demonstrate Safety and Duration of Effect of 40 Units of PrabotulinumtoxinA-xvfs to Treat Glabellar Lines PrabotulinumtoxinA-Xvfs, OnabotulinumtoxinA - Glabellar Frown Lines | Phase 2 | Completed | Evolus, Inc. | 154 | 2022-03-30 | 2024-09-04 |
| Evaluation of Four Injectable Neuromodulators in the Glabella Area Glabella Area Onabotulinumtoxina for Injection, Abobotulinumtoxina for Injection, IncobotulinumtoxinA for Injection - Cosmetic Techniques | Not applicable | Completed | University of Pennsylvania | 143 | 2022-03-04 | 2025-01-17 |
| Jeuveau Treatment of Glabellar Lines Using OLD Versus COLD prabotulinumtoxinA - Glabellar Frown Lines | Early Phase 1 | Completed | Clinical Testing of Beverly Hills | 30 | 2021-12-16 | 2024-02-06 |
| Extension Study of ABP-20001 to Evaluate Safety and Efficacy of Repeat Treatments of ABP-450 for Migraine Prevention ABP-450 - Migraine | Phase 2 | Terminated | AEON Biopharma, Inc. | 466 | 2021-10-19 | 2024-09-20 |
| Extension Study of ABP-19000 to Evaluate Safety and Efficacy of Repeat Treatments of ABP-450 in Cervical Dystonia ABP-450 - Cervical Dystonia | Phase 2 | Completed | AEON Biopharma, Inc. | 51 | 2021-07-27 | 2024-08-22 |
| A Phase 2 Study to Evaluate the Safety and Efficacy of ABP-450 in the Treatment of Cervical Dystonia ABP-450, Placebo - Cervical Dystonia | Phase 2 | Completed | AEON Biopharma, Inc. | 61 | 2021-03-29 | 2024-02-14 |
| Investigation of Safety and Efficacy of ABP-450 for Migraine Prevention in Adults ABP-450, Placebo - Migraine | Phase 2 | Completed | AEON Biopharma, Inc. | 797 | 2021-03-01 | 2024-09-04 |
| Split-Face Study Comparing Botox and Jeuveau in Treating Glabellar Lines PrabotulinumtoxinA, Onabotulinum toxin A - Glabellar Frown Lines | Early Phase 1 | Unknown | University of Southern California | 20 | 2021-01-01 | 2023-12-14 |
| Efficacy of Prabotulinum and Onabotulinum Toxin-A for Facial Wrinkles Onabotulinum toxin A, Prabotulinumtoxin A - Face, Skin Fold | Phase 4 | Completed | Instituto de Oftalmología Fundación Conde de Valenciana | 26 | 2020-06-15 | 2023-05-03 |
Migraine Disorders (2) · Torticollis (2) · Bruxism (1) · Facies (1) · Masticatory Muscles, Hypertrophy of (1) · Pancreatic Neoplasms (1) · Sleep Bruxism (1) · Temporomandibular Joint Disorders (1)
AEON Biopharma, Inc. (4) · Evolus, Inc. (2) · Boston Medical Center (1) · Clinical Testing of Beverly Hills (1) · Instituto de Oftalmología Fundación Conde de Valenciana (1) · Kalpna Kay Durairaj, MD, FACS (1) · Lupo Center for Aesthetic and General Dermatology (1) · OHSU Knight Cancer Institute (1) · Recep Tayyip Erdogan University (1) · University of Pennsylvania (1) · University of Southern California (1)
United States (12) · Australia (2) · Canada (2) · Germany (1) · Mexico (1) · Turkey (Türkiye) (1)
Joseph Jankovic (2) · Richard B Lipton, MD (2) · Stewart J Tepper, MD (2) · Brett C Sheppard, M.D., FACS (1) · Cynthia Comella (1) · Cynthia Comella, MD (1) · Jeffrey Spiegel, MD (1) · John Joseph, MD (1) · Kalpna K Durairaj, MD (1) · Rui Avelar (1) · Rui Avelar, MD (1) · Yonathan Garfias, PhD (1)