92 completed, 20 unknown, 13 recruiting, 12 terminated. 49 Phase 2, 37 Not applicable, 29 Phase 1, 11 Phase 3, 5 Phase 4.
Follow Tongue Diseases: new trials by email Literature Review of Tongue Diseases trials Research Report on Tongue Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ficerafusp Alfa, Pembrolizumab, and Stereotactic Body Radiotherapy (SBRT) for Head and Neck Squamous Cell Carcinoma (HNSCC) Hypofractionated Stereotactic Body Radiotherapy (SBRT), Pembrolizumab, Ficerafusp alfa - Head and Neck Squamous Cell Carcinoma, HPV-Negative Squamous Cell Carcinoma | Phase 1 / Phase 2 | Not yet recruiting | Washington University School of Medicine | 45 | 2026-09-30 | 2026-08-13 |
| Association Between Lingual Retraction and Hemodynamic Changes in Patients Receiving Dental Treatment Under General Anesthesia Trigeminocardiac Reflex, Hemodynamic Changes | Completed | Kırıkkale University | 85 | 2025-10-13 | 2026-04-09 | |
| Surgeon-performed Ultrasound for Real-time Guidance In Oral Cancer Surgeries - A Multicenter Randomized Controlled Trial Ultrasound imaging, Standard Treatment - Tongue Cancer, Oral Cancer | Not applicable | Recruiting | Tobias Todsen | 150 | 2025-09-15 | 2026-05-13 |
| High-Resolution PET-CT Imaging for Surgical Margin Visualization Intra-op PET/CT Specimen Scanner - Cancer, Solid Malignant Tumors | Not applicable | Recruiting | Vanderbilt-Ingram Cancer Center | 50 | 2025-09-03 | 2026-05-08 |
| Normative Ranges of Lingual Strength and Endurance and the Impact of the IOPI Lingual Strength Trainer on Quantitative Functional Outcomes and Patient-Reported Outcomes After Partial Glossectomy or Hemiglossectomy for Oral Tongue Cancer, An Unblinded: Randomized Pilot Study Iowa Oral Performance Instrument (IOPI) - Tongue Cancer | Not applicable | Recruiting | Memorial Sloan Kettering Cancer Center | 60 | 2025-08-07 | 2026-06-30 |
| Effect of Saccharomyces Boulardii CNCM I-745 on Gut Microbiota in Patients Undergoing Antibiotic Therapy (in the Context of Erythema Migrans (Early Skin Form of Lyme Borreliosis)) Amoxicillin + Saccharomyces boulardii CNCM I-745, Amoxicillin + Placebo, Stool samples - Erythema Migrans of Lyme Disease | Phase 4 | Recruiting | Biocodex | 120 | 2025-07-16 | 2025-08-27 |
| Anti-phospolipid Antibodies in Lyme Borreliosis Anti-phospholipid antibodies - Patients With Different Manifestations of Lyme Borreliosis, Persons With Nonspecific Symptoms and Positive Borrelia Antibodies in Serum | Not yet recruiting | University Medical Centre Ljubljana | 240 | 2025-05-15 | 2025-04-16 | |
| Window Trial of Fluorescently Labeled Panitumumab (Panitumumab-IRDye800) in Head and Neck Cancer Panitumumab IRDye 800 - HNSCC, HNSCC,Larynx, Pharynx and Oral Cavity | Phase 1 | Recruiting | Vanderbilt-Ingram Cancer Center | 70 | 2025-04-17 | 2026-08-03 |
| Submental Island Flap vs Radial Forearm Free Flap in Tongue Reconstruction Submental Island Pedicled Flap (SIPF), Radial Forearm Free Flap (RFFF) - Tongue Carcinoma, Tongue Neoplasms | Completed | Al-Azhar University | 28 | 2024-09-01 | 2026-09-15 | |
| Assessment of the Effect of Tumor Thickness and Site on Level IV Cervical Lymph Nodes in Squamous Cell Carcinoma of the Tongue and Floor of the Mouth: A Case Series Study removal of primary tumor, neck dissection - Tongue Neoplasms | Not applicable | Unknown | Cairo University | 20 | 2024-04-01 | 2024-05-29 |
| Anterolateral Thigh Myofascial Fat Composite Flap for Reconstruction of Hemiglossectomy Defects in Obese Patients With Tongue Cancer The anterolateral femoral myofascial fat composite flap (ALT-MF) repairs tongue defects in patients with tongue cancer - Tongue Cancer | Active not recruiting | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 35 | 2023-05-15 | 2026-07-06 | |
| Arabic PRO Measures for Head and Neck Cancer Radiotherapy. Radiation - Head and Neck Cancer, Head and Neck Neoplasms | Recruiting | King Saud University | 125 | 2023-05-01 | 2024-10-29 | |
| Prevalence of Tongue Anomalies in Egyptian Children no intervention - Tongue; Anomaly | Completed | Cairo University | 250 | 2023-03-25 | 2023-10-17 | |
| Surgical Margin Assessment by 3D Ultrasound 3D ultrasound - Tongue Cancer, Squamous Cell Carcinoma | Not applicable | Unknown | Copenhagen University Hospital, Rigshospitalet | 7 | 2023-01-01 | 2023-02-23 |
| Use of ST250 to Reconstruct Lateral Tongue Defects Tongue Neoplasms | Completed | Cairo University | 10 | 2022-07-01 | 2025-05-23 | |
| Effectiveness of Zinc Supplementation in Management of Patients With Symptomatic Benign Migratory Glossitis Zinc Sulfate 110 MG (Zinc 25 MG) Oral Tablet - Benign Migratory Glossitis | Phase 4 | Completed | mariam hamouda | 48 | 2021-09-06 | 2023-08-01 |
| Alpha Radiation Emitters Device for the Treatment of Cutaneous, Mucosal and Superficial Soft Tissue Neoplasia (DaRT) Device: Radiation: Diffusing Alpha Radiation Emitters Therapy (DaRT) - Skin Cancer, Mucosal Neoplasm of Oral Cavity | Not applicable | Terminated | Alpha Tau Medical LTD. | 2 | 2021-07-08 | 2025-12-08 |
| Customized 3D Printed Oral Stents During Head and Neck Radiotherapy Best Practice, Medical Device Usage and Evaluation - Head and Neck Carcinoma, Malignant Parotid Gland Neoplasm | Phase 2 | Active not recruiting | M.D. Anderson Cancer Center | 88 | 2021-05-26 | 2026-10-06 |
| The Registry of Oncology Outcomes Associated With Testing and Treatment Biomarker Testing (L), Systemic Treatment (T), Patient Reported Outcomes (P) - Adenocarcinoma, Adenocystic Carcinoma | Completed | Taproot Health | 167 | 2021-05-05 | 2024-12-18 | |
| Clinical Study Evaluating the Proper Surgical Safety Margin for Early Stage Oral Tongue Cancers 1.5 cm surgical safety margin for cT1-2N0 oral tongue cancers, 1.0 cm surgical safety margin for cT1-2N0 oral tongue cancers - Tongue Cancer, Tongue Cancer TNM Staging Primary Tumor (T) T1 | Not applicable | Terminated | Samsung Medical Center | 125 | 2021-01-18 | 2025-05-18 |
Showing 20 of 156. Sign in to see all of them.
Tongue Neoplasms (121) · Squamous Cell Carcinoma of Head and Neck (76) · Head and Neck Neoplasms (47) · Salivary Gland Neoplasms (39) · Mouth Neoplasms (31) · Glossitis, Benign Migratory (25) · Oropharyngeal Neoplasms (16) · Laryngeal Neoplasms (15) · Lyme Disease (15) · Carcinoma, Squamous Cell (14) · Hypopharyngeal Neoplasms (14) · Carcinoma, Non-Small-Cell Lung (13) · Nasopharyngeal Neoplasms (12) · Esthesioneuroblastoma, Olfactory (11) · Colonic Neoplasms (10)
Mouth Diseases (156) · Stomatognathic Diseases (156) · Neoplasms by Site (121) · Neoplasms (114) · Mouth Neoplasms (90) · Neoplasms by Histologic Type (90) · Neoplasms, Glandular and Epithelial (89) · Carcinoma (85) · Head and Neck Neoplasms (74) · Carcinoma, Squamous Cell (66) · Salivary Gland Diseases (40) · Respiratory Tract Diseases (29) · Otorhinolaryngologic Diseases (26) · Glossitis (25)
Cetuximab (16) · Cisplatin (16) · Radiotherapy, Intensity-Modulated (11) · Docetaxel (7) · Doxycycline (7) · Radiotherapy (7) · Erlotinib Hydrochloride (5) · Fluorouracil (5) · Carboplatin (4) · Everolimus (4) · Ultrasonography (4) · 130-nm albumin-bound paclitaxel (3) · Albumin-Bound Paclitaxel (3) · Biopsy (3) · Chemotherapy, Adjuvant (3)
National Cancer Institute (NCI) (20) · University Medical Centre Ljubljana (13) · Alpha Tau Medical LTD. (5) · Fox Chase Cancer Center (5) · Ohio State University Comprehensive Cancer Center (5) · Cairo University (4) · Memorial Sloan Kettering Cancer Center (4) · Roswell Park Cancer Institute (4) · Alliance for Clinical Trials in Oncology (3) · Radiation Therapy Oncology Group (3) · Selcuk University (3) · University of Chicago (3) · CENTOGENE GmbH Rostock (2) · Centre Antoine Lacassagne (2) · European Organisation for Research and Treatment of Cancer - EORTC (2)
United States (79) · Slovenia (13) · France (10) · Canada (7) · China (7) · United Kingdom (6) · Egypt (5) · India (5) · Germany (4) · Israel (4) · Turkey (Türkiye) (4) · Italy (3) · Saudi Arabia (3) · Brazil (2) · Denmark (2)
Franc Strle, MD (3) · Adriana R Marques, M.D. (2) · Anurag Singh (2) · Barbara Burtness (2) · Franc Strle, MD PhD (2) · Franc Strle, MD, PhD (2) · Jill Gilbert (2) · Peter Bauer, Prof. (2) · Sung Kim (2) · Tanguy Seiwert (2) · Ahmed Elkhadem, PhD (1) · Alexander Langerman (1) · Amit Agrawal (1) · Amit Agrawal, MD (1)
PMID 25057165, PMID 30075748, PMID 32223688, PMID 14520092, PMID 16380783, PMID 16792723, PMID 17985341, PMID 19138635, PMID 19372041, PMID 19602035, PMID 19735988, PMID 19907039, PMID 20187599, PMID 21367608, PMID 21917515, PMID 22252927, PMID 22523260, PMID 23188068, PMID 23639862, PMID 24182765, PMID 24733799, PMID 25684313, PMID 25965900, PMID 26062933, PMID 26611425, PMID 26928328, PMID 28029303, PMID 29149611, PMID 29346519, PMID 29385444, PMID 29505880, PMID 30768363, PMID 30850872, PMID 31405750, PMID 31611612, PMID 31618129, PMID 32633658, PMID 33507809, PMID 35945244, PMID 36537851, PMID 37650478, PMID 38240918, PMID 39454756, PMID 39841939, PMID 39868569, PMID 40166973, PMID 40925099, PMID 42185750, PMID 42289363
U10CA021115 (3), N01CM62201 (2), P30CA014599 (2), P30CA072720 (2), U01CA062502 (2), U10CA032102 (2), U10CA180868 (2), 2023 (1), N01CM00032 (1), N01CM00071 (1), N01CM00099 (1), N01CM00100 (1), N01CM62202 (1), N01CM62206 (1), P30CA006516 (1)