36 completed, 4 terminated, 4 unknown, 2 withdrawn. 49 Phase 2, 13 Phase 1, 1 Phase 3.
Follow Tongue Diseases: new trials by email Literature Review of Tongue Diseases trials Research Report on Tongue Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ficerafusp Alfa, Pembrolizumab, and Stereotactic Body Radiotherapy (SBRT) for Head and Neck Squamous Cell Carcinoma (HNSCC) Hypofractionated Stereotactic Body Radiotherapy (SBRT), Pembrolizumab, Ficerafusp alfa - Head and Neck Squamous Cell Carcinoma, HPV-Negative Squamous Cell Carcinoma | Phase 1 / Phase 2 | Not yet recruiting | Washington University School of Medicine | 45 | 2026-11-30 | 2026-11-03 |
| Customized 3D Printed Oral Stents During Head and Neck Radiotherapy Best Practice, Medical Device Usage and Evaluation - Head and Neck Carcinoma, Malignant Parotid Gland Neoplasm | Phase 2 | Active not recruiting | M.D. Anderson Cancer Center | 88 | 2021-05-26 | 2026-10-06 |
| Evaluation of the Effectiveness of the Selected Method of Treatment of Primary Burning Mouth Syndrome Clonazepam tablets, tongue pads - Burning Mouth Syndrome, Glossodynia | Phase 2 | Completed | Wroclaw Medical University | 58 | 2019-01-12 | 2021-07-22 |
| Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene A166 - HER2-positive Breast Cancer, HER2 Gene Mutation | Phase 1 / Phase 2 | Completed | Klus Pharma Inc. | 49 | 2018-07-16 | 2023-08-03 |
| S1702 Isatuximab in Treating Patients With Relapsed or Refractory Primary Amyloidosis Isatuximab, Laboratory Biomarker Analysis - Amorphous, Eosinophilic, and Acellular Deposit, Constipation | Phase 2 | Completed | SWOG Cancer Research Network | 43 | 2018-06-06 | 2025-09-09 |
| Correlation of FAZA PET Hypoxia Imaging To 3D Histology in Oral Tongue Cancer (18)F-Fluoroazomycin arabinoside, Pimonidazole - Tongue Cancer | Phase 1 / Phase 2 | Suspended | Sunnybrook Health Sciences Centre | 10 | 2018-01-25 | 2024-08-12 |
| High-activity Natural Killer Immunotherapy for Small Metastases of Tongue Cancer High-activity natural killer - Tongue Cancer | Phase 1 / Phase 2 | Completed | Fuda Cancer Hospital, Guangzhou | 20 | 2016-12-01 | 2019-09-12 |
| Combination of Cryosurgey and NK Immunotherapy for Recurrent Tongue Cancer Cryosurgery, NK immunotherapy - Recurrent Tongue Cancer | Phase 1 / Phase 2 | Completed | Fuda Cancer Hospital, Guangzhou | 30 | 2016-07-01 | 2019-09-12 |
| Role of Neo-adjuvant Chemotherapy in Tongue Preservation in Locally Advanced Squamous Cell Carcinoma of Oral Tongue Docetaxel, Cisplatin, 5FU - Tongue Neoplasms, Squamous Cell Carcinoma | Phase 2 | Unknown | HealthCare Global Enterprise Ltd. | 30 | 2016-04-01 | 2016-12-07 |
| Effect of COX-2 and EGFR Suppression on Molecular Markers of Angiogenesis and Proliferation in Squamous Cell Carcinoma of Oral Cavity - Prospective Randomized Study Arm1, Arm 2, Arm 3 - Oral Squamous Cell Carcinoma, Carcinoma of Buccal Mucosa | Phase 2 | Unknown | Tata Memorial Hospital | 64 | 2015-08-18 | 2022-04-28 |
| Reduced-Dose Intensity-Modulated Radiation Therapy With or Without Cisplatin in Treating Patients With Advanced Oropharyngeal Cancer Cisplatin, IMRT 6 weeks, IMRT 5 weeks - Stage III Oropharyngeal Squamous Cell Carcinoma, Stage IVA Oropharyngeal Squamous Cell Carcinoma | Phase 2 | Completed | NRG Oncology | 316 | 2014-10-01 | 2026-05-22 |
| Acetylcysteine Rinse in Reducing Saliva Thickness and Mucositis in Patients With Head and Neck Cancer Undergoing Radiation Therapy acetylcysteine, placebo, quality-of-life assessment - Mucositis, Oral Complications | Phase 2 | Completed | Mayo Clinic | 34 | 2014-04-01 | 2019-04-30 |
| Interstitial Photodynamic Therapy in Treating Patients With Recurrent Head and Neck Cancer Laboratory Biomarker Analysis, Photodynamic Therapy, Porfimer Sodium - Recurrent Laryngeal Squamous Cell Carcinoma, Recurrent Laryngeal Verrucous Carcinoma | Phase 2 | Terminated | Roswell Park Cancer Institute | 3 | 2014-04-01 | 2017-10-11 |
| Cisplatin With or Without WEE1 Inhibitor MK-1775 in Treating Patients With Recurrent or Metastatic Head and Neck Cancer Cisplatin, Laboratory Biomarker Analysis, Pharmacological Study - Recurrent Hypopharyngeal Squamous Cell Carcinoma, Recurrent Laryngeal Squamous Cell Carcinoma | Phase 2 | Terminated | National Cancer Institute (NCI) | 6 | 2014-03-01 | 2017-05-03 |
| Inulin and S. Salivarius Reduce Halitosis Inulin+SS, S salivarius, Placebo - Halitosis, Tongue Diseases | Phase 2 | Completed | Universidade de Passo Fundo | 45 | 2014-03-01 | 2020-08-19 |
| Radiation Therapy and Cisplatin With or Without Surgery in Treating Patients With Stage III-IV Oropharyngeal Cancer therapeutic conventional surgery, intensity-modulated radiation therapy, cisplatin - Stage III Squamous Cell Carcinoma of the Oropharynx, Stage IVA Squamous Cell Carcinoma of the Oropharynx | Phase 2 | Withdrawn | Radiation Therapy Oncology Group | 2013-12-01 | 2015-03-20 | |
| Botanical Therapy in Treating Mucositis in Patients With Head and Neck Cancer Who Have Undergone Chemoradiation Therapy placebo, quality-of-life assessment, questionnaire administration - Mucositis, Recurrent Squamous Cell Carcinoma of the Hypopharynx | Phase 2 | Withdrawn | Roswell Park Cancer Institute | 2013-05-01 | 2013-05-15 | |
| PI3K Inhibitor BKM120 and Cetuximab in Treating Patients With Recurrent or Metastatic Head and Neck Cancer PI3K inhibitor BKM120, cetuximab - Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma, Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Phase 1 / Phase 2 | Completed | University of Chicago | 12 | 2013-05-01 | 2021-10-05 |
| 18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapy 18F-fludeoxyglucose (18F-FDG), 18F-FPPRGD2 - Adult Giant Cell Glioblastoma, Adult Glioblastoma | Phase 1 / Phase 2 | Completed | Sanjiv Sam Gambhir | 25 | 2013-03-04 | 2019-10-03 |
| A Study of Tongue Conservation Surgery for Oral Tongue Cancer Induction chemotherapy, Tongue conservation surgery, postoperative CCRT - Tongue Cancer, Chemotherapy Effect | Phase 2 | Terminated | Taipei Veterans General Hospital, Taiwan | 23 | 2011-07-18 | 2017-05-30 |
Showing 20 of 49. Sign in to see all of them.
Tongue Neoplasms (46) · Squamous Cell Carcinoma of Head and Neck (31) · Salivary Gland Neoplasms (17) · Head and Neck Neoplasms (16) · Mouth Neoplasms (13) · Oropharyngeal Neoplasms (9) · Hypopharyngeal Neoplasms (8) · Laryngeal Neoplasms (8) · Nasopharyngeal Neoplasms (6) · Lymphoid Interstitial Pneumonia (5) · Carcinoma, Renal Cell (4) · Carcinoma, Squamous Cell (4) · Pancreatic Neoplasms (4) · Breast Neoplasms (3) · Carcinoma, Non-Small-Cell Lung (3)
Mouth Diseases (49) · Stomatognathic Diseases (49) · Neoplasms (46) · Neoplasms by Site (46) · Neoplasms by Histologic Type (37) · Carcinoma (36) · Neoplasms, Glandular and Epithelial (36) · Mouth Neoplasms (33) · Head and Neck Neoplasms (30) · Carcinoma, Squamous Cell (29) · Salivary Gland Diseases (18) · Otorhinolaryngologic Diseases (12) · Otorhinolaryngologic Neoplasms (12) · Pharyngeal Diseases (12)
Cisplatin (11) · Cetuximab (9) · Radiotherapy, Intensity-Modulated (6) · Docetaxel (4) · Radiotherapy (4) · Paclitaxel (3) · 130-nm albumin-bound paclitaxel (2) · Albumin-Bound Paclitaxel (2) · Carboplatin (2) · Celecoxib (2) · Erlotinib Hydrochloride (2) · Everolimus (2) · Fluorouracil (2) · Sirolimus (2) · Sorafenib (2)
National Cancer Institute (NCI) (14) · Fox Chase Cancer Center (2) · Fuda Cancer Hospital, Guangzhou (2) · GERCOR - Multidisciplinary Oncology Cooperative Group (2) · Radiation Therapy Oncology Group (2) · Roswell Park Cancer Institute (2) · University of Texas Southwestern Medical Center (2) · Centre Antoine Lacassagne (1) · Eastern Cooperative Oncology Group (1) · HealthCare Global Enterprise Ltd. (1) · Klus Pharma Inc. (1) · M.D. Anderson Cancer Center (1) · Mayo Clinic (1) · Memorial Sloan Kettering Cancer Center (1) · NRG Oncology (1)
United States (33) · Canada (5) · China (3) · France (3) · India (2) · Ireland (1) · Poland (1) · Saudi Arabia (1) · South Korea (1) · Switzerland (1) · United Kingdom (1)
Jill Gilbert (2) · Tanguy Seiwert (2) · Amit Agrawal (1) · Anna Lee (1) · Anurag Singh (1) · Barbara Burtness (1) · Chris Boshoff (1) · Christopher Thomas (1) · David G. Pfister, MD (1) · Emma Scott (1) · Eric Winquist (1) · Fernando Fornari (1) · Floyd C. Holsinger (1) · Frank Meyskens (1) · Gary G. Schwartz, MD, PhD, MPH (1)
PMID 25057165, PMID 14520092, PMID 22252927, PMID 23639862, PMID 25684313, PMID 25965900, PMID 26062933, PMID 26611425, PMID 28029303, PMID 29346519, PMID 30850872, PMID 31405750, PMID 33507809, PMID 40166973, PMID 40925099
U10CA021115 (2), N01CM00032 (1), N01CM00071 (1), N01CM00099 (1), N01CM00100 (1), N01CM62201 (1), N01CM62202 (1), N01CM62206 (1), P30CA006516 (1), P30CA006927 (1), P30CA014599 (1), P30CA015083 (1), P30CA016056 (1), P30CA016672 (1), P30CA022453 (1)