8 recruiting, 7 completed, 2 active not recruiting, 1 unknown. 18 Phase 3, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 18 | Recruiting 8, Completed 7, Active not recruiting 2, Unknown 1 |
| Phase 2 | 4 | Completed 2, Active not recruiting 1, Recruiting 1 |
Follow Thyroid Cancer: new trials by email Literature Review of Thyroid Cancer trials Research Report on Thyroid Cancer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of AL2846 Capsule Versus Placebo in the Treatment of Advanced Radioiodine-Refractory Differentiated Thyroid Carcinoma AL2846 Capsules, AL2846 Placebo - Thyroid Cancer | Phase 3 | Recruiting | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 144 | 2025-04-18 | 2025-12-31 |
| Trop2-targeted immunoPET Imaging of Solid Tumors [68Ga]Ga-NOTA-T4, [68Ga]Ga-NOTA-RT4, [18F]F-RESCA-T4 - Solid Tumor, Solid Carcinoma | Phase 2 / Phase 3 | Recruiting | RenJi Hospital | 400 | 2024-12-23 | 2026-05-29 |
| Selective Neck Dissection Versus Modified Neck Dissection in PTC Lymph node tracer navigated selective neck dissection, Modified neck dissection - Thyroid Cancer | Phase 3 | Recruiting | Fudan University | 250 | 2024-11-19 | 2026-02-27 |
| Adjuvant Radiotherapy in High Risk Locally Advanced DTC Radiotherapy, radioiodine treatment - Thyroid Cancer | Phase 3 | Recruiting | Fudan University | 124 | 2024-07-11 | 2026-02-27 |
| Artificial Tears to Prevent Nasolacrimal Duct Obstruction in Patients Treated With Radioactive Iodine for Thyroid Cancer Artificial Tears Methylcellulose - Nasolacrimal Duct Obstruction, Thyroid Cancer | Phase 3 | Recruiting | Vanderbilt University Medical Center | 100 | 2023-08-21 | 2026-11-03 |
| Evaluation of Metformin Effect on the Fertility of Women Treated With 131I for Thyroid Cancer metformin, Radioactive iodine (I-131) - Thyroid Cancer | Phase 3 | Recruiting | Medical University of Bialystok | 160 | 2022-11-01 | 2026-10-21 |
| A Prospective, Open-label, Multicenter, Randomized Controlled Phase III Study of Prophylactic Central Neck Dissection in Low-risk Papillary Thyroid Cancer prophylactic central neck dissection - Thyroid Cancer, Recurrence | Phase 3 | Recruiting | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 1199 | 2022-07-01 | 2023-10-13 |
| Systematic Radioiodine Administration Versus Decision of Radioiodine Treatment Guided by a Post-operative Work-up Systematic RAI-treatment, Decision of RAI-treatment guided by a post-operative assessment - Thyroid Cancer, Intermediate Risk | Phase 3 | Recruiting | Centre Francois Baclesse | 368 | 2020-03-02 | 2026-06-25 |
| ESTIMation of the ABiLity of Prophylactic Central Compartment Neck Dissection to Modify Outcomes in Low-risk Differentiated Thyroid Cancer total thyroidectomy with bilateral prophylactic central compartment (level VI) neck dissection, total thyroidectomy alone without neck dissection - Thyroid Cancer | Phase 3 | Active not recruiting | Gustave Roussy, Cancer Campus, Grand Paris | 352 | 2018-08-08 | 2026-03-06 |
| IoN- Is Ablative Radio-iodine Necessary for Low Risk Differentiated Thyroid Cancer Patients I131 1.1 GBq, No Radioactive iodine (No-RAI) ablation - Thyroid Cancer, Thyroid Neoplasms | Phase 2 / Phase 3 | Active not recruiting | University College, London | 504 | 2012-06-26 | 2026-05-07 |
| A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Trial of Lenvatinib (E7080) in 131I-Refractory Differentiated Thyroid Cancer (DTC) Lenvatinib, Placebo - Thyroid Cancer | Phase 3 | Completed | Eisai Inc. | 392 | 2011-03-17 | 2023-06-22 |
| Efficacy of Subfascial Approach in Thyroidectomy to Quality of Life in Thyroid Disease Patients subfascial flap, subplatysmal flap - Thyroid Cancer | Phase 2 / Phase 3 | Completed | Samsung Medical Center | 86 | 2010-03-01 | 2012-06-11 |
| Decision Making on Radioactive Iodine Treatment for Papillary Thyroid Cancer Decision aid exposure - Thyroid Cancer | Phase 2 / Phase 3 | Completed | University Health Network, Toronto | 74 | 2010-02-01 | 2016-11-29 |
| Prophylactic Central Lymph Node Dissection in Papillary Thyroid Microcarcinoma Prophylactic central lymph node dissection - Thyroid Cancer | Phase 3 | Completed | Samsung Medical Center | 258 | 2009-01-01 | 2016-04-15 |
| Efficacy of XL184 (Cabozantinib) in Advanced Medullary Thyroid Cancer XL184, Placebo - Thyroid Cancer | Phase 3 | Completed | Exelixis | 330 | 2008-06-01 | 2021-04-20 |
| Medico-Economic Comparison of Four Strategies of Radioiodine Ablation in Thyroid Carcinoma Patients Thyrogen, thyroid hormone withdrawal, iode 131 - Thyroid Cancer | Phase 3 | Unknown | Gustave Roussy, Cancer Campus, Grand Paris | 950 | 2007-02-01 | 2007-02-19 |
| An Efficacy Study Comparing ZD6474 to Placebo in Medullary Thyroid Cancer ZD6474 (Vandetanib) - Thyroid Cancer | Phase 3 | Completed | Genzyme, a Sanofi Company | 331 | 2006-11-23 | 2025-09-24 |
| The Usefulness of Staining Lymph Nodes During Operations for Cancer Thyroid in Detecting the Nodes That Have Cancer detecting lymph node metastasis by staining - Thyroid Cancer, Lymph Node Metastasis | Phase 3 | Completed | University of Alexandria | 45 | 2002-12-01 | 2009-07-15 |
Thyroid Neoplasms (18) · Carcinoma, Medullary (2) · Lymphatic Metastasis (2) · Thyroid Cancer, Papillary (2) · Adenocarcinoma, Follicular (1) · Carcinoma, Transitional Cell (1) · Cholangiocarcinoma (1) · Endometrial Neoplasms (1) · Familial medullary thyroid carcinoma (1) · Head and Neck Neoplasms (1) · Lacrimal Duct Obstruction (1) · Liver Neoplasms (1) · Lung Neoplasms (1) · Nasopharyngeal Neoplasms (1) · Ovarian Neoplasms (1)
Endocrine Gland Neoplasms (18) · Endocrine System Diseases (18) · Neoplasms (18) · Neoplasms by Site (18) · Thyroid Diseases (18) · Head and Neck Neoplasms (17) · Adenocarcinoma (5) · Carcinoma (5) · Neoplasms by Histologic Type (5) · Neoplasms, Glandular and Epithelial (5) · Pathologic Processes (3) · Pathological Conditions, Signs and Symptoms (3) · Adenocarcinoma, Papillary (2) · Carcinoma, Neuroendocrine (2) · Neoplasm Metastasis (2)
Iodine-131 (1) · Metformin (1) · Neck Dissection (1) · Radiotherapy (1) · Sodium Iodide (1) · Thyrotropin Alfa (1) · lenvatinib (1) · vandetanib (1)
Fudan University (2) · Gustave Roussy, Cancer Campus, Grand Paris (2) · Samsung Medical Center (2) · Cancer Institute and Hospital, Chinese Academy of Medical Sciences (1) · Centre Francois Baclesse (1) · Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (1) · Eisai Inc. (1) · Exelixis (1) · Genzyme, a Sanofi Company (1) · Medical University of Bialystok (1) · RenJi Hospital (1) · University College, London (1) · University Health Network, Toronto (1) · University of Alexandria (1) · Vanderbilt University Medical Center (1)
France (6) · China (5) · South Korea (5) · Canada (4) · Poland (4) · United States (4) · Austria (3) · Belgium (3) · Brazil (3) · Denmark (3) · Germany (3) · Italy (3) · Portugal (3) · Russia (3) · Spain (3)
Agnieszka Adamska, Assoc.Prof. (1) · Annie M Sawka, MD, PhD (1) · David P Goldstein, MD (1) · Han-Sin Jeong, MD, PhD (1) · Jianjun Liu, Ph.D. & M.D. (1) · Ujjal Mallick, MBBS MS FRCR (1) · Weijun Wei, Ph.D. & M.D. (1) · Yasser M Hamza, A Professor (1)
PMID 22025146, PMID 22551127, PMID 22753906, PMID 23009127, PMID 24002501, PMID 25671254, PMID 26088605, PMID 26195199, PMID 26426092, PMID 27548104, PMID 28237867, PMID 29045520, PMID 29807824, PMID 30471649, PMID 33611104, PMID 33637020, PMID 37118818, PMID 40543520, PMID 41469668
2005 (1), 2019 (1)