38 completed, 8 terminated, 7 active not recruiting, 6 unknown. 35 Phase 2, 12 Phase 1, 8 Not applicable, 4 Phase 3.
Follow Adenocarcinoma, Follicular: new trials by email Literature Review of Adenocarcinoma, Follicular trials Research Report on Adenocarcinoma, Follicular
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Personalized Cancer Support (Thrive Track) to Manage the Emotional Needs of Young Adults With Thyroid, Melanoma and Testicular Cancer, PerCS-YA Trial Internet-Based Intervention, Interview, Questionnaire Administration - Differentiated Thyroid Gland Carcinoma, Malignant Testicular Neoplasm | Not applicable | Not yet recruiting | University of Michigan Rogel Cancer Center | 142 | 2026-12-01 | 2026-10-15 |
| Bethesda Classification and Risk Stratification in Differentiated Thyroid Carcinoma Differentiated Thyroid Carcinoma, Papillary Thyroid Carcinoma | Not yet recruiting | Assiut University | 100 | 2026-10-26 | 2026-10-05 | |
| Health and Wellness Coaching to Improve Adherence to Healthy Habits and Treatment Plans in Papillary and Follicular Thyroid Cancer Survivors Counseling, Interview, Questionnaire Administration - Thyroid Gland Follicular Carcinoma, Thyroid Gland Papillary Carcinoma | Not applicable | Recruiting | Mayo Clinic | 20 | 2026-06-23 | 2026-07-08 |
| XL092 for the Treatment of Locally Advanced or Metastatic Radioiodine Refractory Differentiated Thyroid Cancer Biospecimen Collection, Computed Tomography, Magnetic Resonance Imaging - Locally Advanced Differentiated Thyroid Gland Carcinoma, Locally Advanced Poorly Differentiated Thyroid Gland Carcinoma | Phase 2 | Recruiting | Jochen Lorch | 33 | 2025-06-06 | 2026-06-26 |
| Incidental Thyroid Cancer in Cases With Inflammatory Thyroid Lesion total thyroidectomy - Papillary Thyroid Cancer, Hashimoto Disease | Not applicable | Completed | Minia University | 98 | 2025-02-01 | 2026-08-11 |
| Vemurafenib and Cobimetinib for the Treatment of Patients With High Risk Differentiated Thyroid Carcinoma With BRAFV600E Mutation Biospecimen Collection, Cobimetinib, Computed Tomography - Thyroid Gland Follicular Carcinoma, Thyroid Gland Oncocytic Carcinoma | Phase 2 | Recruiting | City of Hope Medical Center | 21 | 2024-07-15 | 2026-02-02 |
| Radioiodine Planar and a SPECT/CT Imaging With Iodine-123 for Evaluation of Follicular Thyroid Nodules Prior to Surgery Computed Tomography, Iodine I-123, Planar Imaging - Thyroid Gland Follicular Carcinoma | Terminated | Mayo Clinic | 2 | 2023-11-10 | 2026-08-11 | |
| Restor. I-131 Upt. + Selpercatinib in RET F-P RAI-R TC Selpercatinib, Sodium Iodine I-131, rhTSH - Thyroid Cancer, Thyroid Carcinoma | Phase 2 | Recruiting | Massachusetts General Hospital | 30 | 2023-03-01 | 2024-12-12 |
| Correlation Between Various Urinary Exosomal Protein Biomarkers and Pathological Manifestation in Thyroid Follicular Neoplasm: Early and Pre-operative Diagnosis of Follicular Thyroid Cancer Thyroid Cancer, Follicular Thyroid Cancer | Active not recruiting | National Taiwan University Hospital | 50 | 2022-08-01 | 2026-04-13 | |
| Evaluation of 177Lu-DOTA-EB-FAPI in Patients With Metastatic Radioactive Iodine Refractory Thyroid Cancer 177Lu-DOTA-EB-FAPI 1 radionuclide therapy, 177Lu-DOTA-EB-FAPI 2 radionuclide therapy, 177Lu-DOTA-EB-FAPI 3 radionuclide therapy - Refractory Thyroid Gland Carcinoma, Refractory Thyroid Gland Papillary Carcinoma | Phase 1 | Completed | The First Affiliated Hospital of Xiamen University | 12 | 2022-06-15 | 2025-04-01 |
| Evaluation of 18F-TFB PET/CT Scan in Patients With Differentiated Thyroid Cancer Computed Tomography, Fluorine F 18 Tetrafluoroborate, Positron Emission Tomography - Differentiated Thyroid Gland Carcinoma, Thyroid Gland Follicular Carcinoma | Terminated | Mayo Clinic | 11 | 2022-04-22 | 2026-09-24 | |
| Urinary Exosomal Biomarkers of Thyroglobulin and Galectin-3 for Prognosis and Follow-up in Patients of Thyroid Cancer Thyroid Cancer, Papillary Thyroid Cancer | Active not recruiting | National Taiwan University Hospital | 103 | 2021-08-19 | 2026-04-13 | |
| PDR001 Combination Therapy for Radioiodine-Refractory Thyroid Cancer Trametinib, Dabrafenib, PDR001 - Thyroid Cancer, Thyroid Cancer, Follicular | Phase 2 | Active not recruiting | Memorial Sloan Kettering Cancer Center | 19 | 2020-09-02 | 2026-09-17 |
| Testing the Combination of Cabozantinib, Nivolumab, and Ipilimumab (CaboNivoIpi) for Advanced Differentiated Thyroid Cancer Biospecimen Collection, Cabozantinib S-malate, Computed Tomography - Differentiated Thyroid Gland Carcinoma, Follicular Variant Thyroid Gland Papillary Carcinoma | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 11 | 2020-02-10 | 2026-07-31 |
| Durvalumab Plus Tremelimumab for the Treatment of Patients With Progressive, Refractory Advanced Thyroid Carcinoma -The DUTHY Trial Durvalumab, Tremelimumab - Metastatic Thyroid Papillary Carcinoma, Metastatic Thyroid Follicular Carcinoma | Phase 2 | Terminated | Grupo Espanol de Tumores Neuroendocrinos | 79 | 2019-04-02 | 2026-03-11 |
| Lenvatinib and Iodine Therapy in Treating Patients With Radioactive Iodine-Sensitive Differentiated Thyroid Cancer Lenvatinib - Differentiated Thyroid Gland Carcinoma, Thyroid Gland Follicular Carcinoma | Phase 2 | Terminated | Emory University | 4 | 2019-01-16 | 2022-11-10 |
| A Study of Cabozantinib Compared With Placebo in Subjects With Radioiodine-refractory Differentiated Thyroid Cancer Who Have Progressed After Prior Vascular Endothelial Growth Factor Receptor (VEGFR) -Targeted Therapy Cabozantinib, Placebo - Differentiated Thyroid Cancer | Phase 3 | Active not recruiting | Exelixis | 187 | 2018-10-05 | 2026-10-20 |
| Psychological Impact of a Sophrological Accompaniment During the Announcement of Thyroid Cancer sophrology sessions - Follicular Thyroid Cancer | Not applicable | Unknown | Assistance Publique Hopitaux De Marseille | 232 | 2018-09-01 | 2018-08-21 |
| Adaptive Tyrosine Kinase Inhibitor (TKI) Therapy In Patients With Thyroid Cancer Lenvatinib, Sorafenib, Cabozantinib - Thyroid Cancer, Thyroid Cancer, Medullary | Phase 2 | Terminated | H. Lee Moffitt Cancer Center and Research Institute | 6 | 2018-08-06 | 2021-07-14 |
| Effectiveness of Intraoperative Neuromonitoring of External Branch of Superior Laryngeal Nerve During Thyroid Surgery Using Neuromonitoring to find EBSLN - Carcinoma, Papillary, Follicular | Not applicable | Terminated | Seoul National University Hospital | 5 | 2018-04-06 | 2022-01-28 |
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Thyroid Cancer, Papillary (59) · Thyroid Neoplasms (48) · Carcinoma, Medullary (21) · Head and Neck Neoplasms (15) · Thyroid Carcinoma, Anaplastic (15) · Salivary Gland Neoplasms (10) · Squamous Cell Carcinoma of Head and Neck (9) · Thyroid cancer, Hurthle cell (9) · Esthesioneuroblastoma, Olfactory (7) · Carcinoma, Non-Small-Cell Lung (6) · Colonic Neoplasms (6) · Carcinoma, Renal Cell (5) · Parathyroid Neoplasms (5) · Adrenocortical Carcinoma (4)
Adenocarcinoma (67) · Carcinoma (67) · Neoplasms by Histologic Type (67) · Neoplasms, Glandular and Epithelial (67) · Neoplasms (65) · Endocrine Gland Neoplasms (62) · Endocrine System Diseases (62) · Neoplasms by Site (62) · Thyroid Diseases (61) · Adenocarcinoma, Papillary (60) · Head and Neck Neoplasms (47) · Neoplasms, Germ Cell and Embryonal (24) · Neoplasms, Nerve Tissue (24) · Neuroectodermal Tumors (24) · Neuroendocrine Tumors (23)
Magnetic Resonance Spectroscopy (9) · Iodine-131 (8) · Thyrotropin Alfa (5) · 2-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole (3) · Fluorodeoxyglucose F18 (3) · Specimen Handling (3) · Sunitinib (3) · X-Rays (3) · cabozantinib (3) · lenvatinib (3) · trametinib (3) · Everolimus (2) · Gefitinib (2) · Interviews as Topic (2) · Radiotherapy (2)
National Cancer Institute (NCI) (16) · Mayo Clinic (3) · Academic and Community Cancer Research United (2) · European Organisation for Research and Treatment of Cancer - EORTC (2) · Exelixis (2) · Massachusetts General Hospital (2) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (2) · National Taiwan University Hospital (2) · University College, London (2) · University of Washington (2) · Amgen (1) · Assistance Publique - Hôpitaux de Paris (1) · Assistance Publique Hopitaux De Marseille (1) · Assiut University (1) · Bhavana Konda (1)
United States (45) · Canada (4) · France (4) · Germany (4) · Italy (3) · Netherlands (3) · South Korea (3) · Taiwan (3) · United Kingdom (3) · Spain (2) · Argentina (1) · Australia (1) · Austria (1) · Belgium (1) · Brazil (1)
Manisha Shah (3) · Alan L Ho (2) · David Pfister (2) · Kenneth Ain, MD (2) · Steven Sherman (2) · Abd Moain Abu Dabrh, MB, BCh, MS (1) · Alan L Ho, MD, PhD (1) · Anthony W. Tolcher, MD (1) · Barry L. Gause, MD (1) · Bhavana Konda (1) · Bhavana Konda, MD (1) · Bryan R Haugen (1) · Byung Chul Cho (1) · Chih-Yi Liao (1)
PMID 16522694, PMID 17985341, PMID 17985985, PMID 18596272, PMID 18854394, PMID 19372041, PMID 19602035, PMID 19735988, PMID 19850694, PMID 20145168, PMID 20739388, PMID 21367608, PMID 22551128, PMID 23868427, PMID 24050953, PMID 24827131, PMID 26671977, PMID 27169792, PMID 28662033, PMID 28817373, PMID 29020892, PMID 29192093, PMID 29912343, PMID 30501974, PMID 31085763, PMID 32475305, PMID 33720068, PMID 34237250, PMID 34541894, PMID 35658604, PMID 36795619, PMID 37219859, PMID 38062732, PMID 39133806, PMID 40543520, PMID 41935063
N01CM62207 (4), N01CM62206 (3), P30CA015083 (3), N01CM00071 (2), N01CM00099 (2), N01CM62201 (2), N01CM62202 (2), P30CA008748 (2), P30CA014599 (2), P30CA016058 (2), U01CA076576 (2), 2005 (1), 2014 (1), 2018 (1), N01CM00032 (1)