3 terminated, 2 completed, 2 recruiting, 2 unknown. 10 Phase 2, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 10 | Terminated 3, Completed 2, Recruiting 2, Unknown 2, Not yet recruiting 1 |
| Phase 3 | 3 | Not yet recruiting 1, Terminated 1, Unknown 1 |
Follow Thoracic Diseases: new trials by email Literature Review of Thoracic Diseases trials Research Report on Thoracic Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pharmacologic Therapies to Mitigate Radiation- Associated Heart Disease Atorvastatin and Lisinopril, Placebo - Chest Wall Tumor, Breast Cancer | Phase 2 | Recruiting | UNC Lineberger Comprehensive Cancer Center | 60 | 2026-08-12 | 2026-09-17 |
| 6 vs 3 Cycles of Neoadjuvant Chemotherapy for Potentially Resectable Locally Advanced Thymic Epithelial Tumors Cyclophosphamide, Doxorubicin, and Cisplatin (CAP), nab-Paclitaxel and Carboplatin - Thymoma and Thymic Carcinoma | Phase 2 / Phase 3 | Not yet recruiting | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 116 | 2026-03-01 | 2026-03-11 |
| Comparative Analysis of the Lung Inflammatory Response After Thoracic Surgery With Single or Double Lung Ventilation: a Randomized, Pilot, Trial two lung ventilation, one lung ventilation - Thoracic Diseases, Surgery | Phase 2 | Completed | Universidade do Extremo Sul Catarinense - Unidade Academica de Ciecias da Saude | 40 | 2023-07-20 | 2024-05-08 |
| Phase II Trial of Lung Chemoemobolization Computed Tomography, Ethiodized Oil, Mitomycin - Lung Non-Small Cell Carcinoma, Mediastinal Neoplasm | Phase 2 | Recruiting | City of Hope Medical Center | 30 | 2023-05-12 | 2026-03-05 |
| MR-linac Guided Adaptive Radiotherapy for Inoperable Mediastinal Tumor Unity-based MR-Linac guided Radiotherapy - Mediastinal Tumor | Phase 2 | Unknown | Sun Yat-sen University | 59 | 2021-10-01 | 2021-12-20 |
| Liposomal Bupivacaine for Pain Control Following Thoracic Surgery. Liposomal bupivacaine, Bupivacaine, Epinephrine - Pain, Postoperative, Thoracic Diseases | Phase 2 / Phase 3 | Unknown | Massachusetts General Hospital | 200 | 2017-02-01 | 2017-01-30 |
| Pembrolizumab in Subjects With Incurable Platinum-Refractory Germ Cell Tumors Pembrolizumab - Germ Cell Neoplasms, Testicular Neoplasms | Phase 2 | Terminated | Nasser Hanna, M.D. | 12 | 2016-01-01 | 2022-07-11 |
| Belinostat (PXD101) to Treat Tumors of the Thymus at an Advanced Stage Belinostat (PDX101) - Thymoma, Thymic Carcinoma | Phase 2 | Completed | National Cancer Institute (NCI) | 41 | 2007-12-01 | 2015-09-30 |
| Efficacy, Immunogenicity, and Safety of a Single Dose of V710 in Adult Patients Scheduled for Cardiothoracic Surgery (V710-003 AM2) V710, Placebo - Staphylococcus Aureus, Bacteremia | Phase 2 / Phase 3 | Terminated | Merck Sharp & Dohme LLC | 8031 | 2007-12-01 | 2015-10-02 |
| Weekly Topotecan With Docetaxel in Recurrent Small Cell Lung Cancer Intravenous Topotecan, Intravenous Docetaxel - Mediastinal Neoplasms | Phase 2 | Terminated | Aultman Health Foundation | 7 | 2004-11-01 | 2018-08-20 |
Mediastinal Neoplasms (7) · Thymoma (2) · Agnosia (1) · Bacteremia (1) · Breast Neoplasms (1) · Carcinoma, Non-Small-Cell Lung (1) · Cardiovascular Diseases (1) · Colonic Neoplasms (1) · Esophageal Neoplasms (1) · Genital Neoplasms, Female (1) · Genital Neoplasms, Male (1) · Lung Neoplasms (1) · Mediastinitis (1) · Neoplasms, Germ Cell and Embryonal (1)
Respiratory Tract Diseases (10) · Mediastinal Diseases (8) · Neoplasms (7) · Neoplasms by Site (7) · Thoracic Neoplasms (6) · Neoplasms by Histologic Type (4) · Digestive System Diseases (2) · Digestive System Neoplasms (2) · Gastrointestinal Diseases (2) · Gastrointestinal Neoplasms (2) · Hemic and Lymphatic Diseases (2) · Lung Diseases (2) · Lymphatic Diseases (2) · Neoplasms, Complex and Mixed (2)
130-nm albumin-bound paclitaxel (1) · Atorvastatin (1) · Bupivacaine (1) · Carboplatin (1) · Cisplatin (1) · Cyclophosphamide (1) · Docetaxel (1) · Doxorubicin (1) · Epinephrine (1) · Ethiodized Oil (1) · Iodized Oil (1) · Lisinopril (1) · Mitomycin (1) · Mitozytrex (1) · One-Lung Ventilation (1)
Aultman Health Foundation (1) · City of Hope Medical Center (1) · Massachusetts General Hospital (1) · Merck Sharp & Dohme LLC (1) · Nasser Hanna, M.D. (1) · National Cancer Institute (NCI) (1) · Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine (1) · Sun Yat-sen University (1) · UNC Lineberger Comprehensive Cancer Center (1) · Universidade do Extremo Sul Catarinense - Unidade Academica de Ciecias da Saude (1)
United States (5) · China (2) · Brazil (1)
Eduardo Balleter, MD (1) · Fan Jiang, MD, PhD (1) · Franz E Boas, MD (1) · Giuseppe Giaccone, M.D. (1) · Harald Ott, MD (1) · Hui Liu (1) · Nasser Hanna, M.D. (1) · Raza Khan, MD (1) · Shivani Sud, MD (1)
PMID 12873949, PMID 1517644, PMID 15919269, PMID 17341537, PMID 21502553, PMID 22013534, PMID 22227789, PMID 23049275, PMID 23549582, PMID 25866297, PMID 25912739, PMID 26308513, PMID 26447431, PMID 26507422, PMID 27042786, PMID 27790554, PMID 29045540, PMID 37611799, PMID 9879238
P30CA033572 (1)