6 recruiting, 4 active not recruiting, 4 completed. 8 Phase 2, 4 Phase 3, 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 8 | Active not recruiting 3, Recruiting 3, Completed 2 |
| Phase 3 | 4 | Recruiting 2, Active not recruiting 1, Completed 1 |
| Phase 1 | 3 | Recruiting 2, Completed 1 |
Follow Mitozytrex: new trials by email Literature Review of Mitozytrex trials Research Report on Mitozytrex
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pressurized Intraperitoneal Aerosolized Chemotherapy With Mitomycin for the Treatment of Unresectable Appendix or Colorectal Cancer With Peritoneal Metastases, The IMPACT Trial Bevacizumab, Biopsy Procedure, Biospecimen Collection - Metastatic Appendix Carcinoma, Metastatic Colorectal Carcinoma | Phase 3 | Recruiting | City of Hope Medical Center | 129 | 2026-10-01 | 2026-09-25 |
| Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Study Biospecimen Collection, Cisplatin, Computed Tomography - Muscle Invasive Bladder Urothelial Carcinoma, Stage II Bladder Cancer AJCC v8 | Phase 3 | Recruiting | NRG Oncology | 486 | 2025-10-07 | 2026-10-23 |
| Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial Biospecimen Collection, Cisplatin, Computed Tomography - Non-Muscle Invasive Bladder Urothelial Carcinoma, Recurrent Non-Muscle Invasive Bladder Urothelial Carcinoma | Phase 2 | Recruiting | National Cancer Institute (NCI) | 160 | 2025-06-03 | 2026-10-19 |
| In-home Intravesical Chemotherapy for the Treatment of Bladder Cancer, INVITE Trial BCG Solution, Cystoscopy, Docetaxel - Non-Muscle Invasive Bladder Carcinoma, Stage 0a Bladder Cancer AJCC v8 | Phase 1 / Phase 2 | Recruiting | Mayo Clinic | 40 | 2025-04-21 | 2026-10-08 |
| Phase II Trial of Lung Chemoemobolization Computed Tomography, Ethiodized Oil, Mitomycin - Lung Non-Small Cell Carcinoma, Mediastinal Neoplasm | Phase 2 | Recruiting | City of Hope Medical Center | 30 | 2023-05-12 | 2026-03-05 |
| Therapy Adapted for High Risk and Low Risk HIV-Associated Anal Cancer Anoscopy, Biospecimen Collection, Capecitabine - AIDS-Related Anal Carcinoma, Anal Margin Squamous Cell Carcinoma | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 40 | 2022-08-09 | 2026-10-05 |
| A Study of Chemotherapy and Radiation Therapy Compared to Chemotherapy and Radiation Therapy Plus MEDI4736 (Durvalumab) Immunotherapy for Bladder Cancer Which Has Spread to the Lymph Nodes, INSPIRE Trial Biopsy of Bladder, Biospecimen Collection, Cisplatin - Bladder Urothelial Carcinoma, Stage III Bladder Cancer AJCC v8 | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 11 | 2021-03-17 | 2026-05-22 |
| PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer Biopsy, Cisplatin, Doxorubicin - Clinical Stage IV Gastric Cancer AJCC v8, Clinical Stage IVA Gastric Cancer AJCC v8 | Phase 1 | Recruiting | City of Hope Medical Center | 49 | 2020-08-21 | 2026-08-26 |
| Lower-Dose Chemoradiation in Treating Patients With Early-Stage Anal Cancer, the DECREASE Study Biopsy, Biospecimen Collection, Capecitabine - Anal Basaloid Carcinoma, Anal Canal Cloacogenic Carcinoma | Phase 2 | Active not recruiting | ECOG-ACRIN Cancer Research Group | 252 | 2020-01-02 | 2026-10-19 |
| Chemoradiotherapy With or Without Atezolizumab in Treating Patients With Localized Muscle Invasive Bladder Cancer Atezolizumab, Biopsy of Bladder, Cisplatin - Bladder Urothelial Carcinoma, Muscle Invasive Bladder Carcinoma | Phase 3 | Active not recruiting | National Cancer Institute (NCI) | 475 | 2019-06-03 | 2026-08-28 |
| Avelumab in Combination With Fluorouracil and Mitomycin or Cisplatin and Radiation Therapy in Treating Participants With Muscle-Invasive Bladder Cancer Avelumab, Cisplatin, Fluorouracil - Bladder Carcinoma Infiltrating the Muscle of the Bladder Wall, Stage II Bladder Cancer AJCC v8 | Phase 2 | Completed | Mayo Clinic | 2 | 2018-09-19 | 2023-01-06 |
| Heated Mitomycin and Cisplatin During Surgery in Treating Patients With Stomach or Gastroesophageal Cancer Cisplatin, Hyperthermic Intraperitoneal Chemotherapy, Mitomycin - Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma | Phase 2 | Completed | M.D. Anderson Cancer Center | 24 | 2016-09-01 | 2024-09-19 |
| Chemoembolization With or Without Sorafenib Tosylate in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery Cisplatin, Computed Tomography, Doxorubicin Hydrochloride - Hepatocellular Carcinoma, Unresectable Hepatocellular Carcinoma | Phase 3 | Completed | National Cancer Institute (NCI) | 235 | 2009-10-28 | 2024-01-03 |
| Veliparib With or Without Mitomycin C in Treating Patients With Metastatic, Unresectable, or Recurrent Solid Tumors Laboratory Biomarker Analysis, Mitomycin, Veliparib - Solid Neoplasm | Phase 1 | Completed | National Cancer Institute (NCI) | 20 | 2009-10-01 | 2016-07-11 |
Urinary Bladder Neoplasms (6) · Anus Neoplasms (2) · Appendiceal Neoplasms (2) · Colorectal Neoplasms (2) · Peritoneal Neoplasms (2) · Anal Canal Carcinoma (1) · Carcinoma, Hepatocellular (1) · Carcinoma, Non-Small-Cell Lung (1) · Colonic Neoplasms (1) · HIV Infections (1) · Mediastinal Neoplasms (1) · Neoplasm Metastasis (1) · Non-Muscle Invasive Bladder Neoplasms (1) · Ovarian Neoplasms (1) · Pleural Neoplasms (1)
National Cancer Institute (NCI) (6) · City of Hope Medical Center (3) · Mayo Clinic (2) · ECOG-ACRIN Cancer Research Group (1) · M.D. Anderson Cancer Center (1) · NRG Oncology (1)
United States (14) · Canada (2)
Parminder Singh (2) · Al B Benson (1) · Brian C Baumann (1) · Brian D Badgwell (1) · Franz E Boas, MD (1) · Jennifer A Dorth (1) · Monika Joshi (1) · Mustafa Raoof (1) · Mustafa Raoof, MD (1) · Rafi Kabarriti (1) · Sameh Mikhail (1) · Scott E Delacroix (1) · Thanh H Dellinger, MD (1) · Timothy D. Lyon, MD (1)
P30CA033572 (3), U10CA180820 (3), U10CA180868 (2), N01CM00070 (1), N01CM62207 (1), P30CA016058 (1), U10CA021115 (1), U10CA180888 (1), UL1TR002377 (1), UM1CA121947 (1)