23 completed, 14 unknown, 7 recruiting, 5 not yet recruiting. 24 Not applicable, 8 Phase 2, 5 Phase 3, 5 Phase 4.
Follow Mediastinal Diseases: new trials by email Literature Review of Mediastinal Diseases trials Research Report on Mediastinal Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Difficult Airway Management in Oncology: An International Delphi Consensus Study (DAMO) Questionnaire Administration - Neoplasms, Airway Obstruction Upper | Enrolling by invitation | Onco Critical Care Society | 40 | 2026-08-19 | 2026-10-01 | |
| Pharmacologic Therapies to Mitigate Radiation- Associated Heart Disease Atorvastatin and Lisinopril, Placebo - Chest Wall Tumor, Breast Cancer | Phase 2 | Recruiting | UNC Lineberger Comprehensive Cancer Center | 60 | 2026-08-12 | 2026-09-17 |
| Innovative Sternal Closure Techniques: Evaluating STRATAFIX™ and DERMABOND™ for Reduced Complications in CABG Patients Knotless Barbed Sutures, Mesh-based Topical Skin Adhesive - Cardiovascular Disease, Surgical Site Infection | Phase 4 | Not yet recruiting | Unity Health Toronto | 401 | 2026-05-01 | 2026-04-13 |
| Delafloxacin Plasma and Tissue Concentration in Patients With Skin, Soft Tissue, and Bone and Joint Infections. delafloxacin - Soft Tissue Infections, Mediastinitis | Not yet recruiting | IRCCS San Raffaele | 20 | 2026-04-01 | 2026-02-23 | |
| 6 vs 3 Cycles of Neoadjuvant Chemotherapy for Potentially Resectable Locally Advanced Thymic Epithelial Tumors Cyclophosphamide, Doxorubicin, and Cisplatin (CAP), nab-Paclitaxel and Carboplatin - Thymoma and Thymic Carcinoma | Phase 2 / Phase 3 | Not yet recruiting | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 116 | 2026-03-01 | 2026-03-11 |
| Antibiotics Distribution Study in Peripheral Compartments: Contribution of Microdialysis Microdialysis probe placement, Microdialysis and Plasma samples - Children in Cardiac Intensive Care Requiring Surgery for Congenital Heart Disease | Not applicable | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 10 | 2026-01-01 | 2026-01-08 |
| 22G-Adapt vs 22G-Franseen Needle Biopsy in EUS-Guided Tissue Acquisition of Solid Lesions 22G Franseen Needle Group, 22G Adapt Needle Group - Pancreatic Neoplasms, Mediastinal Neoplasms | Not applicable | Not yet recruiting | Huazhong University of Science and Technology | 576 | 2025-07-01 | 2025-07-01 |
| The Role of Inflammatory Biomarkers in Preventing Deep Sternal Wound Infections After Sternotomy Deep Sternal Infection, Diabete Mellitus | Active not recruiting | Levan Nebieridze | 30 | 2025-04-14 | 2026-01-29 | |
| Tubeless VATS for Mediastinal Neoplasm Non-intubated VATS for mediastinal neoplasm, Intubated VATS for mediastinal neoplasm - Mediastinal Neoplasm, VATS | Not applicable | Recruiting | Shuben Li | 132 | 2025-03-26 | 2025-07-15 |
| Validation of an AI-Assisted Mediastinal EUS System for Training Improvement: a Prospective, Multi-Center, Randomized Trial Artificial intelligence device - Mediastinal Disease | Not applicable | Recruiting | The Third Xiangya Hospital of Central South University | 200 | 2025-01-15 | 2025-01-23 |
| 22G-Adapt Needle Biopsy Versus Fine-needle Aspiration in Endoscopic Ultrasound-guided Sampling of Solid Lesions FNA group, Adapt FNB group - Pancreatic Neoplasms, Mediastinal Neoplasms | Not applicable | Unknown | Huazhong University of Science and Technology | 656 | 2024-09-01 | 2024-08-20 |
| Pilot Study of LED for PIE and PIH LED, without any LED exposition - Hyperpigmentation | Not applicable | Unknown | Yanjun Dan | 10 | 2024-04-10 | 2024-04-05 |
| Lateral Approach for Mediastinal Lymph Node Dissection in Thyroid Cancer Thyroid Cancer, Mediastinal Diseases | Completed | Chongqing General Hospital | 21 | 2024-01-01 | 2025-01-27 | |
| Phase II Trial of Lung Chemoemobolization Computed Tomography, Ethiodized Oil, Mitomycin - Lung Non-Small Cell Carcinoma, Mediastinal Neoplasm | Phase 2 | Recruiting | City of Hope Medical Center | 30 | 2023-05-12 | 2026-03-05 |
| Clinical Investigation of the da Vinci Surgical System Robotic-assisted Surgery - Thymoma, Mediastinal Tumor | Not applicable | Active not recruiting | Intuitive Surgical | 53 | 2022-12-12 | 2024-06-03 |
| Use of Platelet-Rich Plasma to Reduce Sternal Wound Complications After CABG With Median Sternotomy Autologous Platelet-Rich Plasma (PRP) Application, Standard Sternal Wound Closure - Surgical Site Infection (SSI), Mediastinitis | Not applicable | Completed | Shaheed Zulfiqar Ali Bhutto Medical University | 98 | 2022-07-07 | 2026-01-27 |
| Diagnostic Yield of Intranodal Forceps Biopsies in Mediastinal Adenopathy Endobronchial Ultrasound-Guided Intranodal Forceps Biopsy - Mediastinal Lymphadenopathy, Sarcoidosis, Pulmonary | Not applicable | Completed | George Washington University | 55 | 2022-06-10 | 2026-04-14 |
| Clinical Impact of Thoracic Scanographic Characteristics of Hematologic Malignancy Patients analysis of thoracic scans - Mediastinal Diseases | Unknown | University Hospital, Toulouse | 125 | 2022-06-01 | 2024-09-25 | |
| Effects of Oral Aloe Vera Juice on Chemotherapy and Radiation-induced Oral Mucositis and Esophagitis 100% Aloe Vera Juice, Magic Mouthwash, Salt and Baking soda rinse - Oral Cavity Cancer, Head and Neck Cancers - Tonsils | Phase 3 | Completed | Covenant Health Cancer Center | 100 | 2022-01-20 | 2024-10-10 |
| Diagnosis and Comprehensive Treatment of Mediastinal Interventional Technique Intraairway ultrasound-guided mediastinal opening technique, Transbronchial Lung Biopsy (TBLB) - Mediastinal Diseases | Recruiting | Dan Liu | 30 | 2021-12-01 | 2026-02-10 |
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Mediastinal Neoplasms (21) · Mediastinitis (21) · Mediastinal Emphysema (5) · Pneumothorax (4) · Thymoma (4) · Cardiovascular Diseases (3) · Esophageal Neoplasms (3) · Lung Neoplasms (3) · Surgical Wound Infection (3) · Abdominal Neoplasms (2) · Coronary Artery Disease (2) · Cross Infection (2) · Hemorrhage (2) · Hypoxia (2)
Respiratory Tract Diseases (56) · Thoracic Diseases (56) · Neoplasms (23) · Neoplasms by Site (23) · Pathological Conditions, Signs and Symptoms (19) · Thoracic Neoplasms (19) · Pathologic Processes (16) · Lung Diseases (11) · Infections (9) · Neoplasms by Histologic Type (9) · Hemic and Lymphatic Diseases (8) · Lymphatic Diseases (8) · Digestive System Diseases (7) · Endocrine System Diseases (7)
Cisplatin (2) · Cyclophosphamide (2) · Doxorubicin (2) · Etoposide (2) · Ifosfamide (2) · 130-nm albumin-bound paclitaxel (1) · Atorvastatin (1) · Bleomycin (1) · Bone Wires (1) · Bronchoscopy (1) · Carboplatin (1) · Caregivers (1) · Cytarabine (1) · Daptomycin (1) · Dexamethasone (1)
Huazhong University of Science and Technology (2) · Tel-Aviv Sourasky Medical Center (2) · The Third Xiangya Hospital of Central South University (2) · Assistance Publique - Hôpitaux de Paris (1) · Assiut University (1) · Aultman Health Foundation (1) · Azienda Sanitaria-Universitaria Integrata di Udine (1) · Cairo University (1) · Chongqing General Hospital (1) · City of Hope Medical Center (1) · Clinical Center of Vojvodina (1) · Covenant Health Cancer Center (1) · Dan Liu (1) · Dr. Donald Likosky (1) · Duke University (1)
China (14) · United States (13) · France (5) · Germany (4) · Belgium (2) · Egypt (2) · Israel (2) · Italy (2) · Switzerland (2) · Taiwan (2) · Austria (1) · Canada (1) · Denmark (1) · Georgia (1) · India (1)
Bin Cheng (2) · Donald S Likosky, Ph.D. (2) · Idit Matot, MD (2) · Patrick Sorkine, MD (2) · Xiaoyan Wang, Doctor (2) · Alain Tremblay, MDCM (1) · Aleksandar Kiralj, PhD (1) · Brian DeGuzmann, MD (1) · Chiu-kuei Nien (1) · Cristiane D Goncalves, FT (1) · Daniel Scaperoth, MD (1) · Dima Shmain, MD (1) · Elliott Bennett-Guerrero, M. D. (1) · Fan Jiang, MD, PhD (1)
PMID 28733257, PMID 31654634, PMID 32526235, PMID 32583392, PMID 34535035, PMID 35124072, PMID 11383846, PMID 13129420, PMID 16055882, PMID 16305872, PMID 17768574, PMID 17934967, PMID 18047460, PMID 18760163, PMID 18952475, PMID 19188547, PMID 19272785, PMID 19303579, PMID 19456845, PMID 19879566, PMID 20084586, PMID 20117014, PMID 20625667, PMID 21059637, PMID 21502553, PMID 21529357, PMID 21820786, PMID 23433878, PMID 23549582, PMID 23761413, PMID 24987052, PMID 25359988, PMID 26321440, PMID 26693152, PMID 26762737, PMID 26829352, PMID 26904425, PMID 27134844, PMID 27261082, PMID 27621880, PMID 27686131, PMID 28007878, PMID 29045540, PMID 29078440, PMID 29078441, PMID 29078536, PMID 29078668, PMID 29174785, PMID 29682455, PMID 29701369
2025 (1), P30CA033572 (1)