16 completed. 16 Phase 1, 6 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 16 | Completed 16 |
| Phase 2 | 6 | Completed 6 |
Follow Tetanus: new trials by email Literature Review of Tetanus trials Research Report on Tetanus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SNA02-48 Injection in Chinese Adult Participants SNA02-48, Placebo, HTIG - Tetanus | Phase 1 / Phase 2 | Completed | Sinovac Life Sciences Co., Ltd. | 255 | 2025-04-28 | 2026-06-03 |
| A Study to Evaluate the Safety and Immunogenicity of a Single Dose of Adsorbed Tetanus Vaccine in a Population Aged 18 Years and Over TTVA, TT - Tetanus | Phase 1 | Completed | CanSino Biologics Inc. | 60 | 2023-12-20 | 2024-11-29 |
| A Clinical Trial of Adsorbed Cell-free DPT Vaccine (5-component) (for People Aged 6 Years and Above) Tetanus, Reduced Diphtheria and Acellular Pertussis (Five Components) Combined Vaccine, Adsorbed (Aged 6 Years and Older) (Tdcp), 23-Valent Pneumococcal Polysaccharide Vaccine（PPV23）, Diphtheria and Tetanus Combined Vaccine, Adsorbed (DT) - Diphtheria, Tetanus | Phase 1 | Completed | CanSino Biologics Inc. | 180 | 2023-12-06 | 2026-08-07 |
| Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Immunogenicity of GR2001 in Chinese Healthy Adults GR2001, Placebo, HTIG - Tetanus | Phase 1 / Phase 2 | Completed | Genrix (Shanghai) Biopharmaceutical Co., Ltd. | 202 | 2023-03-04 | 2024-03-08 |
| A Randomized, Open-Label, Parallel-Design Pharmacokinetic and Pharmacodynamic Interaction Study of TNM002 and Adsorbed Tetanus Vaccine TNM002, Adsorbed tetanus vaccine, TNM002 + adsorbed tetanus vaccine - Tetanus | Phase 1 | Completed | Zhuhai Trinomab Pharmaceutical Co., Ltd. | 60 | 2022-08-13 | 2024-09-23 |
| Phase I Clinical Trial of Diphtheria, Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed . Diphtheria,Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed, Diphtheria and Tetanus Combined Vaccine, Adsorbed, Diphtheria-tetanus-acellular pertussis vaccine - Diphtheria, Tetanus | Phase 1 | Completed | CanSino Biologics Inc. | 400 | 2020-04-28 | 2022-10-31 |
| A Study to Compare LBVD to Eupenta and Imovax Polio in Healthy Adults DTP-HepB-IPV-Hib vaccine, DTP-HepB-Hib vaccine & IPV - Diphtheria, Tetanus | Phase 1 | Completed | LG Chem | 42 | 2017-07-03 | 2019-08-29 |
| A Study of AV0328 Administered to Healthy Adult Volunteers AV0328 - Cohort 1, AV0328 - Cohort 2, AV0328 - Cohort 3 - PNAG-expressing Pathogenic Microbes Vaccine | Phase 1 / Phase 2 | Completed | Alopexx Vaccine, LLC | 16 | 2017-03-22 | 2019-03-19 |
| Intrathecal Tetanus Immunoglobulin to Treat Tetanus Human tetanus immunoglobulin, Intramuscular antitoxin - Tetanus | Phase 1 / Phase 2 | Completed | Oxford University Clinical Research Unit, Vietnam | 272 | 2017-02-13 | 2020-05-29 |
| Safety and Efficacy of Two Tetanus-Diphtheria Vaccines for a Donor Hyper Immunization Program Tetanus and Diphtheria (Td) Vaccine - Healthy | Phase 1 | Completed | Biomat USA, Inc. | 300 | 2016-08-22 | 2021-07-20 |
| Study of Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis Vaccine Adsorbed in Healthy Subjects Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis Vaccine Adsorbed Formulation 1, Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis Vaccine Adsorbed, Formulation 2, Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis Vaccine Adsorbed, Formulation 3 - Tetanus, Diphtheria | Phase 1 / Phase 2 | Completed | Sanofi Pasteur, a Sanofi Company | 1363 | 2015-10-22 | 2022-03-23 |
| Study of the Tdap Combined Vaccine (ADACEL™) as a Booster Dose in Healthy Adults and Children in China Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine Adsorbed Tdap - Diphtheria, Tetanus | Phase 1 | Completed | Sanofi Pasteur, a Sanofi Company | 40 | 2013-08-01 | 2016-03-07 |
| Study of Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine (ADACEL®) as a Booster in Adolescents (ADACEL®): Tetanus, Reduced Diphtheria Toxoid and Acellular Pertussis - Pertussis, Tetanus | Phase 1 / Phase 2 | Completed | Sanofi Pasteur, a Sanofi Company | 43 | 2012-09-01 | 2014-02-21 |
| Safety and Dose Ranging Study of Acellular Pertussis and Acellular Pertussis -Tetanus-Diphtheria Booster Vaccines in Healthy Adults Ages 18 to 40 Years Acellular pertussis vaccine, Tetanus, reduced diphtheria, and acellular pertussis vaccine (adsorbed), Licensed TdaP booster vaccine - Pertussis, Whooping Cough | Phase 1 | Completed | Novartis Vaccines | 420 | 2012-03-01 | 2016-04-04 |
| Pertussis Vaccine in Healthy Pregnant Women Placebo, Tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine adsorbed - Diphtheria, Pertussis | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 80 | 2009-01-01 | 2014-07-25 |
| Vaccination for Middle Ear Infection Nontypeable Haemophilus influenzae - Otitis Media | Phase 1 | Completed | National Institute on Deafness and Other Communication Disorders (NIDCD) | 40 | 1997-05-01 | 2008-03-04 |
Diphtheria (8) · Whooping Cough (8) · Haemophilus Infections (1) · Hepatitis B (1) · Infections (1) · Otitis Media (1) · Poliomyelitis (1) · Trismus (1)
Bacterial Infections (16) · Bacterial Infections and Mycoses (16) · Clostridium Infections (16) · Gram-Positive Bacterial Infections (16) · Infections (15) · Actinomycetales Infections (8) · Bordetella Infections (8) · Corynebacterium Infections (8) · Gram-Negative Bacterial Infections (8) · Respiratory Tract Diseases (8) · Respiratory Tract Infections (8) · Nervous System Diseases (2) · Blood-Borne Infections (1) · Central Nervous System Diseases (1) · Central Nervous System Infections (1)
Tetanus Toxoid (9) · Vaccines, Combined (2) · adacel (2) · Aging (1) · Diphtheria-Tetanus-acellular Pertussis Vaccines (1) · Drug Evaluation (1) · Poliovirus Vaccine, Inactivated (1) · Saline Solution (1) · Vaccines (1) · ompP2 protein, Haemophilus influenzae (1)
CanSino Biologics Inc. (3) · Sanofi Pasteur, a Sanofi Company (3) · Alopexx Vaccine, LLC (1) · Biomat USA, Inc. (1) · Genrix (Shanghai) Biopharmaceutical Co., Ltd. (1) · LG Chem (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · National Institute on Deafness and Other Communication Disorders (NIDCD) (1) · Novartis Vaccines (1) · Oxford University Clinical Research Unit, Vietnam (1) · Sinovac Life Sciences Co., Ltd. (1) · Zhuhai Trinomab Pharmaceutical Co., Ltd. (1)
China (7) · United States (5) · Belgium (1) · Japan (1) · South Korea (1) · Vietnam (1)
Geert Leroux-Roels, Prof. Dr. (1) · Hal Landy, MD (1) · Jie Hou, Doctor (1) · Jing Zhang, PHD (1) · Marilyn Rosa-Bray, MD (1) · Minh Yen Lam, MD (1) · Shiguang Lei (1) · WJ Kim (1) · Wang Yanxia (1) · Wei Hu (1)
PMID 24794369, PMID 29172945, PMID 30809591, PMID 35561721, PMID 40977696