11 completed, 2 active not recruiting, 2 withdrawn, 1 not yet recruiting. 6 Phase 2, 3 Not applicable, 3 Phase 1, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 5, Withdrawn 1 |
| Not applicable | 3 | Active not recruiting 1, Completed 1, Withdrawn 1 |
| Phase 1 | 3 | Completed 2, Terminated 1 |
| Phase 3 | 1 | Completed 1 |
| Phase 4 | 1 | Completed 1 |
Follow Sturge-Weber Syndrome: new trials by email Literature Review of Sturge-Weber Syndrome trials Research Report on Sturge-Weber Syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Neurocutaneous Syndromes in Children: Prevalence and Clinical Characteristics Sturge-Weber Syndrome, Neurocutaneous Syndromes | Not yet recruiting | Assiut University | 100 | 2026-09-20 | 2026-09-28 | |
| Safety and Tolerability Study of QLS-101 in Adolescents With Sturge-Weber Syndrome (SWS)-Related Glaucoma Due to Elevated Episcleral Venous Pressure (EVP) QLS-101 ophthalmic solution, 2.0 % - Sturge-Weber Syndrome, Glaucoma | Phase 2 | Completed | Qlaris Bio, Inc. | 2 | 2022-11-23 | 2025-01-20 |
| A Study to Determine the Safety and Tolerability of 2 Concentrations of QLS-101 QLS-101ophthalmic solution 1%, QLS-101ophthalmic solution 2% - Sturge-Weber Syndrome (SWS), Glaucoma | Phase 2 | Completed | Qlaris Bio, Inc. | 3 | 2021-10-19 | 2025-01-20 |
| Longitudinal Studies to Identify Biomarkers for Sturge-Weber Syndrome Sturge-Weber Syndrome | Completed | University of Illinois at Chicago | 161 | 2021-09-08 | 2026-07-07 | |
| Longitudinal Neuroimaging in Sturge-Weber Syndrome Brain magnetic resonance imaging, Neuro-psychology testing - Sturge-Weber Syndrome | Not applicable | Active not recruiting | Wayne State University | 80 | 2020-03-01 | 2026-08-19 |
| A New Approach in Laser Surgery Using the Regenerative Solution in Children Diagnosed With Vascular Pathology Haemoblock, Placebo - Vascular Diseases, Vascular Malformation | Phase 4 | Completed | Center for Vascular Pathology, Moscow | 200 | 2020-01-01 | 2021-11-04 |
| Novel Cognitive Treatment Targets for Epidiolex in Sturge- Weber Syndrome Cannabidiol - Sturge-Weber Syndrome | Phase 2 | Completed | Anne Comi, MD | 11 | 2019-10-14 | 2023-05-25 |
| Use of a Tonometer to Identify Epileptogenic Lesions During Pediatric Epilepsy Surgery Intra-operative brain tonometry - Epilepsy, Focal Cortical Dysplasia | Not applicable | Withdrawn | University of California, Los Angeles | 2018-07-16 | 2023-10-10 | |
| Trial of Sirolimus for Cognitive Impairment in Sturge-Weber Syndrome Sirolimus - Sturge-Weber Syndrome | Phase 2 / Phase 3 | Completed | Anne Comi, MD | 10 | 2017-01-01 | 2021-11-01 |
| Cannabidiol Expanded Access Study in Medically Refractory Sturge-Weber Syndrome Cannabidiol - Sturge-Weber Syndrome | Phase 1 / Phase 2 | Completed | Anne Comi, MD | 5 | 2014-12-01 | 2022-03-02 |
| Adjunctive Everolimus (RAD 001) Therapy for Epilepsy in Children With Sturge-Weber Syndrome (SWS) Everolimus - Sturge Weber Syndrome | Phase 2 | Withdrawn | Baylor College of Medicine | 2014-04-01 | 2016-05-05 | |
| Treatment of Port-wine Mark in Sturge-Weber Syndrome Using Topical Timolol Timolol, Preservative free artificial tear gel. - Sturge Weber Syndrome, Port-wine Mark | Phase 1 | Terminated | Wills Eye | 3 | 2012-02-01 | 2019-03-21 |
| French National Cohort of Children With Port Wine Stain search for polymorphisms of RASA1 gene - Port Wine Stain, Klippel Trenaunay Syndrome | Not applicable | Completed | University Hospital, Tours | 150 | 2010-11-01 | 2025-12-22 |
| Innovative Approaches to Gauge Progression of Sturge-Weber Syndrome Sturge-Weber Syndrome | Active not recruiting | Hugo W. Moser Research Institute at Kennedy Krieger, Inc. | 600 | 2010-09-01 | 2026-03-02 | |
| Biomarker Development in Sturge-Weber Syndrome Sturge-Weber Syndrome | Completed | Hugo W. Moser Research Institute at Kennedy Krieger, Inc. | 40 | 2010-07-01 | 2020-04-16 | |
| Use of the Atkins Diet for Children With Sturge Weber Syndrome modified Atkins diet - Epilepsy, Sturge Weber Syndrome | Phase 1 | Completed | Johns Hopkins University | 5 | 2006-05-01 | 2010-05-27 |
| Precision Medicine for Neurocutaneous Syndromes in Western China Neurocutaneous Syndromes, Neurofibromatosis Type 1 (NF1) | Completed | West China Hospital | 1200 | 2000-01-01 | 2026-01-09 |
Epilepsy (3) · Glaucoma (3) · Port-Wine Stain (3) · Tuberous Sclerosis (3) · Cognitive Dysfunction (2) · Neurocutaneous Syndromes (2) · Neurofibromatosis 1 (2) · Ocular Hypertension (2) · Brain Neoplasms (1) · Capillary Malformation-Arteriovenous Malformation (1) · Capillary Malformations, Congenital, 1 (1) · Drug Resistant Epilepsy (1) · Encephalitis (1) · Focal Cortical Dysplasia (1)
Angiomatosis (17) · Cardiovascular Diseases (17) · Hemangioma (17) · Neoplasms (17) · Neoplasms by Histologic Type (17) · Neoplasms, Vascular Tissue (17) · Nervous System Diseases (17) · Vascular Diseases (16) · Neurocutaneous Syndromes (15) · Congenital Abnormalities (7) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (7) · Skin Abnormalities (5) · Skin Diseases (5) · Skin and Connective Tissue Diseases (5) · Brain Diseases (4)
Cannabidiol (2) · Everolimus (1) · Sirolimus (1) · Timolol (1)
Anne Comi, MD (3) · Hugo W. Moser Research Institute at Kennedy Krieger, Inc. (2) · Qlaris Bio, Inc. (2) · Assiut University (1) · Baylor College of Medicine (1) · Center for Vascular Pathology, Moscow (1) · Johns Hopkins University (1) · University Hospital, Tours (1) · University of California, Los Angeles (1) · University of Illinois at Chicago (1) · Wayne State University (1) · West China Hospital (1) · Wills Eye (1)
United States (13) · Canada (1) · China (1) · France (1) · Russia (1)
Anne M Comi, M.D. (3) · Anne M Comi, MD (2) · Alex V Levin, MD, MHSc (1) · Alexander Plotkin, PhD (1) · Angus A Wilfong, MD (1) · Aria Fallah, MD (1) · B. Wirostko, M.D. (1) · Dmitry V Romanov, MD (1) · Ekaterina M Listovskaya, BSc (1) · Eric H Kossoff, MD (1) · Jeffrey Loeb, MD, PhD (1) · Sharon Freedman, M.D. (1)
U54NS065705 (3)