6 completed, 4 recruiting, 2 unknown, 2 withdrawn. 6 Not applicable, 3 Phase 2, 2 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Recruiting 3, Completed 2, Withdrawn 1 |
| Phase 2 | 3 | Completed 1, Recruiting 1, Unknown 1 |
| Phase 3 | 2 | Completed 1, Terminated 1 |
| Phase 4 | 1 | Completed 1 |
Follow Capillary Malformations, Congenital, 1: new trials by email Literature Review of Capillary Malformations, Congenital, 1 trials Research Report on Capillary Malformations, Congenital, 1
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Surgery for Thumb Base Osteoarthritis: Joint Replacement vs. Trapeziectomy Implantation of trapeziometacarpal prosthesis, Trapeziectomy with Capsuloplasty - Thumb Osteoarthritis, Thumb Carpometacarpal Joint Osteoarthritis | Not applicable | Recruiting | Uppsala University | 84 | 2026-09-04 | 2026-10-09 |
| Comparative of Sequential Application of Pulsed Dye Laser and Potassium-titanyl-phosphate Laser Treatment for Capillary Malformations Versus Single Application Pulsed dye laser (PDL), Potassium titanyl phosphate (KTP) laser, Sequential KTP + PDL laser treatment - Port-Wine Stains (Capillary Malformations) | Not applicable | Recruiting | Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal | 30 | 2024-12-01 | 2025-06-11 |
| Woodcasting Versus Thermoplast Splint in CMC Arthroplasty Woodcasting Splint, Control (Standard treatment) - Carpometacarpal (CMC) Joint Arthritis | Not applicable | Recruiting | Foundation for Orthopaedic Research and Education | 26 | 2024-10-03 | 2026-09-25 |
| The Correlation of Clinical and Ultrasonographic Findings in Dorsoradial Wrist Pain Patients: Cross Sectional Study ultrasonographic examination - Carpometacarpal (CMC) Joint Arthritis, Ganglion Cyst | Completed | Fatih Sultan Mehmet Training and Research Hospital | 45 | 2024-07-29 | 2025-05-20 | |
| Randomized Placebo Controlled Study of Triamcinolone Acetonide Extended Release Injection for Thumb (CMC) Osteoarthritis Triamcinolone Acetonide extended release suspension - Carpometacarpal (CMC) Osteoarthritis | Phase 2 | Recruiting | Marie Badalamente | 30 | 2023-11-21 | 2024-02-01 |
| A New Approach in Laser Surgery Using the Regenerative Solution in Children Diagnosed With Vascular Pathology Haemoblock, Placebo - Vascular Diseases, Vascular Malformation | Phase 4 | Completed | Center for Vascular Pathology, Moscow | 200 | 2020-01-01 | 2021-11-04 |
| Mini TightRope Suspensionplasty Versus Ligament Reconstruction and Tendon Interposition for Thumb Carpometacarpal Osteoarthritis Mini tightrope suspensionplasty, Ligament Reconstruction and Tendon Interposition (LRTI) - Carpometacarpal (CMC) Joint Arthritis | Not applicable | Completed | Theodoros Mylonas | 50 | 2020-01-01 | 2026-07-13 |
| Electrosclerotherapy for Capillary Malformations Electrosclerotherapy, Intralesional bleomycin injection - Capillary Malformations, Vascular Malformations | Phase 2 | Unknown | Sophie Horbach | 20 | 2016-11-01 | 2017-06-27 |
| Onreltea (Brimonidine) Gel In Pediatric Patients With Capillary Malformations Brimonidine 0.33% gel - Capillary Malformations | Phase 3 | Terminated | The Hospital for Sick Children | 6 | 2016-06-01 | 2019-04-16 |
| Oval-8 Splinting Versus Standardized Treatment With Tee Pee or Forearm Based Thumb Spica Splinting Oval-8 Splint, Tee Pee Splint, Forearm Based Splint - Carpometacarpal (CMC) Joint Arthritis | Not applicable | Withdrawn | University of Florida | 2016-01-01 | 2016-11-04 | |
| Effect of Laser Treatment on Capillary Malformations Capillary Malformation, Port Wine Stain | Withdrawn | Children's Hospital Medical Center, Cincinnati | 2014-01-01 | 2015-08-25 | ||
| Occupational Therapy and Surgery in Carpometacarpal Osteoarthritis Care as usual, Occupational therapy - Osteoarthritis in the Carpometacarpal (CMC) Joint | Not applicable | Completed | National Resource Center for Rehabilitation in Rheumatology | 180 | 2013-04-01 | 2018-08-31 |
| Assessing the Effects of Air-cooling on Capillary Malformations Air cooling to CM site - Capillary Malformation, Laser | Unknown | National Health Service, United Kingdom | 35 | 2013-02-01 | 2012-11-28 | |
| CMC-1 Replacement Arthroplasty Versus Trapeziectomy Osteoarthritis in the Carpometacarpal (CMC) Joint | Completed | Karolinska Institutet | 1000 | 2011-01-01 | 2026-05-13 | |
| Double-Blind,Randomized,Placebo-Controlled Efficacy & Safety Study of EUFLEXXA™ for Treatment of OA of the First CMC sodium hyaluronate, placebo - Osteoarthritis | Phase 2 / Phase 3 | Completed | Ferring Pharmaceuticals | 79 | 2006-12-01 | 2011-05-19 |
Osteoarthritis (4) · Port-Wine Stain (4) · Vascular Malformations (2) · Capillary Malformation-Arteriovenous Malformation (1) · De Quervain Disease (1) · Ganglion Cysts (1) · Radial Neuropathy (1) · Skin Diseases (1) · Sturge-Weber Syndrome (1) · Vascular Diseases (1) · Vascular Neoplasms (1)
Skin and Connective Tissue Diseases (6) · Congenital Abnormalities (5) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (5) · Musculoskeletal Diseases (5) · Arthritis (4) · Joint Diseases (4) · Rheumatic Diseases (4) · Skin Abnormalities (4) · Skin Diseases (4) · Cardiovascular Abnormalities (2) · Cardiovascular Diseases (2) · Neoplasms (2) · Nervous System Diseases (2) · Angiomatosis (1) · Connective Tissue Diseases (1)
Brimonidine Tartrate (1) · Electrochemotherapy (1) · Gels (1) · Lasers (1) · Lasers, Dye (1) · Occupational Therapy (1)
Center for Vascular Pathology, Moscow (1) · Children's Hospital Medical Center, Cincinnati (1) · Fatih Sultan Mehmet Training and Research Hospital (1) · Ferring Pharmaceuticals (1) · Foundation for Orthopaedic Research and Education (1) · Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal (1) · Karolinska Institutet (1) · Marie Badalamente (1) · National Health Service, United Kingdom (1) · National Resource Center for Rehabilitation in Rheumatology (1) · Sophie Horbach (1) · The Hospital for Sick Children (1) · Theodoros Mylonas (1) · University of Florida (1) · Uppsala University (1)
United States (5) · Canada (1) · Greece (1) · Netherlands (1) · Norway (1) · Russia (1) · Spain (1) · Sweden (1) · Turkey (Türkiye) (1) · United Kingdom (1)
Adam Gilmour, MBChB, MRCS (Ed) (1) · Adrienne Hammill, MD, PhD (1) · Alexander Plotkin, PhD (1) · Dmitry V Romanov, MD (1) · Ekaterina M Listovskaya, BSc (1) · Elena Pope, MD (1) · Esra Giray, Associated Professor (1) · Feyza Unlu Ozkan, Professor (1) · Iain Mackay, MBChb, MRCS, FRCS (plast) (1) · Ilknur Aktas, Professor (1) · Irving Ling, MBBS (1)
PMID 29138199, PMID 31574025, PMID 33338325, PMID 37355263, PMID 41656908