15 completed, 5 unknown, 3 not yet recruiting, 1 recruiting. 26 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 26 | Completed 15, Unknown 5, Not yet recruiting 3, Recruiting 1, Terminated 1, Withdrawn 1 |
Follow Stomatitis, Aphthous: new trials by email Literature Review of Stomatitis, Aphthous trials Research Report on Stomatitis, Aphthous
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Sesame Paste for Recurrent Aphthous Stomatitis Sesame paste, Placebo - Recurrent Aphthous Stomatitis | Not applicable | Not yet recruiting | Ayat Gamal-AbdelNaser | 46 | 2026-12-01 | 2026-10-01 |
| Improving Prescribing Quality for Oral Mucosal Disorders Using a Pharmacist-Led Model Pharmacist-Led Prescribing Optimization and Patient Counselling - Oral Lichen Planus, Recurrent Aphthous Stomatitis | Not applicable | Not yet recruiting | University of Fujairah | 336 | 2026-07-01 | 2026-07-22 |
| The Preventive and Therapeutic Effects of Spirulina Preparations on Ulcers of Oral Mucosa Spirulina Tablets, Placebo Tablets - Recurrent Aphthous Stomatitis, Mouth Ulcer | Not applicable | Recruiting | The Fourth Affiliated Hospital of Zhejiang University School of Medicine | 40 | 2026-06-01 | 2026-07-23 |
| Efficacy and Safety of Thalidomide for Pediatric PFAPA Syndrome Thalidomide (50mg), Colchicine - Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis Syndrome | Not applicable | Not yet recruiting | Wenjie Zheng | 106 | 2026-04-01 | 2026-03-17 |
| Comparison of Hypericum Perforatum, Topical Corticosteroids, and Hyaluronic Acid for Recurrent Aphthous Stomatitis Kenacort A Orabase® pomad , Bristol-Myers Squibb İlaçları Inc. İstanbul , Türkiye, Hyaluronic acid, Aftamed ® Oral jel , AktiFarma . İstanbul, Türkiye, Hypericum perforatum (St. John's wort oil, Zade Vital; Health&Fitness, Developed With Ege Üniversiesi Argefar) - Stomatitis, Aphthous | Not applicable | Completed | Batman University | 75 | 2025-02-01 | 2026-07-08 |
| Efficacy of Photobiomodulation in the Treatment and Relief of Pain in Recurrent Aphthous Stomatitis Gemini laser, Placebo - Photobiomodulation, Stomatitis, Aphthous | Not applicable | Unknown | Federal University of Rio Grande do Sul | 34 | 2024-07-01 | 2024-05-16 |
| Efficacy of Thyme Honey in The Management of Oral Aphthous Ulcers Thyme honey, Kenalog - Aphthous Stomatitis (Major) (Minor), Treatment Compliance | Not applicable | Unknown | British University In Egypt | 20 | 2024-05-10 | 2024-05-20 |
| Efficacy and Safety of BNP105 in the Treatment of Recurrent Aphthous Stomatitis BNP105 (25 + 25 + 15), Placebo - Aphthous Stomatitis | Not applicable | Unknown | EMS | 102 | 2024-01-22 | 2024-02-20 |
| A Study on Sumac Mouth Rinse for Treating Recurrent Aphthous Stomatitis Sumac mouth rinse, Tantum Verde mouth rinse - Recurrent Aphthous Stomatitis | Not applicable | Completed | Ain Shams University | 38 | 2023-12-20 | 2026-05-08 |
| Effectiveness of Recurrent Aphthous Stomatitis Mouthwash System for the Treatment of Oral Ulcers Mouthwash Product, Control - Recurrent Aphthous Ulcer, Recurrent Aphthous Stomatitis | Not applicable | Completed | G. d'Annunzio University | 60 | 2023-11-28 | 2025-08-13 |
| The Efficacy of Nigella Sativa Oil Mouth Rinse in the Management of Recurrent Minor Aphthous Ulcer Nigella Sativa Oil Mouth Rinse, isotonic (normal saline) with concentration 0.90% of sodium chloride (NaCl) - Aphthous Ulcer | Not applicable | Unknown | Nada Sherif | 20 | 2023-09-22 | 2023-08-29 |
| Devintec OR-AT0222 Oral Gel for the Treatment of Canker Sores: A Double Blind, Randomized, Placebo Controlled Clinical Investigation OR-AT0222, Placebo - Recurrent Aphthous Ulcer | Not applicable | Unknown | Devintec Sagl | 46 | 2023-05-08 | 2023-07-25 |
| Post-marketing Study for the Evaluation of Profilm Mouth Sores Profilm Mouth Sores - Mouth Sores | Not applicable | Completed | i+Med S.Coop. | 35 | 2022-12-13 | 2025-04-25 |
| Luminance RED for Canker Sores Luminance RED Low Level Laser Therapy Device - Canker Sore | Not applicable | Withdrawn | ProofPilot | 2021-06-21 | 2026-09-17 | |
| Non-Thermal Plasma vs. Low-Level Laser Therapy for Recurrent Oral Ulcers Non-Thermal Plasma (NTP), Low-Level Laser Therapy (LLLT), Placebo - Stomatitis, Aphthous Ulcer | Not applicable | Completed | National Institute of Nuclear Research - Mexico | 50 | 2019-02-04 | 2026-01-07 |
| Curcumin and Nanocurcumin in Oral Aphthous Ulcer Gel - Recurrent Aphthous Ulcer, Recurrent Aphthous Stomatitis | Not applicable | Completed | Shahid Beheshti University of Medical Sciences | 48 | 2018-07-15 | 2020-05-13 |
| Treatment of Aphtous Ulcers With Photodynamic Therapy Photodynamic therapy (indocyanine green+laser) - Oral Ulcer, Aphthous Recurrent Ulcers | Not applicable | Completed | Yuzuncu Yil University | 30 | 2018-03-05 | 2024-04-23 |
| Safety, Galenic Acceptability and Efficacy of GV-328 Lozenges in Children With Oral Aphthosis GV-328 - Aphthous Stomatitis | Not applicable | Completed | Universitat Internacional de Catalunya | 33 | 2017-11-01 | 2021-02-01 |
| The Salivary and Faecal Microbiome of Recurrent Aphthous Stomatitis Patients Before and After Treatment With Probiotics Probiotic lozenge - Recurrent Aphthous Ulcers | Not applicable | Completed | University of Copenhagen | 20 | 2016-03-14 | 2022-11-16 |
| Treatment of Recurrent Aphthous Stomatitis With Er,Cr:YSGG Laser Irradiation Er,Cr:YSGG Laser - Stomatitis, Aphthous | Not applicable | Completed | Near East University, Turkey | 40 | 2015-01-01 | 2016-10-05 |
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Oral Ulcer (5) · Pain (3) · Burning Mouth Syndrome (2) · Patient Compliance (2) · Ulcer (2) · Candidiasis, Oral (1) · Hereditary Autoinflammatory Diseases (1) · Herpesviridae Infections (1) · Lichen Planus (1) · Lichen Planus, Oral (1) · Mouth Diseases (1) · Oral Manifestations (1) · Pharyngitis (1) · Recurrence (1)
Stomatognathic Diseases (26) · Mouth Diseases (25) · Stomatitis (25) · Pathological Conditions, Signs and Symptoms (7) · Signs and Symptoms (4) · Neurologic Manifestations (3) · Pathologic Processes (3) · Skin Diseases (3) · Skin and Connective Tissue Diseases (3) · Behavior (2) · Health Behavior (2) · Infections (2) · Lichenoid Eruptions (2) · Patient Acceptance of Health Care (2) · Skin Diseases, Papulosquamous (2)
Vitamin B 12 (2) · Biopsy (1) · Colchicine (1) · Gels (1) · Hyaluronic Acid (1) · Hypericum extract LI 160 (1) · Low-Level Light Therapy (1) · Occlusal Splints (1) · Pentoxifylline (1) · Photochemotherapy (1) · Saline Solution (1) · Sodium Chloride (1) · Sodium Dodecyl Sulfate (1) · Thalidomide (1) · Triamcinolone (1)
Ain Shams University (1) · Ayat Gamal-AbdelNaser (1) · Batman University (1) · British University In Egypt (1) · Devintec Sagl (1) · EMS (1) · Federal University of Rio Grande do Sul (1) · G. d'Annunzio University (1) · Manchester University NHS Foundation Trust (1) · Meir Medical Center (1) · Nada Sherif (1) · National Institute of Dental and Craniofacial Research (NIDCR) (1) · National Institute of Nuclear Research - Mexico (1) · Near East University, Turkey (1) · ProofPilot (1)
Egypt (3) · Israel (2) · Italy (2) · Spain (2) · Turkey (Türkiye) (2) · United States (2) · Brazil (1) · China (1) · Denmark (1) · Iran (1) · Japan (1) · Mexico (1) · United Kingdom (1)
Ahmed Elsayed Hamed Amr, Lecturer (1) · Cennet N Eroglu, DDS,PhD (1) · Eric Bennett, Assoc Prof (1) · Ilia Volkov, MD (1) · Jeong-Seung Kwon (1) · Kathrine Bukkehave, Scholarstip (1) · Manoela Martins, PhD (1) · Martin H Thornhill, MBBS, BDS (1) · Matthew M Amsden (1) · Nasma Pulikkalakath (1) · Olfat Gameel Shaker, Professor (1) · Prof. Antonio Scarano Antonio Scarano, MD DDS (1)