52 completed, 9 terminated, 6 active not recruiting, 5 withdrawn. 37 Phase 1, 27 Phase 2, 7 Not applicable, 2 Early Phase 1, 2 Phase 3.
Follow Stage III Pancreatic Cancer: new trials by email Literature Review of Stage III Pancreatic Cancer trials Research Report on Stage III Pancreatic Cancer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Malnutrition Screening and Dietary Intervention to Improve Nutrition Outcomes in Patients With Unresectable Pancreatic Cancer Best Practice, Dietary Intervention, Medical Chart Review - Stage III Pancreatic Cancer, Pancreatic Adenocarcinoma Non-resectable | Not applicable | Active not recruiting | Jonsson Comprehensive Cancer Center | 100 | 2023-01-17 | 2026-05-26 |
| Study of Covalent Menin Inhibitor BMF-219 in Adult Patients With KRAS Driven Non-Small Cell Lung Cancer, Pancreatic Cancer, and Colorectal Cancer BMF-219 - Non Small Cell Lung Cancer, Pancreatic Cancer | Phase 1 | Terminated | Biomea Fusion Inc. | 13 | 2023-01-12 | 2025-02-07 |
| A Pivotal Study of Safety and Effectiveness of NanoKnife IRE for Stage 3 Pancreatic Cancer Modified FOLFIRINOX Regimen, NanoKnife System - Stage III Pancreatic Cancer | Phase 3 | Active not recruiting | Angiodynamics, Inc. | 528 | 2021-02-23 | 2025-02-12 |
| A Registry Study of NanoKnife IRE for Stage 3 Pancreatic Cancer SOC, NanoKnife System - Stage III Pancreatic Cancer | Active not recruiting | Angiodynamics, Inc. | 532 | 2019-05-08 | 2025-02-12 | |
| Trametinib and Hydroxychloroquine in Treating Patients With Pancreatic Cancer Hydroxychloroquine, Trametinib - Metastatic Pancreatic Carcinoma, Stage II Pancreatic Cancer | Phase 1 | Terminated | University of Utah | 25 | 2019-01-30 | 2026-05-14 |
| Ceralasertib (AZD6738) Alone and in Combination With Olaparib or Durvalumab in Patients With Solid Tumors Ceralasertib, Olaparib, Durvalumab - Clear Cell Renal Cell Carcinoma, Locally Advanced Pancreatic Cancer | Phase 2 | Active not recruiting | Rahul Aggarwal | 83 | 2019-01-17 | 2026-04-23 |
| TAS102 in Combination With NAL-IRI in Advanced GI Cancers Nanoliposomal Irinotecan, Trifluridine and Tipiracil Hydrochloride - Colorectal Adenocarcinoma, Gastric Adenocarcinoma | Phase 1 / Phase 2 | Active not recruiting | Emory University | 64 | 2018-01-30 | 2025-01-07 |
| VX15/2503 and Immunotherapy in Resectable Pancreatic and Colorectal Cancer Anti-SEMA4D Monoclonal Antibody VX15/2503, Ipilimumab, Nivolumab - Colon Carcinoma Metastatic in the Liver, Colorectal Adenocarcinoma | Phase 1 | Completed | Emory University | 10 | 2017-12-15 | 2024-03-20 |
| Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With Cancer Best Practice, Laboratory Biomarker Analysis, Supportive Care - Acute Myeloid Leukemia, Brain Glioblastoma | Not applicable | Completed | Stanford University | 128 | 2017-08-08 | 2025-01-24 |
| Pembrolizumab and XL888 in Patients With Advanced Gastrointestinal Cancer XL888, Pembrolizumab - Colorectal Adenocarcinoma, Metastatic Pancreatic Adenocarcinoma | Phase 1 | Completed | Emory University | 47 | 2017-07-07 | 2026-05-22 |
| Palbociclib With Cisplatin or Carboplatin in Advanced Solid Tumors Carboplatin, Cisplatin, Palbociclib - Solid Neoplasm, Stage III Pancreatic Cancer | Phase 1 | Completed | Emory University | 71 | 2016-10-24 | 2023-10-10 |
| Ascorbic Acid and Combination Chemotherapy in Treating Patients With Locally Advanced or Recurrent Pancreatic Cancer That Cannot Be Removed by Surgery Oxaliplatin, Irinotecan Hydrochloride, Leucovorin Calcium - Pancreatic Adenocarcinoma, Recurrent Pancreatic Carcinoma | Early Phase 1 | Completed | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University | 8 | 2016-10-18 | 2025-04-30 |
| BATS With in Combination With Low Dose IL-1 and GM-CSF for Advanced Pancreatic Cancer Aldesleukin, Antibody Therapy, Fluorouracil - Metastatic Pancreatic Adenocarcinoma, Recurrent Pancreatic Carcinoma | Phase 1 / Phase 2 | Completed | Barbara Ann Karmanos Cancer Institute | 2 | 2015-12-01 | 2023-05-15 |
| Recombinant EphB4-HSA Fusion Protein With Standard Chemotherapy Regimens in Treating Patients With Advanced or Metastatic Solid Tumors Cisplatin, Docetaxel, Gemcitabine Hydrochloride - Head and Neck Squamous Cell Carcinoma, Metastatic Pancreatic Adenocarcinoma | Phase 1 | Active not recruiting | University of Southern California | 61 | 2015-09-03 | 2026-04-29 |
| Preoperative Folfirinox for Resectable Pancreatic Adenocarcinoma - A Phase II Study Irinotecan Hydrochloride, Oxaliplatin, Leucovorin Calcium - Pancreatic Adenocarcinoma, Poorly Differentiated Malignant Neoplasm | Phase 2 | Terminated | Case Comprehensive Cancer Center | 1 | 2015-09-01 | 2018-07-13 |
| Electronic Monitoring Device of Patient-Reported Outcomes and Function in Improving Patient-Centered Care in Patients With Gastrointestinal Cancer Undergoing Surgery Computer-Assisted Intervention, Vivofit watch, Quality-of-Life Assessment - Stage I Adult Liver Cancer, Stage I Colorectal Cancer | Not applicable | Completed | City of Hope Medical Center | 22 | 2015-07-22 | 2021-01-07 |
| Dovitinib Lactate, Gemcitabine Hydrochloride, and Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced Solid Tumors or Pancreatic Cancer dovitinib lactate, gemcitabine hydrochloride, paclitaxel albumin-stabilized nanoparticle formulation - Duct Cell Adenocarcinoma of the Pancreas, Recurrent Pancreatic Cancer | Phase 1 | Withdrawn | Roswell Park Cancer Institute | 2015-03-01 | 2015-01-09 | |
| Neoadjuvant Chemotherapy Followed by Radiation Therapy and Gemcitabine/Sorafenib/Vorinostat in Pancreatic Cancer Gemcitabine, Sorafenib, Vorinostat - Pancreatic Adenocarcinoma, Stage IA Pancreatic Cancer | Phase 1 | Completed | Virginia Commonwealth University | 23 | 2015-01-29 | 2022-09-19 |
| Ceritinib and Combination Chemotherapy in Treating Patients With Advanced Solid Tumors or Locally Advanced or Metastatic Pancreatic Cancer Ceritinib, Cisplatin, Gemcitabine Hydrochloride - Advanced Malignant Solid Neoplasm, ALK Positive | Phase 1 | Completed | Roswell Park Cancer Institute | 38 | 2015-01-08 | 2022-07-25 |
| Palliative Care in Improving Quality of Life and Symptoms in Patients With Stage III-IV Pancreatic or Ovarian Cancer palliative care, educational intervention, quality-of-life assessment - Recurrent Ovarian Epithelial Cancer, Recurrent Ovarian Germ Cell Tumor | Not applicable | Withdrawn | City of Hope Medical Center | 2014-12-01 | 2014-12-23 |
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Pancreatic Neoplasms (73) · Colonic Neoplasms (12) · Rectal Neoplasms (12) · Carcinoma, Non-Small-Cell Lung (11) · Stomach Neoplasms (10) · Carcinoma, Renal Cell (7) · Colorectal Neoplasms (7) · Gallbladder Neoplasms (7) · Breast Neoplasms (6) · Urinary Bladder Neoplasms (6) · Carcinoma, Hepatocellular (5) · Carcinoma, Ovarian Epithelial (5) · Bile Duct Neoplasms (4) · Breast Neoplasms, Male (4) · Neoplasms (4)
Digestive System Diseases (73) · Digestive System Neoplasms (73) · Endocrine Gland Neoplasms (73) · Endocrine System Diseases (73) · Neoplasms by Site (73) · Pancreatic Diseases (73) · Neoplasms (69) · Gastrointestinal Diseases (20) · Neoplasms by Histologic Type (20) · Neoplasms, Glandular and Epithelial (19) · Carcinoma (18) · Colonic Diseases (18) · Intestinal Diseases (18) · Intestinal Neoplasms (18) · Rectal Diseases (18)
Gemcitabine (34) · Fluorouracil (15) · Leucovorin (10) · Irinotecan (9) · Oxaliplatin (9) · Taxes (8) · Bevacizumab (7) · Radiation (7) · Albumin-Bound Paclitaxel (6) · Capecitabine (6) · Erlotinib Hydrochloride (6) · Radiotherapy (6) · 130-nm albumin-bound paclitaxel (5) · Cisplatin (5) · dehydroftorafur (5)
National Cancer Institute (NCI) (27) · City of Hope Medical Center (5) · Emory University (4) · Roswell Park Cancer Institute (4) · University of Nebraska (3) · Wake Forest University Health Sciences (3) · Angiodynamics, Inc. (2) · Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University (2) · University of Chicago (2) · Albert Einstein College of Medicine (1) · Alliance for Clinical Trials in Oncology (1) · Barbara Ann Karmanos Cancer Institute (1) · Biomea Fusion Inc. (1) · Case Comprehensive Cancer Center (1) · Edward Kim (1)
United States (69) · Canada (3) · South Korea (1)
Hedy Kindler (5) · Virginia Sun (3) · Chi Lin (2) · Renuka Iyer (2) · Wen Wee Ma (2) · Alain Mita (1) · Andreas Kaubisch (1) · Andrew Ko (1) · Andrew Poklepovic, MD (1) · Anthony El-Khoueiry (1) · Anthony Shields (1) · Antonius Miller (1) · Arthur Blackstock (1) · Ben Chue, MD (1) · Betty Ferrell (1)
PMID 34233640, PMID 14520092, PMID 19636002, PMID 19738452, PMID 24987057, PMID 27275632, PMID 27701653, PMID 30222972, PMID 30825970, PMID 32504550, PMID 32939319, PMID 34028627, PMID 34616010, PMID 34749008, PMID 35771552, PMID 36221952, PMID 39863139, PMID 40973049, PMID 41686845
P30CA036727 (3), P30CA138292 (3), U10CA021661 (3), U10CA031946 (3), N01CM62201 (2), N01CM62203 (2), P30CA014599 (2), P30CA016056 (2), P30CA033572 (2), U01CA069856 (2), U01CA099118 (2), U01CA132123 (2), N01CM00070 (1), N01CM17003 (1), N01CM17102 (1)