13 completed, 6 not yet recruiting, 6 recruiting, 3 active not recruiting. 19 Not applicable, 6 Phase 2, 4 Phase 1, 3 Phase 3, 1 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| AngioVac Aspiration Therapy Registry Retrospective analysis of assigned treatment - Intracardiac Thrombus, Intracardiac Mass | Not yet recruiting | Charite University, Berlin, Germany | 1000 | 2026-10-01 | 2026-10-20 | |
| Irreversible Electroporation (IRE) for the Treatment of Lower Urinary Tract Symptoms (LUTS) in Men With Benign Prostatic Hyperplasia (BPH) Irreversible Electroporation - Lower Urinary Tract Symptoms (LUTS) in Men With Benign Prostatic Hyperplasia (BPH) | Not applicable | Not yet recruiting | Angiodynamics, Inc. | 40 | 2026-09-01 | 2026-06-11 |
| Auryon Atherectomy System With Standard Balloon Angioplasty Versus Standard Balloon Angioplasty Alone in Europe Auryon Atherectomy System, Balloon Angioplasty - Peripheral Arterial Disease | Not applicable | Not yet recruiting | Angiodynamics, Inc. | 50 | 2026-05-01 | 2026-03-16 |
| Comparing Two Different Boost Approaches in Radiation Therapy for People With Prostate Cancer NanoKnife System, Stereotactic Body Radiation Therapy - Prostate Cancer | Phase 3 | Recruiting | Memorial Sloan Kettering Cancer Center | 224 | 2026-04-16 | 2026-09-18 |
| Percutaneous AngioVac Vegetation Extraction (PAVE) to Remove Right Heart Vegetations in Patients With Infective Endocarditis AngioVac System - Infective Endocarditis (IE) | Not applicable | Not yet recruiting | Angiodynamics, Inc. | 30 | 2026-04-01 | 2026-04-22 |
| Acute Pulmonary Embolism Treatment With the AlphaVac Multipurpose Mechanical Aspiration System and the AlphaReturn Blood Management System: Evaluation of Safety and Effectiveness AlphaReturn Blood Management System - Pulmonary Embolism Acute | Not applicable | Recruiting | Angiodynamics, Inc. | 39 | 2026-03-30 | 2026-05-11 |
| International Study on Treatment of Liver (HCC) Patients With IRE Irreversible Electroporation - Hepatocellular Carcinoma (HCC), Liver Ablation | Not applicable | Not yet recruiting | Angiodynamics, Inc. | 50 | 2026-02-01 | 2025-10-10 |
| International Study on Treatment of Patients With Metastatic Colorectal Liver Lesions Patients With IRE Irreversible Electroporation - Colorectal Adenocarcinoma Metastatic in the Liver, Liver Ablation | Not applicable | Not yet recruiting | Angiodynamics, Inc. | 50 | 2026-02-01 | 2025-10-10 |
| Evaluating the Efficacy, Safety and Long Term Functional Outcomes of Percutaneous Mechanical Aspiration Thrombectomy for Treatment of Acute Pulmonary Embolism Using the AlphaVac Multipurpose Mechanical Aspiration (MMA) F1885 System AlphaVac Multipurpose Mechanical Aspiration (MMA) F1885 System - Acute Pulmonary Embolism (PE), Pulmonary Embolism | Not applicable | Recruiting | Angiodynamics, Inc. | 256 | 2025-06-15 | 2025-09-26 |
| Auryon Atherectomy System With Standard Balloon Angioplasty Versus Standard Balloon Angioplasty Alone Auryon Atherectomy System, Balloon Angioplasty - Peripheral Arterial Diseases | Phase 4 | Recruiting | Angiodynamics, Inc. | 224 | 2025-04-21 | 2026-01-08 |
| COLDFIRE-III Trial: Efficacy of Irreversible Electroporation and Stereotactic Body Radiotherapy for Perivascular and Peribiliary Colorectal Liver Metastases Irreversible electroporation, Stereotactic body radiotherapy - Colorectal Cancer, Liver Metastases | Phase 2 / Phase 3 | Recruiting | Amsterdam UMC, location VUmc | 78 | 2024-08-20 | 2024-08-23 |
| Dose Finding, Efficacy and Immunological Response of IP-001 Following MWA or IRE for CRLM IP-001 - Colorectal Cancer, Liver Metastases | Phase 1 / Phase 2 | Recruiting | M.R. Meijerink | 120 | 2024-07-10 | 2025-07-03 |
| Irreversible Electroporation & Pembro Immunotherapy in Locally Advanced Pancreatic Cancer Pembrolizumab, Irreversible Electroporation - Pancreatic Cancer, Locally Advanced Pancreatic Cancer | Phase 1 | Completed | H. Lee Moffitt Cancer Center and Research Institute | 2 | 2024-04-10 | 2026-02-09 |
| BORIS - aBlação pOR mIcro-ondaS [Microwave Ablation] Image guided percutaneous microwave ablation - Sarcoma | Not applicable | Unknown | Instituto do Cancer do Estado de São Paulo | 60 | 2023-06-01 | 2023-08-03 |
| Evaluating the Safety and Efficacy of the AlphaVac Multipurpose Mechanical Aspiration (MMA) F1885 PE for Treatment of Acute Pulmonary Embolism AlphaVac Multipurpose Mechanical Aspiration (MMA) F1885 PE - Pulmonary Embolism, Acute Pulmonary Embolism | Not applicable | Completed | Angiodynamics, Inc. | 122 | 2022-10-19 | 2024-07-19 |
| Pivotal Study of the NanoKnife System for the Ablation of Prostate Tissue Irreversible Electroporation - Prostate Cancer | Not applicable | Completed | Angiodynamics, Inc. | 121 | 2022-03-29 | 2026-06-02 |
| Prospective, Multi-center, Single-arm Study of the Auryon Laser System for Treatment of Below-the-Knee (BTK) Arteries Auryon Laser System - Peripheral Arterial Disease | Not applicable | Completed | Midwest Cardiovascular Research Foundation | 60 | 2022-03-17 | 2024-11-21 |
| Study of NanoKnife for Ablation of Prostate Cancer in Intermediate Risk Patients NanoKnife Procedure - Prostate Cancer | Not applicable | Unknown | Angiodynamics, Inc. | 6 | 2021-05-13 | 2023-02-01 |
| A Pivotal Study of Safety and Effectiveness of NanoKnife IRE for Stage 3 Pancreatic Cancer Modified FOLFIRINOX Regimen, NanoKnife System - Stage III Pancreatic Cancer | Phase 3 | Active not recruiting | Angiodynamics, Inc. | 528 | 2021-02-23 | 2025-02-12 |
| Post-Market Registry of AURYON Atherectomy Device in Subjects Affected With Infrainguinal Peripheral Artery Disease AURYON Atherectomy System - Infrainguinal Peripheral Artery Disease, Peripheral Arterial Disease | Completed | Angiodynamics, Inc. | 102 | 2020-08-04 | 2026-05-18 |
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Pancreatic Neoplasms (4) · Peripheral Arterial Disease (4) · Prostatic Neoplasms (4) · Carcinoma, Hepatocellular (3) · Pulmonary Embolism (3) · Breast Neoplasms (2) · Carcinoma, Pancreatic Ductal (2) · Colorectal Neoplasms (2) · Endocarditis (2) · Renal Insufficiency, Chronic (2) · Acute Kidney Injury (1) · Arterial Occlusive Diseases (1) · Bites and Stings (1) · Carcinoma, Non-Small-Cell Lung (1) · Chronic Limb-Threatening Ischemia (1)
Electroporation (8) · Angioplasty, Balloon (2) · Drug Delivery Systems (2) · Radiosurgery (2) · N-dihydrogalactochitosan (1) · Radiofrequency Ablation (1) · Thrombectomy (1) · pembrolizumab (1)
United States (20) · Netherlands (4) · Germany (3) · Italy (3) · United Kingdom (3) · Canada (2) · Australia (1) · Brazil (1) · France (1) · Poland (1) · Spain (1) · Switzerland (1)
Ajith Siriwardena, MD FRCS (2) · Martijn R. Meijerink, Prof. (2) · Riccardo Lencioni, MD (2) · Andrew Sharp (1) · Arvin George, MD (1) · Christoph Starck, Prof. Dr. med. (1) · Claudio Bassi, M.D. (1) · Daniela Ochoa, MD (1) · David Gillespie, MD (1) · David Hahn, MD (1) · Edward Lee, MD, PhD (1) · Erik Klok (1) · Himanshu Nagar, MD (1) · Jonathan Coleman, MD (1) · Jordi Bruix, MD (1)
PMID 34233640, PMID 18565793, PMID 22422482, PMID 22911363, PMID 25354827, PMID 26296371, PMID 28209559, PMID 32205128, PMID 38566525
2023 (1)