202 completed, 43 terminated, 19 unknown, 10 withdrawn. 131 Phase 2, 97 Phase 1, 33 Not applicable, 20 Phase 3, 5 Early Phase 1.
Follow this condition Literature Review of Breast Neoplasms, Male trials Research Report on Breast Neoplasms, Male
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Male breAsT cAncer preDisposition Factor: Creation of a Control Cohort 2 Questionnaire completion, Genetic analysis (WES) - Male Breast Cancer | Not applicable | Not yet recruiting | Institut Claudius Regaud | 120 | 2026-10-15 | 2026-08-19 |
| A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence Elacestrant, Anastrozole, Letrozole - Breast Cancer | Phase 3 | Recruiting | Stemline Therapeutics, Inc. | 4220 | 2024-09-27 | 2026-09-15 |
| MALE Mamm Organoids Breast Neoplasms, Male | Recruiting | Regina Elena Cancer Institute | 7 | 2024-04-19 | 2025-01-22 | |
| Phase IIIb Study of Ribociclib + ET in Early Breast Cancer Ribociclib, Letrozole, Ansastrozole - Early Breast Cancer | Phase 3 | Recruiting | Novartis Pharmaceuticals | 1444 | 2024-02-28 | 2026-10-19 |
| Access to Genetic Testing in Underserved Patients With Cancer Best Practice, Educational Intervention, Electronic Health Record Review - Breast Carcinoma, Male Breast Carcinoma | Not applicable | Recruiting | University of Southern California | 800 | 2023-10-24 | 2026-03-18 |
| ETHAN - ET for Male BC Tamoxifen, Anastrozole, Degarelix - Male Breast Cancer, Hormone Receptor-positive Breast Cancer | Phase 2 | Recruiting | Jose Pablo Leone | 60 | 2023-10-11 | 2026-08-24 |
| Predicting clinicAL outcoMes During First-line CDK4/6 Inhibitors Plus Endocrine Therapy in Patients With Advanced Hormone REceptor-poSitive HER2-negative Breast Cancer: the Retrospective-prospective Multicenter Italian PALMARES-2 Study Palbociclib, Ribociclib, Abemaciclib - Breast Adenocarcinoma, Breast Cancer Stage IV | Recruiting | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | 3500 | 2023-05-01 | 2025-02-03 | |
| Testosterone & Tamoxifen Trial AndroGel - Male Breast Cancer | Not applicable | Terminated | University Medical Center Groningen | 5 | 2022-11-10 | 2024-08-09 |
| PET-CT Imaging Using FDG-labeled Human Erythrocytes in Breast Cancer Patient Fluoro-D-glucose-positron Emission Tomography, 2-deoxy-2-[18F]fluoro-D-glucose (FDG), Echocardiogram - Breast Cancer, Breast Cancer, Female | Early Phase 1 | Withdrawn | H. Lee Moffitt Cancer Center and Research Institute | 2020-12-01 | 2020-12-04 | |
| EORTC Quality of Life Measurement in Males With Breast Cancer structured Interview - Male Breast Cancer, Quality of Life | Completed | Helios University Hospital Wuppertal | 65 | 2019-11-01 | 2026-03-27 | |
| Immune Response and Potential Booster for Patients Who Have Received HER2-pulsed DC1 HER2 DC1 Vaccine - Breast Cancer, HER2-positive Breast Cancer | Phase 2 | Terminated | H. Lee Moffitt Cancer Center and Research Institute | 16 | 2019-01-10 | 2022-04-25 |
| The Genetic Education for Men Trial: Web-Based Education vs. Standard Care Web-based Counseling, Standard Care - Prostate Carcinoma, Breast Neoplasm | Not applicable | Completed | Georgetown University | 63 | 2018-10-01 | 2023-09-13 |
| Study on the Progress of Breast Cancer Cases in Males and the Assessment of Relapse Risk Breast Cancer, Male | Completed | Spanish Breast Cancer Research Group | 777 | 2018-09-14 | 2025-02-26 | |
| HER2 Directed Dendritic Cell Vaccine During Neoadjuvant Therapy of HER2+Breast Cancer Dendritic Cell Vaccine (DC1), Neoadjuvant Chemotherapy, Curative Surgery - Breast Cancer, Breast Cancer Female | Early Phase 1 | Completed | H. Lee Moffitt Cancer Center and Research Institute | 31 | 2018-06-06 | 2026-09-23 |
| A Study of PF-06873600 in People With Cancer PF-06873600, Endocrine Therapy 1, Endocrine Therapy 2 - HR+ HER2- Metastatic Breast Cancer, Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer, Triple Negative Breast Cancer, Male Breast Cancer | Phase 1 / Phase 2 | Terminated | Pfizer | 155 | 2018-03-07 | 2025-11-14 |
| Vaccine to Prevent Recurrence in Patients With HER-2 Positive Breast Cancer DC1 Vaccine, WOKVAC Vaccine - Breast Cancer Female, Breast Cancer, Male | Phase 2 | Active not recruiting | H. Lee Moffitt Cancer Center and Research Institute | 119 | 2018-02-19 | 2026-03-06 |
| ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma ONC201 - Triple Negative Breast Cancer, Endometrial Cancer | Phase 2 | Completed | National Cancer Institute (NCI) | 30 | 2018-01-17 | 2022-08-23 |
| Phase I-II Study of Interferon-gamma in Patients With HER-2 Positive Breast Cancer Interferon-gamma (IFN-γ), Paclitaxel, Trastuzumab - Breast Cancer, Breast Cancer, Male | Phase 1 / Phase 2 | Completed | H. Lee Moffitt Cancer Center and Research Institute | 51 | 2017-06-23 | 2023-04-19 |
| Pilot Study of Paclitaxel Plus Pembrolizumab in Metastatic HER2-Negative Breast Cancer Pembrolizumab, Paclitaxel - Breast - Female, Male Breast Cancer | Phase 2 | Completed | Wake Forest University Health Sciences | 40 | 2017-06-12 | 2023-08-04 |
| QUILT-3.013: Study of Ad5 [E1-, E2b-]-HER2/Neu Vaccine (ETBX-021) in Subjects With Unresectable Locally Advanced or Metastatic HER2-Expressing Breast Cancer ETBX-021 - Cancer | Phase 1 | Terminated | NantBioScience, Inc. | 3 | 2017-03-04 | 2025-01-13 |
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Breast Neoplasms (276) · Carcinoma, Non-Small-Cell Lung (40) · Colonic Neoplasms (37) · Rectal Neoplasms (30) · Carcinoma, Ovarian Epithelial (29) · Prostatic Neoplasms (29) · Pancreatic Neoplasms (25) · Carcinoma, Renal Cell (21) · Lung Neoplasms (20) · Ovarian Neoplasms (20) · Small Cell Lung Carcinoma (20) · Triple Negative Breast Neoplasms (19) · Brain Neoplasms (18) · Melanoma (18)
Neoplasms by Site (286) · Skin Diseases (286) · Skin and Connective Tissue Diseases (286) · Breast Diseases (285) · Neoplasms (271) · Neoplasms by Histologic Type (69) · Neoplasms, Glandular and Epithelial (59) · Carcinoma (58) · Urogenital Diseases (57) · Urogenital Neoplasms (56) · Genital Diseases (52) · Endocrine Gland Neoplasms (48) · Endocrine System Diseases (48) · Female Urogenital Diseases (45) · Female Urogenital Diseases and Pregnancy Complications (45)
Cyclophosphamide (31) · Trastuzumab (30) · Paclitaxel (28) · Docetaxel (22) · Doxorubicin (18) · Taxes (18) · Lapatinib (15) · Radiotherapy (15) · Capecitabine (14) · Bevacizumab (13) · Tamoxifen (12) · Carboplatin (11) · Filgrastim (9) · Immunohistochemistry (9) · Biopsy (8)
National Cancer Institute (NCI) (57) · Alliance for Clinical Trials in Oncology (17) · University of Washington (17) · Memorial Sloan Kettering Cancer Center (9) · Case Comprehensive Cancer Center (8) · City of Hope Medical Center (7) · H. Lee Moffitt Cancer Center and Research Institute (7) · Jonsson Comprehensive Cancer Center (6) · SWOG Cancer Research Network (6) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (5) · European Organisation for Research and Treatment of Cancer - EORTC (4) · National Institutes of Health Clinical Center (CC) (4) · Northwestern University (4) · Vanderbilt-Ingram Cancer Center (4) · Mayo Clinic (3)
United States (234) · Canada (15) · United Kingdom (12) · France (9) · Germany (6) · Switzerland (6) · Puerto Rico (5) · Italy (4) · Netherlands (4) · Belgium (3) · Spain (3) · Taiwan (3) · Argentina (2) · Australia (2) · Brazil (2)
Edith A. Perez, MD (7) · Hannah Linden (5) · Lupe Salazar (5) · Harold Burstein (3) · Jennifer Specht (3) · Teresa Ann Gilewski, MD (3) · Winston Tan, MD, FACP (3) · Antoinette R. Tan, MD (2) · Antonio C. Wolff, MD (2) · Catherine Van Poznak, MD (2) · Elizabeth C. Dees, MD (2) · George Somlo, MD (2) · Herbert K. Lyerly, MD (2) · Ingrid Mayer, MD (2) · Leisha A. Emens, MD, PhD (2)
PMID 24737128, PMID 12114401, PMID 12636887, PMID 12689742, PMID 15284258, PMID 15314059, PMID 15352988, PMID 15516261, PMID 15542159, PMID 15912493, PMID 16849763, PMID 17182834, PMID 17458693, PMID 17606971, PMID 17761229, PMID 18160686, PMID 18245546, PMID 18327587, PMID 18470481, PMID 18519811, PMID 18723148, PMID 18800990, PMID 18824714, PMID 19625343, PMID 19687332, PMID 19690306, PMID 19901014, PMID 20068553, PMID 20122025, PMID 20124182, PMID 20479410, PMID 20800381, PMID 20888137, PMID 21272338, PMID 21350820, PMID 21766209, PMID 21874312, PMID 21895539, PMID 21917515, PMID 22200869, PMID 22444716, PMID 22480131, PMID 22868240, PMID 22915657, PMID 23006802, PMID 23122784, PMID 23430121, PMID 23798616, PMID 24013510, PMID 24013936
P30CA015704 (8), P30CA043703 (8), P30CA006973 (6), P30CA072720 (6), N01CM62205 (5), P30CA015083 (5), P30CA033572 (5), N01CM62204 (4), N01CM62209 (4), P30CA068485 (4), U01CA062502 (4), U10CA021115 (4), U10CA032102 (4), U10CA180821 (4), N01CM17003 (3)