11 completed, 2 terminated, 1 withdrawn. 6 Not applicable, 4 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 6 |
| Phase 1 | 4 | Completed 3, Terminated 1 |
| Phase 2 | 3 | Completed 1, Terminated 1, Withdrawn 1 |
Follow Stage IIC Rectal Cancer: new trials by email Literature Review of Stage IIC Rectal Cancer trials Research Report on Stage IIC Rectal Cancer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With Cancer Best Practice, Laboratory Biomarker Analysis, Supportive Care - Acute Myeloid Leukemia, Brain Glioblastoma | Not applicable | Completed | Stanford University | 128 | 2017-08-08 | 2025-01-24 |
| Regorafenib in Reducing Recurrence in Patients With Non-metastatic Rectal Cancer Who Have Completed Curative-Intent Treatment Laboratory Biomarker Analysis, Regorafenib - Rectal Adenocarcinoma, Stage IIA Rectal Cancer | Phase 2 | Withdrawn | Roswell Park Cancer Institute | 2015-03-01 | 2016-10-12 | |
| Phase I Study of Neoadjuvant Radiotherapy With 5-Fluorouracil for Rectal Cancer intensity-modulated radiation therapy, fluorouracil, oxaliplatin - Mucinous Adenocarcinoma of the Rectum, Recurrent Rectal Cancer | Phase 1 | Completed | Virginia Commonwealth University | 14 | 2014-12-04 | 2021-07-20 |
| Programs to Support You During Chemotherapy (Pro-You) Yoga Skills Training (YST), questionnaire administration, fatigue and depressive symptom assessment and management - Depressive Symptoms, Fatigue | Not applicable | Completed | Vanderbilt-Ingram Cancer Center | 3 | 2014-08-01 | 2015-06-23 |
| Genetic Mutations in Blood and Tissue Samples in Predicting Response to Treatment in Patients With Locally Advanced Rectal Cancer Undergoing Chemoradiation cytology specimen collection procedure, laboratory biomarker analysis - Mucinous Adenocarcinoma of the Rectum, Recurrent Rectal Cancer | Completed | Fox Chase Cancer Center | 43 | 2014-07-01 | 2024-05-02 | |
| Family Caregiver Palliative Care Intervention in Supporting Caregivers of Patients With Stage II-IV Gastrointestinal, Gynecologic, Urologic and Lung Cancers educational intervention, telephone-based intervention, quality-of-life assessment - Healthy Subject, Localized Transitional Cell Cancer of the Renal Pelvis and Ureter | Not applicable | Completed | City of Hope Medical Center | 200 | 2013-10-29 | 2026-10-01 |
| Bevacizumab, Fluorouracil, Leucovorin Calcium, and Oxaliplatin Before Surgery in Treating Patients With Stage II-III Rectal Cancer bevacizumab, oxaliplatin, leucovorin calcium - Mucinous Adenocarcinoma of the Rectum, Signet Ring Adenocarcinoma of the Rectum | Phase 2 | Terminated | University of Southern California | 17 | 2013-08-02 | 2026-07-01 |
| PET-MRI in Diagnosing Patients With Colon or Rectal Cancer positron emission tomography, computed tomography, magnetic resonance imaging - Recurrent Colon Cancer, Recurrent Rectal Cancer | Not applicable | Completed | Case Comprehensive Cancer Center | 15 | 2013-04-01 | 2021-05-18 |
| Adherence to Survivorship Care Guidelines in Health Care Providers for Non-Small Cell Lung Cancer and Colorectal Cancer Survivor Care educational intervention, medical chart review - Adenocarcinoma of the Lung, Mucinous Adenocarcinoma of the Colon | Not applicable | Completed | Fox Chase Cancer Center | 1440 | 2013-01-01 | 2017-04-06 |
| Survivorship Care Planning in Patients With Colorectal or Non-Small Cell Lung Cancer educational intervention, questionnaire administration, quality-of-life assessment - Stage I Colon Cancer, Stage I Rectal Cancer | Not applicable | Completed | City of Hope Medical Center | 30 | 2013-01-01 | 2013-12-18 |
| Trametinib, Fluorouracil, and Radiation Therapy Before Surgery in Treating Patients With Stage II-III Rectal Cancer trametinib, fluorouracil, radiation therapy - Recurrent Rectal Cancer, Stage IIA Rectal Cancer | Phase 1 | Completed | Ohio State University Comprehensive Cancer Center | 19 | 2012-11-26 | 2023-09-18 |
| Paricalcitol, Fluorouracil, and Radiation Therapy in Treating Patients With Rectal Cancer That Can Be Removed in Surgery paricalcitol, radiation therapy, laboratory biomarker analysis - Mucinous Adenocarcinoma of the Rectum, Stage IIA Rectal Cancer | Phase 1 | Terminated | Wake Forest University Health Sciences | 2 | 2010-08-01 | 2018-07-02 |
| Erlotinib Hydrochloride in Treating Patients With Stage I-III Colorectal Cancer or Adenoma erlotinib hydrochloride, placebo, laboratory biomarker analysis - Adenomatous Polyp, Recurrent Colon Cancer | Phase 2 | Completed | National Cancer Institute (NCI) | 45 | 2008-07-01 | 2015-01-06 |
| Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With Locally Advanced Rectal Cancer fluorouracil, oxaliplatin, radiation therapy - Adenocarcinoma of the Rectum, Mucinous Adenocarcinoma of the Rectum | Phase 1 | Completed | National Cancer Institute (NCI) | 20 | 1999-05-01 | 2013-01-10 |
Rectal Neoplasms (14) · Colonic Neoplasms (7) · Carcinoma, Non-Small-Cell Lung (3) · Carcinoma, Renal Cell (2) · Pancreatic Neoplasms (2) · Stomach Neoplasms (2) · Urinary Bladder Neoplasms (2) · Adenocarcinoma of Lung (1) · Adenomatous Polyps (1) · Bone Neoplasms (1) · Breast Neoplasms (1) · Carcinoma, Ovarian Epithelial (1) · Colorectal Neoplasms (1) · Depression (1) · Disease Progression (1)
Digestive System Diseases (14) · Digestive System Neoplasms (14) · Gastrointestinal Diseases (14) · Gastrointestinal Neoplasms (14) · Intestinal Diseases (14) · Intestinal Neoplasms (14) · Neoplasms (14) · Neoplasms by Site (14) · Rectal Diseases (14) · Colorectal Neoplasms (13) · Colonic Diseases (7) · Lung Diseases (4) · Neoplasms by Histologic Type (4) · Neoplasms, Glandular and Epithelial (4) · Respiratory Tract Diseases (4)
Fluorouracil (5) · Early Intervention, Educational (3) · Leucovorin (3) · Methods (3) · Oxaliplatin (3) · Radiation (3) · Radiotherapy (3) · 2-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole (1) · Bevacizumab (1) · Erlotinib Hydrochloride (1) · Fluorodeoxyglucose F18 (1) · Magnetic Resonance Spectroscopy (1) · Palliative Care (1) · Practice Guidelines as Topic (1) · Radiotherapy, Intensity-Modulated (1)
City of Hope Medical Center (2) · Fox Chase Cancer Center (2) · National Cancer Institute (NCI) (2) · Case Comprehensive Cancer Center (1) · Ohio State University Comprehensive Cancer Center (1) · Roswell Park Cancer Institute (1) · Stanford University (1) · University of Southern California (1) · Vanderbilt-Ingram Cancer Center (1) · Virginia Commonwealth University (1) · Wake Forest University Health Sciences (1)
United States (14)
Afsaneh Barzi (1) · Betty Ferrell (1) · Crystal Denlinger, MD (1) · Daniel Haller (1) · Emma C Fields, MD (1) · George Yacoub, MD (1) · Joshua Meyer (1) · Manali Patel (1) · Patrick Boland (1) · Raj Paspulati, MD (1) · Sameek Roychowdhury, MD (1) · Stephanie Sohl (1) · Timothy Morgan (1) · Virginia Sun (1)
PMID 32649004, PMID 34749008, PMID 35771552
N01CN35160 (1), P30CA006927 (1), P30CA014089 (1), P30CA016056 (1), P30CA016059 (1), P30CA068485 (1), U10CA021115 (1)