15 completed, 10 unknown, 4 terminated, 1 not yet recruiting. 33 Phase 3, 7 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 33 | Completed 15, Unknown 10, Terminated 4, Not yet recruiting 1, Recruiting 1, Suspended 1, Withdrawn 1 |
| Phase 2 | 7 | Completed 4, Unknown 2, Suspended 1 |
Follow Sprains and Strains: new trials by email Literature Review of Sprains and Strains trials Research Report on Sprains and Strains
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Topical Diclofenac vs.Oral Ibuprofen for MSK Pain in Children Voltaren Topical Gel, Ibuprofen Oral Suspension 100 mg/5mL, ORA-Blend Oral Suspension - Musculoskeletal Injury, Pediatrics | Phase 3 | Recruiting | University of Calgary | 60 | 2026-04-02 | 2026-04-13 |
| Hyaluronic Acid Injection in Idiopathic Carpal Tunnel Syndrome; is it Effective as Local Corticosteroids Low Molecular Weight Hyaluronic Acid, corticosteroid - Carpal Tunnel Syndrome (CTS) | Phase 3 | Not yet recruiting | Minia University Hospital | 60 | 2026-02-01 | 2026-03-17 |
| Efficacy And Tolerability Of Alpha Lipoic Acid And Vitamin B Preparation In Carpal Tunnel Syndrome Bionerv, Placebo - Carpal Tunnel Syndrome (CTS) | Phase 2 / Phase 3 | Completed | Universiti Putra Malaysia | 70 | 2023-12-01 | 2025-04-23 |
| Ultrasound-guided Dextrose Injection Versus Dextrose With Methylprednisolone in Carpal Tunnel Syndrome 5% dextrose injection, 5% dextrose injections with methylprednisolone acetate 40 mg/ml - Carpal Tunnel Syndrome | Phase 3 | Unknown | General and Veteran Hospital Croatian Pride Knin | 70 | 2023-09-13 | 2023-09-21 |
| Hyaluronic Acid in Overuse Knee Pain KNEE JOINT INFILTRATION WITH HYALURONIC ACID WITH SORBITOL SYNOLIS VA - Overuse Injury, Body Mass Index in Athletes | Phase 2 / Phase 3 | Completed | Hospital Regional Tlalnepantla | 64 | 2023-02-01 | 2025-07-22 |
| Efficacy and Safety Study of Ibuprofen Gel Compared to Placebo in the Treatment of Acute Musculoskeletal Pain Ibuprofen gel, Placebo - Musculoskeletal Pain, Acute Pain | Phase 3 | Unknown | Brainfarma Industria Química e Farmacêutica S/A | 300 | 2022-08-01 | 2022-03-21 |
| The SToICAL Study - The Soft Tissue Injection of Corticosteroid And Local Anaesthetic Study 1ml of triamcinolone (40mg/1ml) - Carpal Tunnel Syndrome, De Quervains Tenosynovitis | Phase 3 | Terminated | University Hospital Plymouth NHS Trust | 25 | 2020-02-26 | 2026-09-17 |
| Ultrasound-guided PRP Versus Steroid Injections in Management of Carpal Tunnel Syndrome platlet rich plasma (PRP), Triamcinolone Acetonide, Saline - Carpal Tunnel Syndrome | Phase 2 / Phase 3 | Unknown | Tanta University | 90 | 2020-02-01 | 2020-06-16 |
| Platelet Rich Plasma in Carpal Tunnel Syndrome Local platelet rich plasma (PRP) injection-T-Lab PRP kit, Local steroid injection-Diprospan ®, Schering Plough - Carpal Tunnel Syndrome | Phase 3 | Unknown | Baskent University | 84 | 2018-07-15 | 2019-06-28 |
| Efficacy of Lidocaine Patch in Acute Musculoskeletal Pain in the Emergency Department Ibuprofen, Lidocaine Patch 4% - Acute Musculoskeletal Disease, Sprains | Phase 3 | Completed | East Carolina University | 23 | 2018-06-23 | 2024-03-25 |
| Assessment of the Effectiveness of Ultrasound-guided Acupuncture in the Management of Carpal Tunnel Syndrome SHINCORT, XYLOCAINE, sham electroacupuncture - Carpal Tunnel Syndrome | Phase 2 / Phase 3 | Unknown | Taipei Medical University Hospital | 72 | 2016-08-01 | 2016-08-19 |
| Acetyl-l-carnitine to Enhance Nerve Regeneration in Carpal Tunnel Syndrome Acetyl-l-carnitine, placebo - Carpal Tunnel Syndrome, Compression Neuropathy | Phase 2 / Phase 3 | Completed | University of Alberta | 20 | 2015-09-01 | 2017-10-27 |
| Epidemiology of Incidents and Accidents in Sport. Influence of Moisture. eau minérale d'Aix-Les-Bains, tap water - Fractures, Sprain | Phase 3 | Unknown | Centre de Recherche Rhumatologique et Thermal | 50 | 2015-04-01 | 2015-02-10 |
| An Efficacy and Safety Study for the Treatment of Mild to Moderate Acute Pain Associated With Ankle Strain or Sprain. K-103-IP, Placebo - Acute Pain From Ankle Sprain or Strain | Phase 3 | Terminated | Kowa Research Institute, Inc. | 384 | 2014-04-01 | 2017-03-03 |
| Clinical Study Comparing the Efficacy of Transbuccal Paracetamol 125 mg Versus Paracetamol Injection 1g in Slow Infusion IV in Patients With Acute Pain paracetamol, Placebo - Acute Pain | Phase 3 | Completed | University Hospital, Clermont-Ferrand | 43 | 2012-05-01 | 2026-08-05 |
| Sonography-guided Steroid Injection for Carpal Tunnel Syndrome betamethasone - Carpal Tunnel Syndrome(CTS) | Phase 3 | Completed | Chang Gung Memorial Hospital | 39 | 2011-08-01 | 2015-10-15 |
| Study to Assess the Efficacy and Safety of Ibuprofen 50 mg/g Gel Compared to Profenid 25mg/g Gel Ibuprofen, Profenid - Muscular Atrophy, Sprains | Phase 3 | Unknown | Laboratório Teuto Brasileiro S/A | 144 | 2011-06-01 | 2011-06-15 |
| Sonographic Examination Cubital Tunnel Release Cubital tunnel release - Ulnar Nerve Compression, Cubital Tunnel | Phase 3 | Completed | Ente Ospedaliero Cantonale, Bellinzona | 60 | 2011-05-01 | 2016-04-15 |
| To Evaluate the Efficacy and Safety Aliviador Compared to Gelol in Patients With Contusions, Sprains, Trauma and Muscle Injury. Aliviador, Gelol - Contusions, Sprains | Phase 3 | Unknown | Laboratorio Brasileiro de Biologia | 120 | 2010-06-01 | 2010-04-16 |
| Preoperative Gabapentine for Carpal Tunnel Gabapentine, Sugar pill - Carpal Tunnel Syndrome | Phase 3 | Completed | Federal University of São Paulo | 40 | 2010-03-01 | 2019-03-05 |
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Carpal Tunnel Syndrome (15) · Pain (12) · Acute Pain (4) · Contusions (4) · Tendinopathy (4) · Myalgia (3) · Wounds and Injuries (3) · Ankle Injuries (2) · Cartilage Diseases (2) · Cubital Tunnel Syndrome (1) · Cumulative Trauma Disorders (1) · De Quervain Disease (1) · Emergencies (1) · Fractures, Bone (1)
Wounds and Injuries (30) · Nervous System Diseases (19) · Neuromuscular Diseases (19) · Neurologic Manifestations (17) · Pathological Conditions, Signs and Symptoms (17) · Signs and Symptoms (17) · Cumulative Trauma Disorders (16) · Mononeuropathies (16) · Nerve Compression Syndromes (16) · Peripheral Nervous System Diseases (16) · Median Neuropathy (15) · Musculoskeletal Diseases (8) · Muscular Diseases (7) · Pain (5)
Ibuprofen (3) · Ketoprofen (3) · Acetaminophen (2) · Gabapentin (2) · Methylprednisolone Acetate (2) · Sodium Chloride (2) · Triamcinolone Acetonide (2) · Acetylcarnitine (1) · Adrenal Cortex Hormones (1) · Anticonvulsants (1) · Betamethasone (1) · Electroacupuncture (1) · Glucose (1) · Hyaluronic Acid (1) · Hydrocodone (1)
Imprimis Pharmaceuticals, Inc. (2) · Alkemira SA (1) · Baskent University (1) · Brainfarma Industria Química e Farmacêutica S/A (1) · Centre de Recherche Rhumatologique et Thermal (1) · Cerimon Pharmaceuticals (1) · Chang Gung Memorial Hospital (1) · Chinese University of Hong Kong (1) · East Carolina University (1) · Endo USA Inc., a Keenova Therapeutics Company (1) · Ente Ospedaliero Cantonale, Bellinzona (1) · Excel-Tech Ltd. (1) · Federal University of São Paulo (1) · General and Veteran Hospital Croatian Pride Knin (1) · Hisamitsu Farmaceutica do Brasil Ltda (1)
United States (9) · Brazil (2) · Canada (2) · Egypt (2) · Croatia (1) · France (1) · Hong Kong (1) · Malaysia (1) · Mexico (1) · Sweden (1) · Switzerland (1) · Thailand (1) · Turkey (Türkiye) (1) · United Kingdom (1)
Abel Pereira Junior, investigator (1) · Abel Pereira, investigator (1) · Andrew CF Hui, FHKAM (1) · Beth Fisher, PhD, PT (1) · Charles Gozzard, MD (1) · Illana Katsnelson, MD (1) · Isam Atroshi, MD, PhD (1) · Jennifer Stahl, MD (1)
PMID 10411196, PMID 17113683, PMID 20409331, PMID 20958995, PMID 24026316, PMID 26000668, PMID 27079660, PMID 34583762, PMID 34677593, PMID 36794826, PMID 40325784, PMID 42814735, PMID 9771609