7 completed, 2 recruiting. 3 Phase 3, 3 Phase 4, 2 Not applicable, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 3 | Completed 3 |
| Phase 4 | 3 | Completed 2, Recruiting 1 |
| Not applicable | 2 | Completed 2 |
| Phase 2 | 2 | Completed 1, Recruiting 1 |
Follow Benign essential blepharospasm: new trials by email Literature Review of Benign essential blepharospasm trials Research Report on Benign essential blepharospasm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| DaxibotulinumtoxinA for Blepharospasm Botulinum Neurotoxin Type A - Blepharospasm of Both Eyelids, Blepharospasm of Left Eyelid | Phase 2 | Recruiting | University of Pennsylvania | 20 | 2026-09-24 | 2026-09-29 |
| Effects of DaxibotulinumtoxinA for Blepharospasm and Hemifacial Spasm DaxibotulinumtoxinA - Benign Essential Blepharospasm, Hemifacial Spasm | Phase 4 | Recruiting | Montefiore Medical Center | 40 | 2025-02-11 | 2026-04-23 |
| Effect of Non-psychoactive Cannabidiol as an Adjunct to Botulinum Toxin in Blepharospasm Cannabidiol Oral Solution [Epidiolex] - Blepharospasm, Blepharospasm, Benign Essential | Phase 2 / Phase 3 | Completed | Silkiss Eye Surgery | 12 | 2020-05-20 | 2021-11-02 |
| The Role of the Upper Colliculus in the Idiopathic Blepharospasm fMRI - Blepharospasm, Benign Essential | Not applicable | Completed | University Hospital, Grenoble | 13 | 2019-11-20 | 2022-09-16 |
| Clinical Study to Evaluate the Efficacy and Safety of Neuronox and Botox With Essential Blepharospasm Neuronox, Botox - Essential Blepharospasm | Phase 3 | Completed | Medy-Tox | 140 | 2016-05-25 | 2017-07-13 |
| The Objective of This Study is to Evaluate the Efficacy and Safety of Botulax® in Patients With Essential Blepharospasm. Botulinum toxin type A - Essential Blepharospasm | Phase 4 | Completed | Hugel | 249 | 2015-04-30 | 2018-08-22 |
| rTMS and Botulinum Toxin in Benign Essential Blepharospasm Magstim RapidStim2, Sham Magstim RapidStim2 - Benign Essential Blepharospasm | Not applicable | Completed | University of Florida | 12 | 2015-02-01 | 2023-09-15 |
| Efficacy and Safety Study of Meditoxin® to Treat Essential Blepharospasm Botulinum Toxin Type A - Essential Blepharospasm | Phase 4 | Completed | Medy-Tox | 110 | 2010-08-01 | 2012-04-25 |
| Therapeutic Confirmatory Clinical Trial to Evaluate the Safety and Efficacy of "Hugeltox Inj." in Essential Blepharospasm Hugeltox, Botulinum Toxin Type A(Botox®) - Essential Blepharospasm | Phase 3 | Completed | Hugel | 172 | 2008-04-01 | 2013-02-15 |
Blepharospasm (2) · Dystonia (1) · Hemifacial Spasm (1) · Parkinsonian Disorders (1)
Eye Diseases (2) · Eyelid Diseases (2) · Nervous System Diseases (2) · Neurologic Manifestations (2) · Pathological Conditions, Signs and Symptoms (2) · Signs and Symptoms (2) · Basal Ganglia Diseases (1) · Brain Diseases (1) · Central Nervous System Diseases (1) · Dyskinesias (1) · Mouth Diseases (1) · Movement Disorders (1) · Neuromuscular Manifestations (1) · Spasm (1) · Stomatognathic Diseases (1)
Botulinum Toxins, Type A (6) · Cannabidiol (1) · Injections (1)
Hugel (2) · Medy-Tox (2) · Montefiore Medical Center (1) · Silkiss Eye Surgery (1) · University Hospital, Grenoble (1) · University of Florida (1) · University of Pennsylvania (1)
United States (4) · South Korea (3) · France (1)
Anne Barmettler, MD (1) · Aparna Wagle-Shukla, MD (1) · Jaechan Kim, M.D., Ph.D. (1) · Sara Meoni, MD, PhD (1) · Yoon-Duck Kim, M.D., Ph.D. (1)
2023 (1)