4 completed, 1 active not recruiting, 1 unknown. 6 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 4, Active not recruiting 1, Unknown 1 |
| Phase 3 | 1 | Completed 1 |
Follow Sleep Apnea, Central: new trials by email Literature Review of Sleep Apnea, Central trials Research Report on Sleep Apnea, Central
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Efficacy Study of Sivopixant, Acetazolamide and SASS-001 in Sleep Apnea Sivopixant, Placebo, Acetazolamide - Sleep Apnea | Phase 2 | Active not recruiting | Shionogi | 60 | 2025-04-02 | 2026-05-06 |
| Managing Opioid Related Sleep Apnea With Acetazolamide Acetazolamide, Placebo - Sleep-Disordered Breathing, Obstructive Sleep Apnea | Phase 2 | Completed | University of California, San Diego | 39 | 2023-10-18 | 2026-03-10 |
| Apnea and Insomnia Relief Study Apnea and Insomnia Relief (AIR), Sleep Education (SE) - Sleep Apnea Syndromes, Insomnia Disorder | Phase 2 | Completed | VA Office of Research and Development | 36 | 2020-02-27 | 2026-03-12 |
| Assessment of Desogestrel in Ondine Syndrome desogestrel - Ondine Syndrome | Phase 2 / Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 6 | 2011-04-01 | 2013-11-14 |
| Chronic Evaluation of Respicardia Therapy remedē (TM) system - Sleep Disordered Breathing, Cheyne Stokes Respiration | Phase 2 | Completed | Respicardia, Inc. | 57 | 2010-05-01 | 2016-05-16 |
| Dynamic Carbon Dioxide (CO2) Administration for Sleep Apnoea Carbon dioxide - Sleep Apnea, Central | Phase 2 | Unknown | Imperial College London | 24 | 2010-02-01 | 2010-01-05 |
Sleep Apnea Syndromes (5) · Sleep Apnea, Obstructive (3) · Cheyne-Stokes Respiration (1) · Chronic Pain (1) · Heart Failure (1) · Sleep Initiation and Maintenance Disorders (1) · Stress Disorders, Post-Traumatic (1)
Apnea (6) · Dyssomnias (6) · Nervous System Diseases (6) · Respiration Disorders (6) · Respiratory Tract Diseases (6) · Sleep Disorders, Intrinsic (6) · Sleep Wake Disorders (6) · Pathological Conditions, Signs and Symptoms (2) · Signs and Symptoms (2) · Cardiovascular Diseases (1) · Heart Diseases (1) · Mental Disorders (1) · Neurologic Manifestations (1) · Pain (1) · Signs and Symptoms, Respiratory (1)
Acetazolamide (2) · Carbon Dioxide (1) · Desogestrel (1) · Drug Delivery Systems (1) · sivopixant (1)
Assistance Publique - Hôpitaux de Paris (1) · Imperial College London (1) · Respicardia, Inc. (1) · Shionogi (1) · University of California, San Diego (1) · VA Office of Research and Development (1)
United States (4) · Italy (2) · France (1) · Germany (1) · Poland (1) · United Kingdom (1)
Darrel P Francis, MD (1) · Jeremy Orr, MD (1) · Lizabeth A Goldstein, PhD (1) · Piotr Ponikowski, MD (1) · William T Abraham, MD (1)
PMID 21801857, PMID 25268234, PMID 25770408, PMID 30325462, PMID 38336689
K23HL151880 (1)