30 completed, 6 unknown, 4 terminated, 2 recruiting. 16 Phase 4, 8 Phase 2, 8 Phase 3, 7 Not applicable, 5 Phase 1.
Follow Desogestrel: new trials by email Literature Review of Desogestrel trials Research Report on Desogestrel
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| An Ethno-bridging Study of Pergoveris in Healthy Premenopausal Participants of Japanese or Caucasian Origin Desogestrel and ethinylestradiol fixed dose combination, Follitropin alfa/lutropin alfa - Fertility | Phase 1 | Completed | Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany | 24 | 2025-11-24 | 2026-03-18 |
| Effect of Elagolix in Symptomatic Endometrioma in Comparison to Combined Oral Contraceptive Pill. tab Elagolix 150mg, Combined oral contraceptive pill (ethinyl estradiol,30mcg+desogestrel,150mcg) tablet - Endometrioma | Not applicable | Completed | Mst.Sumyara Khatun | 60 | 2025-04-17 | 2026-08-13 |
| Effect of Dienogest in Symptomatic Endometrioma in Comparison to Combined Oral Contraceptive Pill. Tab.Dienogest 2 mg, Combined oral contraceptive pill (ethinyl estradiol,30mcg+desogestrel,150mcg) tablet - Endometrioma | Not applicable | Completed | Mst.Sumyara Khatun | 60 | 2025-04-17 | 2026-08-18 |
| PPOS (Progestin Primed Ovarian Stimulation) and Corifollitropin Alfa (CFA) Cross-over Study Elonva®, Puregon®, Orgalutran® - Ovarian Stimulation, Quality of Life | Phase 4 | Recruiting | University Hospital, Ghent | 60 | 2025-01-27 | 2025-12-26 |
| Oral Contraceptive Pill (OCP) Pharmacogenomics Desogestrel / Ethinyl Estradiol Pill - Contraception, Pharmacogenomic Drug Interaction | Phase 4 | Recruiting | Yale University | 700 | 2024-10-29 | 2026-07-16 |
| Desogestrel-containing COCP Pharmacokinetic Validation Study Desogestrel and Ethinyl Estradiol Tablets - Contraception | Phase 4 | Completed | University of Colorado, Denver | 22 | 2021-09-10 | 2025-05-30 |
| Desogestrel for the Preoperative Treatment of Endometrioma Compared With Placebo Desogestrel Oral Tablet - Endometrioma | Phase 2 / Phase 3 | Completed | Department of Medical Services Ministry of Public Health of Thailand | 20 | 2021-06-01 | 2022-10-31 |
| Desogestrel Versus GnRH Antagonist in IVF/ICSI Desogestrel 0.075 MG, Orgalutran - IVF, Infertility | Phase 4 | Unknown | Casa di Cura Privata Villa Mafalda | 165 | 2020-10-01 | 2021-01-28 |
| Bioavailability of Desogestrel 0.075 mg Tablets With Regards to Reference Product Desogestrel 0.075 MG - Bioequivalence | Phase 1 | Completed | Laboratorios Andromaco S.A. | 30 | 2020-01-11 | 2020-06-09 |
| Traditional Chinese Medicine, Western Medicine and Low-level Light Therapy（LLLT） for Primary Dysmenorrhea（PD） low level light therapy, DING KUN DAN, Simulated drug of DING KUN DAN - Primary Dysmenorrhea, Traditional Chinese Medicine | Phase 4 | Unknown | Peking Union Medical College Hospital | 480 | 2019-06-22 | 2019-06-25 |
| Abnormal Uterine Bleeding and Progestin-only Contraceptives Depot medroxy-progesterone acetate, Etonogestrel, Desogestrel 75 µg - Contraception | Completed | Assiut University | 390 | 2018-08-01 | 2020-12-17 | |
| Drug-drug Interaction Between Rifampicin and Progestins/Ethinylestradiol and Midazolam levonorgestrel/ Microlut, Norethindrone/ Noriday, Desogestrel/ Cerazette - Biological Availability | Phase 1 | Completed | Bayer | 68 | 2017-11-29 | 2020-04-15 |
| Optimisation of Follicular Recruitment in IVM Cycles blood sampling, transvaginal ultrasound scanning, oocyte retrieval for IVM - Infertility, Female, Polycystic Ovary Syndrome | Phase 3 | Completed | Universitair Ziekenhuis Brussel | 145 | 2017-11-01 | 2023-04-07 |
| Desogestrel (DSG) and Corifollitropin(FSH-CTP) Alfa for Ovarian Stimulation in Donors FSH-CTP + DESOGESTREL - Infertility | Phase 4 | Withdrawn | Fundacion Dexeus | 2016-05-01 | 2018-09-05 | |
| Desogestrel (DSG) and Corifolitropin (FSH-CTP) Alfa for Ovarian Stimulation in Donors Desogestrel (DSG) and Corifolitropin (FSH-CTP) Alfa - Controlled Ovaria Stimulation | Completed | Fundacion Dexeus | 40 | 2016-01-01 | 2017-11-28 | |
| Effects of Oral vs. Non-oral Contraceptives on the GH/IGF-1 Axis Combined Oral Contraceptive, Transdermal Contraceptive, Contraceptive Vaginal Ring - Bone; Disorder, Development and Growth | Phase 4 | Completed | Penn State University | 60 | 2015-01-01 | 2020-03-09 |
| Assessing the Impact of Contraceptives on Bone Health Using 41Ca Combined Oral Contraceptive (COC), Contraceptive Vaginal Ring (CVR) - Other Disorders of Bone Development and Growth | Phase 4 | Active not recruiting | Penn State University | 6 | 2015-01-01 | 2026-07-06 |
| Efficacy of Cyclic DSG Compared With Cyclic MPA for the Treatment of Anovulatory DUB Desogestrel, Medroxyprogesterone acetate - Dysfunctional Uterine Bleeding | Phase 3 | Unknown | Mahidol University | 160 | 2013-08-01 | 2018-08-22 |
| NuvaRing Versus Marvelon in the Coordination of In Vitro Fertilization Cycles Contraceptives, Oral, Contraceptive, Vaginal ring - Infertility | Phase 4 | Terminated | Clinique Ovo | 7 | 2012-07-01 | 2015-07-27 |
| Therapeutic Effect of Desogestrel on Ventilatory Control in Patients With Congenital Central Hypoventilation Syndrome Desogestrel - Congenital Central Hypoventilation Syndrome | Phase 2 | Terminated | Children's Hospital Los Angeles | 1 | 2012-02-01 | 2023-11-18 |
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Infertility (7) · Endometriosis (4) · Thrombosis (2) · Acne Vulgaris (1) · Amenorrhea (1) · Bone Diseases, Metabolic (1) · Congenital central hypoventilation syndrome (1) · Contraception Behavior (1) · Hemorrhage (1) · Infertility, Female (1) · Menstruation Disturbances (1) · Metrorrhagia (1) · Myofibroma (1) · Osteoporosis (1) · Patient Compliance (1)
Bayer (4) · Teva Branded Pharmaceutical Products R&D, Inc. (3) · Fundacion Dexeus (2) · Mahidol University (2) · Mst.Sumyara Khatun (2) · Organon and Co (2) · Penn State University (2) · University of Saskatchewan (2) · Assistance Publique - Hôpitaux de Paris (1) · Assiut University (1) · Casa di Cura Privata Villa Mafalda (1) · Children's Hospital Los Angeles (1) · Chulalongkorn University (1) · Clinique Ovo (1) · Department of Medical Services Ministry of Public Health of Thailand (1)
United States (11) · Thailand (6) · Italy (4) · Canada (3) · Germany (3) · Bangladesh (2) · Belgium (2) · Chile (2) · China (2) · Iran (2) · Spain (2) · United Kingdom (2) · Argentina (1) · Australia (1) · Colombia (1)
Mary Jane De Souza, PhD (2) · Aaron M Lazorwitz, MD, PhD (1) · Dan Apter, Docent (1) · Edith Weisberg, MB BS MM (1) · H. Coelingh Bennink, MD, PhD (1) · Iris Perez, MD (1) · Jacques Kadoch, MD (1) · Jeffrey T Jensen, MD., MPH (1) · Jirath Wichianpitaya, M.D. (1)
PMID 21801857, PMID 21816790, PMID 21880278, PMID 21954280, PMID 22252944, PMID 24903202, PMID 25074072, PMID 25268234, PMID 27328486, PMID 28297591, PMID 28525302, PMID 30301734, PMID 30476179, PMID 30639922, PMID 31603998, PMID 31654294, PMID 32612574, PMID 33650928, PMID 34826668, PMID 35028764, PMID 35102226, PMID 37331464, PMID 38336689, PMID 39615778, PMID 41065045
2009 (1), 2017 (1), 2023 (1), R01HD060827 (1), R01HD111436 (1)