10 completed, 6 unknown, 5 recruiting, 5 terminated. 16 Phase 2, 8 Not applicable, 4 Phase 1, 2 Phase 3, 1 Early Phase 1.
Follow Nose Neoplasms: new trials by email Literature Review of Nose Neoplasms trials Research Report on Nose Neoplasms
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer SX-682, DTX - Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma | Phase 1 / Phase 2 | Recruiting | National Cancer Institute (NCI) | 120 | 2026-11-11 | 2026-11-06 |
| Functional and Aesthetic Comparison of Surgical Nasal Reconstruction Versus Nasal Prosthesis (Epithesis) After Total or Subtotal Nasal Amputation SCHNOS score - Nose Cancer, Rhinectomy | Not yet recruiting | Hôpital NOVO | 20 | 2026-07-01 | 2026-07-01 | |
| Evaluation of Endoscopic Management of Sinonasal Tumors In Difficult Anatomical Locations endoscopic approch - Nasal Cavity and Paranasal Sinus Cancer | Not applicable | Not yet recruiting | Assiut University | 25 | 2026-04-01 | 2026-04-06 |
| Toripalimab With Chemotherapy for Sinus Cancer Toripalimab, Carboplatin, Docetaxel - Sinonasal Cancer, Paranasal Sinus Neoplasms | Phase 2 | Recruiting | Dana-Farber Cancer Institute | 20 | 2025-06-17 | 2026-08-31 |
| Somesthesia in Cancer Patients: Variability and Influence on Eating Experience Salivary test, Food tasting, Questionnaires - Digestive Cancers, Breast Cancer | Not yet recruiting | Hospices Civils de Lyon | 96 | 2025-03-13 | 2025-02-06 | |
| Defining the Clinical Potential of Mass Response As a Biomarker for Patient Tumor Sensitivity to Drugs Stage III Breast Cancer, Stage IV Breast Cancer | Withdrawn | Travera Inc | 2024-11-01 | 2024-11-25 | ||
| A Clinical Study on Oncolytic Virus Injection (R130 OV) for the Treatment of Relapsed/Refractory Head and Neck Cancer Recombinant oncolytic herpes simplex virus type 1 (R130) - Head and Neck Cancer, Esophageal Cancer | Early Phase 1 | Unknown | Shanghai Yunying Medical Technology | 9 | 2023-03-27 | 2023-04-26 |
| Utility of Indocyanine Green Fluorescence in Endoscopic Sinonasal and Skull Base Surgery Sinonasal Benign or Malignant Tumor Resection, Skull Base Surgery (Assessment of Nasoseptal Flap), Endoscopic Sinus Surgery - Chronic Sinusitis, Tumor of Nasal Sinus | Not applicable | Unknown | St. Paul's Sinus Centre | 40 | 2023-01-01 | 2022-11-14 |
| Phase 2 Study of Bintrafusp Alfa in Recurrent/Metastatic Olfactory Neuroblastoma (BARON). Bintrafusp alfa/M7824, Ibuprofen, PET scan - Olfactory Neuroblastoma, Esthesioneuroblastoma | Phase 2 | Completed | National Cancer Institute (NCI) | 11 | 2022-06-21 | 2025-08-08 |
| The Head and Neck Registry of the European Reference Network on Rare Adult Solid Cancers observation - Head and Neck Cancer, Nasopharynx Cancer | Recruiting | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | 13600 | 2022-05-31 | 2026-04-03 | |
| Temporalis Myofascial Flap Effectiveness Temporalis Myofascial flap - Maxillary Sinus Neoplasms | Not applicable | Unknown | Assiut University | 3 | 2022-03-01 | 2022-03-28 |
| Induction Treatment in SCC of the Head and Neck Region - Concomitant Chemotherapy and Low-dose Radiotherapy Chemotherapy (carboplatin+paclitaxel) with concomitant low dose ionizing radiotherapy - Squamous Cell Carcinoma of Oral Cavity, Pharynx Carcinoma | Not applicable | Active not recruiting | Maria Sklodowska-Curie National Research Institute of Oncology | 40 | 2022-02-17 | 2026-10-16 |
| Intensity Modulated Proton or X-Ray Therapy After Surgery for Treatment of Head and Neck Cancer, the HEADLIGHT Study Cisplatin, Intensity-Modulated Proton Therapy, Quality-of-Life Assessment - Head and Neck Carcinoma, Head and Neck Carcinoma of Unknown Primary | Phase 2 | Active not recruiting | Mayo Clinic | 174 | 2022-02-16 | 2026-07-16 |
| Prospective Study of Sinonasal and Skull-base Tumours Management Nasal Neoplasm, Nasal Neoplasm Benign | Recruiting | University Medical Centre Ljubljana | 120 | 2022-01-01 | 2026-04-29 | |
| Endoscopic Surgery in the Treatment of Soft Tissue Sarcoma in Nasal and Paranasal Sinus endoscopic surgery - Sarcoma,Soft Tissue, Nasal Cavity Cancer | Unknown | Eye & ENT Hospital of Fudan University | 40 | 2021-06-12 | 2022-11-14 | |
| Customized 3D Printed Oral Stents During Head and Neck Radiotherapy Best Practice, Medical Device Usage and Evaluation - Head and Neck Carcinoma, Malignant Parotid Gland Neoplasm | Phase 2 | Active not recruiting | M.D. Anderson Cancer Center | 88 | 2021-05-26 | 2026-10-06 |
| Camrelizumab Plus Chemoradiotherapy for Patients With Locoregional Cancer of Nasal Cavity and Paranasal Sinuses camrelizumab - Nasal Cavity Cancer, Paranasal Sinus Cancer | Phase 2 | Unknown | Sun Yat-sen University | 57 | 2021-04-16 | 2021-11-10 |
| Exercise Training and Behavioral Modification for the Improvement of Physical Activity in Head and Neck Cancer Patients Undergoing Cancer Treatment Medical Device Usage and Evaluation, Consultation, Exercise Intervention - Head and Neck Carcinoma, Hypopharyngeal Carcinoma | Not applicable | Completed | Thomas Jefferson University | 12 | 2021-03-28 | 2025-05-22 |
| Celecoxib Through Surgery and Radiation Therapy for the Treatment of Advanced Head and Neck Cancer Celecoxib, Placebo, Quality-of-Life Assessment - Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Phase 2 | Terminated | University of Utah | 13 | 2019-11-27 | 2025-02-12 |
| Tabelecleucel in Combination With Pembrolizumab in Subjects With Epstein-Barr Virus-associated Nasopharyngeal Carcinoma (EBV+ NPC) Tabelecleucel, Pembrolizumab - Nasopharyngeal Carcinoma, Nasopharyngeal Neoplasms | Phase 1 / Phase 2 | Terminated | Atara Biotherapeutics | 12 | 2019-02-19 | 2024-11-14 |
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Paranasal Sinus Neoplasms (24) · Laryngeal Neoplasms (14) · Head and Neck Neoplasms (10) · Mouth Neoplasms (10) · Hypopharyngeal Neoplasms (8) · Oropharyngeal Neoplasms (8) · Nasopharyngeal Neoplasms (7) · Pharyngeal Neoplasms (6) · Salivary Gland Neoplasms (6) · Nasopharyngeal Carcinoma (5) · Breast Neoplasms (4) · Carcinoma (4) · Lung Neoplasms (4) · Carcinoma, Adenoid Cystic (3)
Nose Diseases (35) · Respiratory Tract Diseases (35) · Respiratory Tract Neoplasms (35) · Neoplasms by Site (34) · Otorhinolaryngologic Diseases (34) · Neoplasms (33) · Otorhinolaryngologic Neoplasms (33) · Paranasal Sinus Diseases (26) · Head and Neck Neoplasms (25) · Pharyngeal Diseases (19) · Stomatognathic Diseases (19) · Laryngeal Diseases (14) · Pharyngeal Neoplasms (14) · Neoplasms by Histologic Type (13)
Cisplatin (6) · Radiotherapy (5) · Carboplatin (3) · Docetaxel (3) · Fluorouracil (3) · 1,2-diaminocyclohexaneplatinum II citrate (2) · Celecoxib (2) · Drug Therapy (2) · Hydroxyurea (2) · Magnetic Resonance Spectroscopy (2) · Platinum (2) · Specimen Handling (2) · Behavior Therapy (1) · CP protocol (1) · CTLA-4 Antigen (1)
National Cancer Institute (NCI) (3) · Assiut University (2) · Johnny Kao (2) · M.D. Anderson Cancer Center (2) · Memorial Sloan Kettering Cancer Center (2) · Sun Yat-sen University (2) · Atara Biotherapeutics (1) · Burzynski Research Institute (1) · Dana-Farber Cancer Institute (1) · Eye & ENT Hospital of Fudan University (1) · Fondazione IRCCS Istituto Nazionale dei Tumori, Milano (1) · Hospices Civils de Lyon (1) · Hôpital NOVO (1) · Maria Sklodowska-Curie National Research Institute of Oncology (1) · Mayo Clinic (1)
United States (21) · China (4) · France (3) · Croatia (1) · Czechia (1) · Egypt (1) · Germany (1) · Guam (1) · Italy (1) · Malaysia (1) · Poland (1) · Russia (1) · Singapore (1) · Slovenia (1) · Spain (1)
Charalampos Floudas, M.D. (2) · Aditi Mehta, DO (1) · Amit Agrawal (1) · Anna Lee (1) · Annalisa Trama, MD (1) · Bhishamjit Chera, MD (1) · C. Jillian Tsai, MD (1) · Domen Vozel, MD, PhD (1) · Ehab Y Hanna (1) · Everett Vokes, M.D. (1) · Haitao Wu, Phd (1) · Johnny Kao, M.D. (1)
PMID 20830768, PMID 21246519, PMID 31969335, PMID 33362722, PMID 33882143, PMID 34380663, PMID 34716198, PMID 36928072, PMID 38243705, PMID 38358334, PMID 39067873, PMID 39241963, PMID 39343510, PMID 39417692, PMID 39500789, PMID 39583952, PMID 39856213, PMID 40402690, PMID 40588371, PMID 41560283, PMID 41672597, PMID 41892875, PMID 41995270, PMID 42307670, PMID 42499790
P30CA042014 (1), U10CA180888 (1)