3 completed, 2 unknown, 1 active not recruiting, 1 terminated. 7 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 7 | Completed 3, Unknown 2, Active not recruiting 1, Terminated 1 |
Follow Schizophrenia, Treatment-Resistant: new trials by email Literature Review of Schizophrenia, Treatment-Resistant trials Research Report on Schizophrenia, Treatment-Resistant
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Τhe Combination of Pharmacotherapy With RECOVERYTRSGR and RECOVERYTRSBDGR. Group A: (Clozapine, quietiapine, olanzapine, aripiprazole, zyprasidone, risperidone, asenapine, paliperidone, clopixol,anxiolytics: clonazepam, stedon, tavor antidepressants: seropram),, Group B (Pharmacotherapy and TAU) (Clozapine, quietiapine, olanzapine, aripiprazole, zyprasidone, risperidone, asenapine, paliperidone, clopixol, clonazepam, stedon, tavor, antidepressants,, Group C (Pharmacotherapy and Psychotherapy) Clozapine, quietiapine, olanzapine, aripiprazole, zyprasidone, risperidone, asenapine, paliperidone, clopixol, clonazepam, stedon, tavor, lithium, depakine - Treatment Resistant Schizophrenia, Treatment Resistant Bipolar Disorder | Phase 4 | Active not recruiting | Dr. Stavroula Rakitzi | 84 | 2025-06-04 | 2026-05-01 |
| Multidisciplinary Design to Optimize Schizophrenia Treatment Based on Multi-omics Data and Systems Biology Analysis Aripiprazole, Paliperidone - Schizophrenia, Treatment-resistant Schizophrenia | Phase 4 | Unknown | Consorcio Centro de Investigación Biomédica en Red (CIBER) | 244 | 2023-11-01 | 2023-09-29 |
| Dextromethorphan as an Augmentation Agent in Treatment-resistant Schizophrenia Dextromethorphan, Placebo - Treatment Resistant Schizophrenia | Phase 4 | Completed | All India Institute of Medical Sciences, Bhubaneswar | 40 | 2023-08-31 | 2025-05-09 |
| An Exploratory Analysis of Immune and Inflammatory Response Associated With Clozapine Clozapine, Antipsychotics,Other (non-Clozapine) - Treatment-resistant Schizophrenia | Phase 4 | Terminated | Ohio State University | 5 | 2023-08-16 | 2026-02-25 |
| Comparison of Maintenance ECT Versus Clozapine in Treatment-resistant Schizophrenia Bilateral M-ECT, Clozapine - Treatment Resistant Schizophrenia | Phase 4 | Completed | All India Institute of Medical Sciences, Bhubaneswar | 60 | 2019-02-01 | 2021-06-16 |
| Electroconvulsive Therapy (ECT) in Patients With Super Refractory Schizophrenia MECTA SPECTRUM 5000Q ECT, Sham ECT - Refractory Schizophrenia, Super Refractory Schizophrenia | Phase 4 | Unknown | University of Sao Paulo | 20 | 2010-02-01 | 2014-01-29 |
| Amisulpride Augmentation Therapy for Clozapine-resistant Schizophrenic Patients Amisulpride add-on, Placebo add-on - Treatment-resistant Schizophrenia | Phase 4 | Completed | National Health Research Institutes, Taiwan | 273 | 2006-05-01 | 2010-04-16 |
Schizophrenia (2) · Diabetes Mellitus (1) · Lipid Metabolism Disorders (1) · Non-alcoholic Fatty Liver Disease (1) · Psychotic Disorders (1)
Mental Disorders (7) · Schizophrenia Spectrum and Other Psychotic Disorders (7) · Schizophrenia (5) · Digestive System Diseases (1) · Endocrine System Diseases (1) · Fatty Liver (1) · Glucose Metabolism Disorders (1) · Liver Diseases (1) · Metabolic Diseases (1) · Nutritional and Metabolic Diseases (1)
Aripiprazole (3) · Clozapine (3) · Paliperidone Palmitate (3) · Risperidone (2) · Antidepressive Agents (1) · Antipsychotic Agents (1) · Citalopram (1) · Clonazepam (1) · Clopenthixol (1) · Dextromethorphan (1) · Drug Therapy (1) · Lithium (1) · Lurasidone Hydrochloride (1) · Olanzapine (1) · Psychotherapy (1)
All India Institute of Medical Sciences, Bhubaneswar (2) · Consorcio Centro de Investigación Biomédica en Red (CIBER) (1) · Dr. Stavroula Rakitzi (1) · National Health Research Institutes, Taiwan (1) · Ohio State University (1) · University of Sao Paulo (1)
India (2) · Brazil (1) · Greece (1) · Taiwan (1) · United States (1)
Dr. Polyxeni Georgila, M. D. (1) · Dr. Stavroula Rakitzi, PhD (1) · Javier Labad Arias, MD, PhD (1) · Sheng-Chang Wang, M.D.,M.Sc. (1)
PMID 10372604, PMID 10492856, PMID 15968344, PMID 16380684, PMID 16633199, PMID 17187911, PMID 19837567, PMID 25157964, PMID 25400359, PMID 25697225, PMID 26827129, PMID 27919182, PMID 28096876, PMID 29732913, PMID 35556138, PMID 41780197, PMID 9137112, PMID 9541337