11 completed, 3 unknown, 1 active not recruiting, 1 recruiting. 17 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 17 | Completed 11, Unknown 3, Active not recruiting 1, Recruiting 1, Withdrawn 1 |
Follow Rickets: new trials by email Literature Review of Rickets trials Research Report on Rickets
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Neutrophil Gelatinase-associated Lipocalin VS Vascular Calcification in Maintenance Hemodialysis Patients palicalcitol - Chronic Kidney Disease-Mineral and Bone Disorder | Phase 4 | Unknown | Xiaoyan Jia | 80 | 2023-04-01 | 2024-03-08 |
| PRevEnting FracturEs in REnal Disease - 1 Denosumab 60 mg/ml, Calcium and vitamin D prophylaxis, Monitoring of post-injection calcium and phosphate - Kidney Diseases, Dialysis; Complications | Phase 4 | Active not recruiting | Western University, Canada | 60 | 2022-06-11 | 2025-05-31 |
| Cholecalciferol Supplementation in Restless Leg Syndrome in Patients With Chronic Kidney Disease Vitamin D, Placebo Oral Tablet - Restless Leg Disorder, Renal Disease Bone | Phase 4 | Withdrawn | University of Sao Paulo General Hospital | 2022-03-31 | 2021-09-30 | |
| Treatment of Adynamic Bone Disorder With Parathyroid Hormone in Chronic Kidney Disease Teriparatide, DXA,VFA, X-ray, HR-pQCT, 18-F NAF PET/CT, Bone biopsy - Adynamic Bone Disease, Chronic Kidney Diseases | Phase 4 | Recruiting | Ditte Hansen | 48 | 2021-12-15 | 2024-04-23 |
| Study to Assess the Safety, Pharmacokinetics and Efficacy of KRN23 in Pediatric Chinese Patients With XLH KRN23 - X-linked Hypophosphatemia (XLH) | Phase 4 | Completed | Kyowa Kirin Co., Ltd. | 28 | 2021-11-01 | 2024-07-09 |
| Study to Assess the Safety, Pharmacokinetics and Efficacy of KRN23 in Adult Chinese Patients With XLH KRN23 - X-linked Hypophosphatemia (XLH) | Phase 4 | Completed | Kyowa Kirin Co., Ltd. | 18 | 2021-09-28 | 2024-07-09 |
| Examining the Effect of Burosumab on Muscle Function Burosumab Injection [Crysvita] - X-linked Hypophosphatemia | Phase 4 | Completed | Yale University | 10 | 2019-11-13 | 2023-08-24 |
| Burosumab in Children and Adolescents With X-linked Hypophosphatemia Burosumab Injection - Rare Diseases, X-linked Hypophosphatemia | Phase 4 | Unknown | Bicetre Hospital | 57 | 2018-03-18 | 2020-06-05 |
| Different Effects of Non-calcium Phosphate Binders on Serum Calcium Sevelamer Hydrochloride, Lanthanum Carbonate - Chronic Kidney Disease | Phase 4 | Completed | Medical University of Lodz | 34 | 2018-03-01 | 2021-07-27 |
| Efficacy and Safety of Cinacalcet in Ca, P and iPTH Levels in Patients With Mild, Moderate and Severe SHPT Cinacalcet HCl - Hyperparathyroidism; Secondary, Renal | Phase 4 | Completed | Kyowa Kirin China Pharmaceutical Co., Ltd. | 750 | 2017-04-19 | 2024-04-29 |
| Using Different Doses of Active Vitamin D Combined With Neutral Phosphate in Children With X-linked Hypophosphatemia Calcitriol - X-linked Hypophosphatemia | Phase 4 | Unknown | Peking Union Medical College Hospital | 100 | 2017-01-01 | 2019-01-30 |
| Post-approval Clinical Study of Asfotase Alfa Treatment for Patients With Hypophosphatasia (HPP) in Japan Asfotase Alfa - Hypophosphatasia | Phase 4 | Completed | Alexion Pharmaceuticals, Inc. | 13 | 2015-06-01 | 2017-05-08 |
| Zoledronic Acid to Prevent Bone Loss After Kidney Transplantation Zoledronic acid - Renal Osteodystrophy | Phase 4 | Completed | University of Sao Paulo General Hospital | 34 | 2012-07-01 | 2014-05-19 |
| Efficacy of Vitamin D2 to Treat Chronic Kidney Disease Mineral and Bone Disorder Vitamin D2, 1,25(OH)2 Vit D3 - Vitamin D Deficiency | Phase 4 | Completed | Dongliang Zhang, MD | 204 | 2012-07-01 | 2016-02-15 |
| Vitamin D Status in Males in Jerusalem Area and Its Correlation to Parathyroid Hormone (PTH) Level and Bone Mineral Density 25 OH vitamin D - Vitamin D Deficiency, Secondary Hyperparathyroidism | Phase 4 | Completed | Clalit Health Services | 210 | 2010-01-01 | 2014-07-21 |
| Vitamin D and Genetics in Nutritional Rickets Vitamin D + Calcium, Calcium, Vitamin D2 - Nutritional Rickets | Phase 4 | Completed | Mayo Clinic | 109 | 2004-01-01 | 2012-07-04 |
| Osteopenia and Renal Osteodystrophy: Evaluation and Management pamidronate - Osteopenia, Renal Osteodystrophy | Phase 4 | Completed | US Department of Veterans Affairs | 2002-10-01 | 2009-01-21 |
Chronic Kidney Disease-Mineral and Bone Disorder (9) · Familial Hypophosphatemic Rickets (5) · Vitamin D Deficiency (4) · Hyperparathyroidism, Secondary (3) · Bone Diseases (2) · Hyperparathyroidism (2) · Osteomalacia (2) · Renal Insufficiency, Chronic (2) · Bone Diseases, Metabolic (1) · Fractures, Bone (1) · Heart Diseases (1) · Hypophosphatasia (1) · Kidney Diseases (1) · Kidney Failure, Chronic (1)
Avitaminosis (17) · Calcium Metabolism Disorders (17) · Deficiency Diseases (17) · Malnutrition (17) · Metabolic Diseases (17) · Musculoskeletal Diseases (17) · Nutrition Disorders (17) · Nutritional and Metabolic Diseases (17) · Bone Diseases, Metabolic (16) · Bone Diseases (15) · Female Urogenital Diseases (14) · Female Urogenital Diseases and Pregnancy Complications (14) · Male Urogenital Diseases (14) · Urogenital Diseases (14)
burosumab (4) · Calcitriol (3) · Calcium (2) · Ergocalciferols (2) · Vitamin D (2) · Blood Specimen Collection (1) · Calcium Carbonate (1) · Cholecalciferol (1) · Cinacalcet (1) · Denosumab (1) · Heart Function Tests (1) · Pamidronate (1) · Restraint, Physical (1) · Sevelamer (1) · Teriparatide (1)
Kyowa Kirin Co., Ltd. (2) · University of Sao Paulo General Hospital (2) · Alexion Pharmaceuticals, Inc. (1) · Bicetre Hospital (1) · Clalit Health Services (1) · Ditte Hansen (1) · Dongliang Zhang, MD (1) · Kyowa Kirin China Pharmaceutical Co., Ltd. (1) · Mayo Clinic (1) · Medical University of Lodz (1) · Peking Union Medical College Hospital (1) · US Department of Veterans Affairs (1) · Western University, Canada (1) · Xiaoyan Jia (1) · Yale University (1)
China (6) · Brazil (2) · United States (2) · Canada (1) · Denmark (1) · France (1) · Israel (1) · Nigeria (1) · Poland (1)
Aihua Zhang (1) · Aili Jiang (1) · Anat Tsur, MD (1) · Chaosheng Chen (1) · Ditte Hansen, MD, PhD (1) · Dongliang Zhang, Doctor (1) · Elias David-Neto, MD (1) · Guanqing Xiao (1) · Guohua Ding (1) · Hong Liu (1) · Jianming Ye (1) · Jianying Niu (1) · Jiazhuang Lou (1) · Jing Chen (1) · Junwei Yang (1)
PMID 24748637, PMID 33305842, PMID 34754193, PMID 40935429
2018 (1)