17 completed, 10 unknown, 6 recruiting, 4 not yet recruiting. 28 Not applicable, 4 Phase 4, 2 Phase 1, 2 Phase 2, 2 Phase 3.
Follow Reversible Pulpitis: new trials by email Literature Review of Reversible Pulpitis trials Research Report on Reversible Pulpitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Hemostatic Agents on TheraCal PT Pulpotomy Success in Primary Molars 2.5% Sodium Hypochlorite applied to pulpal tissue/stumps for 3 minutes to achieve hemostasis prior to TheraCal PT placement during primary molar pulpotomy and 15% Ferric Sulfate (Astringedent™ 15.5%) - Reversible Pulpitis, Dental Caries | Not applicable | Not yet recruiting | Reem Mohamed Gaber | 75 | 2027-01-01 | 2026-10-15 |
| Comparative Evaluation of Direct Pulp Capping Between Deep and Extremely Deep Caries in Mature Permanent Mandibular Molars . Direct pulp capping in extremely deep carious lesion., Direct pulp capping in deep carious lesion. - Reversible Pulpitis, Deep Caries | Not applicable | Recruiting | Postgraduate Institute of Dental Sciences Rohtak | 130 | 2026-04-29 | 2026-07-28 |
| Influence of Proximal Caries on Outcome of Direct Pulp Capping in Permanent Mandibular Molars With Reversible Pulpitis Direct pulp capping in proximal carious lesion, Direct pulp capping in occlusal carious lesion - Reversible Pulpitis, Extremely Deep Caries | Not applicable | Recruiting | Postgraduate Institute of Dental Sciences Rohtak | 154 | 2026-04-29 | 2026-06-10 |
| Comparative Evaluation of Calcium Silicate-doped Treated Dentin Matrix and Mineral Trioxide Aggregate as Miniature Pulpotomy Biomaterials in Deep Carious Lesions Calcium Silicate doped treated dentin matrix for miniature pulpotomy (CaSi+hTDM MP)., Mineral Trioxide Aggregate (MTA) for Miniature Pulpotomy - Reversible Pulpitis, Deep Carious Lesions | Not applicable | Not yet recruiting | All India Institute of Medical Sciences | 56 | 2026-04-25 | 2026-03-10 |
| Predicting Vital Pulp Treatment Outcomes in Symptomatic Pulpits Using Metabolic Biomarker vital pulp treatment - Pulp Disease, Dental, Pulpitis | Not applicable | Recruiting | Abeer Ghalib Abdul-khaliq | 60 | 2026-02-20 | 2026-04-01 |
| Outcome of Direct Pulp Capping and Partial Pulpotomy in Reversible Pulpitis Partial Pulpotomy in Reversible Pulpitis, Direct pulp capping with MTA - Reversible Pulpitis, Extremely Deep Caries | Not applicable | Not yet recruiting | Postgraduate Institute of Dental Sciences Rohtak | 138 | 2025-12-10 | 2025-12-23 |
| Direct Pulp Capping With Biodentine in Permanent Teeth With Reversible Pulpitis Direct pulp capping with Biodentine - Reversible Pulpitis, Dental Pulp Exposure | Not applicable | Completed | University of Medicine and Pharmacy at Ho Chi Minh City | 12 | 2025-11-05 | 2026-10-14 |
| Biomarkers for Differentiating Reversible and Irreversible Pulpitis Pulpal Blood Biomarker Analysis - Reversible Pulpitis, Irreversible Pulpitis | Completed | Safa | 90 | 2025-11-01 | 2026-07-31 | |
| Pain Management in Teeth With Reversible Pulpitis Ibuprofen 10 mg/kg - Reversible Pulpitis, Ibuprofen | Early Phase 1 | Completed | Inonu University | 46 | 2025-08-02 | 2025-09-24 |
| Comparison of IL-8, FGF-1 and VEGF Levels in Pulpal Tissue, GCF and Dentinal Fluid Samples of Healthy, Reversible and Irreversible Pulpitis Diagnosed Teeth Pulpitis, Pulp Inflammation | Completed | Kırıkkale University | 51 | 2025-03-03 | 2025-12-05 | |
| Evaluation of Pulpal Biomarkers in Vital Pulp Therapy Vital pulp therapy - Reversible Pulpitis, Irreversible Pulpitis | Not applicable | Active not recruiting | ertuğrul karataş | 50 | 2025-03-03 | 2025-07-20 |
| Caries Location and Its Effect on the Success Rate of Indirect Pulp Treatment in Primary Molars Indirect Pulp Treatment - Deep Caries Lesion of Primary Teeth, Dental Pulp Diseases | Not applicable | Not yet recruiting | Cairo University | 50 | 2024-12-01 | 2024-11-05 |
| In Vivo Pulp Thermal Changes During Different Slenderization Techniques High-Speed Air-Driven Drill (Airotor and Bur), Orthodontic IPR Kit (Oscillating System) - Irreversible Pulpitis, Reversible Pulpitis | Not applicable | Active not recruiting | Armed Forces Institute of Dentistry, Pakistan | 30 | 2024-09-29 | 2026-02-17 |
| The Effect of Different Risk Factors on the Success Rate of VPT with Biodentine, with MTA - Dental Caries Extending to Pulp, Pulp Disease, Dental | Recruiting | Semmelweis University | 400 | 2024-06-01 | 2025-03-06 | |
| Comparative Evaluation of Indirect vs. Direct Pulp Capping in Deep Carious Mandibular Molars INDIRECT AND DIRECT PULP CAPPING AFTER PARTIAL OR COMPLETE CARIES REMOVAL IN DEEPLY CARIOUS MATURE PERMANENT MANDIBULAR MOLARS WITH MODERATE PULPITIS - Indirect Pulp Capping, Reversible Pulpitis | Not applicable | Recruiting | Postgraduate Institute of Dental Sciences Rohtak | 106 | 2024-05-23 | 2026-02-12 |
| Direct Pulp Capping Agent on Human Pulp Tissue Biodentine, Mineral Tri-Oxide Aggregate, THERACAL LC - Reversible Pulpitis | Phase 4 | Completed | DR SURINDER SACHDEVA | 40 | 2024-04-28 | 2026-10-08 |
| Assessment of Pain and Anxiety During Infiltration Anesthesia Using Dental Anesthesia Injector Versus Conventional Syringe in Pediatric Patients Dental Anesthesia Injector, conventional syringe - Dental Caries, Reversible Pulpitis | Not applicable | Recruiting | Ain Shams University | 40 | 2024-01-25 | 2025-08-03 |
| TheraCal PT vs. Formocresol in Primary Molar Pulpotomies Dual cured resin modified - Reversible Pulpitis | Phase 1 / Phase 2 | Completed | Hama University | 50 | 2024-01-01 | 2026-10-07 |
| Effectiveness of Biodentine v/s Calcium Hydroxide as Indirect Pulp Capping Materials Biodentine - Indirect Pulp Capping, Calcium Hydroxide - Indirect Pulp Capping - Reversible Pulpitis | Not applicable | Completed | Zahoor khan | 76 | 2023-02-05 | 2025-09-15 |
| Role Of Wound Lavage in Direct Pulp Capping Of Permanent Teeth With Carious Exposure wound lavage with normal saline, wound lavage with sodium hypochlorite, wound lavage with Ethylenediaminetetraacetic acid(EDTA) - Reversible Pulpitis | Not applicable | Unknown | Postgraduate Institute of Dental Sciences Rohtak | 140 | 2022-11-01 | 2023-12-08 |
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Dental Caries (7) · Pulpitis (6) · Dental Pulp Diseases (5) · Dental Pulp Exposure (3) · Toothache (2) · Bicuspid Aortic Valve Disease (1) · Dental Pulp Necrosis (1)
Stomatognathic Diseases (16) · Tooth Diseases (16) · Dental Pulp Diseases (7) · Tooth Demineralization (7) · Pathological Conditions, Signs and Symptoms (3) · Facial Pain (2) · Neurologic Manifestations (2) · Pain (2) · Signs and Symptoms (2) · Aortic Valve Disease (1) · Cardiovascular Abnormalities (1) · Cardiovascular Diseases (1) · Congenital Abnormalities (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Heart Defects, Congenital (1)
Pemetrexed (7) · tricalcium silicate (5) · mineral trioxide aggregate (3) · Dycal (2) · Pulpotomy (2) · TheraCal (2) · Calcium Hydroxide (1) · Chlorhexidine (1) · Edetic Acid (1) · Electrosurgery (1) · Ibuprofen (1) · Polymerase Chain Reaction (1) · ProRoot MTA (1) · Saline Solution (1) · Septodont (1)
Postgraduate Institute of Dental Sciences Rohtak (8) · Ain Shams University (4) · Cairo University (2) · Jordan University of Science and Technology (2) · King's College London (2) · Abeer Ghalib Abdul-khaliq (1) · All India Institute of Medical Sciences (1) · Armed Forces Institute of Dentistry, Pakistan (1) · Charite University, Berlin, Germany (1) · DR SURINDER SACHDEVA (1) · Ege University (1) · Hama University (1) · Inonu University (1) · Kırıkkale University (1) · Mansoura University (1)
India (8) · Egypt (6) · Turkey (Türkiye) (6) · Jordan (2) · Pakistan (2) · United States (2) · Denmark (1) · Hungary (1) · Iraq (1) · Lithuania (1) · Norway (1) · Spain (1) · Syria (1) · United Kingdom (1) · Vietnam (1)
Dr. Pankaj Sangwan, MDS (2) · Abeer G Abdulkhaliq (1) · Alaina Tariq Mughal, BDS, FCPS (R) (1) · Anas F Mahdee, professor (1) · Bao Chau T Vu, DDS, PhD (1) · Carolyn A Kerins, DDS, PhD (1) · Dr. Vinay Kumar, MDS (1) · Falk Schwendicke, Prof. (1) · Francesco Mannocci (1) · Gerald A Ferretti, DDS, MS, MPH (1)
PMID 36890738, PMID 16416713, PMID 20572864, PMID 22888399, PMID 25710953, PMID 26079388, PMID 27766712, PMID 27837343, PMID 27891629, PMID 28190299, PMID 28410008, PMID 28822566, PMID 29738286, PMID 30232625, PMID 31096259, PMID 32194986, PMID 32854206, PMID 32950193, PMID 33404764, PMID 35887779, PMID 37124935, PMID 37634915, PMID 39176161, PMID 39215293, PMID 39372577, PMID 39442480, PMID 39935864, PMID 41652862, PMID 41972792