3 completed, 2 terminated, 2 unknown, 1 not yet recruiting. 4 Not applicable, 2 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Completed 1, Not yet recruiting 1, Recruiting 1, Terminated 1 |
| Phase 2 | 2 | Completed 1, Terminated 1 |
| Phase 1 | 1 | Terminated 1 |
| Phase 3 | 1 | Completed 1 |
Follow Respiratory Acidosis: new trials by email Literature Review of Respiratory Acidosis trials Research Report on Respiratory Acidosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of the Effects on Carbon Dioxide (paCO2) of a New Oronasal Mask in Patients With Severe COPD Exacerbation Requiring Non-Invasive Mechanical Ventilation OptiNIV, Visairo - COPD, Respiratory Acidosis | Not applicable | Not yet recruiting | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 21 | 2025-08-01 | 2025-07-23 |
| VentilO Prospective Study Clinicians, VenitlO - Mechanical Ventilation Complication, Respiratory Acidosis | Not applicable | Recruiting | Laval University | 76 | 2025-04-24 | 2025-09-04 |
| Efficacy of Volume Ventilation in Patients With Acute Respiratory Failure at Risk of Obstructive Apneas or Obesity Hypoventilation AVAPS-AE mode during NIV, S/T mode during NIV - Acute Respiratory Failure, Hypercapnic Respiratory Failure | Not applicable | Terminated | University Hospital, Rouen | 14 | 2019-12-04 | 2026-04-15 |
| Determination of the Dissociation Constant (Ka) of Plasma and Whole Blood in Septic Patients In vitro determination the dissociation constant (Ka) and total amount of non-volatile buffers (Atot) in isolated plasma., In vitro determination the dissociation constant (Ka) and total amount of non-volatile buffers (Atot) in whole blood, Biomolecular analysis of plasma proteins. - Sepsis, Septic Shock | Unknown | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | 90 | 2019-06-03 | 2019-06-04 | |
| THRIVE Apneic Ventilation With Standardized Airway Management During General Anesthesia. Apneic ventilation - Apnea, Ventilation Therapy; Complications | Unknown | Copenhagen University Hospital, Rigshospitalet | 36 | 2019-01-08 | 2019-01-23 | |
| Non Carbonic Buffer Power of Critical Ill Patients With Sepsis In vitro determination of non-carbonic buffer power, Classic description of acid-base status - Acid-Base Imbalance, Respiratory Acidosis | Completed | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | 36 | 2018-03-07 | 2019-04-25 | |
| FIRST-line Support for Assistance in Breathing in Children (FIRST-ABC) Feasibility Study Treatment strategy: Non-invasive respiratory support delivered via high flow nasal cannula, Treatment strategy: Non-invasive respiratory support delivered via continuous positive airway pressure - Hypoxia, Respiratory Acidosis | Phase 2 / Phase 3 | Completed | Great Ormond Street Hospital for Children NHS Foundation Trust | 121 | 2015-11-01 | 2016-12-16 |
| Clinical Study to Determine the Optimal Operation Parameters During CO2 Removal With the Abylcap® System Abylcap® System: blood flow (QB): 200mL/min; gas flow (QG):7L/min, Abylcap® System: blood flow (QB): 300mL/min; gas flow (QG):7L/min, Abylcap® System: blood flow (QB): 400mL/min; gas flow (QG):7L/min - ARDS (Acute Respiratory Distress Syndrome), Respiratory Acidosis | Not applicable | Completed | University Hospital, Ghent | 4 | 2014-02-20 | 2022-12-29 |
| Inhaled Nitric Oxide in Neonates With Elevated A-a DO2 Gradients Not Requiring Mechanical Ventilation nitric oxide for inhalation, Oxygen - Lung Disease, Hypoxemia | Phase 1 / Phase 2 | Terminated | Mallinckrodt | 7 | 2002-05-01 | 2016-10-19 |
Acidosis, Respiratory (9) · Acid-Base Imbalance (2) · Alkalosis, Respiratory (2) · Apnea (2) · Hypoxia (2) · Acidosis (1) · Acute Lung Injury (1) · Critical Illness (1) · Dyspnea (1) · Hypercapnia (1) · Lung Diseases (1) · Lymphoma, Follicular (1) · Obesity (1) · Pulmonary Disease, Chronic Obstructive (1) · Respiratory Insufficiency (1)
Metabolic Diseases (9) · Nutritional and Metabolic Diseases (9) · Respiration Disorders (9) · Respiratory Tract Diseases (9) · Acidosis (8) · Respiratory Insufficiency (8) · Acid-Base Imbalance (7) · Pathological Conditions, Signs and Symptoms (6) · Signs and Symptoms (4) · Signs and Symptoms, Respiratory (4) · Alkalosis (2) · Disease Attributes (2) · Hyperventilation (2) · Lung Diseases (2) · Pathologic Processes (2)
Endothelium-Dependent Relaxing Factors (1) · Inhalation (1) · Nitric Oxide (1) · Nurse Clinicians (1) · Oxygen (1)
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico (2) · Copenhagen University Hospital, Rigshospitalet (1) · Great Ormond Street Hospital for Children NHS Foundation Trust (1) · IRCCS Azienda Ospedaliero-Universitaria di Bologna (1) · Laval University (1) · Mallinckrodt (1) · University Hospital, Ghent (1) · University Hospital, Rouen (1)
Italy (3) · Belgium (1) · Canada (1) · Czechia (1) · Denmark (1) · France (1) · United Kingdom (1) · United States (1)
Giacomo Grasselli, MD (2) · Thomas Langer, MD (2) · Antoine Cuvelier, MD, PhD (1) · Antonio M Pesenti, MD (1) · Antonio Pesenti, MD (1) · Frantisek Duska, MD (1) · Michael S Kristensen, MD (1) · Padmanabhan Ramnarayan (1) · Paul Elbers, MD (1) · Sunny Eloot, PhD, MScBME, MScCivE (1) · Waldemar Carlo, MD (1)