9 completed, 9 unknown, 4 recruiting, 3 terminated. 29 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 29 | Completed 9, Unknown 9, Recruiting 4, Terminated 3, Not yet recruiting 2, Withdrawn 2 |
Follow Refractory Epilepsy: new trials by email Literature Review of Refractory Epilepsy trials Research Report on Refractory Epilepsy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Characterisation of Laryngeal Evoked Potentials Induced by Vagus Nerve Stimulation in Refractory Epilepsy Patients Increasing VNS Intensities Induced with Magnet - Refractory Epilepsy, Epilepsy | Not applicable | Not yet recruiting | Université Catholique de Louvain | 110 | 2027-01-01 | 2026-10-29 |
| Characterising the Network-Specific Effects of Piriform Cortex Stimulation Via SEEG SEEG recordings and SPES - Refractory Epilepsy, Neuromodulation | Not applicable | Not yet recruiting | Xuanwu Hospital, Beijing | 10 | 2025-12-08 | 2025-12-26 |
| Self-administered ONe-of-a Kind Approach to Epilepsy Therapy Through a Web-based Music Application Experimental Intervention (Music A), Active Comparator Intervention (Music B), Active Comparator Intervention (Music C) - Epilepsy, Refractory Epilepsy | Not applicable | Recruiting | Dartmouth-Hitchcock Medical Center | 24 | 2025-07-22 | 2026-05-20 |
| Investigating the Functional Characteristics During Wakefulness and Sleep Based on SEEG SEEG recordings and SPES - Refractory Epilepsy, Sleep | Not applicable | Recruiting | Xuanwu Hospital, Beijing | 20 | 2024-07-08 | 2025-06-27 |
| Investigating the Role and Electrophysiological Characteristics of the Human Claustrum Based on SEEG Direct Electrical Stimulation - Refractory Epilepsy, Consciousness, Loss of | Not applicable | Completed | Xuanwu Hospital, Beijing | 8 | 2024-05-27 | 2025-07-11 |
| High Definition Transcranial Direct Current Stimulation (HD-tDCS) for Refractory Epilepsy Active Comparator: Unilateral real High definition transcranial direct current stimulation, Active Comparator: Bilateral real High definition transcranial direct current stimulation, Sham Comparator: Sham High definition transcranial direct current stimulation - Transcranial Direct Current Stimulation, EEG | Not applicable | Unknown | Anhui Medical University | 90 | 2024-02-12 | 2024-02-20 |
| Effect of Blue Light on Vagus Nerve Stimulation in Patients With Refractory Epilepsy electroencephalography, electrocardiogram, pupillometry, evoked potentials, light administration, transcutaneous vagus nerve stimulation, electroencephalography, pupillometry, electrocardiogram, light administration - Refractory Epilepsy | Not applicable | Recruiting | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | 34 | 2023-07-01 | 2026-11-02 |
| Optimal Stimulation Parameters to Disrupt Epileptiform Activity Neurostimulation - Refractory Epilepsy | Not applicable | Completed | Massachusetts General Hospital | 16 | 2023-06-13 | 2026-09-02 |
| A Study to Evaluate fMRI of Active DBS Stimulation in Epilepsy Functional magnetic resonance imaging (fMRI) - Refractory Epilepsy | Not applicable | Withdrawn | Mayo Clinic | 2022-09-01 | 2022-11-01 | |
| Modulation of Emotion Perception in Humans Via Amygdala Stimulation Electrical Stimulation - Refractory Epilepsy | Not applicable | Completed | Dartmouth-Hitchcock Medical Center | 16 | 2022-03-31 | 2025-09-22 |
| Identification of Biomarkers for Vagus Nerve Stimulation in Patients With Refractory Epilepsy Vagus nerve stimulation - Refractory Epilepsy | Not applicable | Recruiting | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | 20 | 2022-02-28 | 2026-11-02 |
| Pivotal-Safety and Therapeutic Measures of tDCS in Patients With Refractory Focal Epilepsy STARSTIM device, Sham Device - Refractory Epilepsy, Focal Seizure | Not applicable | Completed | Neuroelectrics Corporation | 127 | 2021-10-25 | 2026-04-08 |
| Exercise as Adjunctive Treatment for Refractory Epilepsy Exercise program, Health Coach, Health Information - Refractory Epilepsy, Epilepsy | Not applicable | Terminated | Wake Forest University Health Sciences | 10 | 2021-04-13 | 2022-12-07 |
| Localization of the Reward Positivity to ACC Virtual T-maze task - Refractory Epilepsy | Not applicable | Unknown | University Hospital, Ghent | 40 | 2021-03-04 | 2024-01-05 |
| Efficacy and Safety of Perampanel in Combination in Glioma-refractory Epilepsy Perampanel, conventional antiepileptic treatment - Refractory Epilepsy | Not applicable | Withdrawn | Assistance Publique Hopitaux De Marseille | 2021-02-15 | 2022-06-27 | |
| Galactose Supplementation for the Treatment of MOGHE D-Galactose - Refractory Epilepsy, SLC35A2-CDG - Solute Carrier Family 35 Member A2 Congenital Disorder of Glycosylation | Not applicable | Unknown | Hospital Ruber Internacional | 8 | 2021-01-15 | 2021-04-06 |
| The Potential of a Low Glutamate Diet as a Treatment for Pediatric Epilepsy Low Glutamate diet - Epilepsy in Children, Epilepsy in Youth | Not applicable | Completed | American University | 45 | 2020-10-15 | 2022-07-20 |
| Tele-epic (Telemedicine for Epilepsy Care) Telemedicine - Epilepsy, Epileptic Encephalopathy | Not applicable | Unknown | Azienda Usl di Bologna | 600 | 2020-07-09 | 2022-02-16 |
| Safety of Using NaviFUS System in Patients With Drug Resistant Epilepsy NaviFUS System - Drug Resistant Epilepsy, Epilepsy, Drug Resistant | Not applicable | Completed | NaviFUS Corporation | 6 | 2019-06-17 | 2020-11-13 |
| Novel Network Analysis of Intracranial Stereoelectroencephalography Combined Micro-Macro SEEG Electrodes - Epilepsy in Children, Focal Epilepsy | Not applicable | Unknown | Great Ormond Street Hospital for Children NHS Foundation Trust | 20 | 2019-06-16 | 2021-11-19 |
Showing 20 of 29. Sign in to see all of them.
Drug Resistant Epilepsy (29) · Epilepsy (5) · Epilepsies, Partial (1) · Epilepsy, Tonic-Clonic (1) · Hypersensitivity (1) · Mental Disorders (1) · Motor Activity (1) · Seizures (1) · Unconsciousness (1)
Brain Diseases (29) · Central Nervous System Diseases (29) · Nervous System Diseases (29) · Epilepsy (24) · Neurologic Manifestations (2) · Pathological Conditions, Signs and Symptoms (2) · Signs and Symptoms (2) · Behavior (1) · Consciousness Disorders (1) · Epilepsy, Generalized (1) · Immune System Diseases (1) · Neurobehavioral Manifestations (1)
Transcranial Direct Current Stimulation (2) · Electric Stimulation (1) · Evoked Potentials (1) · Exercise (1) · Galactose (1) · Magnetic Resonance Imaging (1) · Resistance Training (1) · SpeA protein, Streptococcus pyogenes (1) · Telemedicine (1) · Vagus Nerve Stimulation (1) · perampanel (1)
Xuanwu Hospital, Beijing (3) · Beijing Pins Medical Co., Ltd (2) · Cliniques universitaires Saint-Luc- Université Catholique de Louvain (2) · Dartmouth-Hitchcock Medical Center (2) · Neuroelectrics Corporation (2) · University Hospital, Ghent (2) · American University (1) · Anhui Medical University (1) · Assistance Publique Hopitaux De Marseille (1) · Azienda Usl di Bologna (1) · Copenhagen University Hospital, Rigshospitalet (1) · Great Ormond Street Hospital for Children NHS Foundation Trust (1) · Hospital Ruber Internacional (1) · Kessler Foundation (1) · Massachusetts General Hospital (1)
United States (8) · China (6) · Belgium (5) · Spain (3) · Denmark (2) · France (2) · Italy (2) · Austria (1) · Czechia (1) · Germany (1) · Portugal (1) · Romania (1) · Sweden (1) · Taiwan (1) · United Kingdom (1)
Liankun Ren (2) · Alfred Meurs, MD PhD (1) · Andreas Schulze Bonhage, MD (1) · Angel Aledo-Serrano, MD, PhD (1) · Baomin Li (1) · Brian C Fidali, MD (1) · Carla Bente, MD (1) · Catherine Chu, MD (1) · Elinor Ben-Menachem, MD,PhD (1) · Fei Yin (1) · Feng Gao (1) · Francisco Sales, MD (1) · Halley Alexander, MD (1) · Hsiang-Yu Yu, M.D. (1)
PMID 30642370, PMID 34862297, PMID 35132096, PMID 35833911, PMID 36867910, PMID 42401244
R01NS119483 (1), R21MH124674 (1)